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EXTRACTION DECISION-MAKNG IN CLASS I MALOCCLUSIONS: A SURVEY IDENTIFYING VALUES FOR DEFINITE EXTRACTION AND NON-EXTRACTION THERAPY Samuel I. Gentry, D.D.S. An Abstract Presented to the Faculty of the Graduate School of Saint Louis University in Partial Fulfillment of the Requirements for the Degree of Master of Science in Dentistry 2009 Abstract Purpose: It was the purpose of this study to test the opinion of orthodontists as to the values they hold that direct the need for extractions based on individual measurements. Methods: A survey of 18 questions pertaining to 9 diagnostic measurements was sent to 10,315 AAO members. Respondents were also asked to indicate his/her gender, years of experience in orthodontics, and general orthodontic technique. surveys were completed. Results: A total of 992 Ranges of responses representing the middle 80% of respondents abutted without overlap for crowding, L1-APog, midline deviation, and FMA. Similar ranges overlapped for curve of Spee and Bolton discrepancy while there appeared ranges of values separating the ranges for B-line, IMPA, and nasolabial angle. Practitioners with fewer than 5 years of experience responded differently from those with more years of experience for 8 of 9 nonextraction measurements. Conclusions: There was an apparent shift toward more protrusive teeth and lips as acceptable treatment goals. Experience plays a significant role in the decision to treat a case non-extraction making the decision to extract more clear-cut. 1 EXTRACTION DECISION-MAKNG IN CLASS I MALOCCLUSIONS: A SURVEY IDENTIFYING VALUES FOR DEFINITE EXTRACTION AND NON-EXTRACTION THERAPY Samuel I. Gentry, D.D.S. A Thesis Presented to the Faculty of the Graduate School of Saint Louis University in Partial Fulfillment of the Requirements for the Degree of Master of Science in Dentistry 2009 COMMITTEE IN CHARGE OF CANDIDACY: Professor Eustaquio A. Araujo Chairperson and Advisor Professor Rolf G. Behrents Adjunct Professor Peter H. Buschang Professor Gus Sotiropoulous i DEDICATION This thesis is dedicated to my wife Stephanie, who did not move home without me; to my parents for assuring me that an education is the one investment in which you control the returns; and to Dr. Stephen L. Wallace, whose handshake was as meaningful as any legal document. ii ACKNOWLEDGEMENTS I would like to thank the following individuals for their contributions to this thesis: Dr. Araujo, an old soul, for getting this project up and running, and for his constant encouragement, Dr. Behrents for helping me understand the importance of attention to detail, Dr. Buschang for his dedication to the profession which poured over into my research experience, Dan Kilfoy for his expertise and willingness to help. iii TABLE OF CONTENTS List of Tables.............................................v List of Figures...........................................vi CHAPTER 1: INTRODUCTION...................................1 CHAPTER 2: REVIEW OF THE LITERATURE Orthodontic Extractions ........................3 History ...................................3 Extraction Trends .........................7 Extraction Effects ........................7 The Borderline Patient .........................9 Clinical Classification ..................10 Cephalometric Classification .............14 Nonextraction Treatment Options ..........18 Extraction Treatment Options .............21 Decision-Making Aids .....................22 Summary and Statement of Thesis ...............23 References ....................................24 JOURNAL ARTICLE Abstract ......................................31 Introduction ..................................33 Materials and Methods .........................35 Results .......................................39 Sex differences ..........................44 Experience ...............................44 Bracket Prescription .....................47 Discussion ....................................49 Conclusions ...................................53 References ....................................54 CHAPTER 3: Appendix A (copy of survey)...............................57 Appendix B (distribution charts for all measurements).....65 Vita Auctoris.............................................70 iv LIST OF TABLES Table 3.1: Survey measurements with respective answer choices ......................................35 Table 3.2: Descriptive statistics of completed surveys...39 Table 3.3: Differences in extraction and non-extraction treatment decisions between female and male respondents ...................................45 Table 3.4: Summary of one-way ANOVAs of experience differences in extraction and non-extraction variables .....................................46 Table 3.5: Results of Bonferroni post hoc tests comparing the different levels of experience for extraction and non-extraction variables .......47 Table 3.6: Summary of independent t-tests of bracket prescription differences in extraction and nonextraction variables ..........................48 v LIST OF FIGURES Figure 2.1: Extraction rates of the 20th century..........8 Figure 3.1: Example question utilizing visual aid........36 Figure 3.2: Survey modes with 10th and 90th percentiles for individual measurements..................40 Figure 3.3: Distribution of responses to millimetric values of crowding ..........................40 Figure 3.4: Distribution of IMPA responses...............44 Figure A.1: Distribution of responses for crowding.......65 Figure A.2: Distribution of responses for curve of Spee .............................................65 Figure A.3: Distribution of responses for Bolton discrepancy .................................66 Figure A.4: Distribution of responses for FMA............66 Figure A.5: Distribution of responses for IMPA...........67 Figure A.6: Distribution of responses for L1-APog........67 Figure A.7: Distribution of responses for B-line.........68 Figure A.8: Distribution of responses for nasolabial angle. .............................................68 Figure A.9: Distribution of responses for midline deviation ...................................69 vi CHAPTER 1: INTRODUCTION What drives the decision to extract? In the early 1900s, few orthodontists extracted teeth due to Angle’s popularity.1 The advent of cephalometrics coupled with clinical evidence of improved treatments via extraction in the 1940s turned the tide to promote extractions in order to improve dental, skeletal, and facial relationships.2 Subsequently, extraction rates rose to almost 75% in the 1960s.3 Current extraction rates are estimated to be between 25 to 30%.4-6 This reflects improved non-extraction techniques and empirical evidence of uncertainty with respect to the stability of extractions.7-14 There exist many objective rating systems to assess malocclusion severity, but the decision to extract is up to the clinician. This study explored clinicians’ opinions regarding extraction treatment because, indeed, every clinician has his or her own opinions of what severity of malocclusion requires extraction treatment. The investigation attempted to organize these opinions on measurements that are common directives regarding extraction and non-extraction treatment. It was the purpose of this study to test the opinion of orthodontists as to the values they hold that direct the 1 need for extractions based on individual measurements. Certainly no orthodontist makes extraction decisions based on a single measurement. Yet, 992 orthodontists completed a survey identifying values which related individual measurements to a need for definite extraction or nonextraction treatment. 