Download PROBINORM

ARTLIFE company introduces a new
biologically active complex–
“PROBINORM”
The Innovative Bio-Technology
Micro Flora
The micro flora of the person possesses huge biological potential,
sufficient for that, to ensure the full protection of the organism and its
metabolic support.
The structure of microorganisms of a biofilm is constant at healthy
people and changes at pathological conditions. In norm
microbiocenosis intestines of the person consists on 85-98% from
bifid bacteria and lacto bacteria.
Infringement of microbiological balance in intestines of the person
serves a starting instant not only for progresses diseases of a
digestive tract, but also provides the foundation for a various
pathology of system character.
Function of Micro Flora
The normal micro flora carries out a number of the
important functions for ability to live and
participates in maintenance of a constancy of the
internal environment of an organism.
Protective
Exchange
Immune
Bifid Bacteria
• Actively participate in synthesis of vitamins and amino
acids
• speeds up digestion of fats, proteins and carbohydrates
break down tough cellulose
• stimulate synthesis of immunoglobulin's
• stimulate the activity of lymphoid apparatus
• Reduce permeability of fabric barriers to toxic products of
pathogenic organisms
Lacto Bacteria
• Produce antibacterial substances which
assist destruction of pathogenic bacteria
• Participate in the processes of digestion
• Produce many biologically active
substances
Factors influencing the change
in Micro Flora
The frequent and unjustified acceptance
of antibacterial drugs
Unhealthy Diet
Intoxication of various nature
Accommodation in environmentally
disadvantaged area.
Signs of Dysbacteriosis
Bowel Disorder/ Loose Motion
Flatulence (excessive formation of gas
in the gut)
Monotonous pain in a stomach (the
pulling and holding apart character,
usually amplifying in second half of
day)
A loud rumbling in stomach
Почему необходимо поддерживать
баланс микрофлоры
Appearance of dysbacteriosis
during the teenage period:
Подросткам
• Deviations at formation of reproductive
system
• Frequent fatigue and decreased
performance
• In allergic dermatitis treatment
• private colds
Почему необходимо поддерживать
баланс микрофлоры
Micro flora is involved in many
processes of the female body and
substantially defines the hormonal
status and genital function of the
woman.
Женщинам
The dysbacteriosis negatively
influences on micro biogenesis vaginal
that provokes progress of a candidacies
and increases susceptibility to infectious
diseases of the urinary system.
Why is it necessary to maintain the
balance of micro flora
Normal micro flora balance provides the
activation of immunoglobulin's (antibodies).
Natural levels of immunoglobulin's (G):
 Activates collagen synthesis
 Prevents dehydration of the skin
 Neutralizes toxins
Женщинам
Complex “Probinorm” is included in an antigen
line of cosmetics«Pro Biocosmetics», increasing
the efficiency of its uses.
Why is it necessary to maintain the
balance of micro flora
Middle-aged and older people should regularly
take pro biotic complexes, because:
 With age, the rate of intestinal micro flora is
beginning to deteriorate
 Reduced the protective functions of the micro flora
in countering the malignant new growths
 Decreased ability to metabolize cholesterol
Людям
старшего
возраста
 Disturbed immune status
 Accelerated aging processes
Improving the micro flora to normal, you
will get it within 24 hours:
 The whole list of vitamins-in total up to 50% daily needed
 Amino acid, including essential – 70%
 Enzyme: Digestive – 30% daily needed for person
 Energy Products– 60%
 Regulation of enzyme metabolism– to 60-70%
 Regulation of mineral metabolism– to 60-70%
Pro Biotic
Pro biotic (from Greek pro bio – far life) - products
containing high concentrations of mineral for the
body of the living forms of bacteria, that when
entering the intestine normalizes its ecosystem and
macro flora of the organism as a whole, heal and
prevent the development of pathological processes.
Complex “Probinorm” produced
with the use of innovative
biotechnology micro
encapsulation of bacteria
developed and patented by
experts of the
Art life company
ИННОВАЦИОННАЯ БИОТЕХНОЛОГИЯ
Live Bifida bacteria and lacto
bacteria bacterium
Acid gum
Bifida gum
Lacto gum
Highly tolerant strains bacteria
of different type consist in a thin
microcapsule, covered with a
hard shell of biopolymer
substances.
Latest research data of the pla
with the proven benefits of the
combined intake of these
bacteria.
INNOVATIVE BIOTECHNOLOGY
The bacteria are protected from the effects of
aggressive environment of the stomach
On a way of settling bacteria of intestines
are available a serious obstacle - the
sour environment of a stomach and
alkaline Wednesday of the duodenum.
The thin microcapsule covered by a
durable envelope from biopolymer
substances, protects bacteria from the
effects of environmental factors and
provides resistance to acidic
environment of the stomach contents.
Results - 100% populated beneficial bacteria reaches the
destination.
INNOVATIVE BIOTECHNOLOGY
Keep all useful properties of bacteria during
transportation to the place of destination
The core of the
microcapsules is made of
natural fibers, which are a
breeding ground for bacteria.
It keeps biological properties
of bacteria for a long period
of time, including
transportation to the place of
their active life activity.
