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Sinus rhythm with ventricular bigeminy due to digitalis toxicity. Ventricular premature complexes follow each sinus-conducted QRS at a fixed coupling interval. ST-segment depression and T wave inversion in the sinus-conducted beats is seen in V6; however, since each sinus-conducted beat is a postextrasystolic one, correct interpretation of ST-T abnormalities is difficult. The sinus rate is not measurable when ventricular bigeminy is present since consecutive sinus complexes are not present. Although ventricular bigeminy in this patient was associated with a toxic serum level of digoxin, this arrhythmia is not specific for digitalis intoxication. If a ventricular arrhythmia is due to digitalis toxicity, it is expected to disappear as the serum level of digitalis is lowered. Note the presence of P waves deforming the ST segments of the premature ventricular depolarizations (arrows); since the intervals Source: Heart Disease, Current Medical Diagnosis & Treatment 2017 between them and the preceding sinus P waves is not half the measured sinus cycle length, they are probably retrogradely conducted. (Reproduced, with Citation: PapadakisN,MA, McPhee SJ, Rabow MW. Current Medical Diagnosis &13th Treatment 2017; 2016 Available at: http://mhmedical.com/ permission, from Goldschlager Goldman MJ. Principles of Clinical Electrocardiography, ed. Originally published by Appleton & Lange. Copyright © Accessed: May 13, 2017 1989 by The McGraw-Hill Companies, Inc.) Copyright © 2017 McGraw-Hill Education. All rights reserved