2 CHAPTER 2: REVIEW OF LITERATURE Orthodontic Extractions History For over one hundred years, the extraction of teeth to facilitate orthodontic treatment has fostered heavy debate within the profession. Extractions create space to align teeth when crowding is present and to reduce protrusion of the teeth and overlying soft tissues. The alternative to extraction of teeth is expansion of the arches. Therefore, in any borderline case of crowding and/or protrusion, there is a choice to be made: Does one extract or expand? In 1907 Edward Angle proposed that normal occlusion could be achieved through the expansion of arches.1 The widespread acceptance of Dr. Angle’s teachings led to a quarter century of expansion orthodontics showing few examples of tooth extraction. Furthermore, Angle believed that when the teeth were placed in ideal occlusion, the resulting facial features were, regardless of patient opinion, “the best facial appearance for him or her,” and failure of the dentition to remain stable meant a failure on the part of the treating orthodontist to place the teeth in proper occlusion.2 Many early orthodontists believed malocclusions developed after birth and represented the manifestation of “degenerating or growth-perverting 3 influences”3 on the individual; that orthodontic treatment would, therefore, alter the local environment returning the individual to a path of perfection. Angle’s occlusal concepts did not go unopposed. In well-publicized debates, Dr. Calvin Case argued against the idea that man is made perfect and that environment is responsible for malocclusions. In fact, with only rudimentary knowledge of genetics, Case noted that under the “laws of heredity, union of dissimilar types creates inharmonious sizes and relations of teeth and jaws.”3 Case presented cases in which the buccal teeth were in normal occlusion, yet decided protrusion was evident. Those individuals presenting bimaxillary protrusion, and cases which would trade skeletal imbalance for dental protrusion through non-extraction therapy were precisely Case’s reasons for extraction. He noted that non-extraction therapy would result in “almost certain probability of ultimately stamping a most unhappy facial deformity for life upon the patients.”3 Investigations into relapse after non-extraction orthodontic treatment led two men, independently of one another, to the idea that, in some cases, extraction of teeth led to greater stability. Charles Tweed and Raymond Begg modified Angles’ appliance in search of improved 4 therapies. Tweed, dissatisfied with the orthodontic creation of protrusive faces and unstable results, retreated one hundred cases by extracting four first bicuspids; after treatment he noted an improvement in stability and attributed this effect to the placement of the mandibular incisors upright over basal bone.4 Simultaneously, Begg began extracting teeth and likewise noted improved treatment results. Their presentations of finished cases paved the way for a shift in attitude toward extraction. Results of genetic and cephalometric studies further disputed Angle’s belief in the origins of malocclusion and bone adaptation following orthodontic treatment. Stockard and Johnson publicized genetic heritability in crossbred dogs, representing conclusive evidence of inherited malocclusion.5 Brodie et al. published early cephalometric work in which they concluded that “actual bone changes accompanying orthodontic management seem to be restricted to the alveolar process.”6 Stockard and Johnson’s findings flew in the face of previous theory that malocclusions were the result of environmental influence. Likewise, Brodie et al.’s evidence repudiated the belief that bony response occurred anywhere other than the alveolar processes. 5 Historically, there has been little debate regarding the rationale behind extracting teeth. Case advocated extraction to correct dental and soft-tissue protrusion and to prevent the transition of a single protrusive arch coupled with a skeletal imbalance from becoming a double protrusion.3 Eighty years later, Baumrind et al. found crowding, incisor protrusion, and profile improvement to be, in order of importance, the reasons orthodontists extract teeth.7 Lending further support, Paquette et al. found that maxillary and mandibular crowding and protrusion, mandibular irregularity, and profile convexity to be the most significant variables influencing extraction.8 Vaden and Kisel offered a slightly different perspective with respect to the limits of the dentition, such that the decision to extract is guided by the anterior, posterior, vertical, and transverse dimensions. The author noted that extractions may be necessary to preserve the integrity of these dimensions or facial harmony may be sacrificed.9 6 Extraction Trends The first quarter of the twentieth century saw overwhelming support for Angle’s non-extraction approach to treatment. Accordingly, extraction rates hovered near ten percent (Figure 2.1).2 Once the orthodontic community accepted evidence in support of extraction therapy in search of stability, rates of extraction soared to a peak of seventy percent in the 1960s.10 Extraction rates declined during the 70s11 and 80s in response to research which concluded both extraction and non-extraction therapies as being associated with instability.12 In response to improved non-extraction techniques, a public desire for fuller profiles and prominent lips, as well as claims that extraction therapy causes TMD, current extraction rates seem to have settled at approximately thirty percent, nearing the levels of the early 1900s.10,13-15 Extraction Effects Cephalometric studies have clarified the quantitative and qualitative effects of extraction. Quantitative changes include a retrusion of the lips two to four millimeters and an increase in the nasolabial angle by five to ten degrees.16-19 However, Drobocky and Smith noted that 7 Figure 2.1: Extraction rates of the 20th century1 cephalometric differences may not necessarily coincide with subjective interpretation of what is considered desirable or undesirable. Thus, “evaluation of profile esthetics by the quantitative methods…must be interpreted with caution.”16 Further studies have utilized lay people, dentists, and orthodontists to evaluate the effects of extraction and non-extraction treatments. Boley et al. found that neither dentists nor orthodontists could determine which treatment a patient had received any better than a flip of a coin.20 The authors concluded that “fear of a significant detrimental effect on the face is unjustified” with respect to four bicuspid extraction. On the other hand, Xu et al. found a preference for the extraction profile in borderline 8 patients.21 Other studies investigated this conclusion in the long-term. Stephens et al., in a follow-up to the Boley study, concluded that “treatment modality does not affect long-term soft tissue profile changes,” and that there was no preference regarding treatment between lay people and orthodontists, males and females, and the extraction and non-extraction patients.22 Paquette et al. also showed that patients, whether treated extraction or non-extraction, showed no tendency in esthetic preference in the long-term even though choice of treatment created a two millimeter difference in denture and lip protrusion.8 Additionally, the authors found differences at the end of treatment to be similar ten to fifteen years posttreatment. Whether the patients studied were similar prior to treatment or immediately post-treatment, the results laid to rest a decades-old accusation that extraction creates dished-in profiles. The Borderline Patient The borderline patient is that individual caught between definitive extraction and non-extraction; “Empirical evidence of uncertainty exists with these patients.”23 For a patient population which has been estimated by Alexander in the neighborhood of 30%,24 a disproportionate research effort has taken place compared 9 to Class II treatment, a patient population estimated near 15%.2 Much of the debate regarding class II treatment has focused on proper timing and technique. Johnston has drawn the conclusion that early, late, single-phase, or two-phase treatments do little to produce significantly different results. Similarly, the borderline patient “can be treated either way.”8 But when “some skilled clinicians…would be likely to make opposite decisions”21 and disagree “as to whether extraction or nonextraction (sic) therapy was the optimum treatment”,25 the idea that there exists only one, single-best treatment should drive further investigation to establish diagnostic methods to aid the borderline individual. Clinical Classification The most common form of malocclusion treated by orthodontists is tooth-size arch length deficiency (TSALD).2 The National Health and Nutrition Estimates Survey (NHANES III) showed only one third of adults and 45.5% of children ages 8 to 11 have well-aligned mandibular incisors. Additionally, nearly fifteen percent of adolescents and adults have incisor irregularity greater than ten millimeters. 