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Discovery Partnerships with Academia: Non-confidential Proposal Please include non-confidential information only at this stage and keep to 1 page. If chosen, a confidentiality agreement will be executed to enable further discussions. Principal investigator(s) (Name, Title, Dept.) Project Title Therapeutic hypothesis Target defined Project status & enabling expertise Tractability Requirement for GSK contribution Clear and supportable hypothesis that modulation of target will produce an effect expected to be of therapeutic benefit. Please include any data linking pathway/target to human disease, such as genetic data. Specific drug target identified, with some understanding of type of pharmacology desired. Current project status. PI’s know-how, experience and expertise that is essential to progress the target which is not readily found elsewhere. A path to identification of a drug molecule can be defined. Target knowledge suggests that a drug-like molecule can be generated. GSK capability which will help progress the project. 2017 UTHealth Call for Proposals