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Emerging Infections - Potential Plagues Missing Microbes: How the Overuse of Antibiotics Is Fueling Our Modern Plagues Martin J Blaser 2014 4.6 stars/296 reviews 12 copies in the library Tracing one scientist’s journey toward understanding the crucial importance of the microbiome, this revolutionary book will take readers to the forefront of trail-blazing research while revealing the damage that overuse of antibiotics is doing to our health: contributing to the rise of obesity, asthma, diabetes, and certain forms of cancer. In Missing Microbes, Dr. Martin Blaser invites us into the wilds of the human microbiome where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now, this invisible eden is being irrevocably damaged by some of our most revered medical advances—antibiotics—threatening the extinction of our irreplaceable microbes with terrible health consequences. Taking us into both the lab and deep into the fields where these troubling effects can be witnessed firsthand, Blaser not only provides cutting edge evidence for the adverse effects of antibiotics, he tells us what we can do to avoid even more catastrophic health problems in the future. Good Germs, Bad Germs: Health and Survival in a Bacterial World Jessica Snyder Sachs 2008 4.7 stars/37 reviews 6 copies in the library Public sanitation and antibiotic drugs have brought about historic increases in the human life span; they have also unintentionally produced new health crises by disrupting the intimate, age-old balance between humans and the microorganisms that inhabit our bodies and our environment. As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs tells the story of what went terribly wrong in our war on germs. It also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that to a day when we may replace antibacterial drugs and cleansers with bacterial ones. Spillover: Animal Infections and the Next Human Pandemic David Quammen 2013 4.6 stars/297 reviews 7 copies in the library A New York Times Notable Book of the Year, a Scientific American Best Book of the Year, and a Finalist for the National Book Critics Circle Award. Ebola, SARS, Hendra, AIDS, and countless other deadly viruses all have one thing in common: the bugs that transmit these diseases all originate in wild animals and pass to humans by a process called spillover. In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be? The End of Plagues: the Global Battle Against Infectious Disease John Rhodes 2013 4.6 stars/5 reviews 6 copies in the library At the turn of the twentieth century, smallpox claimed the lives of two million people per year. By 1979, the disease had been eradicated and victory was declared across the globe. Yet the story of smallpox remains the exception, as today a host of deadly contagions, from polio to AIDS, continue to threaten human health around the world. Spanning three centuries, The End of Plagues weaves together the discovery of vaccination, the birth and growth of immunology, and the fight to eradicate the world's most feared diseases. From Edward Jenner's discovery of vaccination in 1796, to the early nineteenth-century foundling voyages in which chains of orphans, vaccinated one by one, were sent to colonies around the globe, to the development of polio vaccines and the stockpiling of smallpox as a biological weapon in the Cold War, world-renown immunologist John Rhodes charts our fight against these plagues, and shows how vaccinations gave humanity the upper hand. Today, aid groups including the Bill and Melinda Gates Foundation and the World Health Organization have made the eradication of polio a priority, and Rhodes takes us behind the scenes to witness how soon we may be celebrating the eradication of polio. 1 Emerging Infections - Potential Plagues The Viral Storm: The Dawn of a New Pandemic Age Nathan Wolfe 2012 4.1 stars/56 reviews 2 copies in the library In The Viral Storm, award-winning biologist Nathan Wolfe tells the story of how viruses and human beings have evolved side by side through history; how deadly viruses like HIV, swine flu, and bird flu almost wiped us out in the past; and why modern life has made our species vulnerable to the threat of a global pandemic. He takes readers along on his groundbreaking and often dangerous research trips to reveal the surprising origins of the most deadly diseases and to explain the role that viruses have played in human evolution. In a world where each new outbreak seems worse than the one before, Wolfe points the way forward, as new technologies are brought to bear to neutralize these viruses and even harness their power for the good of humanity. His provocative vision of the future will change the way we think about viruses, and perhaps remove a potential threat to humanity's survival. The New Killer Disease: How the Alarming Evolution of Mutant Germs Threatens Us All Elinor Levy 2003 5.0 stars/4 reviews 3 copies in the library The strange new disease SARS erupted apparently out of nowhere and has spread at an astonishing rate. Scary as SARS itself is, the disease is also a warning of many possible such outbreaks to come. Featuring the disturbing story of SARS—where it came from, what