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Collagen Fibres Muscle Fascicule Tendon Blood vessel Bone © Pressmaster, 2015, with authorisation of Shutterstock.com Genacol Genacol collagen is a bioactive complex of hydrolyzed collagen created using a unique enzymatic process called AminoLock® Sequence Technology. This unique fabrication process developed by a division of the Genacol Group consists of improving the collagen amino acids. It is produced according to the highest biotechnological standards and complies with all government requirements. Its efficiency has been scientifically demonstrated in two published clinical studies (available on our website). Genacol® is a safe substance that provides essential elements for nutritional support of the body that are necessary to encourage the regeneration and production of collagen. Genacol collagen has shown exceptional results in the human body when used on a regular basis. Genacol Corporation Canada Inc. is a full range of natural health products meant to improve your well-being, especially that of your joints. Genacol products can help you relieve osteoarthritis of the knee or hip, back pains or those nasty little pains related to aging. We also offer topical products made up of, among other things, Arnica montana, a medicinal plant recognized for decades for its anti-inflammatory benefits. Genacol can also help you sleep better with Genacol Sleep and Joints which includes melatonin to improve the length and quality of your sleep. Also, Genacol Anti-Inflammatory use curcumins, a potent Anti-Inflammatory. © Janos Levente, 2015, with authorisation of shutterstock.com Collagen , the glue of the body! © ostill, 2013, with the authorization of shutterstock.com Collagen is present in all multi-cellular organs in our body. Collagen is the fibrous structural protein that makes up the white fibres (collagen fibres) of skin, tendons, bones, cartilage, and all other connective tissues. It is also found widespread in the gelatinous substances of the body to provide stiffening properties, such as in the vitreous humor of the eye. In other words, collagen is the natural protein that constitutes most of the body’s structural support and is the primary substance of connective tissue. It is this fibrous connective tissue that holds our body together. Collagen gives to different organs and tissues their strength and their resistance to stretching. Twenty-five percent of protein in the human body and seventy-five percent of our skin are made up of collagen. Collagen is part of the natural composition of our tendons, ligaments, joints, muscles, hair, skin, and vital organs. When there is a lack of collagen in the body, various structures and functions are affected. Weakness, fatigue, aches, pain, and an overall lack of energy are the main symptoms that can be felt from a lack of collagen. In addition, all these symptoms increase with aging. Besides its numerous structural properties, collagen serves as a main catalyst for growth and it participates in the repair of almost all the body’s tissues. Several diseases caused by aging are related to a lack of this vital protein that is collagen. When there is a lack of collagen, the risk of bad function and disease increase. The production of collagen in the body slows down insidiously with age. It starts slowing down around thirty and it diminishes considerably around fifty. A lack of collagen, or the inability to use it properly in our body, participates in the early signs of aging. acids in cartilage It has been acknowledged that a hydrolyzed collagen supplement, such as Genacoll® supplies amino acids that contribute to the production of cartilage. Cartilage is dense and flexible connective tissue that is very rich in collagen (almost 67% of its dry weight). It is found at the junction of several bones of the skeleton. It looks like rubber and absorbs the impact caused by movement. It is cool-white and smooth and about 3 mm thick. There are many kinds of cartilage; the one found in the knees or the discs between the vertebrae is very rich in fibres and contributes to resisting friction during movement. In children, we find a growth cartilage that is later transformed into bone, allowing the bone to lengthen. Cartilage is a living tissue. It is comprised of cells called chondrocytes (cartilaginous cells) that undergo production and destruction cycles to maintain the balance of cartilage. After trauma, injury or a disease such as arthritis, destruction may override production of chondrocytes. The most common form of arthritis is osteoarthritis, also known as “degenerative arthritis.” It is associated to a selective destruction of cartilage cells in joints and commonly affects the hips, knees, shoulders and spine. The lack of cartilage causes slower healing, protects less against friction between bones, which can cause pain and limit joint mobility. The main reasons of the selective destruction of cartilage cells are caused by two phenomena. Firstly, the normal aging process promotes the destruction of chondrocytes and collagen is therefore reduced. Secondly, sometimes fragments of cartilage break off and end up in the fluid of the joint. The immune system then recognizes this and causes an inflammation and attacks the cartilage, thus