10 Little developed the Irregularity Index to give greater objective and quantitative meaning to ambiguous clinical terminology, e.g., crowding, overlap, irregularity.26 The author noted “epidemiologic studies…would benefit from a quantitative measure” and, in fact, the Irregularity Index found its way into the NHANES III survey discussed above. Mandibular anterior irregularity is measured by adding the linear distances between the five adjacent anterior contact points. perfectly aligned incisors, the score is zero. increases with increasing malalignment. With The score Little noted a score greater than 6.5 millimeters indicates severe irregularity and, thus, greater likelihood for extraction.12,26,27 One will find a substantial gray area in the scientific literature defining the borderline of extraction relating to dental discrepancy (crowding). Carey and McNamara set arbitrary borderlines of 2.5 to 5.0 millimeters and 3 to 6 millimeters, respectively.28,29 Gust, in a search to specifically define the borderline, concluded “the amount of maxillary arch length discrepancy may be the most important factor in differentiating the borderline patient” between extraction and non-extraction treatments.23 The author found the range to be 6 to 8 11 millimeters of discrepancy. Luppanapornlarp and Johnston further developed the borders by describing the amount of discrepancy in definitive extraction and non-extraction cases.18 This study found roughly one millimeter of crowding in either arch to constitute definitive nonextraction, while definitive extraction therapy in the maxillary and mandibular arches was 5.8 and 7.3 millimeters, respectively. Literature defining the borderline of extraction with respect to crowding involves a mixture of Class I and Class II malocclusions. In this regard, Baumrind et al noted “Angle classification appear to tell one little about clinician consensus on extraction.”25 As a rule of thumb, many clinicians have believed leveling the Curve of Spee carries a liability ratio of 1:1; leveling the curve increases incisor protrusion. Tweed advocated tip-backs and Class III elastics during resolution of a deep bite to prevent incisor flaring.30 Recent studies conclude the real effect to be closer to 1:3; for every three millimeters of curve leveled, arch circumference increases one millimeter.31-34 Roth considered 3 to 6 millimeters of curve of Spee mild (1.5 to 3.0 per side),35 and Baldridge added that greater than six millimeters is severe.31 In a borderline extraction case, 12 the deeper the Curve of Spee, the greater the need for extraction. An interarch tooth-size discrepancy may provide incentive to extract in order to establish a proper occlusion. This diagnostic variable has been popularized as the Bolton discrepancy.36 Regardless of its recognition, the task of measuring teeth from first molar to first molar in both arches prevents many clinicians from treatment planning according to interarch discrepancies. Ballard introduced tooth size asymmetry, both intra- and interarch, as a necessary factor in diagnosis and treatment planning and found more than half of his cases had a discrepancy of two millimeters or more, a magnitude preventing ideal occlusion.37,38 Additionally, the author noted “conditions prejudicial to perfect balance of the denture were found in nine patients out of ten.”38 The prevalence of discrepancies of this magnitude should encourage an evaluation of tooth size discrepancy a place in every clinician’s evaluation. Neff, in an effort to simplify diagnostic evaluation, noted an ideal maxillary to mandibular cuspid-to-cuspid ratio of 1.22.39 The anterior Bolton ratio of .772 is an approximation of the inverse of Neff’s findings. As clinicians have utilized interproximal reduction to resolve interarch tooth size discrepancies, 13 Bolton noted a four millimeter limit to anterior reduction.40 Thus, extraction may be necessary to resolve a discrepancy greater than this. A proper assessment of facial, skeletal, and dental symmetry is essential in orthodontic diagnosis. A deviation of the dental midline(s) may indicate a skeletal asymmetry and require surgery for correction. Dental midline deviations in the presence of acceptable facial and skeletal balance can be treated orthodontically; with increasing dental midline deviation, extraction becomes more likely. The literature provides little data on quantity of deviation relating to the borderline of extraction. Cephalometric Classification The analysis of lateral cephalograms has provided orthodontics with standards not only for the hard tissues, but also for the soft tissue profile. As Paquette et al. noted, “comparison between extraction and nonextraction treatments can have meaning only for the borderline patient.”8 The authors found an average two millimeters difference in lip protrusion after treatment. Therefore, it is essential to incorporate the effects of treatment when considering extraction versus non-extraction therapy for each borderline case. 14 There exists a wealth of normative data relative to profile lip position in well-balanced faces. These data allow the clinician to plan treatment in order to achieve the best possible esthetics after treatment. A borderline case with pre-treatment lip protrusion may be better served with extraction. Similarly, a more retrusive profile may be improved without removing teeth. Ricketts first identified the esthetic plane, relating lip position to a line from the nasal tip to soft tissue Pogonion.41 In the aging face, lips become relatively more retruded, creating a natural difference in proper lip positions between different age groups. In the adolescent, the lower lip is about two millimeters behind the esthetic plane, or E line, with a standard deviation of three millimeters. The adult lower lip is ideal about four millimeters behind the E line with a similar standard deviation. Burstone found it advantageous to consider lip position relative to a line connecting subnasale and soft tissue pogonion because it is based on a “plane of minimal variation in the face.”42 The author noted the nose is an area of great variation, “approximately twice” the standard deviation as lower lip protrusion (2.8 versus 1.6). The investigator found the lower lip to be ideally positioned 15 about +2.2mm +/-1.6mm in adolescents. Since lip protrusion can disrupt an otherwise pleasing face, extraction may be necessary the further a patient is from ideal. Another morphological characteristic important in diagnosis is the nasolabial angle. There is a great deal of variation in the literature as to what constitutes the ideal value. In Burstone’s 1967 evaluation of lip relation, the author found a preferable nasolabial angle of 73.8 degrees +/- 8. More recent studies find more suitable values in the range of 90 to 115 degrees.43-46 Extraction of four bicuspids was noted to increase the nasolabial angle 5.2 degrees by Drobocky and Smith.16 Therefore, extraction of teeth in a borderline patient with a nasolabial angle greater than the normative values should be avoided. Facial balance is an issue involving dimensions assessed through lateral and frontal imaging. The dimension common to both views is the vertical. Schudy argues the vertical dimension is the most important to the clinician.47 The study utilized the angle formed at the intersection of the sella-nasion and mandibular planes (SN-MP)to aid in his assessments, and found the value of thirty-three degrees to be average for balanced vertical facial types, with a range of 31 to 34 degrees. Another measure of vertical skeletal relationships is the Frankfort 16 mandibular plane angle (FMA). The FMA provides an additional vertical appraisal to the SN-MP measurement. A normal value for the FMA is in the range of 20 to 30 degrees.48 Values above these normal ranges are associated with skeletal open bite, whereas values below are typically associated with skeletal deep bite. Sassouni and Nanda’s “four bony planes of the face” provide an additional assessment of vertical relationships.49 A center 0, defined as the area of convergence of these planes, when located far posterior to the lateral view of the cranium as a result of hypodivergence of the planes is indicative of a skeletal deep bite. Hyperdivergence of the facial planes creates a center 0 much more anterior and is common in the skeletal open bite type.49,50 Regardless of the clinician’s form of vertical assessment, there is agreement among these measurements regarding extraction and non-extraction therapy. Treatment geared toward achieving facial balance is more likely to extract in skeletal open bite and not extract in cases with skeletal deep bite. Orthodontists may disagree which incisor is of greater diagnostic value, the maxillary versus the mandibular. Consequently, clinical cephalometrics may assess the angular and positional values for both.48,51-53 Charles Tweed used the orientation of the mandibular incisor to aid in 17 treatment planning to create facial balance and harmony.48 He noted a need for “upright” and “vertical” lower incisors. Margolis proposed the incisor mandibular plane angle (IMPA) to quantitatively define these two qualities.54 He proposed IMPA to be 90+/-3 degrees in normal, balanced faces. According to Tweed, this value can range between 85 and 95 degrees, and vary according to ethnicity.48 Values above this range are indicative of extraction to improve functional and esthetic imbalance.53 McNamara found the proper position of the mandibular incisor to be 1 to 3 millimeters anterior to the line from point A to Pogonion (A-Pog) in a well-balanced face, regardless of age.52 Steiner set the ideal positions of the maxillary and mandibular incisors to be four millimeters anterior to the lines connecting Nasion and point A, and Nasion and point B, respectively.51 The maxillary and mandibular incisors should form angles of 22 and 25 degrees to their respective diagnostic lines. Extraction becomes more likely as incisor positions and angles exceed these values. Non-Extraction Treatment Options Treatment to resolve TSALD either involves reduction in tooth mass or expansion of the arches. A reduction in tooth mass may mean extraction of one or more dental units; it may also mean interproximal reduction of enamel. 