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Which drugs do you take when you are ill? Why? Antibiotics Antibiotics L.O: To understand how antibiotics work and the advantages and disadvantages associated with them. Defence against disease quiz Fleming video How do doctors treat bacterial, fungal and viral infections? • Often drugs relieve the symptoms of a disease but do not kill the pathogens e.g.____________ • Antibiotics are chemicals which kill bacteria and fungi e.g.__________ • Antibiotics do not kill _______ • Antibiotics do not damage your own cells • If used too frequently bacteria can become resistant to _____________ • It is very difficult to find drugs for viruses because they reproduce rapidly and inside ________, it is difficult to develop drugs that kill viruses without damaging your cells Investigating the growth of bacteria. Predict which plate will have the biggest growth bacteria and explain why. Using discs on agar covered with bacteria : this technique is used in hospitals on samples of urine blood and stools to work out which antibiotic to use • Which antibiotic is the best? • Which antibiotic are the bacteria most resistant to? • What is the difference between antiseptics and antibiotics A B C D E Antibiotics Advantages • Cures a lot of diseases • Usually relieves symptoms in a few days • Reduces deaths from diseases Disadvantages • Resistant bacteria can develop • Diseases become more difficult to treat • Not taking the full course causes more resistant bacteria to survive Results A. Collect your agar plates. B. Examine the agar surface, looking for clear areas around the discs (where the bacteria have been killed). Measure the radius of any clear areas. C. Design and draw up a table in which to record your results, and also those from the rest of the class. D. You may wish to determine the mean results for the class. Conclusion • Hypothesis: ‘the survival and growth of the micro-organisms depends on the type of antibiotic used’ • Do your results support the hypothesis? 1 mark • Which antibiotic was best at killing E.Coli? Which antibiotic was best at killing M.Luteus? • Were the results repeatable or reproducible? • 2 marks 2 marks Context If you were working in a hospital laboratory, and you had just carried out this test on bacteria isolated from sick patients, would you always choose the antibiotic that gave the biggest inhibition zone? Are there any other factors you would need to consider?