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Methanol and Ethylene Glycol Intoxication
Methanol and Ethylene Glycol Intoxication

... The minimal lethal doses of methanol and ethylene glycol are not well established. Available information suggests that there is considerable person-to-person variability. There are several known factors that can affect this variability, including the degree of dilution of the methanol or ethylene gl ...
Modern Lacrimal Duct Surgery From the Ophthalmological Perspective
Modern Lacrimal Duct Surgery From the Ophthalmological Perspective

... can be distinguished from one another through careful history-taking and an ophthalmological examination. ...
Toxic Alcohol Ingestions: Clinical Features, Diagnosis, and
Toxic Alcohol Ingestions: Clinical Features, Diagnosis, and

... Jeffrey A. Kraut*† and Ira Kurtz†‡ *Medical and Research Services, UCLA Membrane Biology Laboratory, VHAGLA Healthcare System, and Division of Nephrology VHAGLA Healthcare System, †David Geffen School of Medicine, and ‡Division of Nephrology, UCLA Center for Health Sciences, Los Angeles, California ...
The Role of the Metabolic Acidosis in the Development of Chronic
The Role of the Metabolic Acidosis in the Development of Chronic

... digestion, circulation, excretion, and cellular metabolism. The acid-alkaline regulation systems are interrelated and work together to prevent acute or chronic changes in the body’s acid-base balance. What causes the body to be over acidic? The main persistent factors are: ...
Extended Spectrum Beta-lactamases: Definition, Classification and
Extended Spectrum Beta-lactamases: Definition, Classification and

... According to the Bush, Jacoby and Medeiros scheme, beta-lactamases are divided into four groups as shown in Table 1. The first scheme, introduced by Ambler (Ambler et al., 1991), which is also widely used, is shown in table 1 as well. Group I (Ambler Class C) beta-lactamases (also known as AmpC enzy ...
MBSAQIP Standards Manual - American College of Surgeons
MBSAQIP Standards Manual - American College of Surgeons

... program to incorporate new technology and improve a center’s ability to implement the standards. Metabolic and bariatric surgical procedures have been shown to reduce obesity, improve mortality, and decrease the health risks from chronic diseases, as evidenced in more than 20 years of peer-reviewed ...
Diagnosis and Management of Acid-Base Disorders
Diagnosis and Management of Acid-Base Disorders

... Pyroglutamic acidemia (5-oxoprolinemia) is a rare cause of high anion gap metabolic acidosis, which is associated with the use of medications like acetaminophen and flucloxacillin.8 This acidemia generally occurs in the setting of sepsis, liver failure, or renal failure.8 In the case of acetaminophe ...
Lactate versus non-lactate metabolic acidosis: a retrospective
Lactate versus non-lactate metabolic acidosis: a retrospective

... critically ill patients, metabolic acidosis can result from a variety of conditions [14]. Although the existing literature does not suggest a strong relationship between the type of acidosis and outcome, traditional methods of classifying and analyzing acid–base abnormalities have significant limita ...
Resources for Optimal Care of the Metabolic and Bariatric Surgery
Resources for Optimal Care of the Metabolic and Bariatric Surgery

... Optimal Care of the Metabolic and Bariatric Surgery Patient 2014, the MBSAQIP accredits inpatient and outpatient metabolic and bariatric surgery centers in the United States and Canada that have undergone an independent, voluntary, and rigorous peer evaluation in accordance with nationally recognize ...
Type B Lactic Acidosis Secondary to Thiamine
Type B Lactic Acidosis Secondary to Thiamine

... and L-carnitine were administered empirically to support mitochondrial metabolism. His lactate:pyruvate ratio before thiamine and L-carnitine administration was 20, which more strongly supports a PDH complex impairment rather than an electron transport chain impairment (eg, carnitine deficiency), in ...
Chronic Metabolic Acidosis Destroys Pancreas
Chronic Metabolic Acidosis Destroys Pancreas

Acid–Base
Acid–Base

... Finally serum potassium may be helpful in distinguishing causes of low SID acidosis. Hypokalemia (<3.5 mmol/L) is associated with ureteral diversion, diarrhea, proximal colostomy, ileostomy, proximal renal tubular acidosis (RTA), type I distal RTA, and parenteral nutrition. Hyperkalemia (>4.5 mmol/L ...
acid-base disturbances
acid-base disturbances

... Hypotonic hyponatremia most common scenario; true excess of free H2O relative to Na Hypertonic hyponatremia: excess of another effective osmole (eg, glc, mannitol) that draws H2O intravascularly; each 100 mg/dL ↑ glc >100 mg/dL → ↓ [Na] by 2.4 mEq/L Isotonic hyponatremia: rare lab artifact from hype ...
Chapter 52: Acid–Base Disorders
Chapter 52: Acid–Base Disorders

