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Substance Related Disorders Substance Abuse & Substance Dependence Substance~Related Disorders Like other psychiatric disorders, the criteria for diagnosis and associated features can be complex, and understanding substance~related disorders requires a great deal of scholarly interaction and clinical experience. Diagnoses associated with class of substances Alcohol Amphetamines Caffeine Cannabis Cocaine Hallucinogens Inhalants Nicotine Opioids Phencyclidine Sedatives, hypnotics, or anxiolytics Polysubstance Features of Substance Dependence The essential feature of Substance Dependence is a cluster of cognitive, behavioral, and physiological symptoms indicating that the individual continues use of the substance despite significant substancerelated problems. Although not specifically listed as a criterion item, “craving” is likely to be experienced by most (if not all) individuals with Substance Dependence. Dependence is defined as a cluster of three or more of the symptoms listed on the following page occurring at any time in the same 12-month period. Criteria for Substance Dependence Tolerance, as defined by either of the following: a) a need for markedly increased amounts of the substance to achieve intoxication or desired effect; b) markedly diminished effect with continued use of the same amount of the substance. Withdrawal, as manifested by either of the following: a) the characteristic withdrawal syndrome for the substance; b) the same (or closely related) substance is taken to relieve or avoid withdrawal symptoms Criteria cont’d The substance is often taken in larger amounts or over a longer period than was intended There is a persistent desire or unsuccessful efforts to cut down or control substance use A great deal of time is spent in activities necessary to obtain the substance (e.g., visiting multiple doctors or driving long distances), use the substance (e.g., chain-smoking), or recover from its effects Important social, occupational, or recreational activities are given up or reduced because of substance use The substance use is continued despite knowledge of having a persistent or recurrent physical or psychological problem that is likely to have been caused or exacerbated by the substance (e.g., current cocaine use despite recognition of cocaineinduced depression, or continued drinking despite recognition that an ulcer was made worse by alcohol consumption. Criteria for Substance Abuse A maladaptive pattern of substance use leading to clinically significant impairment or distress, as manifested by one (or more of the following, occurring within a 12-month period: Recurrent substance use resulting in a failure to fulfill major role obligations at work, school, or home (e.g., repeated absences or poor work performance related to substance use; substancerelated absences, suspensions, or expulsions from school; neglect of children or household) Criteria for substance abuse cont’d Recurrent substance use in situations in which it is physically hazardous (e.g., driving an automobile or operating a machine when impaired by substance use) Recurrent substance-related legal problems (e.g., arrests for substance-related disorderly conduct) Continued substance use despite having persistent or recurrent social or interpersonal problems caused or exacerbated by the effects of the substance (e.g., arguments with spouse about consequences of intoxication, physical fights) Other features Wide cultural variations in attitudes toward substance consumption. Some cultures widely-accept substance consumption and others completely forbid it Individuals between 18-24 years have relatively high prevalence rates for the use of virtually every substance, including alcohol. Dependence can occur at any age, but typically has its initial onset for most drugs of abuse in the 20s, 30s, and 40s. When a substance-related disorder other than Intoxication begins in early adolescence, it is often associated with Conduct Disorder and failure to complete school. More males than females, but depends on the class of substance being abused.