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ATP: The Molecular Source of Energy US Patent # 8,344,032 B2 By Kevin J. Meehan Lac, M.S., Dipl of Ac, NCCAOM, NCCA Learn what leading researchers, doctors and health conscious professional athletes have already discovered: ATP is the molecular source of Energy! Living cells utilize adenosine triphosphate (ATP) for energy. Thus, ATP is commonly referred to as the ‘molecular source of energy’ and its production is critical to a vast array of metabolic and physiological functions. The human body only stores a minimal amount of ATP (maybe only six seconds worth when we are in seated position) and one of our metabolisms primary objective is to produce an adequate and steady supply of ATP as needed so that our living cells can respond to the multiple amounts of stresses we put on our systems from walking to strenuous exercise. ATP molecules are generated by utilizing several metabolic fuels, from carbohydrates to fats to lactic acid. It is now being recognized by many researchers that physiological performance and a variety of diseases may be linked to our inability to generate adequate amounts of ATP. The current consensus among scientists regarding how many moles (molecules) of ATP are generated from one mole of glucose (fuel source) in an aerobic scenario fluctuates from 38 to 31. Once the system enters the anaerobic state, the moles of ATP produced by one mole of glucose drops by at least ten times (one mole of glucose generates 3 moles of ATP). These anaerobic conditions occur in not only exercise but also situations of disease, neglect of health and emotional stress. The idea of measuring ATP production is fairly new and many researchers are still hesitant to suggest that these numbers are a real biological indicator of good health or fitness. What is clear is that a dramatic reduction in energy production can have a profound effect upon our body’s physiological functions and performance. Our body mostly produces ATP by a process known the Krebs cycle. This cycle is a series of reactions dependent on 7 enzymes in the mitochondria and consists of a multitude of reactions required for converting most of our fat and carbohydrate energy to ATP and heat. In a step wise fashion, these nutrients are then broken down to yield carbon dioxide (CO2). This reaction process is coupled with the regeneration of ATP. Simply stated, the Krebs cycle is used to oxidize nutrients, including lactate, to CO2 and in the process, produces energy for our cells. Many are familiar with lactic acid (lactate) and its negative impact upon our muscles after exercise. While lactate is an important byproduct of glycogen metabolism, in many ways it is a deterrent to health and performance if an overabundance exists within our tissues. This can occur if the Krebs cycle is underactive in its series of reactions (transformations) which result in the reduction of generating ATP. If the enzyme’s catalytic activity within the Krebs cycle and the respiratory chain are compromised in any way, the series of reactions which generate ATP and utilize the metabolic fuel sources to do so (fats, lactic acid, carbohydrates, etc.) become reduced. Consequently, this can compromise performance and may lead to a vast array of diseases and health issues. These enzymes require specific substrates in order to function at the optimal peak of efficiency. Current research is suggesting that optimizing the substrates required for the Krebs cycle and ATP production may have a direct impact on how many moles of ATP are produced per unit of a given mole of fuel. This revolutionary is all natural – the formulation is based on recent research in ATP production and innovations in biotechnology and nutrition. This patent-pending formula is based on supporting the Krebs cycle’s series of reactions by enhancing the activity of the seven enzymes in the mitochondria. By maximizing the enzyme’s catalytic activity, the potential of synthesizing Adenosine Triphosphate is also maximized. This provides your cells with more energy and allows the body to burn lactic acid more efficiently which in turn leads to better recovery after strenuous exercise. Bio Factor’s ATP formulation differs from most all other “energy formulations” in that it doesn’t rely on thermogenic or stimulatory substances as its basis. These compounds, such as ephedra and caffeine or glucose elevating compounds such as creatine, can have long term deleterious effects on the homeostasis of the body. Creatine, as an example, produces formaldehyde when taken as a supplemental adjunct. Ephedra or equivalent stimulatory substances can be adaptive; meaning that the body will eventually rely on these substances to parallel the cortisol “rush” experienced as a result of taking these products. This in turn could lead to a hyperglycemic condition. Kevin J. Meehan Meehan Formulations, LLC Teton Valley Health Clinic Jackson, WY USA 307-734-8044 Available in powder drink mix and an energy shot!