18 Expansion encompasses those techniques which increase arch length and/or width to stretch the boundaries within which the teeth must fit. Regardless of treatment, the quality of the result is ultimately judged by stability. Proponents of non-extraction therapy have looked to timing of treatment as an ally. Moreira and Araujo sampled 678 patients in a Brazilian orthodontic clinic and found that as growth potential decreased, extraction rates increased.55 Additionally, preservation of arch length can satisfy TSALD in approximately 75% of all patients.56 Gianelly added that this number increases to 84% with the use of a lip bumper to distalize molars one millimeter. Therefore, treatment in the mixed dentition may provide more opportunities to effectively treat the borderline patient non-extraction. Since the 1960s, extraction rates have steadily decreased, due, in part, to increased investigation into expansion/distalization treatments. If “biologic systems are best able to adapt developmentally during periods of maximum change,”57 then mixed dentition therapy may ultimately improve stability. Buschang et al. tested this hypothesis in a series of clinical tests. The authors concluded the lip bumper “can gain or maintain 6-7 millimeters of space without substantially flaring 19 incisors” through a combination of molar expansion and uprighting, incisor tipping, and maintenance of leeway space.57 These findings have been supported by Ferris et al. who concluded results from active, early expansion are stable long-term.58 Other studies elaborate on expansion/distalization techniques which reduce the need for extractions.59,60 McNamara reviewed a series of his expansion/early treatment efforts.29 The author noted that intervention in the mixed dentition utilizing leeway space and rapid maxillary expansion may provide “sufficient arch space to resolve borderline crowding,” which he defined as 3 to 6 millimeters. One might argue against interproximal reduction (IPR) being non-extraction therapy. Because one winds up with less tooth mass, some might say that the only difference between extraction and IPR is an injection. Regardless, whether in the form of an air-rotor disk or lightning strips, IPR provides a viable treatment option for the borderline patient to prevent removal of teeth. Over 45 years ago, Bolton noted a four millimeter limit to anterior stripping.40 Tuverson explained that each incisor surface allows 0.3 millimeters and 0.4 millimeters at the cuspids, totaling 4.0 millimeters.61 Sheridan stretched previous 20 limits of IPR by removing enamel from molar to molar, thus allowing for a cumulative space gain of up to 8.0 millimeters.62 This quantity makes air-rotor stripping an alternative to tooth extraction bridging the gap separating definite extraction and non-extraction with respect to TSALD. Extraction Treatment Options The decision to extract in the borderline case oftentimes hinges on the clinician’s desire for facial change. Non-extraction therapy in the presence of mild denture and lip protrusion may cause a bimaxillary protrusion and facial imbalance. On the other side of the coin, four first bicuspid extraction in a case with mild lip retrusion could create an undesirable facial result. As a result, some clinicians advocate alternative extractions such as second bicuspids or a mandibular incisor to lessen the effect on the soft tissue profile while maintaining stability.61,63-65 Though mandibular incisor extraction may have little effect on the profile and resolves anterior TSALD, there are pitfalls to this treatment which necessitate proper diagnosis and case selection. Bite deepening and increased overjet commonly occur after treatment with only three mandibular incisors. Therefore, clinicians note proper 21 diagnostic criteria to be anterior interarch tooth size discrepancy (Bolton discrepancy of mandibular excess), a diagnostic wax setup, and mandibular anterior crowding.64,65 As opposed to four bicuspid extraction, incisor extraction has other advantages such as reduced treatment time, simpler mechanics, and favorable stability.65 Decision-making Aids In 1948, Downs discussed acceptable ranges of ten diagnostic variables after studying twenty patients with normal occlusions and exhibiting facial balance and harmony.53 This work formed one of the earliest cephalometric analyses in orthodontics. Notably, he concluded “single readings are not so important; what counts is the manner in which they all fit together.” Three years later, Vorhies and Adams took Downs’ analysis one step further to ease the “difficulty of developing a suitable mental picture.”66 The authors organized the data describing acceptable ranges for each characteristic into a wigglegram, an adaptation of Hellman’s early anthropometric work.67 The illustration provided an efficient method to analyze cephalometric measures. In 2002, Rody and Araujo adapted the idea of a wigglegram to facilitate decision-making in Class I 22 borderline extraction cases.68 Similar to Downs’ Wigglegram, the authors illustrated acceptable deviations of diagnostic normative data. Vorhies and Adams related variations of the Downs norms to Class II and Class III characteristics. Rody and Araujo illustrated relationships of dental, skeletal, and facial cephalometric measurements to extraction and non-extraction treatment. In the authors’ Extraction Decision-Making Wigglegram (EDMW), the center line represents the average value for each measurement. For each patient, values to the left of center support extraction, and values to the right support non-extraction. The range of acceptable values for each measurement, both above and below the norm, represent the borderline for each variable. Plotting all diagnostic values on the EDMW allows the clinician to weigh all “votes” for and against extraction. Summary and Statement of Thesis This study aims to investigate current practitioner opinions on values which indicate extraction or nonextraction treatments, and determine what influences gender, length of time as an orthodontic practitioner, and bracket prescription may have on the decision to extract in Class I malocclusions. 23 References 1. Angle EH. Treatment of malocclusion of the teeth. Philadelphia: SS White Manufacturing Co.; 1907. 2. Proffit WR, Fields, H.W. Contemporary Orthodontics. Saint Louis: Mosby; 2000. 3. Case CS. The question of extraction in orthodontia. Dent Cosmos 1912;54:137-157, 276-284. 4. Tweed CH. Indications for the Extraction of Teeth in Orthodontic Procedure. Am J Orthod Dentofacial Orthop 1944;30:405-428. 5. Stockard CR, Johnson, A.L. Genetic and endocrinic basis for differences in form and behavior. Philadelphia: The Wistar Institute of Anatomy and Biology; 1941. 6. Brodie AG, Downs WB, Goldstein A, Myer E. Analysis of changes during and subsequent to orthodontic management of class III malocclusions. Angle Orthod 1938;8:330-351. 7. Baumrind S, Korn EL, Boyd RL, Maxwell R. The decision to extract: Part II. Analysis of clinicians' stated reasons for extraction. Am J Orthod Dentofacial Orthop 1996;109:393-402. 8. Paquette DE, Beattie JR, Johnston LE, Jr. A long-term comparison of nonextraction and premolar extraction edgewise therapy in "borderline" Class II patients. Am J Orthod Dentofacial Orthop 1992;102:1-14. 9. Vaden JL, Kiser HE. Straight talk about extraction and nonextraction: A differential diagnostic decision. Am J Orthod Dentofacial Orthop 1996;109:445-452. 