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Challenges in Latin America for Implementing a Biorisk Management Agenda Leila Macedo, Ph.D. www.anbio.org.br www.anbiojovem.org.br BWC, Green Cross Meeting, Geneva, Dec. 2015 Founded in 1999 The Global Biosafety Network • Today, IFBA’s global network has grown to 36 Member Biosafety Associations Globalization, World Flights and EID Overview of EID Globalization 15.179 km of borders CDC, 2014 Globalization and Emerging Diseases Dengue Socio-economic Impacts of EID • • • • Impact on Employment Impact on Economy and Global Trade Fall in consumer confidence Reduction of basic supplies like food, feed and medicines • Impact on Delivery of Health Care • Impact on Transport, Travel, Tourism, and Social Gatherings Factors Contributing to Emerging Infectious Diseases Economic Impact of EID in the Americas Pandemic flu in the US (projected):The estimated economic impact of Pandemic Influenza would be US$71.3 to $166.5 billion, excluding disruptions to commerce and society. Cholera in Peru:The outbreak of cholera in 1991 cost the Peruvian fishing industry an estimated $775 million in lost tourism and trade because of a temporary ban on seafood exports. SARS in Canada: Research suggests a loss in national economic activity in 2003 of roughly $1.5 billion, representing 0.15 percent of Canada’s real GDP. Real GDP in the City of Toronto itself was lowered by $950 million, or 0.5 percent, with about $570 million of this total concentrated in the travel and tourism sector. Origin of Infectious Disease Threats Globalization Travel Commerce Naturally Occurring Biosafety Negligence Ineffective practices Accidents Accidentally Occurring Emerging Endemic Re-emerging Biosecurity IDT Bioattack (Insiders) Weaponized or simple Mimic natural occuring Deliberately Occurring Rapid Spread of Emerging Virus and New Threats Chikungunya Virus Pillars of Biorisk Management Life Sciences Laboratories Training Biorisk Management Health Care Network and Intelligence Coordination Response Surveillance What skills are needed? Emergency Response Infectious diseases Public Health Biosafety & Biosecurity Regulatory Framework Epidemiology International Expertise Laboratory Information Management Multiple expertise needed ! Laboratories as source of Biorisks Possible Risks and Biothreats: Accidents of lab personnel Environment and healthepidemics (human and animal) Bioterrorism (att. Insiders) Economic impacts Impact in R&D Natural disasters Survey of BSL3 Labs Figure 1. The results of a survey conducted by ANBio about the state of biosafety and biosecurity in biological research institutions across LA. The survey took place from May 2008 to February 2009, and 237 questionnaires were received. (Published by NAS, 2011) Different Adequacies of Facilities Unsecured Containment Laboratories • These dangerous biological materials are not always well secured within the “BSL3 containment laboratories” Unsafe Laboratories • Is Funding Available for? Managing Geographic Challenges Year 1952 Suspect Ebola Case Pará 5,577km Paraná 1,196 Km Year 2000 Rio de Janeiro Some Gaps to Build a Sustainable BRM Agenda in Brazil • Lack of existing Liability Measures: Biosafety Law just for GMOs and non-enforcement required for other risks (Internal rule 585, 2013 from Ministry of Defense for Mass Events); anti-terrorism law in discussion; • Lack of long term plans for Biosafety and Biosecurity, including governmental funding for sensitive projects; • Lack of national or institutional systems for accidents notification with biological materials; • Weak surveillance system for infectious diseases and emergency response; • Lack of Certified Biosafety Professionals; • Inexistence of surveys/update of biological materials, destruction of samples and lab’s condition; • Weak Coordination among various stakeholders. Leadership is key to Build The Biosafety Culture (www.anbiojovem.org.br) 2015 More than 70.000 high school students in all states of the country We can’t Underestimate the Risk Microbes Do Not Respect Borders Cooperation is the only way for a safe world