promoting its degeneration. of composition cartilage 67% Collagen 32% Other 1% Glucosamine © JWarren Goldswain, 2013, with the authorization of shutterstock.com Importance of amino The role of collagen ligaments in © Monkey Business Images, 2013, with the authorization of shutterstock.com Ligaments are short strands of fibrous connective tissue rich in collagen (almost 80%), representing an extremely solid structure with multiple functions. Among other functions, ligaments connect bones across joints, but they do not attach bones to muscles, as tendons carry out this function. Certain ligaments are responsible for joint stability, avoiding false movements. This protects the integrity of joints when there is a sprain, and prevents dislocations when there is a forced movement (hyperflexion or hyperextension). Notably, there is a complex system of eight ligaments that reinforces the knee bones to form a very resistant joint capsule. Ligaments also serve to attach several organs to the abdominal wall and join other organs with each other, such as the stomach and the spleen. Moreover, ligaments are very important for the action of chewing food, enabling and facilitating the movement of teeth and jawbones. As collagen decreases with age, our ligaments lose their resistance and their flexibility, which can cause a frequent sensation of stiffness in our joints. Ankles, knees and wrists are the most vulnerable joints in terms of ligament injuries and common sprains. These are generally caused by stretching or tearing one or more joint ligaments. The major symptoms of a sprain are pain, swelling and difficulty to move the joint. © Maridav, 2015, with authorisation of Shutterstock.com Genacol Original Formula Active ingredients: 400 mg of hydrolyzed collagen per capsule. Dosage : Take 3 capsules daily, at night before bedtime. Genacol Original Formula is a bioactive hydrolyzed collagen complex whose efficacy has been scientifically demonstrated in two clinical and published studies. (available on our website) Genacol is a safe substance that provides the elements necessary to support the body in terms of nutrition and help it promote collagen formation. Plus, Genacol Original Formula is a supplement that contributes to the formation of connective tissue and helps reduce joint pain associated with osteoarthritic conditions. Genacol Original Formula allows for exceptional results in the human body when used on a regular basis. Our unique formula is made up of a complex of several amino acid sequences that have been produced using the AminoLock® Sequence Technology, developed exclusively by the Genacol Canada Corporation Inc. We recommend the Genacol Original Formula and Genacol Optimum for people that: • wish to reduce joint pain related to osteoarthritis; • wish to maintain healthy joints; • suffer from joint pain (knees, hips, fingers, etc.); • suffer from limited movement; • have a disease that brings about inflammation of the joints; • suffer from a sports related injury; • suffer from overworked joints; © Maridav, 2015, with authorisation of Shutterstock.com Genacol Optimum Active ingredients: Glucosamine sulfate (Crab and shrimp exoskeleton) 1500 mg Genacol® Collagen AST – Hydrolyzed collagen from bovine source 1200 mg Chondroitine sulfate 500 mg MSM (Méthyle Sulfonyl Méthane) 400 mg Dosage : Take 1 tablespoon (15 mL) with water or juice once a day. Genacol Optimum is an improved, enhanced liquid formula that helps reduce joint pain associated with arthrosis/osteoarthritis. This high-quality natural product contains a combination of 4 natural ingredients essential to the maintenance of joint health. AminoLock® Collagen (Regenerator): This collagen is manufactured based on AminoLock® Sequence Technology exclusive to Genacol. The purpose of this technology is to improve the effectiveness of collagen in fighting joint pain. Glucosamine (lubricant): Play an important role in maintaining the health of cartilage and all joints. Chondroitin Sulfate (protector): Chondroitin sulfate is a cartilaginous matrix component. Its function is to maintain osmotic pressure by absorbing water and helping to hydrate cartilage. MSM (catalyst): The sulfur contained in MSM helps to maintain immune function and keep connective tissue, such as tendons, ligaments and collagen, in good condition. © Maridav, 2015, with authorisation of Shutterstock.com Genacol Sleep Active ingredients: 3 mg of melatonin and 400 mg of hydrolyzed collagen per capsule. Dosage : Take 3 capsules, once a day, 30 minutes to 1 hour before going to bed. Combining the benefits of our scientifically proven collagen to help relieve joint pain associated with osteoarthritis and melatonin to help improve the quality and length of sleep, Genacol Sleep, will definitely help you sleep better. The consequences of a lack of sleep on our health are many and well documented over a period of several years. The body and spirit need this restful break during the night to assimilate and classify all of the new notions and information received during the day. Furthermore, a lack of sleep can cause several serious problems including: irritability, careless mistakes, concentration problems, slow reaction time and increased stress levels. Nearly 25% of Canadians suffer from insomnia and 10% suffer from