10. Proffit WR. Forty-year review of extraction frequencies at a university orthodontic clinic. Angle Orthod 1994;64:407-414. 24 11. Peck S, Peck H. Frequency of tooth extraction in orthodontic treatment. Am J Orthod 1979;76:491-496. 12. Little RM, Wallen TR, Riedel RA. Stability and relapse of mandibular anterior alignment-first premolar extraction cases treated by traditional edgewise orthodontics. Am J Orthod 1981;80:349-365. 13. O'Connor BM. Contemporary trends in orthodontic practice: a national survey. Am J Orthod Dentofacial Orthop 1993;103:163-170. 14. Turpin DL. Percentage swings in extraction frequencies. Angle Orthod 1994;64:403. 15. Weintraub JA, Vig PS, Brown C, Kowalski CJ. The prevalence of orthodontic extractions. Am J Orthod Dentofacial Orthop 1989;96:462-466. 16. Drobocky OB, Smith RJ. Changes in facial profile during orthodontic treatment with extraction of four first premolars. Am J Orthod Dentofacial Orthop 1989;95:220-230. 17. Germec D, Taner TU. Effects of extraction and nonextraction therapy with air-rotor stripping on facial esthetics in postadolescent borderline patients. Am J Orthod Dentofacial Orthop 2008;133:539-549. 18. Luppanapornlarp S, Johnston LE, Jr. The effects of premolar-extraction: A long-term comparison of outcomes in "clear-cut" extraction and nonextraction Class II patients. Angle Orthod 1993;63:257-272. 19. Talass MF, Talass L, Baker RC. Soft-tissue profile changes resulting from retraction of maxillary incisors. Am J Orthod Dentofacial Orthop 1987;91:385-394. 20. Boley JC, Pontier JP, Smith S, Fulbright M. Facial changes in extraction and nonextraction patients. Angle Orthod 1998;68:539-546. 25 21. Xu TM, Liu Y, Yang MZ, Huang W. Comparison of extraction versus nonextraction orthodontic treatment outcomes for borderline Chinese patients. Am J Orthod Dentofacial Orthop 2006;129:672-677. 22. Stephens CK, Boley JC, Behrents RG, Alexander RG, Buschang PH. Long-term profile changes in extraction and nonextraction patients. Am J Orthod Dentofacial Orthop 2005;128:450-457. 23. Gust JE. A comparative analysis of borderline extraction cases treated in two phases utilizing rapid palatal expansion and lip bumper therapy Orthodontics. Saint Louis: Saint Louis University; 2006: p. 115. 24. Alexander RG. The lip bumper alternative...A better answer for borderline cases. Clinical Impressions 1992;1:80-84. 25. Baumrind S, Korn EL, Boyd RL, Maxwell R. The decision to extract: Part 1--Interclinician agreement. Am J Orthod Dentofacial Orthop 1996;109:297-309. 26. Little RM. The irregularity index: a quantitative score of mandibular anterior alignment. Am J Orthod 1975;68:554563. 27. Little RM. Stability and relapse of mandibular anterior alignment: University of Washington studies. Seminars in Orthodontics 1999;5:191-204. 28. Carey CW. Diagnosis and Case Analysis in Orthodontics. Am J Orthod Dentofacial Orthop 1952;38:149-161. 29. McNamara JA, Jr. Early intervention in the transverse dimension: is it worth the effort? Am J Orthod Dentofacial Orthop 2002;121:572-574. 30. Tweed CH. A philosophy of orthodontic treatment. Am J orthod 1945;31:74-113. 26 31. Baldridge DW. Leveling the curve of Spee: its effect on mandibular arch length. JPO J Pract Orthod 1969;3:26-41. 32. Garcia R. [Leveling of the curve of Spee: A prognostic index]. Orthod Fr 1985;56:503-516. 33. Germane N, Staggers JA, Rubenstein L, Revere JT. Arch length considerations due to the curve of Spee: A mathematical model. Am J Orthod Dentofacial Orthop 1992;102:251-255. 34. Braun S, Hnat WP, Johnson BE. The curve of Spee revisited. Am J Orthod Dentofacial Orthop 1996;110:206-210. 35. Roth RH. Functional occlusion for the Orthodontist. Part III. J Clin Orthod 1981;15:174-179, 182-198. 36. Bolton WA. Disharmony in tooth size and its relation to the analysis and treatment of malocclusion. Angle Orthod 1958;28:113-130. 37. Ballard ML. Asymmetry in tooth size: A factor in the etiology, diagnosis, and treatment of malocclusion. The Angle Orthodontist 1944;14:67-70. 38. Ballard ML. A fifth column within normal dental occlusions. Am J Orthod Dentofacial Orthop 1956;42:116-124. 39. Neff CW. Tailored occlusion with the anterior coefficient. Am J Orthod 1949;35:309-313. 40. Bolton WA. The clinical application of tooth-size analysis. Am J Orthod Dentofacial Orthop 1962;48:504-529. 41. Ricketts RM. Esthetics, environment, and the law of lip relation. Am J Orthod 1968;54:272-289. 42. Burstone CJ. Lip posture and its significance in treatment planning. Am J Orthod 1967;53:262-284. 27 43. Scheideman GB, Bell WH, Legan HL, Finn RA, Reisch JS. Cephalometric analysis of dentofacial normals. Am J Orthod 1980;78:404-420. 44. Lines PA, Lines RR, Lines CA. Profilemetrics and facial esthetics. Am J Orthod 1978;73:648-657. 45. Holdaway RA. A soft-tissue cephalometric analysis and its use in orthodontic treatment planning. Part I. Am J Orthod 1983;84:1-28. 46. Arnett GW, Bergman RT. Facial keys to orthodontic diagnosis and treatment planning. Part I. Am J Orthod Dentofacial Orthop 1993;103:299-312. 47. Schudy FF. Vertical Growth Versus Anteroposterior Growth As Related To Function And Treatment. Angle Orthod 1964;34:75-93. 48. Tweed CH. The diagnostic facial triangle in the control of treatment objectives. Am J Orthod 1969;55:651-657. 49. Sassouni V, Nanda, S. Analysis of dentofacial vertical proportions. Am J Orthod 1964;50:801-823. 50. Sassouni V, Nanda, S. Orthodontics in dental practice. St. Louis: Mosby; 1971. 51. Steiner CC. The use of cephalometrics as an aid to planning and assessing orthodontic treatment: Report of a case. Am J Orthod 1960;46:721-735. 52. McNamara JA, Jr. A method of cephalometric evaluation. Am J Orthod 1984;86:449-469. 53. Downs WB. Variations in facial relationships: Their significance in treatment and prognosis. Am J Orthod 1948;34:812-840. 28 54. Margolis HI. The axial inclination of the mandibular incisors. Am J Orthod Oral Surg. 1943;29:571-594. 55. Moreira R, Araujo, EA. Frequency of extractions at the Graduate Orthodontic Program of the Pontifical Catholic University of Minas Gerais. Rev Bras Ortod Ortop Dentofacial 2000;3:49-53. 56. Gianelly AA. Crowding: timing of treatment. Angle Orthod 1994;64:415-418. 57. Buschang PH, Horton-Reuland, SJ, Legler, L, Nevant, C. Nonextraction approach to tooth size arch length discrepancies with the Alexander discipline. Seminars in Orthodontics 2001;7:117-131. 58. Ferris T, Alexander RG, Boley J, Buschang PH. Long-term stability of combined rapid palatal expansion-lip bumper therapy followed by full fixed appliances. Am J Orthod Dentofacial Orthop 2005;128:310-325. 59. Cetlin NM, Ten Hoeve A. Nonextraction treatment. J Clin Orthod 1983;17:396-413. 60. Ten Hoeve A. Palatal bar and lip bumper in nonextraction treatment. J Clin Orthod 1985;19:272-291. 61. Tuverson DL. Anterior interocclusal relations. Part I. Am J Orthod 1980;78:361-370. 62. Sheridan JJ. Air-rotor stripping. J Clin Orthod 1985;19:43-59. 63. Boley J. An extraction approach to borderline tooth size to arch length problems in patients with satisfactory profiles. Seminars in Orthodontics 2001;7:100-106. 64. Valinoti JR. Mandibular incisor extraction therapy. Am J Orthod Dentofacial Orthop 1994;105:107-116. 29 65. Riedel RA, Little RM, Bui TD. Mandibular incisor extraction--postretention evaluation of stability and relapse. Angle Orthod 1992;62:103-116. 66. Vorhies JM, Adams JW. Polygonic interpretation of cephalometric findings. Angle Orthod 1951;21:194-197. 67. Hellman M. Some biologic aspects: Their implications and application in orthodontic practice. Int J Orth and Oral Surg 1937;23:761-785. 68. Rody WJ, Jr., Araujo EA. Extraction decision-making wigglegram. J Clin Orthod 2002;36:510-519. 