
Role of Magnesium in Cardiac Disease
... deviation of Mg2* determinations makes it difficult to detect a decrease from the normal level in the ränge of < 10% äs is the case in mild Mg2"1" deficiency. The broad Variation of normal serum Mg2* levels may be caused not only by individual Variation in intake and intestinal absorption but also b ...
... deviation of Mg2* determinations makes it difficult to detect a decrease from the normal level in the ränge of < 10% äs is the case in mild Mg2"1" deficiency. The broad Variation of normal serum Mg2* levels may be caused not only by individual Variation in intake and intestinal absorption but also b ...
Assessment Report - Medical Services Advisory Committee
... Morona JK, Kessels S, Vogan A, Mittal R, Newton S, Parsons J, Milverton J, Ellery B and Merlin T. (2016). Cardiac MRI for myocardial stress perfusion and viability imaging in patients with known or suspected coronary artery disease. MSAC Application Number 1237, Assessment Report. Commonwealth of Au ...
... Morona JK, Kessels S, Vogan A, Mittal R, Newton S, Parsons J, Milverton J, Ellery B and Merlin T. (2016). Cardiac MRI for myocardial stress perfusion and viability imaging in patients with known or suspected coronary artery disease. MSAC Application Number 1237, Assessment Report. Commonwealth of Au ...
The Role of Aspirin in Cardiovascular Prevention
... Aspirin is well recognized as an effective antiplatelet drug for secondary prevention in subjects at high risk of cardiovascular events. However, most patients receiving long-term aspirin therapy still remain at substantial risk of thrombotic events due to insufficient inhibition of platelets, speci ...
... Aspirin is well recognized as an effective antiplatelet drug for secondary prevention in subjects at high risk of cardiovascular events. However, most patients receiving long-term aspirin therapy still remain at substantial risk of thrombotic events due to insufficient inhibition of platelets, speci ...
Advances in Environmental Biology
... appropriate drug regime can be resolute for each individual [17-20]. A modified PCR-RFLP technique was used to determine the details of CYP2C19 polymorphism in East Azerbaijan Province of Iran. The PCR-RFLP method is a rapid and simple technique for detecting genetic defects [21]. Zalloum reported t ...
... appropriate drug regime can be resolute for each individual [17-20]. A modified PCR-RFLP technique was used to determine the details of CYP2C19 polymorphism in East Azerbaijan Province of Iran. The PCR-RFLP method is a rapid and simple technique for detecting genetic defects [21]. Zalloum reported t ...
DIPYRIDAMOLE TABLETS USP 25 MG, 50 MG AND 75 MG
... the dipyridamole tablets were begun between 24 hours and 10 days postoperatively. The length of follow-up in these trials varied from 1 to 2 years. Dipyridamole tablets do not influence prothrombin time or activity measurements when administered with warfarin. Mechanis m of Action Dipyridamole inhib ...
... the dipyridamole tablets were begun between 24 hours and 10 days postoperatively. The length of follow-up in these trials varied from 1 to 2 years. Dipyridamole tablets do not influence prothrombin time or activity measurements when administered with warfarin. Mechanis m of Action Dipyridamole inhib ...
Statins - Amazon Web Services
... In the United States, coronary heart disease and cardiovascular disease account for nearly 40% of all deaths each year. Coronary heart disease continues to be the leading cause of mortality and a significant cause of morbidity among North Americans. In 2006, coronary heart disease claimed 607 000 li ...
... In the United States, coronary heart disease and cardiovascular disease account for nearly 40% of all deaths each year. Coronary heart disease continues to be the leading cause of mortality and a significant cause of morbidity among North Americans. In 2006, coronary heart disease claimed 607 000 li ...
Drug Class Review HMG-CoA Reductase Inhibitors (Statins) and
... In the United States, coronary heart disease and cardiovascular disease account for nearly 40% of all deaths each year. Coronary heart disease continues to be the leading cause of mortality and a significant cause of morbidity among North Americans. In 2006, coronary heart disease claimed 607 000 li ...
... In the United States, coronary heart disease and cardiovascular disease account for nearly 40% of all deaths each year. Coronary heart disease continues to be the leading cause of mortality and a significant cause of morbidity among North Americans. In 2006, coronary heart disease claimed 607 000 li ...
Magnesium and cardiovascular system
... metabolic syndrome, mortality rate from CAD and all causes. Magnesium supplementation improves myocardial metabolism, inhibits calcium accumulation and myocardial cell death; it improves vascular tone, peripheral vascular resistance, afterload and cardiac output, reduces cardiac arrhythmias and impr ...
... metabolic syndrome, mortality rate from CAD and all causes. Magnesium supplementation improves myocardial metabolism, inhibits calcium accumulation and myocardial cell death; it improves vascular tone, peripheral vascular resistance, afterload and cardiac output, reduces cardiac arrhythmias and impr ...
Aspirin Dosing for the Prevention and Treatment of Ischemic Stroke
... The efficacy of aspirin for the primary prevention of stroke has been evaluated in men and women. Five pivotal trials are often cited in recommendations for the use of aspirin in high-risk patients. Of these, 2 included men only, 1 randomized women only, and 2 randomized both men and women. Peto and ...
