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Transcript
1372, either, cat. 11 CORONARY ARTERY CALCIFICATION AND ITS RELATION TO SYSTOLIC FUNCTION ESTIMATED BY MSCT IN CHRONIC CORONARY DISEASE I.M. Burazor1, Z. Radovanovic1, M. Burazor1, P. Bosnjakovic1, D. Ilic1, S. Susak2, M. Lazovic1, Z. Perisic1, Z. Burazor1, N. Burazor3 1 Clinical Center Nis, Serbia, 2Institute for Cardiovascular Diseases Sremska Kamenica, 3Medical Faculty, Nis, Serbia Multislice computer tomography (MsCT) might be a useful clinical tool in detection of coronary artery calcium score and stenosis. The tridimensional estimation of global left ventricular (LV) function, in addition, might be performed. We aimed to evaluate coronary artery calcification and its relation to LV function estimated by MsCT in chronic coronary artery disease. Patients and Methods: Out of 758 persons who were referred to 64 slices MSCT, the total of 156 (age 50 to 69 years, 64% males) in sinus rhythm with chronic coronary artery disease were included in the study. Coronary artery calcification (CAC) score was calculated for each vessel and in total. Noninvasive angiography was performed to detect significant lesions. Global LV function was assessed by MSCT (ejection fraction, stroke volume, cardiac output, LV volume, LV mass, end-systolic and enddiastolic volumes). Results: All patients had CAC score ranging from 1 to 1000. CAC score between 1 and 100 was detected in 25% of patients; 101 to 399 in 22%; 400 to 999 in 30%. 23% had CAC score above 1000. Higher CAC correlated with lower ejection fraction (p=0.01), stroke volume (p=0.05), end –systolic volume (p=0.01) and end-diastolic volume (p=0.05). Also, CAC correlated with years of age and male gender. Significant lesions were detected in 16%. Conclusions: High coronary artery calcifications correlated with decreased LV systolic function in patients with chronic ischemic heart disease. Further studies will determine the ultimate role of CAC score and its relationship to global left ventricular function.
