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جامعة طنطا كلية الطب قسم عالج األورام و الطب النووي Faculty of Medicine, March 2017 Annual congress Clinical Oncology Department's Workshop Target Volume Definition in Radiation Oncology Thursday, 9th March. 2017 President of Workshop: Prof. Ashraf Fathi Barakat. Modulator of Workshop: Dr. Mohamed Fathy Sheta. [email protected] Chairpersons: Prof. Ashraf Barakat. Prof. Hesham Tawfek Prof. Hanan Shawky Prof. Samar Galal Principles of Planning and Target Delineation of prostate adenocarcinoma Dr. Fatma Gharib, MD. Lecturer of Clinical Oncology, Tanta University. Clinical Oncology& Nuclear Medicine. From – 10:12 A.M. E-mail: [email protected] INTRODUCTION: Prostate cancer is the second most common cancer in men worldwide and the sixth leading cause of male cancer death. Radiation therapy (external beam or brachytherapy), radical prostatectomy and active surveillance (in selected cases) are standard treatment options for localized prostate cancer. Long-term outcomes with recent external beam RT techniques that use high radiation doses and conformal treatment planning as well as neoadjuvant androgen deprivation therapy for higher-risk disease appear similar to surgery. 3D-conformal techniques and intensity modulated RT (IMRT) are the contemporary standard of care to treat localized prostate cancer. Conformal techniques allow higher doses to the target, while minimizing radiation to normal tissues. This permits a decrease in toxicity and improvement in therapeutic index. Principles of Planning and Target Delineation of Nasopharynx Lecturer. Rasha Abd-Alghany, MD. Lecturer of Clinical Oncology, Tanta University. Clinical Oncology& Nuclear Medicine. From 12.30– 2.30 P.M. E-mail: [email protected] INTRODUCTION: Intensity-modulated radiation therapy (IMRT) is the standard technique for definitive radiation therapy for nasopharyngeal cancer (NPC). In addition to thorough physical examination, adequate imaging studies should be obtained for diagnosis, staging, and planning. Unless contraindicated, all patients should undergo MRI of the nasopharynx and neck, preferably 3-mm slice thickness. A PET/CT scan is also preferable. However, including the PET-avid region only as gross tumor volume (GTV) is inadequate. The skull base, i.e., clivus, and the nerves are best seen on MRI. Marrow infiltration of disease is best seen on T1-weighted noncontrast MRI sequence. Fusion of the skull base portion of the MRI will aid in the delineation of the GTV. CT simulation with IV contrast should be performed to help guide the GTV target, particularly for the lymph nodes. plan is done, a thermoplastic mask to immobilize the head and neck including the shoulders will be preferable to only immobilizing the head and neck region.