INNOVATIVE BIOTECHNOLOGY
Vitamins and Pre biotic provide optimal conditions
for activation of beneficial bacteria
Cysteine
PABK
В2, В3
Inulin
crust
artichoke
Improving survival rate of microorganisms is the inclusion
complex of vitamins and pre
biotic substances in dosage,
optimized to the needs of microorganisms.
INNOVATIVE BIOTECHNOLOGY
Papain helps the best survival rate of bacteria and
intensify
The enzyme papain
provides complete
digestion in the gut
bacteria of settlement
period: complete
digestive reactions,
prevention of stagnation
of food residue,
improving the quality of
nutrient medium of
bacteria.
STATUS OF THE MICRO FLORA OF THE
BEFORE AND AFTER COMPLEX
“PROBINORM”
Before:
After:
Microbial balance
broken
Microbial balance
restored
STATUS OF THE MICRO FLORA OF THE
BEFORE AND AFTER COMPLEX
“PROBINORM”
Before:
After:
An active growth of
pathogenic flora.
Increases the growth of
beneficial bacteria.
STATUS OF THE MICRO FLORA OF THE
BEFORE AND AFTER COMPLEX
“PROBINORM”
Before:
Develops diarrhea and
intestinal tissue is
dehydrated.
After:
Water absorbed properly.
STATUS OF THE MICRO FLORA OF THE
BEFORE AND AFTER COMPLEX
“PROBINORM”
Before:
After:
Decreases the number of
antibodies that resist
pathogenic flora.
Immune globulins are
synthesized in good
quantity.
STATUS OF THE MICRO FLORA OF THE
BEFORE AND AFTER COMPLEX
“PROBINORM”
Before:
Decreases the number of
immune cells, absorbing the
pathogenic in micro-organisms.
After:
Immune cells in tone and
fully perform their functions.
THE CLINICAL RESEARCH
Testing was carried out in the year 2006 on
the basis of the Department of internal
medicine, the Faculty of advanced training
and post-graduate training of specialists
Sibgmu (Tomsk).
• Head – MD, Prof. Beloborodova E.i.
Clinical characteristic study:
• 30 volunteers with dysbacteriosis of the 2nd degree
(classification Kuvaevoj i.b., Ladozo K.s., 1998) caused by
taking antiboitic.
• AGE 40,5 + 0,7 Yrs.
• Prescription of daisies 3,0 + 0,2 Yr.
• Accompanying pathology: a metabolic syndrome (adiposity
I-II level, hypertonic illness of II level, hypercholesterolemia)
The clinical research
BIFIDA Bacteria*
Lacto Bacteria*
Normal
Till complex of
“Probinorm”
After Complex of “Probinorm”
106-108 104-105
>108
(р <0,05)
>108 <106
>108
(р <0,05)
* Microbes in 1 g of feces
Function of the complex "Probinorm" contributes to the growth
of beneficial microorganisms in the intestines, removing
obtained as a result of antibiotic treatment, intoxication, stress.
The clinical research
Total number of E. coli*
107-108 106-108 108
Escherichia coli with
weakly expressed
enzymatic properties*
до
10%
3050%
10%
(р <0,05)
Hemolyze
Escherichia coli*
до
10%
5080%
0%
(р <0,01)
Other conventionallypathogenic Enter
bacteria *
104
104-105 106-107
(р <0,05)
Function of Probinorm reduces the number of colonies of
conditionally pathogenic microorganisms, which are
activated when the wrong nutrition, malnutrition, infections
of the upper respiratory tract.
The clinical research
Staphylococcus*
0-1014
105-107 <102
(р <0,05)
The germs of proteus*
0-103 104-106 0-102
(р <0,05)
Mushrooms of the genus
Candia*
0-104 103-104 0
(р<0,01)
Clostridium*
0-105 103-105 <102
(р<0,05)
Function of Probinorm reduces the number of pathogenic
microorganisms in the intestine, assisting the general
improvement of an organism: the normal flora of intestines,
getting accustomed, completely displaces the fungi, protozoa
microorganisms and harmful bacteria.
Dynamics concentration of immunoglobulin's A, M, G,
under the influence of “Probinorm”
Immunoglobulin's
А (G/L)
М (G/L)
G (G/L)
100
0
1,9 + 0,22
Before complex of
“Probinorm”
After complex of
“Probinorm”
1,5 +0,97
2,3 + 0,31 1,7 +0,05*
14,0 + 0,67 12,0 +0,65*
* Reliability of the differences
before and after treatment
(* - p<0,05)
The normalization of intestinal micro flora is accompanied by
the removal from the body of harmful and Conducts to
strengthening immunity of an organism to what normalization of
a level of immunoglobulin's
А, М & G.
The use of particularly
effective:
After antibiotic therapy and exposure to toxins
When digestion dysfunctions, violations of food
intake
Reduce gastric acidity
Chronic diseases of digestive organs
Disease of the liver & belier tract
В12 and folic acid deficiency anemia
Advantages of the complex:
• Availability microencapsulated form of bacteria
(100% delivery of the localization)
Availability of nutrients in conjunction with the
bacteria (optimal environment for the formation
of life)
• The presence of growth factors for bacteria
(stimulation of reproduction and the most rapid
microbial balance correction)
• Availability pelleted papain digestion supporting
intraenteric (prevention of microbial colonies
from the toxic action of harmful metabolites).
Thanks For Attention!