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Cell Growth and Division Mrs. Nell’s Life Science Class Cells • Your body cells are constantly growing, dividing, and dying. This is true for animal cells and plant cells. Most of the life of any cell is spent in a period of growth and development called interphase. Cells in your body that no longer divide (like nerve and muscle cells) are always in interphase. Mitosis Cells divide in two steps. First, the nucleus of the cell divides, and then the cytoplasm divides. Mitosis is the process in which the nucleus divides to form two identical nuclei. Each of the two nuclei contains the same number and type of chromosomes as the original. Steps of Animal Mitosis Stage 1: Interphase • Nucleus can be clearly seen. • Chromosomes (structures in the nucleus that contain DNA) cannot be seen but are actively copying themselves. • When the cell is ready to divide the chromosomes become visible. They are thick and double stranded and are held together at a region called a centromere. Steps of Animal Mitosis Stage 2: Prophase • Chromosomes can now be clearly seen. • Nucleolus and nuclear membrane fade and disappear. • Centrioles (cylinder shaped organelles found in the nucleus of a cell) move to opposite ends of the cell. • Between the centrioles, spindle fibers begin to stretch across the cell. Steps of Animal Mitosis Stage 3: Metaphase • Double-stranded chromosomes line up across the center of the cell. • Each centromere attaches to a spindle fiber. Steps of Animal Mitosis Stage 4: Anaphase • Centromeres divide. • Two strands of each chromosome separate. • Separate strands move away from each other toward opposite ends of the cell. (Each ‘daughter cell’ now has an identical set of genes) Steps of Animal Mitosis Stage 5: Telophase • Centrioles and spindle fibers start to disappear. • Chromosomes stretch out and become harder to see. • Nuclear membrane forms around each mass of chromosomes. • New nucleolus appears in each new nucleus. Cell Division- Animal Cells • Once the nucleus has divided, the cytoplasm also separates and two whole new cells are formed. • In animal cells, the cytoplasm pinches in to form the new cells, then the cycle starts all over again. Cell Division- Plant Cells • Plant cells have rigid cell walls and do not pinch apart as animal cells do. • In plant cells a cell plate forms between the two new nuclei. New cell walls form along the cell plate. • Plant cells do not have centrioles, but they do have spindle fibers during mitosis. Results of Mitosis • Remember- mitosis is the division of a nucleus. • Mitosis produces two new nuclei that have the same number of chromosomes as the original nucleus (human body cells have 46 chromosomes… new body cells will have 46 chromosomes as well). Websites to See on Mitosis http://highered.mcgraw-hill.com/sites/0073031216/student_view0/exercise13/mitosis_movie.html Websites to See on Mitosis Asexual Reproduction • Your body forms two types of cells- body cells and sex cells. • Sex cells are the egg or sperm in the reproductive organs. • In asexual reproduction new organisms are produced from one parent. • Offspring produced by asexual reproduction have DNA identical to the DNA of the parent organism. Examples of Asexual Reproduction Planaria regenerating Yeast budding Hydra budding Budding: asexual reproduction in which a new organism grows from the body of the parent organism Regeneration: asexual reproduction in which an organism repairs damaged or lost body parts Fission: asexual reproduction in which organism divides into two equal parts Examples of Asexual Reproduction (II) Newt limb regeneration Sponge regeneration Bacteria fission Strawberry plant runner Sea star regeneration Spider plant runner Sexual Reproduction and Meiosis • In sexual reproduction a new organism is produced when sex cells from two parents combine. • The sex cell from the male parent is called the sperm. • The sex cell from the female parent is called the egg. • Meiosis is the process of nuclear division that produces sex cells (takes place in reproductive organs of both plants and animals). Importance of Sex Cells • Human sex cells have 23 chromosomes, not 23 pairs of chromosomes. Sex cells are haploid (contain only one chromosome from each pair). • A cell that has two of every kind of chromosome is diploid. Body cells which have 23 pairs of chromosomes are diploid. Fertilization • The joining of an egg and a sperm is called fertilization. • The cell that forms in fertilization is called a zygote. • A zygote has 46 chromosomes and is, therefore, diploid. Meiosis • In meiosis there are two divisions of the nucleus, meiosis I and meiosis II. Meiosis I • Prophase I • double-stranded chromosomes and spindle fibers appear. • Nuclear membrane and nucleolus disappear. • Like chromosomes come together in matching pairs. Meiosis I • Metaphase I • Pairs of chromosomes line up in the center of the cell. • Centromeres attach to spindle fibers. Meiosis I • Anaphase I • Double-stranded chromosomes separate. • Chromosomes are pulled to opposite ends of the cell. Meiosis I • Telophase I • Cytoplasm divides and two cells form. • Each chromosome is still double-stranded. Meiosis II • Prophase II • Double-stranded chromosomes and spindle fibers reappear in each new cell. Meiosis II • Metaphase II • Double-stranded chromosomes move to center of cell. • Centromeres attach to spindle fibers. Meiosis II • Anaphase II • Centromere divides. • Two strands of each chromosome separate and move to opposite ends of the cell. Meiosis II • Telophase II • Spindle fibers disappear. • Nuclear membrane forms around the chromosomes at each end of the cell. • Each nucleus contains half the number of chromosomes that were in the original nucleus. (23 single-stranded chromosomes for human body cells). End Product Comparing Mitosis and Meiosis Feature Mitosis Meiosis What type of cell Body cell Sex cell Beginning cell Diploid Diploid Number of cells produced Two Four End-product cell Diploid Haploid Number of chromosomes produced Same as parent- 46 Half the parent cell number- 23 Image Bibliography http://sylva.for.ulaval.ca/foret/mitose/interpro.jpeg http://www.bmb.psu.edu/courses/biotc489/notes/prophase.jpg http://www2.marianopolis.edu/BIO-NYA/cell%20_division/anaphase.jpg http://virtual.yosemite.cc.ca.us/randerson/Lynn's%20Bioslides/88.jpg http://www.bmb.psu.edu/courses/biotc489/notes/telophas.jpg http://www.microscopy-uk.org.uk/mag/imgaug99/whole.jpg http://bio.winona.msus.edu/berg/IMAGES/cytokinP.gif http://ad2004.com/Biblecodes/matimages/Chromosome1.gif http://www3.ac-clermont.fr/10-15/ressources/sciences/experimentation/regeneration.jpg http://www.evzonemusic.com/sponges.jpg http://zom.free.fr/images/sea/sea_star.JPG http://www.karlloren.com/biopsy/images/TEM-Fission_rod.jpg http://strawberry.ifas.ufl.edu/runnering%20plant%202.jpg http://www.vetmed.iastate.edu/departments/vdpam/swine/basics/anatomy/repro/labels/AI%20sperm%20normal%20label.JPG http://cgee.hamline.edu/see/crs_and_concept/cycle_ovum.jpg http://imiloa.wcc.hawaii.edu/krupp/BIOL101/present/lectur14/img005.jpg http://sprott.physics.wisc.edu/pickover/zygote.jpg http://genetics.gsk.com/graphics/meiosis.gif http://mil.citrus.cc.ca.us/cat2courses/bio104/ChapterNotes/images/ch9/0171cl.jpg