... The efficacy of aspirin for the primary prevention of stroke has been evaluated in men and women. Five pivotal trials are often cited in recommendations for the use of aspirin in high-risk patients. Of these, 2 included men only, 1 randomized women only, and 2 randomized both men and women. Peto and ...
Potential arrhythmogenic role of cyclic adenosine
... Evidence Against the Cyclic AMP Hypothesis Nonetheless, evidence against a relation between tissue cyclic AMP levels and the occurrence of ventricular fibrillation has been provided by two, sources . First, forskolininduced increases in cyclic AMP levels in isolated rat hearts were not accompanied b ...
... Evidence Against the Cyclic AMP Hypothesis Nonetheless, evidence against a relation between tissue cyclic AMP levels and the occurrence of ventricular fibrillation has been provided by two, sources . First, forskolininduced increases in cyclic AMP levels in isolated rat hearts were not accompanied b ...
Cardiological Society of India
... angiographically proven coronary artery disease (CAD) in 128 patients with a mean age of 56.4±9.1 years (116 males, 12 females). There were 36 (28%) diabetic, 46 (36%) hypertensive, 30 (23%) smoker and 16 (13%), with a positive family history of CAD. The mean triglyceride, total cholesterol, high-de ...
... angiographically proven coronary artery disease (CAD) in 128 patients with a mean age of 56.4±9.1 years (116 males, 12 females). There were 36 (28%) diabetic, 46 (36%) hypertensive, 30 (23%) smoker and 16 (13%), with a positive family history of CAD. The mean triglyceride, total cholesterol, high-de ...
ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction
... reported orally to all members of the writing panel at the first meeting, and updated and reviewed by the writing committee as changes occur. These practice guidelines are intended to assist healthcare providers in clinical decision making by describing a range of generally acceptable approaches for ...
... reported orally to all members of the writing panel at the first meeting, and updated and reviewed by the writing committee as changes occur. These practice guidelines are intended to assist healthcare providers in clinical decision making by describing a range of generally acceptable approaches for ...
ACC/AHA 2004 STEMI Guidelines
... reported orally to all members of the writing panel at the first meeting, and updated and reviewed by the writing committee as changes occur. These practice guidelines are intended to assist healthcare providers in clinical decision making by describing a range of generally acceptable approaches for ...
... reported orally to all members of the writing panel at the first meeting, and updated and reviewed by the writing committee as changes occur. These practice guidelines are intended to assist healthcare providers in clinical decision making by describing a range of generally acceptable approaches for ...
Regulation of Coronary Blood Flow During Exercise
... Duncker DJ, Bache RJ. Regulation of Coronary Blood Flow During Exercise. Physiol Rev 88: 1009 –1086, 2008; doi:10.1152/physrev.00045.2006.—Exercise is the most important physiological stimulus for increased myocardial oxygen demand. The requirement of exercising muscle for increased blood flow neces ...
... Duncker DJ, Bache RJ. Regulation of Coronary Blood Flow During Exercise. Physiol Rev 88: 1009 –1086, 2008; doi:10.1152/physrev.00045.2006.—Exercise is the most important physiological stimulus for increased myocardial oxygen demand. The requirement of exercising muscle for increased blood flow neces ...
INCIDENCE, PREDICTORS AND OUTCOMES OF MYOCARDIAL
... Transcatheter aortic valve replacement (TAVR) has emerged as a less invasive therapeutic alternative to surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis at very high-risk or prohibitive perioperative risk. Compared to conventional openheart surgery, TAVR procedures a ...
... Transcatheter aortic valve replacement (TAVR) has emerged as a less invasive therapeutic alternative to surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis at very high-risk or prohibitive perioperative risk. Compared to conventional openheart surgery, TAVR procedures a ...
Newly Formed Reticulated Platelets Undermine Pharmacokinetically
... thrombopoiesis has been proposed as a contributing factor to high on-treatment platelet reactivity. Here, we investigate the influences of platelet turnover on platelet aggregation in the face of different dual-antiplatelet therapy strategies. Approach and Results—Traditional light transmission aggr ...
... thrombopoiesis has been proposed as a contributing factor to high on-treatment platelet reactivity. Here, we investigate the influences of platelet turnover on platelet aggregation in the face of different dual-antiplatelet therapy strategies. Approach and Results—Traditional light transmission aggr ...
2013 Multimodality Appropriate Use Criteria for
... or low risk limited the benefit of most testing except exercise electrocardiogram (ECG). Testing for the evaluation of new or worsening symptoms following a prior test or procedure was found to be Appropriate. In addition, testing was found to be Appropriate or May Be Appropriate for patients within ...
... or low risk limited the benefit of most testing except exercise electrocardiogram (ECG). Testing for the evaluation of new or worsening symptoms following a prior test or procedure was found to be Appropriate. In addition, testing was found to be Appropriate or May Be Appropriate for patients within ...