osteoarthritis. We recommend Genacol Sleep for people who: • have sleep problems; • have light non-restorative sleep; • have sleep problems due to jet lag; • have variable work hours; • suffer from joint pain or osteoarthritis (knees, hips, fingers, etc.); • have a disease that causes inflammation of the joints; • have a sports related injury. Genacol Plus Active ingredients: 500 mg of glucosamine and 400 mg of hydrolyzed collagen per capsule. Dosage : Take 3 capsules once a day, in the morning when getting up. Genacol Plus is made up of a bioactive complex of Genacol hydrolyzed collagen and glucosamine hydrochloride to help maintain joint health. In addition to maintaining healthy cartilage, Genacol Plus improves the quality of synovial fluid. Because the production of collagen and glucosamine diminishes with age, the Genacol Plus supplement is important for people suffering from joint disorders. The synovial fluid lubricates and nourishes joints, particularly the elbows, knees, shoulders and hips among others. We recommend Genacol Plus for people who: • wish to maintain healthy cartilage; • suffer from joint pain (knees, hips, fingers, etc.); • suffer from limited movement; • have a disease that may cause inflammation of the joints; • suffer from a sports related injury; • suffer from overworked joints. Genacol Anti-inflammatory © Maridav, 2015, with authorisation of shutterstock.com Genacol Active ingredients: 300 mg of Curcuma Longa Rhizome and 100 mg of hydrolyzed collagen per capsule. Dosage: Take 1 to 2 capsules a day. Genacol Anti-inflammatory is a revolutionary and 100% natural anti-inflammatory that contributes to reducing inflammation and relieves joint pain. Genacol Anti-inflammatory contains curcuma and according to research, this ingredient is a safe bioactive element that is recognized for its powerful anti-inflammatory properties. Genacol Anti-inflammatory is a natural solution that carries no undesirable long-term side-effects such as those of pain killers! The Genacol Anti-inflammatory active ingredients have revolutionary and efficient properties that target inflammation and relieve pain. This undoubtedly contributes to improving the quality of life and physical condition. Genacol offers natural and effective alternatives to live without pain and improves health. Genacol Anti-inflammatory is mild and safe for the stomach as are all of the Genacol brand products! The next time that you feel pain, use Genacol Anti-inflammatory, a natural and efficient choice. For optimal results, we recommend using the product for a minimum of 2 to 6 weeks. Optimal Results 1 2 3 4 5 WEEKS OF DAILY USAGE We recommend Genacol Anti-inflammatory for people who: • have a disease that may cause inflammation of the joints; • have a sports related injury; • have overworked joints. 6 Genacol Instant Active ingredient : Arnica montana L. (Asteraceae) (Flower extract) 5%. Dosage : Apply on the affected area as needed. Genacol Instant is a natural high-quality topical gel that contains extracts of Arnica and Genacol microbeads. When gently massaging the sore area with Genacol Instant, the ingredients contained in the product help with fast and deep relief of muscle and joint pain. One of the ingredients used in Genacol Instant, Arnica, is a plant that has been used for decades throughout Europe, to help relieve pain. Clinical studies have shown comparable results to that of anti-inflammatory products available on store shelves. It is used to relieve pain and inflammation of muscles and joints (ex., sprains, bruises and joint pain). Genacol Triple Action Active ingredient: Arnica montana L. (Asteraceae) (Flower extract) 10%. Dosage: Apply a dose on the affected area, 3 to 4 times a day. Genacol Triple Action is a topical anti-inflammatory in spray form. Genacol Triple Action contains, among other things, 10% Arnica, a popular medicinal plant used for decades for the relief of stiffness, inflammation and muscular pain. This topical anti-inflammatory product in spray form penetrates deep in the skin for fast relief of chronic or temporary pain. Practical and easy to use, it has a pleasant wintergreen scent that dissipates rapidly. Moreover, it doesn’t leave fatty residue on the skin, doesn’t have any known side-effect and provides fast relief when and where you need it most! We recommend Genacol Instant & Genacol Triple Action for people who: • are looking for quick relief of pain and inflammation of muscles and joints (such as sprains, bruises and joint pain). “I have been using the Genacol® Original Formula since 2004. When I started using it, I quickly noticed a difference. Having a knee injury that required surgery, I was able to continue carrying out regular activities without difficulty. The results pushed me to become a spokesperson for Genacol and I talk about it to a lot of people. I am pleased to see people come back to thank me for having recommended the product. My wife, who suffered from tendonitis of the arm, has no more pain. I encourage people suffering from osteoarthritis or joint pain to take this fantastic Canadian product. Congratulations and thank you Genacol! Yvan Cournoyer Professional Canadian hockey legend 1-888-240-3002 | genacol.com | /genacol All reproduction is expressly prohibited under penalty of prosecution.