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The Urinary System Kidney The urinary system • The urinary system provides temporary storage reservoirs for urine or serve as transportation channels • The organs involved in the urinary system are: - Kidney - Ureter - Bladder - Urethra Kidneys • Locations: - The kidneys extend from T12 to L3 - Because it is crowded by the liver, the right kidney is positioned slight lower than the left • An adult kidney is about the size of a large bar of soap Kidney Structure • A fibrous, transparent renal capsule encloses each kidney: - In a living person, a fatty mass, the adipose capsule, surrounds each kidney and helps hold it in place against the muscles of the trunk wall Kidney Structure • The kidney has 3 distinct regions: 1. Renal cortex: The outer region, light in color 2. Renal medulla: Deep to the cortex, darker reddish-brown area - It is made of many triangular regions with a striped appearance, the medullary pyramids - The pyramids are separated by extensions of cortical tissue, the renal columns Kidney Structure 3. Renal pelvis: medial to the cortex, a basin-like cavity - Extensions of the pelvis, calyces, form cup shaped areas that enclose the tips of the pyramid Blood Supply • The kidneys continuously cleanse the blood and adjust its composition: - Approximately ¼ of the total blood supply of the body passes through the kidneys each minute Renal Arteries • Renal Arteries (from large to small): - Renal artery - Segmental artery - Lobar artery - Interlobar artery - Arcuate artery - Interlobular artery Renal Veins • Venous blood draining from the kidney flows through veins that trace the pathway of the arterial supply but in a reverse direction: - Interlobular veins arcuate viens interlobar veins renal veins - There are no lobar or segmental veins Nephrons • Nephrons: the structural and functional units of the kidneys and are responsible for forming the urine product - Each nephron consists of two main structures: 1. Glomerulus: knot of capillaries 2. Renal tubule Tubules • Bowman’s capsule: the closed end of the renal tubule that is enlarged and cup-shaped and completely surrounds the glomerulus • Tubules (from bowman’s capsule to renal pelvis): Proximal convoluted tubule Loop and Henle Distal convoluted tubule Collecting ducts Tubules • The lumen surfaces of the tubule cells in the proximal convoluted tubules are covered with dense microvilli • Microvilli also occur on the tubule cells in other parts of the tubule but in much reduced numbers Types of nephrons • Most nephrons are called cortical nephrons because they are located almost entirely within the cortex • Some nephrons are called juxtamedullary (juxta- nearby) nephrons because they are situated close to the cortexmedulla junction and their loops of Henle dip deep into the medulla Capillaries • Each and every nephron is associated with 2 capillary beds: - The glomerulus - Peritubular capillaries (peri- around) • The glomerulus is both fed and drained by arterioles: - The afferent arteriole: feeder vessel - The effector arteriole: receives blood that has passed through the glomerulus Capillaries • The peritubular capillaries: - Arise from the efferent arteriole that drains the glomerulus - Drain into interlobular veins leaving the cortex Urine Formation • Urine formation is a result of 3 processes: 1. Filtration 2. Reabsorption 3. Secretion • Filtration: - non-selective, passive process - Water and solutes smaller than proteins are forced through the capillary walls and pores of the glomerular capsule into the renal tubule Urine Formation • Reabsorption: - Water, glucose, amino acids and needed ions are transported out of the filtrate into the tubule cells and then enter the capillary blood Urine Formation • Secretion: - It is essentially reabsorption in reverse - H+ , K+, and breakdown product of the body are removed from the peritubular capillaries to the tubules