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Pharmacology Tutoring
for Alcohol
By Alaina Darby
Which of the following is not true of ethanol?
a. It affects multiple organ systems
b.It acts as a CNS stimulant
c. It can impair prenatal organ development
d.The mechanism for its effects are not totally
understood
Which of the following is not true of ethanol
absorption?
a. Occurs via diffusion
b.Most rapid from the stomach
c. Impeded by food
d.Occurs throughout the GI tract
Which of the following is true of ethanol
elimination?
a. 95% is eliminated in breath, urine and sweat
b.Ethanol is oxidized by three enzymes
c. Ethanol is directly converted to acetaldehyde
d.Acetaldehyde accumulates when you drink
faster
Which of the following is the rate limiting step of
ethanol metabolism?
a. Conversion of ethanol to acetaldehyde by
alcohol dehydrogenase
b.Conversion of ethanol to acetaldehyde by
aldehyde dehydrogenase
c. Conversion of ethanol to acetic acid by alcohol
dehydrogenase
d.Conversion of ethanol to acetic acid by aldehyde
dehydrogenase
Which of the following accumulates due to
disulfram?
a. Ethanol
b.Acetaldehyde
c. Acetic acid
d.Aldehyde dehydrogenase
Which of the following does naltrexone inhibit?
a. Ethanol activation of dopamine system
b.Ethanol activation of serotonin system
c. Enzymatic oxidation of ethanol to acetic acid
d.Enzymatic oxidation of ethanol to acetaldehyde
Which of the following is not true of the action of
ethanol?
a. Activation of dopamine receptors
b.Activation of NMDA receptors
c. Activation of GABAA receptors
d.Activation of BK channels
e.Activation of 5-HT3 receptors
Which of the following would be the least
dangerous to take with ethanol due to GABA
enhancement?
a. Benzodiazepines
b.Opioids
c. Amphetamines
d.Barbiturates
Which of the following which of the following
vitamins is not inhibited by ethanol?
a. Niacin
b.Thiamine
c. B1
d.B6
For which of the following conditions does ethanol
have a beneficial effect?
a. CHF
b.Hypercholesterolemia
c. Hyperglycemia
d.Hypertension
Which of the following is an effect of both
Wernicke’s encephalopathy and cerebellar
degeneration?
a. Dementia
b.Memory loss
c. Nystagmus
d.Ataxia
Which of the following is an effect of excessive
ethanol intake that may lead to shrinkages of
brain matter due to thiamine deficiency?
a. Pancreatitis
b.Worsening of ulcers
c. Flattening of intestinal villi
d.Gastric bleeding
Which of the following is an effect of excessive
ethanol on the liver that causes alcohol liver
disease (ALD)?
a. Increased fat accumulation in the liver
b.Decreased fat accumulation in the liver
c. Increased blood flow to the liver
d.Decreased blood flow to the liver
Which of the following is not a drug used to treat
alcoholism?
a. Naltrexone
b.Disulfiram
c. Acamprosate
d.Meperidine
Which of the following is not true of
pharmacological treatment of alcoholism?
a. Used to maintain abstinence
b.Used to treat symptoms from alcohol
c. Used to prevent relapse
d.Used in combination with behavioral therapy
Which of the following should not be used before
the patient has abstained for 12 hours?
a. Naltrexone
b.Disulfiram
c. Acamprosate
d.Meperidine
Which of the following may inhibit NMDA
receptors or stimulate GABA receptors?
a. Naltrexone
b.Disulfiram
c. Acamprosate
d.Meperidine
Which of the following blocks opioid receptors?
a. Naltrexone
b.Disulfiram
c. Acamprosate
d.Meperidine
For which of the following does the drug block
activation of dopamine neurons?
a. Naltrexone
b.Disulfiram
c. Acamprosate
d.Meperidine