it is, and how to protect yourself from it—as well as those of many other recently evolved deadly scourges, the book is a shocking call to arms. All around us—in our homes, workplaces, and public spaces—bacteria and viruses are evolving at a feverish rate, and our best defenses against them are in danger of being overwhelmed. The threat posed by emerging infectious diseases is as formidable as any challenge the human race has ever faced, and the evolutionary scales may be tipping in favor of the microbes. In this book, a respected immunologist and a veteran science author introduce the vital facts the public must know about the astonishing range of killer microbes we are up against. From the SARS and West Nile viruses to mad cow and Ebola, thirty new deadly diseases have arisen since the 1970s, and twenty old scourges, such as plague and cholera, are reemerging. But the FDA only recently approved the first new type of antibiotic in thirty-four years, and vaccines for many of the most lethal viruses are a long way from development. In addition, researchers have only lately discovered that bacteria have been swapping resistance genes—genes that help them evade the drugs meant to kill them—and are evolving new mechanisms to fight off even our best drugs at a startling pace. A Planet of Viruses Carl Zimmer 2012 4.1 stars/73 reviews 4 copies in the library Viruses are the smallest living things known to science, yet they hold the entire planet in their sway. We are most familiar with the viruses that give us colds or the flu, but viruses also cause a vast range of other diseases, including one disorder that makes people sprout branch-like growths as if they were trees. Viruses have been a part of our lives for so long, in fact, that we are actually part virus: the human genome contains more DNA from viruses than our own genes. Meanwhile, scientists are discovering viruses everywhere they look: in the soil, in the ocean, even in caves miles underground. This fascinating book explores the hidden world of viruses—a world that we all inhabit. Here Carl Zimmer, popular science writer and author of Discover magazine’s award-winning blog The Loom, presents the latest research on how viruses hold sway over our lives and our biosphere, how viruses helped give rise to the first life-forms, how viruses are producing new diseases, how we can harness viruses for our own ends, and how viruses will continue to control our fate for years to come. In this eye-opening tour of the frontiers of biology, where scientists are expanding our understanding of life as we know it, we learn that some treatments for the common cold do more harm than good; that the world’s oceans are home to an astonishing number of viruses; and that the evolution of HIV is now in overdrive, spawning more mutated strains than we care to imagine. 2 Emerging Infections - Potential Plagues Betrayal of Trust: The Collapse of Global Public Health Laurie Garrett 2001 4.2 stars/52 reviews 3 copies in the library In this meticulously researched and ultimately explosive new book by the Pulitzer Prize-winning author of the New York Times bestseller The Coming Plague, Laurie Garrett takes on perhaps the most crucial global issue of our time. She asks: is our collective health in a state of decline? If so, how dire is this crisis and has the public health system itself contributed to it? Using riveting detail and finely-honed storytelling, Garrett exposes the underbelly of the world's globalization to find out if it can still be assumed that government can and will protect the people's health, or if that trust has been irrevocably broken. CLASSIC BOOKS (over 15 years old) The Coming Plague: Newly Emerging Disease Laurie Garrett 1995 4.5 stars/125 reviews 3 copies in the library Unpurified drinking water. Improper use of antibiotics. Local warfare. Massive refugee migration. Changing social and environmental conditions around the world have fostered the spread of new and potentially devastating viruses and diseases—HIV, Lassa, Ebola, and others. Laurie Garrett takes you on a fifty-year journey through the world's battles with microbes and examines the worldwide conditions that have culminated in recurrent outbreaks of newly discovered diseases, epidemics of diseases migrating to new areas, and mutated old diseases that are no longer curable. She argues that it is not too late to take action to prevent the further onslaught of viruses and microbes, and offers possible solutions for a healthier future. The Hot Zone Richard Preston 1995 4.5 stars/1,036 reviews 12 copies in the library The bestselling landmark account of the first emergence of the Ebola virus. A highly infectious, deadly virus from the central African rain forest suddenly appears in the suburbs of Washington, D.C. There is no cure. In a few days 90 percent of its victims are dead. A secret military SWAT team of soldiers and scientists is mobilized to stop the outbreak of this exotic "hot" virus. The Hot Zone tells this dramatic story, giving a hair-raising account of the appearance of rare and lethal viruses and their "crashes" into the human race. Shocking, frightening, and impossible to ignore, The Hot Zone proves that truth really is scarier than fiction. 3