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Modified Radical Mastectomy Valerie L. Staradub, MD, and Monica Morrow, MD urgical management options for breast cancer include modified radical mastectomy (MRM), MRM with immediate reconstruction, and breast conservation therapy (BCT). Absolute contraindications to BCT include tumor presence in more than one breast quadrant, diffuse suspicious or indeterminate calcifications seen on mammography and contraindications to radiation therapy, such as first or second trimester of pregnancy or history of radiation therapy to the breast field for previous breast cancer or as part of treatment for another condition, such as Hodgkin's disease. 1 Relative contraindications include sufficiently large tumor-to-breast ratio to preclude acceptable cosmesis and collagen vascular disease. The incidence of these contraindications varies with tumor stage. In our experience, 10% of w o m e n with stage I breast cancer and 28% of w o m e n with stage II breast cancer had contraindications to B e T . 2 In w o m e n with contraindications to BCT, MRM is medically necessary. For all others, there is no survival difference between the procedures, and patient preference should be the deciding factor. We have observed that approximately 20% of w o m e n who are candidates for BCT opt to undergo MRM. Nationally, MRM remains the most common treatment for patients with stage I and II breast cancer. 3-5 In some situations, MRM is not an appropriate first-line treatment modality, and the patient should be referred for neoadjuvant chemotherapy; these include metastatic breast cancer and locoregionally advanced carcinoma. 6-7 In addition, patients presenting with stage IV carcinoma are surgical candidates only if they develop local complications that cannot be controlled with systemic therapy. MRM always includes removal of the breast tissue, the nipple-areolar complex, and the ipsilateral axillary lymph nodes. Variations of the procedure, including removal of the pectoralis minor muscle or division of its tendon to S facilitate axillary exposure, have been described, sq~ In our experience, these are rarely, if ever, necessary, and the technique that we describe keeps the pectoralis minor intact. The original descriptions of MRM included removal of the pectoralis major fascia, because this structure was thought to be a barrier to the lymphatic spread of tumor. Subsequent studies have shown that lymphatic vessels penetrate the pectoral fascia and that this fascia may be preserved when needed to facilitate implant reconstruction, as long as care is taken to meticulously remove all of the breast tissue superficial to the fascia. MRM is an extremely safe operation with a very- low operative mortality rate. This is true even in the elderly population, for which the mortality rate from breast surgery of all types is less than 2%. 11-14 Patient Positioning and Preparation 1"he patient is positioned supine on the operating table with the ipsilateral arm abducted 90 ~ on an arm board. The arm board is padded to prevent subluxation of the shoulder with brachial plexus stretch. The patient is positioned at the edge of the table on the operative side; it may be helpful to place a folded sheet under the ipsilateral shoulder. The axilla is shaved if necessary, and a standard surgical preparation is done. The breast preparation should extend below the mframammary crease, across the midline, and to the supraclavicular fossa in the event that extra skin mobilization is needed to allow closure. The entire ipsilateral arm is prepped to the wrist, the arm board is covered with a Mayo stand cover, and the arm is draped with an impervious stockinet. The field drapes are brought underneath the ipsilateral shoulder so that the entire arm is in the operative field. From the Lynn Sage Comprehensive Breast Center, Department of Surgery, Northwestern University Medical School, Chicago, IL. Address reprint requests to Monica Morrow, MD, Director, Lynn Sage Comprehensive Breast Center, Northwestern Memorial Hospital, 251 E. Huron St., Gaiter 13-174, Chicago, IL 60611. Copyright 9 2000 by WB. Saunders Company 1524-153X/00/0202-0005510.00/0 doi: 10.1053/otgn.2000.7066 118 Operative Techniques in General Surgery, Vol 2, No 2 (June), 2000: pp 118-126