ACCF/AHA/ASE/ASNC/HFSA/HRS/SCAI/SCCT/SCMR/STS 2013
... or low risk limited the benefit of most testing except exercise electrocardiogram (ECG). Testing for the evaluation of new or worsening symptoms following a prior test or procedure was found to be Appropriate. In addition, testing was found to be Appropriate or May Be Appropriate for patients within ...
... or low risk limited the benefit of most testing except exercise electrocardiogram (ECG). Testing for the evaluation of new or worsening symptoms following a prior test or procedure was found to be Appropriate. In addition, testing was found to be Appropriate or May Be Appropriate for patients within ...
ESC 2002 - Medscape
... tested suboptimal levels of losartan. Dose is critical–-we haven’t tested proper doses of losartan yet. “The whole rationale in this field is moving toward complete blockade of this axis, so to use a very low dose goes counter to the thinking of how this pathway can be best inhibited and outcomes ...
... tested suboptimal levels of losartan. Dose is critical–-we haven’t tested proper doses of losartan yet. “The whole rationale in this field is moving toward complete blockade of this axis, so to use a very low dose goes counter to the thinking of how this pathway can be best inhibited and outcomes ...
Pharmacokinetic and Pharmacodynamic Responses to
... Clopidogrel functions only when absorbed by the intestine after oral administration. Evidence has shown that clopidogrel absorption is limited by the intestinal efflux transporter P-glycoprotein (P-gp) encoded by ABCB1 gene. Taubert et al. firstly demonstrated that variable intestinal clopidogrel ab ...
... Clopidogrel functions only when absorbed by the intestine after oral administration. Evidence has shown that clopidogrel absorption is limited by the intestinal efflux transporter P-glycoprotein (P-gp) encoded by ABCB1 gene. Taubert et al. firstly demonstrated that variable intestinal clopidogrel ab ...
Angina pectoris
... prophylaxis (prior to physical activity known to induce acute angina • ISDN/ISMN for chronic angina: daytime for exertional angina, nighttime for nocturnal angina • prevention of nitrate tolerance • improve exercise duration; not shown to ↓ mortality ...
... prophylaxis (prior to physical activity known to induce acute angina • ISDN/ISMN for chronic angina: daytime for exertional angina, nighttime for nocturnal angina • prevention of nitrate tolerance • improve exercise duration; not shown to ↓ mortality ...
Ticagrelor Protects the Heart Against Reperfusion Injury and
... events.1 A combination of aspirin with P2Y12 receptor antagonists is recommended by the guidelines for patients with ACS, including ST-segment–elevation myocardial infarction (STEMI).2–6 P2Y12 receptor antagonists block ADP-induced platelet aggregation, which is one of the main amplification pathway ...
... events.1 A combination of aspirin with P2Y12 receptor antagonists is recommended by the guidelines for patients with ACS, including ST-segment–elevation myocardial infarction (STEMI).2–6 P2Y12 receptor antagonists block ADP-induced platelet aggregation, which is one of the main amplification pathway ...
2012 Dyslipidemia Guidelines: Statin Intolerance and Adverse Effects
... Black et al. JAMA 1990; 264:1105 • Study with objective measures of sleep showed no effect Ehrenberg et al. Sleep 1999; 22:117 ...
... Black et al. JAMA 1990; 264:1105 • Study with objective measures of sleep showed no effect Ehrenberg et al. Sleep 1999; 22:117 ...
DOI: 10.1161/CIRCULATIONAHA.108.191098 published online Feb
... right arm, left arm, and left leg electrodes. The negative electrode for the 3 aV (or augmented) limb leads (aVR, aVL, and aVF) is provided by the averaged inputs from the 2 limb electrodes that do not serve as the positive electrode for a specified lead; for example, for aVR, the averaged potential ...
... right arm, left arm, and left leg electrodes. The negative electrode for the 3 aV (or augmented) limb leads (aVR, aVL, and aVF) is provided by the averaged inputs from the 2 limb electrodes that do not serve as the positive electrode for a specified lead; for example, for aVR, the averaged potential ...
DOI: 10.1161/CIR.0b013e318212bb8b published online Mar 28
... This document was approved by the American College of Cardiology Foundation Board of Trustees and by the American Heart Association Science Advisory and Coordinating Committee, and the sections that have been updated are indicated with hyperlinks to the focused update where applicable. When citing t ...
... This document was approved by the American College of Cardiology Foundation Board of Trustees and by the American Heart Association Science Advisory and Coordinating Committee, and the sections that have been updated are indicated with hyperlinks to the focused update where applicable. When citing t ...
Drug-eluting stent

A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly releases a drug to block cell proliferation. This prevents fibrosis that, together with clots (thrombi), could otherwise block the stented artery, a process called restenosis. The stent is usually placed within the peripheral or coronary artery by an interventional cardiologist or interventional radiologist during an angioplasty procedure.Drug-eluting stents in current clinical use were approved by the FDA after clinical trials showed they were statistically superior to bare-metal stents for the treatment of native coronary artery narrowings, having lower rates of major adverse cardiac events (usually defined as a composite clinical endpoint of death + myocardial infarction + repeat intervention because of restenosis). The first drug-eluting stents to be approved in Europe and the U.S. were coated with paclitaxel or an mTOR inhibitor, such as sirolimus.