30 CHAPTER 3: JOURNAL ARTICLE Abstract Purpose: It was the purpose of this study to test the opinion of orthodontists as to the values they hold that direct the need for extractions based on individual measurements. Methods: A survey of 18 questions pertaining to 9 diagnostic measurements was sent to 10,315 American Association of Orthodontists (AAO) members. Respondents were also asked to indicate his/her gender, years of experience in orthodontics, and general orthodontic technique. were completed. Results: A total of 992 surveys Ranges of responses representing the middle 80% of respondents abutted without overlap for crowding, L1-APog, midline deviation, and Frankfort Mandibular Plane Angle (FMA). Similar ranges overlapped for curve of Spee and Bolton discrepancy while there appeared ranges of values separating the ranges for B-line, Incisor Mandibular Plane Angle (IMPA), and nasolabial angle. Practitioners with fewer than 5 years of experience responded differently from those with more years of experience for 8 of 9 non-extraction measurements. Conclusions: There was an apparent shift toward more protrusive teeth and lips as acceptable treatment goals. Experience plays a significant role in the decision to 31 treat a case non-extraction making the decision to extract more clear-cut. 32 Introduction What drives the decision to extract? In the early 1900s, few orthodontists extracted teeth due to Angle’s popularity.1 The advent of cephalometrics coupled with clinical evidence of improved treatments via extraction in the 1940s turned the tide to promote extractions in order to improve dental, skeletal, and facial relationships.2 Subsequently, extraction rates rose to almost 75% in the 1960s.3 Current extraction rates are estimated to be between 25 to 30%.4-6 This reflects improved non-extraction techniques and empirical evidence of uncertainty with respect to the stability of extractions.7-14 There exist many objective rating systems to assess malocclusion severity, but the decision to extract is up to the clinician. This study explored clinicians’ opinions regarding extraction treatment because, indeed, every clinician has his or her own opinions of what severity of malocclusion requires extraction treatment. The investigation attempted to organize these opinions on measurements that are common directives regarding extraction and non-extraction treatment. It was the purpose of this study to test the opinion of orthodontists as to the values they hold that direct the need for extractions based on individual measurements. 33 Certainly no orthodontist makes extraction decisions based on a single measurement. Yet, 992 orthodontists completed a survey identifying values which related individual measurements to a need for definite extraction or nonextraction treatment. 34 Methods and Materials The opinions of orthodontists regarding the characteristics that influence definite extraction and nonextraction treatment were measured using a survey developed using an online design application.15 A digital format was chosen as an efficient method to control participant anonymity, cost, and ease of use. Each survey recipient was asked to respond to 18 questions pertaining to the nine diagnostic measurements found in Table 3.1. Positive and negative values indicate positions anterior or posterior to the reference line, respectively. For each measurement, the respondent was asked the following question: “When on the borderline of extraction, please indicate the quantity of (measurement) which corresponds to definite extraction” or “non-extraction.” Table 3.1: Survey measurements with respective answer choices Crowding Curve of Spee Bolton discrepancy L1-APog B-line Midline deviation FMA IMPA Nasolabial angle Answer ranges 0mm to 14mm 0mm to 10mm 0mm to 10mm -6mm to +8mm -6mm to +14mm 0mm to 10mm 10° to 50° 70° to 120° 70° to 140° 35 Answer increments 1mm 1mm 1mm 1mm 2mm 1mm 5° 5° 10° Figure 3.1: Example question utilizing visual aid Visual aids were included to better define FMA, IMPA, and L1-APog (Figure 3.1). Additionally, each participant was asked his/her sex, typical orthodontic technique, and years of experience as an orthodontist. Responses to the open-ended question of orthodontic technique were translated into a category that related the type brackets utilized by the practitioner. Only responses which specifically identified bracket prescription were categorized as “pre-adjusted” or “standard edgewise.” All others were categorized as “unknown,” and were not subjected to statistical comparison. Thirty residents and faculty from the Saint Louis University Center for Advanced Dental Education participated in a pilot survey. Participants stated the survey question was unclear and/or ambiguous and needed 36 clarification. Subsequently, the initial version of the survey was modified to produce a final version of greater simplicity and reduced ambiguity. The final version of the survey (Appendix A) was approved by the Board of Directors of the American Association of Orthodontists (AAO) to be sent to all active and lifetime, domestic and international orthodontists and orthodontic residents with a valid email address. The AAO membership database produced a list of 10,315 orthodontists. In order to maintain anonymity and privacy of respondents, the survey was forwarded by the AAO to all email addresses on the list. Results of the survey were recorded and maintained devoid of participant identifiers (e.g., email address) on the SurveyMonkey® server (Surveymonkey.com, Portland, OR). At the end of the two week survey window, data from 992 completed surveys had been collected. All completed survey data collected were analyzed using SPSS 14.0 (SPSS Inc., Chicago, IL). Modes were chosen instead of means to present survey results because answer choices were categorical, not continuous. numbers as answer options. Subjects only had whole So unless the mean value was a whole number, that value could not be selected by any participant. Percentiles were used rather than standard 37 deviations because percentiles lend a better sense of the number of clinicians indicating a range of values. Independent t-tests were used to evaluate differences in the means according to gender and technique. One-way analysis of variance (ANOVA) was used to determine differences related to three experience groupings, 11+ years, 6-10 years, and 0-5 years. When differences were identified, a Bonferroni post hoc test was used to identify differences between group pairs. 38 Results Distribution charts for each measurement can be found in Appendix B. Table 3.2 summarizes the descriptive statistics for the overall survey. Figure 3.2 illustrates modes with respective 10th and 90th percentiles. All values for crowding, curve of Spee, Bolton discrepancy, L1-APog, B-line, and midline deviation are in millimeters and FMA, IMPA, and nasolabial angle are in degrees. Four millimeters was the mode (most common) nonextraction crowding value (Figure 3.3). roughly 1/3 of all respondents. This represented Eighty percent of respondents indicated values between 2mm and 6mm. Table 3.2: Descriptive statistics of completed surveys Non-Extraction Extraction Percentile 10 90 Mode Range Range Crowding 4.0 14 2.0 6.0 8.0 14 6.0 12.0 Curve of Spee 2.0 10 0.0 4.0 4.0 10 3.0 8.0 Bolton 2.0 10 0.0 4.0 6.0 10 2.0 8.0 L1-APog 0.0 14 -4.0 3.0 5.0 14 3.0 7.0 Lip Protrusion Midline Deviation FMA 0.0 20 -4.0 6.0 10.0 12 8.0 14.0 2.0 10 0.0 3.0 4.0 10 3.0 7.0 20.0 40 10.0 30.0 40.0 40 30.0 50.0 IMPA 85.0 50 75.0 95.0 110.0 40 100.0 120.0 Nasolabial Angle 110.0 70 90.0 130.0 70.0 70 70.0 80.0 39 Percentile 10 90 Mode *Non-extraction = red; Extraction = blue Figure 3.2: Survey modes with 10th and 90th percentiles for individual measurements 350 300 250 200 150 100 50 0 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Non-extraction = red; Extraction = blue Figure 3.3: Distribution of responses to millimetric values of crowding 40 Respondents indicated a broader range of values describing the need for extraction due to crowding. Eighty percent of respondents chose extraction from 6mm to 12mm. Eight millimeters of crowding was the mode, representing about 1/4 of respondents. About ½ of respondents chose 2mm of curve of Spee to indicate non-extraction treatment. Eighty percent of respondents indicated non-extraction treatment between 0mm and 4mm of curve of Spee. To indicate a need for extraction, roughly 1/4 of respondents chose 4mm of curve of Spee. Eighty percent of respondents chose a range of 3mm to 8mm of curve of Spee to indicate extraction treatment. The mode for non-extraction Bolton discrepancy was 2mm. This represented roughly 1/3 of respondents. Eighty percent of orthodontists would not extract if the Bolton discrepancy is between 0mm and 4mm. The mode for extraction Bolton discrepancy was 6mm, indicated by more than 1/4 of respondents. Eighty percent of respondents indicated 2mm to 8mm of Bolton discrepancy to represent a need for extraction. Nearly 1/4 of respondents indicated a L1-APog value of 0mm to indicate non-extraction treatment. 