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Endocrine System Hormones & Homeostasis AP Biology 2006-2007 Homeostasis Homeostasis maintaining internal balance in the body organism must keep internal conditions stable even if environment changes also called “dynamic equilibrium” example: body temperature humans: too cold = shiver too warm = sweat Regents Biology lizard: too cold = bask in sun too warm = hide in shade Regulation How we maintain homeostasis nervous system nerve signals control body functions endocrine system Regents Biology hormones chemical signals control body functions Nervous System Control Feedback Controlling Body Temperature nerve signals brain sweat high body temperature low brain constricts surface shiver blood vessels Regents Biology nerve signals dilates surface blood vessels Hormones Why are hormones needed? chemical messages from one body part to cells in other parts of body communication needed to coordinate whole body maintaining homeostasis Regents Biology growth hormones Endocrine System Endocrine system releases hormones glands which secrete (release) chemical signals into blood chemicals cause changes in other parts of body growth hormones sex hormones response hormones metabolism hormones and more…. Regents Biology Responding to hormones Lock and key system hormone fits receptor on “target” cell target cell secreting cell Regents Biology can’t read signal nontarget cells can’t read signal Glands Pineal Pituitary insulin, glucagon Ovary adrenaline Pancreas thyroxine Adrenal many hormones: master gland Thyroid melatonin estrogen Testes testosterone Regents Biology Feedback Maintaining homeostasis hormone 1 lowers body condition gland high specific body condition low raises body condition Regents Biology gland hormone 2 Negative Feedback Response to changed body condition if body is high or low from normal level signal tells body to make changes that will bring body back to normal level once body is back to normal level, signal is turned off gland hormone 1 lowers body condition high Regents Biology specific body condition Endocrine System Control Regulation of Blood Sugar Feedback insulin liver stores sugar body cells take up sugar from blood pancreas high liver blood sugar level (90mg/100ml) low triggers hunger Regents Biology liver releases sugar liver pancreas glucagon reduces appetite Everyone’s doing it, so Ask Questions!! AP Biology 2006-2007 Sex & Growth Hormones Large scale body changes how do they work turn genes on start new processes in the body by turning genes on that were lying “dormant” Regents Biology Pituitary gland hormones Sex & reproductive hormones FSH LH luteinizing hormone stimulates ovaries & testes prepares uterus for fertilized egg oxytocin follicle stimulating hormone stimulates egg & sperm production stimulates childbirth contractions releases milk in nursing mothers prolactin milk production in nursing mothers Regents Biology hormones hormones Reproductive hormones Testosterone from testes sperm production & secondary sexual characteristics Estrogen from ovaries egg production, preparing uterus for fertilized egg & secondary sexual characteristics Regents Biology Male reproductive system Sperm production over 100 million produced per day! Regents Biology ~2.5 million released per drop! seminiferous tubule sperm spermatocytes Regents Biology Male reproductive system Testes & epididymis sperm production & maturation Glands seminal vesicles, prostate, bulbourethal produce seminal fluid Regents Biology nutrient-rich Male reproductive system Testicles Scrotum where sperm mature Vas deferens sac that holds testicles outside of body Epididymis produces sperm & hormones tubes for sperm to travel from testes to penis Prostate, seminal vesicles, Cowper’s (bulbourethal) glands nutrient rich fluid to feed & protect sperm Regents Biology Female reproductive system Regents Biology Female reproductive system Ovaries Uterus tubes for eggs to travel from ovaries to uterus Cervix nurtures fetus; lining builds up each month Fallopian tubes produces eggs & hormones opening to uterus, dilates 10 cm for birthing baby Vagina birth canal for birthing baby Regents Biology Female reproductive system Regents Biology Egg maturation in ovary releases progesterone maintains uterus lining Regents Biology produces estrogen LH Menstrual cycle Controlled by interaction of 4 hormones egg development FSH & LH estrogen progesterone FSH ovulation = egg release corpus luteum estrogen progesterone lining of uterus Regents Biology days 0 7 14 21 28 Feedback Female reproductive cycle egg matures & is released (ovulation) estrogen builds up uterus lining corpus luteum ovary progesterone FSH & LH maintains uterus lining fertilized egg (zygote) HCG yes pituitary gland pregnancy GnRH Regents Biology hypothalamus no corpus luteum breaks down progesterone drops menstruation corpus luteum progesterone maintains uterus lining Female hormones FSH & LH Estrogen released from pituitary stimulates egg development & hormone release peak release = release of egg (ovulation) released from ovary cells around developing egg stimulates growth of lining of uterus decreasing levels causes menstruation Progesterone released from “corpus luteum” in ovaries cells that used to take care of developing egg stimulates blood supply to lining of uterus decreasing levels causes menstruation Regents Biology Fertilization Regents Biology Any Questions?? AP Biology 2006-2007 What do they do? Maintain homeostasis blood sugar level temperature control Start a new process growth fetal development sexual development Regents Biology Body Temperature Negative Feedback Negative feedback every time body is high or low from normal level a signal tells the body to make changes that will bring body back body temperature control of blood sugar Regents Biology Regulation by chemical messengers Neurotransmitters released by neurons Hormones release by endocrine glands endocrine gland neurotransmitter axon hormone carried by blood receptor proteins Regents Biology receptor proteins target cell Body Regulation Nervous system & Endocrine system work together hypothalamus “master nerve control center” receives information from nerves around body about internal conditions communicates with pituitary gland “master gland” releases many hormones hormones sexual development, growth, Regents Biology milk production, pain-relief hormones