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Name: ________________________________ Enzyme Activity: Pepsin and Trypsin In the Diagram to the left, you will see a basic drawing of the human digestive system. One of the many functions enzymes perform in the body is digestion. Pepsin and Trypsin are both types of digestive enzymes. However each works in a different organ of the digestive system. Pepsin is secreted by the stomach and Trypsin is secreted by the small intestines. Below is a graph of the rates of reaction of both Pepsin and Trypsin in different pH conditions for the reactions they carry out. Use the picture to the left and the graph below to complete the questions on the back. 1. In what range of pH does pepsin function? _________ What is the Optimum pH for pepsin? ______ 2. In what range of pH does trypsin function? _________ What is the optimum pH for trypsin? ______ 3. What is the normal pH for the stomach? ______ What is the normal pH for the small intestines? ______ 4. Using your answers from questions 1 - 3, explain what must happen to the solution the food is in as it moves from the stomach to the small intestine and why that has to happen in order for digestion to occur correctly. (Use COMPLETE Sentences) ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ 5. Could Trypsin work in the stomach? _____ Why do you think that? _______________ ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ 6. Could Pepsin work in the small intestines? _____ Why do you think that? ___________ ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ 7. Homeostasis is one of the 7 characteristics of life and it states that all living organisms must maintain a constant internal environment. Knowing this and what you have just learned from this worksheet explain how it can be said that humans maintain homeostasis even though pH is not constant throughout the body. ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________