41 Values between -4mm and +3mm indicated non-extraction treatment by 80% of respondents. The mode for L1-APog indicating extraction treatment was +5mm. The mode represented more than 1/4 of respondents. Eighty percent of respondents chose values between +3mm and +7mm. The mode for non-extraction B-line was 0mm. 1/4 of respondents indicated this value. Nearly Eighty percent of respondents selected non-extraction B-line vales between 4.0mm and +6.0mm. Respondents provided a narrower range of values to indicate extraction treatment based on the B-line. Eighty percent of respondents selected values from +8mm to +14mm. The mode was +10mm, selected by more than 1/3 of respondents. Eighty percent of respondents indicated non-extraction treatment based upon midline deviations up to 3mm. Roughly 45% of respondents indicated the mode as 2mm of midline deviation. The mode for extraction midline deviation was 4mm. This represented roughly 1/3 of respondents. Eighty percent of respondents selected values between 3mm and 7mm. Eighty percent of respondents indicated non-extraction treatment based upon FMA values between 10° and 30°. 42 The mode was 20°. This value represented more than 1/3 of respondents. The mode for extraction FMA values was 40°. value represented more than 1/3 of respondents. This Values between 30° and 50° were selected by 80% of respondents. Eighty percent of respondents indicated non-extraction treatment based upon IMPA values between 75° and 95° (Figure 3.4). The mode was 85°. This value was selected by more than 1/4 of respondents. Eighty percent of respondents indicated extraction treatment based upon IMPA values between 100° and 120°. Respondents most commonly selected 110°, and this represented roughly 1/3 of respondents. The mode for non-extraction nasolabial angle values was 110°. This represented almost 30% of respondents. Eighty percent of respondents selected values between 90° and 130°. Eighty percent of respondents indicated extraction treatment based upon nasolabial angle values between 70° and 80°. Seventy degrees was commonly selected to indicate extraction treatment. Roughly 70% of respondents selected this value. 43 350 300 250 200 150 100 50 0 70 75 80 85 90 95 100 105 110 115 120 Non-extraction = red; Extraction = blue Figure 3.4: Distribution of responses for IMPA Sex Differences Female respondents tend to require greater discrepancies from normal values than male respondents in deciding when to extract. The mean measurements of male and female respondents show statistically significant extraction differences for crowding, FMA, and nasolabial angle and non-extraction differences for lip protrusion and nasolabial angle (Table 3.3) (p<0.05). Experience Results comparing the means of the three experience groups revealed statistically significant differences in eight of nine non-extraction measurements. 44 All non- Table 3.3: Differences in extraction and non-extraction treatment decisions between female and male respondents. Females Males Extraction Mean SD Mean SD Sig. Crowding 8.4 2.2 8.0 2.4 0.046* Curve of Spee 5.1 2.0 5.1 2.3 0.770 Bolton 5.5 2.2 5.3 2.4 0.305 L1-APog 4.9 1.9 5.0 1.9 0.274 Lip Protrusion 10.6 2.3 10.3 2.3 0.087 Midline Deviation 4.9 1.4 4.8 1.6 0.865 FMA 39.9 6.4 38.9 6.4 0.049* IMPA 108.6 7.3 108.9 6.7 0.589 Nasolabial Angle 73.2 6.5 75.8 11.5 0.005* Non-extraction Crowding 4.1 1.9 4.1 2.0 0.883 Curve of Spee 2.5 1.8 2.4 1.7 0.567 Bolton 2.5 1.5 2.5 1.7 0.553 L1-APog -0.7 2.5 -0.4 2.6 0.088 Lip Protrusion 0.1 3.8 0.9 3.9 0.013* Midline Deviation 2.0 1.1 2.1 1.4 0.194 FMA 20.8 6.9 21.2 7.2 0.480 IMPA 85.7 7.5 86.6 8.4 0.192 Nasolabial Angle 114.6 15.2 110.6 16.2 0.003* * denotes significance of p<0.05 extraction differences were due to the means of the group of least experience. Statistically significant differences were found for all non-extraction variables except midline deviation and extraction crowding, L1-APog, and nasolabial angle (Table 3.4). The post hoc tests determined which groups are different for each measurement (Table 3.5). The only difference between means of the 11+ and 6-10 year experience groups was for extraction based on L1-APog. Statistically significant extraction differences between 45 Table 3.4: Summary of one-way ANOVAs of experience differences in extraction and non-extraction variables Experience Extraction Crowding Curve of Spee Bolton L1-APog B - line Midline Deviation FMA IMPA Nasolabial Angle 11+ years 7.9 5.2 5.3 5.2 10.3 4.9 38.9 108.8 75.9 Non-extraction Crowding 4.1 Curve of Spee 2.5 Bolton 2.5 L1-APog -0.3 B - line 0.9 Midline Deviation 2.2 FMA 21.7 IMPA 86.9 Nasolabial Angle 111.0 * denotes significance p<0.05. 6-10 years 8.3 5.0 5.3 4.8 10.2 4.6 39.2 108.3 74.6 4.5 2.6 2.7 0.0 1.7 2.1 21.4 87.3 109.0 0-5 years 8.6 4.9 5.3 4.6 10.3 4.8 39.8 109.7 73.8 3.9 2.2 2.2 -1.1 -0.3 1.9 19.2 84.2 113.7 Sig. 0.001* 0.151 0.991 <0.000* 0.740 0.059 0.211 0.116 0.045* 0.016* 0.022* 0.049* <0.000* <0.000* 0.143 <0.000* <0.000* 0.023* 11+ and 0-5 years experience groups were found for crowding and L1-APog. For the same groups, non-extraction differences were found for curve of Spee, FMA, IMPA, L1APog, and lip protrusion. There were no extraction differences found between the 0-5 and 6-10 years of experience groups. For the same two groups, there were statistically significant non- extraction differences for crowding, FMA, IMPA, L1-APog, lip protrusion, and nasolabial angle. 46 Table 3.5: Results of Bonferroni post hoc tests comparing the different levels of experience for extraction and non-extraction variables Experience 11+ vs. 6-10 Extraction Crowding 0.283 Curve of Spee 1.000 Bolton 1.000 L1-APog 0.043* B - line 1.000 Midline Deviation 0.053 FMA 1.000 IMPA 1.000 Nasolabial Angle 0.638 Non-extraction Crowding 0.098 Curve of Spee 1.000 Bolton 1.000 L1-APog 0.457 B - line 0.067 Midline Deviation 1.000 FMA 1.000 IMPA 1.000 Nasolabial Angle 0.554 * denotes significance p<0.05 11+ vs. 0-5 0.001* 0.173 1.000 <0.000* 1.000 1.000 0.237 0.253 0.054 0.433 0.027* 0.109 0.001* 0.001* 0.163 <0.000* <0.000* 0.108 6-10 vs. 0-5 0.705 1.000 1.000 1.000 1.000 0.400 1.000 0.164 1.000 0.012* 0.082 0.077 <0.000* <0.000* 1.000 0.012* 0.002* 0.024* Bracket Prescription The comparison of means for respondents utilizing preadjusted versus standard edgewise brackets can be found in Table 3.6. Statistically significant extraction differences were found in crowding, curve of Spee, and nasolabial angle. Non-extraction statistically significant differences were found in crowding and Bolton discrepancy. 47 Table 3.6: Summary of independent t-tests of bracket prescription differences in extraction and nonextraction variables Bracket Prescription Extraction Pre-adjusted Crowding 8.2 Curve of Spee 5.2 Bolton 5.4 L1-APog 5.1 B - line 10.3 Midline Deviation 4.8 FMA 39.2 IMPA 108.8 Nasolabial Angle 74.7 Non-extraction Crowding 4.2 Curve of Spee 2.5 Bolton 2.5 L1-APog -0.4 B - line 1.0 Midline Deviation 2.1 FMA 21.3 IMPA 86.6 Nasolabial Angle 111.2 * denotes significance p<0.05. 48 Standard Edgewise 7.8 4.8 5.1 4.9 10.3 4.7 38.7 108.8 76.8 0.039* 0.033* 0.077 0.167 0.811 0.125 0.337 0.968 0.007* 3.9 2.4 2.3 -0.4 0.5 2.1 20.8 86.4 111.5 0.012* 0.418 0.046* 0.983 0.084 0.955 0.357 0.670 0.787 Sig. Discussion Each orthodontist has an opinion on when it is proper or improper to extract teeth. As evidenced by the number of emails questioning the nature of the survey, forcing an orthodontist to quantify values which indicate extraction treatment based on a single measurement can “hit a nerve.” The specialty of orthodontics does not require its members to answer for their decisions, and so it was expected that some survey recipients would become upset when asked to do so. It was never the purpose of the study to propose extraction guidelines or to even impose an idea of what is proper. Furthermore, the results of this study are not intended to encourage the establishment of extraction guidelines. This study “took the temperature” of current extraction decision-making for Class I malocclusions using nine common diagnostic measurements. While it may be interesting to note average values, some may find it more relevant to know how their own decision-making compares to those who participated in the study. The borderline patient is currently described as one whom provokes indecision, “can be treated either way,” or causes disagreement as to whether extraction or nonextraction therapy is the best treatment.16,17 49 Results show that for crowding, L1-APog, midline deviation, and FMA, the decision to extract becomes more clear-cut at 6mm, 3mm, 3mm, and 30°, respectively. Respondents also indicate that 3mm to 4mm of curve of Spee and 2mm to 4mm Bolton discrepancy can be treated either way, as evidenced by the overlap of ranges for these values. On the other hand, gray areas, illustrated in Figure 3.2 as ranges between the middle 80% of the two decision groups, are found for B-line values between 6mm and 8mm, IMPA values from 95° to 100°, and nasolabial angles between 80° and 90°. The findings of this study, in which 8mm of crowding held significance for the extraction decision, add practical support to the