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HAP 2012-2013 Susan Chabot Early ideas • Linked disease with evil spirits. • Treatment involved ridding the patient of the evil spirit. • Treatment was provided by clergy or witch doctors. 4000 BC - 3000 BC Primitive times • Illness and disease caused by supernatural spirits/demons. • Ceremonies used to drive-out evil spirits. • Herbs and plants were used for medication. • Skeletal evidence demonstrates surgery. • Average life span = 20 years. Trepanation • Involved cutting a small hole in the skull with a special instrument. • Used to treat headaches, skull fractures, epilepsy, and mental illness. • Procedure lasted into the Middle Ages. Peru, 7000 BC Peru, 6000 BC. 2000 BC – 300 BC Ancient Egypt • Earliest known health records. • Offerings to gods for healing. • Use of blood-letting and leeches as treatment. • Herbs and plants used as medicine Ancient papyrus • Average life span = 20 to 30 years. Imhotep 1700 BC – 220 AD Ancient Chinese • Monitored pulse rate to determine the condition of the body. • Believed in curing whole body by curing the spirit and nourishment: Yin and Yang • First recorded “pharmacy” of herbs. • Average life span = 20 - 30 yrs. 1200 BC – 200 BC Ancient Greeks Hippocrates • The start of the Hippocratic tradition “will cause no harm to the patient”. • Believed illness the result of natural causes. • Introduced concept that good diet and cleanliness prevented disease. • Average life span = 25 to 35 years. 753 BC – 410 AD Ancient Romans • • • • Organized medical care for wounded soldiers. Separation of well and sick. Public health and sanitation systems. Diet, exercise and medication used to treat disease. • Average life span = 25 to 35 years. Surgical hooks 400 – 800 AD Dark Ages • Study of medicine was prohibited. • Prayer used to treat disease. • Monks and priests provided care. • Average life span = 20 to 30 years. 800 – 1400 AD Middle Ages • Medical universities open in the 9th century. • Pandemic of bubonic plague occurred. • Chemistry advances in pharmacology. • Average life span = 20 to 35 years. The Black Death • Infectious disease caused by bacterium. • Estimated to have killed 25 million people. • Spread by fleas that fed on rats and humans. • Mongol soldiers catapulted infected corpses over city walls in acts of biowarfare. Gangrene on fingertips 1350 – 1650 AD Renaissance • Dissection allowed for better understanding of A&P. • Artists used dissection to give art a more realistic look. David, by Michelangelo da Vinci • Average life span = 30 to 40 years. Andreas Vesalius 1514-1564 • Illustrated and published first anatomy book. • Performed intricate dissections and drew what he observed. 16th and 17th Centuries • Causes of disease still unknown. • Many died from infection and childbirth fever. • Apothecaries made, prescribed, and sold medications. • Average life span = 35 to 45 years. Mortar & pestle Ambroise Pare 1510-1590 • French surgeon, known as the Father of Modern Surgery. • Introduced amputation to treat soldiers. • Began using ligatures to stop bleeding and bind arteries instead of boilingoil cauterization. • Promoted use of artificial limbs. Anton van Leeuwenhoek 1632-1723 • Invented an early microscope. 18th Century • • • • Fahrenheit created first mercury thermometer. Priestly discovered the element oxygen. Ben Franklin invented bifocals for glasses. Jenner developed first smallpox vaccine. • Average life span = 40 – 50 years. Edward Jenner 1749-1823 • Used cowpox exposure to vaccinate against smallpox. 19th Century • First use of anesthetic for surgeries. • International Red Cross was founded in 1863. • Discovery of bacterial causes of disease. • 1819: 1819: • 1865: • 1892: • 1895: First successful human blood transfusion Rene Laennec invented the stethoscope. First use of antiseptics during surgery. Discovery of viruses by Dimitri Ivanfski. X-rays discovered by Wilhelm Roentgen. • Average life span = 40 – 60 years. You name it, it happened! • 1901: ABO blood groups identified • 1920: Health insurance plans are introduced. • 1928: Fleming discovered penicillin • 1952: Development of the polio vaccine. • 1953: DNA structure described by Watson & Crick. • 1954: First kidney transplant. • 1962: First severed arm reattached. • 1963: First liver transplant. • 1964: First lung transplant. • 1968; First heart transplant. • 1970: First synthesized gene. • 1975: Amniocentesis used to diagnose birth defects in-utero. And more! Dolly Introduction of sperm into egg cytoplasm • 1978: First test tube baby. • 1981: AIDS appeared in the population. • 1982: Artificial heart is implanted in human. • 1984: HIV identified. • 1990: Gene therapy used to treat disease. • 1990’s: Human Genome The Human Genome Project Project begins • 1997: Dolly the sheep is cloned. Jarvik-7 artifical heart Potential • Gene manipulation to prevent inherited diseases/Designer babies. • Slow the aging process. • Treatment for spinal cord injuries. • Improved transplantation techniques. • Increased average life • Reduced antibiotic span to 90+ years. resistance. • Computerized body parts. • Increased cloning activities.