... Cellular metabolism results in the production of large quantities of hydrogen that need to be excreted to maintain acid–base balance. In addition, small amounts of acid and alkali are also presented to the body through the diet. The bulk of acid production is in the form of CO2, with the average adu ...
Metabolic acidosis: pathophysiology, diagnosis and management
Metabolic acidosis: pathophysiology, diagnosis and management

... Abstract | Metabolic acidosis is characterized by a primary reduction in serum bicarbonate (HCO 3–) concentration, a secondary decrease in the arterial partial pressure of carbon dioxide (PaCO 2) of ~1 mmHg for every 1 mmol/l fall in serum HCO3– concentration, and a reduction in blood pH. Acute form ...
Ethanol Pharmacokinetics in Neonates Secondary to Medication
Ethanol Pharmacokinetics in Neonates Secondary to Medication

... A total of 39 plasma samples from 15 neonates who were on ethanol containing medications were collected over the study period. Four neonates were exposed to phenobarbital and/or dexamethasone, while eleven neonates were exposed to buprenorphine alone or in combination with phenobarbital. Patients we ...
Ethanol Pharmacokinetics in Neonates Secondary to Medication
Ethanol Pharmacokinetics in Neonates Secondary to Medication

... A total of 39 plasma samples from 15 neonates who were on ethanol containing medications were collected over the study period. Four neonates were exposed to phenobarbital and/or dexamethasone, while eleven neonates were exposed to buprenorphine alone or in combination with phenobarbital. Patients we ...
Interpreting ABGs: The Basics
Interpreting ABGs: The Basics

... circulation. This “reclaimed” bicarbonate neutralizes much of the acid that is created when food is broken down in the body (NKUDIC, 2010). Since normal metabolism produces acid, the kidneys are continuously at work to maintain homeostasis by excreting metabolic acid. This is accomplished by several ...
ACID*BASE DISORDERS
ACID*BASE DISORDERS

... Determine and correct the cause, if possible, and replace HC03and potassium. Distal RTA may require an amount of HC03- replacement that roughly equals the daily production of hydrogen ion (50-100 mEq/ day). Some of the HC03- should be given as KHC03 to correct potassium losses as long as there is no ...
treatment guidelines for salicylate poisoning
treatment guidelines for salicylate poisoning

... 1.) Dose and urine pH: Salicylate elimination at therapeutic concentrations consists of predominantly of first-order hepatic elimination with only 10-20% of salicylate eliminated unchanged in the urine. In an overdose situation where metabolic pathways become saturated (zero order kinetic saturation ...
Metabolic Syndrome - Wild Iris Medical Education
Metabolic Syndrome - Wild Iris Medical Education

... diabetes usually shows up in older adults, but it can occur at any age. A distinguishing feature of type 2 diabetes is that, even when there is a normal amount of circulating insulin, body tissues do not take up glucose as readily as normal. This is called insulin resistance, a condition in which no ...
Physiological Approach to Assessment of Acid–Base Disturbances
Physiological Approach to Assessment of Acid–Base Disturbances

... life. Accurate and timely interpretation of an acid–base disorder can be lifesaving, but the establishment of a correct diagnosis may be challenging.1 The three major methods of quantifying acid–base disorders are the physiological approach, the base-excess approach, and the physicochemical approach ...
Physiological Approach to Assessment of Acid–Base
Physiological Approach to Assessment of Acid–Base

... life. Accurate and timely interpretation of an acid–base disorder can be lifesaving, but the establishment of a correct diagnosis may be challenging.1 The three major methods of quantifying acid–base disorders are the physiological approach, the base-excess approach, and the physicochemical approach ...
Physiological Approach to Assessment of Acid–Base Disturbances
Physiological Approach to Assessment of Acid–Base Disturbances

... life. Accurate and timely interpretation of an acid–base disorder can be lifesaving, but the establishment of a correct diagnosis may be challenging.1 The three major methods of quantifying acid–base disorders are the physiological approach, the base-excess approach, and the physicochemical approach ...
Liver phases 1 and 2 detoxification pathways
Liver phases 1 and 2 detoxification pathways

... The use of coffee in enemas for liver detoxification purposes is well known. It is a common herbalogical remedy that has been suggested by holistic and alternative medicine professionals for many years. The coffee enema has been used for many years to detoxify the liver. It is a low-volume enema tha ...
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