orthodontic literature. Rody and Araujo found that conservative non-extraction treatments for the resolution of crowding have about an 8mm limit.18 Other studies noted borderline crowding limits between 6mm and 8mm.7,19,20 Results for IMPA and B-line show a large number of practitioners tolerating protrusion of the lower incisors and lips. It is somewhat surprising to find practitioners showing ambivalence toward IMPA values between 95° and 100°. According to the literature, IMPA values above 96° indicate esthetic and/or functional impairment, yet many respondents wouldn’t extract until values reach positions 50 rarely found in nature (110° or more).21-23 Furthermore, respondents indicated an unwillingness to extract teeth to improve lip protrusion until treatment couldn’t possibly attain positions indicated by Burstone as being harmonious and in balance (B-line 1mm-4mm).24 These data indicate not only a tolerance for dental and soft tissue protrusion, but also may reveal a preference for it, representing a shift in treatment goals in orthodontics. Experience appears to make the extraction decision more clear-cut. It was found that clinicians push the non- extraction envelope with increasing years of experience. This has the effect of narrowing the ranges of values between the means for definite extraction and nonextraction. Therefore, there is less gray area in extraction decision-making for practitioners with more than 5 years of experience. There exists a lack of research regarding what effects bracket prescription and gender may have on the decision to extract. This study found statistically significant differences for both. However, correlation does not necessarily mean causation. The differences could very well be spurious because the survey forced answers even though clinicians do not base the decision to extract on a single measurement, or because means taken to the tenth of 51 a millimeter or degree were derived from categorical, whole-number answer choices. Nonetheless, these differences are real and call for further investigation. 52 Conclusions This study found that orthodontists indeed have different opinions as to what constitutes a definite need for extraction or non-extraction treatment in Class I malocclusions. It also revealed practitioners will tolerate a more protrusive dentition. Experience plays a significant role in the decision to treat a case nonextraction, and seems to shrink the gray areas describing a borderline patient making the decision more clear-cut. Previous orthodontic literature reveals little regarding what effects experience and gender may have on the extraction decision, and this study reveals a need for consideration of these areas. 53 References 1. Proffit WR, Fields, H.W. Contemporary Orthodontics. Saint Louis: Mosby; 2000. 2. Tweed CH. Indications for the Extraction of Teeth in Orthodontic Procedure. Am J Orthod 1944;30:405-428. 3. Proffit WR. Forty-year review of extraction frequencies at a university orthodontic clinic. Angle Orthod 1994;64:407-414. 4. O'Connor BM. Contemporary trends in orthodontic practice: a national survey. Am J Orthod Dentofacial Orthop 1993;103:163-170. 5. Turpin DL. Percentage swings in extraction frequencies. Angle Orthod 1994;64:403. 6. Weintraub JA, Vig PS, Brown C, Kowalski CJ. The prevalence of orthodontic extractions. Am J Orthod Dentofacial Orthop 1989;96:462-466. 7. McNamara JA, Jr. Early intervention in the transverse dimension: is it worth the effort? Am J Orthod Dentofacial Orthop 2002;121:572-574. 8. Gianelly AA. Crowding: timing of treatment. Angle Orthod 1994;64:415-418. 9. Buschang PH, Horton-Reuland, SJ, Legler, L, Nevant, C. Nonextraction approach to tooth size arch length discrepancies with the Alexander discipline. Sem Orthod 2001;7:117-131. 10. Ferris T, Alexander RG, Boley J, Buschang PH. Long-term stability of combined rapid palatal expansion-lip bumper therapy followed by full fixed appliances. Am J Orthod Dentofacial Orthop 2005;128:310-325. 54 11. Cetlin NM, Ten Hoeve A. Nonextraction treatment. J Clin Orthod 1983;17:396-413. 12. Ten Hoeve A. Palatal bar and lip bumper in nonextraction treatment. J Clin Orthod 1985;19:272-291. 13. Tuverson DL. Anterior interocclusal relations. Part I. Am J Orthod 1980;78:361-370. 14. Sheridan JJ. Air-rotor stripping. J Clin Orthod 1985;19:43-59. 15. Surveymonkey.com. 2008. 16. Paquette DE, Beattie JR, Johnston LE, Jr. A long-term comparison of nonextraction and premolar extraction edgewise therapy in "borderline" Class II patients. Am J Orthod Dentofacial Orthop 1992;102:1-14. 17. Baumrind S, Korn EL, Boyd RL, Maxwell R. The decision to extract: Part 1--Interclinician agreement. Am J Orthod Dentofacial Orthop 1996;109:297-309. 18. Rody WJ, Jr., Araujo EA. Extraction decision-making wigglegram. J Clin Orthod 2002;36:510-519. 19. Luppanapornlarp S, Johnston LE, Jr. The effects of premolar-extraction: A long-term comparison of outcomes in "clear-cut" extraction and nonextraction Class II patients. Angle Orthod 1993;63:257-272. 20. Gust JE. A comparative analysis of borderline extraction cases treated in two phases utilizing rapid palatal expansion and lip bumper therapy Orthodontics. Saint Louis: Saint Louis University; 2006: p. 115. 21. Tweed CH. The diagnostic facial triangle in the control of treatment objectives. Am J Orthod 1969;55:651-657. 55 22. Margolis HI. The axial inclination of the mandibular incisors. Am J Orthod Oral Surg 1943;29:571-594. 23. Downs WB. Variations in facial relationships: Their significance in treatment and prognosis. Am J Orthod 1948;34:812-840. 24. Burstone CJ. Lip posture and its significance in treatment planning. Am J Orthod 1967;53:262-284. 56 APPENDIX A: COPY OF SURVEY 57 58 59 60 61 ‐6 ‐4 ‐2 0 +2 +4 +6 +8 +10 +12 +14 ‐6 ‐4 ‐2 0 +2 +4 +6 +8 +10 +12 +14 62 140° 130° 120° 110° 100° 90° 80° 70° 140° 130° 120° 110° 100° 90° 80° 70° 63 64 APPENDIX B: DISTRIBUTION CHARTS FOR ALL MEASUREMENTS Crowding 350 300 n u m b e r o f r e s p o n s e s 250 200 Extraction 150 Non‐extraction 100 50 0 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 millimeters Figure A.1: Distribution of responses for crowding Curve of Spee 350 300 n u m b e r r e s p o n s o e f s 250 200 Extraction 150 Non‐extraction 100 50 0 0 1 2 3 4 5 6 7 8 9 10 millimeters Figure A.2: Distribution of responses for curve of Spee 65 Bolton Discrepancy 350 300 n u m b e r r e s p o n s o e f s 250 200 Extraction 150 Non‐extraction 100 50 0 0 1 2 3 4 5 6 7 8 9 10 millimeters of discrepancy Figure A.3: Distribution of responses for Bolton discrepancy Frankfort Mandibular Plane Angle 400 n u m b e r r e s p o n s o e f s 350 300 250 200 Extraction 150 Non‐Extraction 100 50 0 10 15 20 25 30 35 40 45 50 Degrees Figure A.4: Distribution of responses for FMA 66 Incisor Mandibular Plane Angle 350 300 n u m b e r r e s p o n s o e f s 250 200 Extraction 150 Non‐extraction 100 50 0 70 75 80 85 90 95 100 105 110 115 120 Degrees Figure A.5: Distribution of responses for IMPA Lower Incisor to A‐Pog 300 n u m b e r r e s p o n s o e f s 250 200 150 Extraction Non‐Extraction 100 50 0 ‐6 ‐5 ‐4 ‐3 ‐2 ‐1 0 1 2 3 4 5 6 7 8 millimeters Figure A.6: Distribution of responses for L1-APog 67 Lower lip to B line (Subnasale to Pog') 400 n u m b e r r e s p o n s o e f s 350 300 250 200 Extraction 150 Non‐extraction 100 50 0 ‐6 ‐4 ‐2 0 2 4 6 8 10 12 14 millimeters Figure A.7: Distribution of responses for B-line Nasolabial Angle 800 700 n u m b e r o f r e s p o n s e s 600 500 400 Extraction Non‐extraction 300 200 100 0 140 130 120 110 100 90 80 degrees Figure A.8: Distribution of responses for nasolabial angle 68 70 Midline Deviation 500 450 n u m b e r r e s p o n s o e f s 400 350 300 250 Extraction 200 Non‐extraction 150 100 50 0 0 1 2 3 4 5 6 7 8 9 10 millimeters Figure A.9: Distribution of responses for midline deviation 69 VITA AUCTORIS Samuel I. Gentry was born on the 17th of March 1980 in Clarksville, TN. He is the middle of three children. Dr. Gentry graduated from Northeast High School in 1998. He obtained his Bachelor’s degree in Biochemistry and Molecular Biology with a minor in Economics from Mississippi State University in 2002. He obtained his Doctor of Dental Surgery degree upon graduation from the University of Tennessee, College of Dentistry in 2006. He was accepted into the orthodontic residency program at Saint Louis University that same year where he is currently a candidate for the degree of Master of Science in Dentistry. Dr. Gentry married his wife, Stephanie, during his residency in March 2008. They plan to move to Clarksville, TN where he will pursue private practice upon graduation in January 2009. 70