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WHEN A SPERM MEETS AN EGG… TG/1.2.6 • Conception The ability to reproduce is necessary for the continuation of the human race. New life occurs when male and female sex cells unite at conception. The sex cells are needed to give birth to a new life. These sex cells are given the chance to fuse and form a new life during sexual intercourse. In mammals, such as human beings, conception begins with the act of intercourse. A women is most likely to conceive just after the time she ovulates – when an ovum has been released from the ovary. During intercourse, sperms from the man’s penis are deposited into the woman’s vagina. The semen which contains as many as 400 million sperms are deposited in the vagina. Most of the sperms leak out of the vagina again, but some begin to swim up in the vagina, making their way at a very rapid rate to the uterus and the fallopian tubes. As the time of ovulation, the mucus in the cervix is thinner than usual to allow the sperms to pass through more easily. As sperms reach the fallopian tubes where an ovum is likely to be found, one sperm may then join the ovum. This is commonly known as fertilization. Fertilization occurs in 5 stages as follows: − Penetration which occurs when the outer layer of the sperm unites with the membrane surrounding the ovum. − Union takes place where the contents of the sperm head have access to the ovum. − The sperm as a whole enters the ovum. − Activation where the ovum develops a reaction which prevents other sperms from gaining entry to it. − Fusion of nuclear materials from the two sex cells (ovum and sperm), after which cell division takes place. • Development of the fertilized ovum After fertilization, the fertilized ovum which has become a zygote travels from the fallopian tube to the uterus. As it travels, a series of events and changes begins to take place. First, the zygote undergoes cell division. It divides into 2 cells, then 4, then 8, then 16 and so on in a geometric progression. Three to 5 days after fertilization, the zygote reaches the uterus. Six to 7 days after fertilization, implantations occurs. The zygote that has become the blastocyst penetrates and sinks into the uterine lining or endometrium. The cell divides itself into ectoderm or outer skin which will cover the outer surface of the body and the endoderm or inner skin which will line the inner surface. Cells in the position of the ectoderm nearest the inner skin further multiply to form the skin and nervous system. The rest of the outer skin become amnion, the membrane which envelopes the embryo. Then the mesoderm is developed to form the connective tissues, bones, muscles, blood and blood vessels. Six to 7 days after fertilization, implantation occurs. The zygote which has become the blastocyst penetrates and sinks into the thickened uterine lining or endometrium. Sometimes, the blastocyst cannot travel from the fallopian tube to the uterus. Instead, it implants itself in the walls of the fallopian tube. In such rare cases, fertilization and implantation take place in the ovary. Whether the pregnancy is tubal, ovarian or abdominal, the general term used is ectopic pregnancy. At the moment of conception, the genes and chromosomes from the mother and father unite to form a unique individual with particular traits and characteristics. Occasionally, two ovum will be released at the same time. If this happens, it is possible for both to be fertilized and fraternal twins to be conceived. Identical twins are a result of the division of one fertilized ovum into two completely separate cells that then continue to develop into 2 babies. Siamese twins are extremely rare. These are identical twins that started to separate but some parts of the body remained joined. Surgeons may try to separate the two infants after birth. Sometimes both survive, sometimes one, sometimes neither.