Download Optimization of Phase Contrast Imaging

Optimization of Phase
Contrast Imaging
Luke Powers
Chris Weaver
Jonathan Fermo
Alfred Luk
Phase-Contrast Radiography
 Traditional
radiography uses differences in
absorption to develop images
 Phase-contrast Radiography (PC-R) uses
differences in refraction and diffraction in
the tissue
16 keV
Mouse Pelvis
29 keV
http://www.mxisystems.com/images.html
Phase-Contrast Radiography
 Edge
enhancements unique to PC-R
 Result of combination between
constructive and destructive
interference
Potential
 Has
potential to detect objects that are
invisible on conventional radiography
 Edge enhancements and early
detection of breast cancer
 Monochromatic beam reduces excess
radiation dosage to patient
Advisors

Advisors:




Frank E. Carroll,
M.D.
Gary Shearer
Robert Traeger
Principal
Investigator:

Edwin Donnelly,
M.D., Ph.D.
Facilities
 W.M.
Keck Free
Electron Laser
Center at
Vanderbilt
 Vanderbilt BME
Department
Resources

Monochromatic Xray source at FEL
 LabVIEW and
Virtual Instruments
 Stages, controllers,
etc… for design
construction
provided by FEL &
outside contractors
Objectives
 To
build a device that aids in testing PCR parameters
 Requires controlled movement in the x-,
y-, & z-axes
 Rotation in the x-y plane
 Computer interface for real-time control
Parameters

Distances:



Movements:




Source-to-object ≤ 5 meters
Object-to-detector ≤ 1 meter
x-,y-axes ≤ 15 cm (total)
z-axis ≤ 1 meter (per side)
360° rotation
Independent object & detector movement
along z-axis
Components
 Software
(LabView)
 Microcontroller
 Stepper Drivers
 Stepper Motors (200 steps/revolution)
 Can
 Linear
micro-step for up to 64,000 steps/rev
Translation Stages (x,y,z)
 Rotational Stage
Selected Components
Microcontroller Linear Translation Stage (z)
Selected Components

Detector and
Rotational Stage