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TeAMS Embryo Exam 2010 1. The choroid plexus develops in all locations except: a) LATERAL VENTRICLES b) 3RD VENTRICLE c) Aqueduct of Sylvius d) 4TH VENTRICLE 2-4 Match the following: a. Growth factor b. Transcription Factor c. Cell membrane protein 2. FGF 8- a 3. Brachyoryl T - b 4. E- Candherin – c 5. Which of the following is a myogenic transcription factor? )aSHH )bMyf5 )cMyt5 )dOtx3 6. Sensory epithelium of the skin is derived from? a) Surface ectoderm b) Neuroectoderm c) Neural crest cells 7. Which factor determines if the development of the brain will turn into midbrain or forebrain? )aSHH )bBMP4 )cHox )dFoxG1 – Otx2 8. All of the following are examples of genomic imprinting except? )aAngelman Syndrome )bPrader Willi Syndrome )cHydatidiform Mole )dPlacenta Previa 9. Which of the following structures closes first? a) Ductus venosus b) Ductus arteriosus c) Foramen ovale d) IVC 10. Which of the following structures come in contact with maternal blood? a. synctiotrophoblast b. cytotrophoblast c. endothelium d. chorion 11. What's the source of the cilliary body? .apars ceca (retina .bpars optica retinae .cintraretinal space ahal ohs td a .21woman two to three months before she gets pregnant in order to avoid birth defects? A. Folic acid 13. What happens in pulmonary valve atresia? A, Left atrium is smaller b. ductus arteriosus remains patent c. Very narrow aorta d. Closed ductus areriosus 14. Which Congenital Disease is another name for "Caudal Dysgenesis:? A. Amelia B. Meromelia C. Phocomelia D. Micromelia E. none of the above 15. Which one is formed last? a. Primitive Streak b. Trophoblast d. Epiblast e. Hypoblast 16. The allantois forms from a fold in the: a. Endoderm b. Mesoderm c. Ectoderm d. Exoderm 17. Which of the following is derived from the primitive node? a. Notocord 18. Where are the 4 colliculi both superior and inferior developed from? a. dorsal mesencephalon 19. How many Cotydelins in mature placenta at birth? a. 5-10 b. 15-20 c. 60-80 d. 100-150 20. Connexins are found in: a. SAMS b. CJMs (cell junction molecules) c. CAMS d. TAM or JAM 21. Which of the following can cause incomplete closure between the 2 ventricles? a. incomplete closure of muscular septum b. incomplete closure of membranous septum c. both - possible d. neither 22. Which of the following is/are true about aqueous humor? a. circulates from posterior to anterior chamber of the eye b. It supplies avascular tissue of eye c. It enters the blood circulation d. flows through sinus sclera e. all of the above 23. Loss of the SRY gene changes the response all of the following except? a. sertoli cells b. leydig cells c. mullerian ducts and its derivatives d. descent of the testicles e. external sexual organs 24. All of the following can result from a defect in shh except? a. cyclops, b. abnormal finger development - ? c. abnormal finger development - ? d. Increase in motor neurons 25. All of following are part of the urinary collecting system except? a. renal pelvis b. minor and major calyces c. ureter d. ureteric bud e. distal convoluted tubule 26. Picture of the embryo with a,b,c,d and asked which structure ends up most lateral upon formation of body wall (don't remember the actual choices) a. notocord b. lateral mesoderm c. somite c 27. Forelimbs usually form at somite 16 where HOX C6 works there and posterior. What happens if HOX C6 starts acting only at somite 18 and posterior? a. limb will stop developing b. limb will develop at someite 18 c. Limb will develop normally 28. On the primitive streak, a green drop is placed anterior (closer to node) than a red drop… later? a. the green drop will be found more medial 29. Where is the location of the spiral ligament? Ligament which connects to the lateral wall of cochlear duct 30. What is the embryological origin of the secondary palate? a. first brachial arch b. second brachial arch c. premaxilla d. first pharyngeal pouch e. first pharyngeal cleft 31-36 Match the following (timing of events) In that same part they asked about 400 2 36 74 28 22 31. Time in days need for a whole cycle of spermiogenesis? 74 32. How many days is a womens menstrual cycle? 28 33. How many millions of primary oocytes that exist at birth? 2 34. How many hundreds of thousands of primary oocytes at puberty? 400 35. Time in days which primary spermatocytes exist in prophase of the first meiotic division? 22 36. Time in hours from peak of LH surge until the start of ovulation? 36 37. The process of sprouting occurs during... a. Spermatogenesis b. Vasculogenesis c. Angiogenesis d. Oogenesis 38. Thyroglossal cysts are most likely to be found where? (really dont remember the options) a. behind hyoid bone b. parathyroid? c. thyroid?? d. something in the region of the mandible or maxillary bone? 39. Which doesn't form from the diencephalon? a. cerebellum b. optic vesicles c. thalamus d. hypothalamus 40. The embryological origin of bony skeleton of the face is a. Paraxial mesoderm b. Intermediate mesoderm c. Endoderm d. Lateral plate mesoderm e. Neural crest (Neuroectoderm) 41. Which of the following tubes develop last? a. gut tube b. single heart tube c. neural tube d. Notocord 42. If a bead containing nodal protein is placed on right side of an embryo after the beginning of gastrulation, what do you expect to see? b. left isomerism 43. The defect in which layers of the brain AND ventricles fall out of the skull is called? a. meningocele b. meningoencephalocele c. meningohydroencephalocele 44) Normal target motor neuron is the biceps muscle in the arm. If biceps muscle precursor cells are removed before the axon of the motor neuron has begun to extend from neural tube, what most likely happens to the motor neuron? a. motor neuron will die b. It will extend toward the bicep but stops growing, c. It will continue growing without direction d. the axon of the motor neuron will enter forelimb and reach place where biceps was supposed to be and will then make connection with the closest muscle 45. CSF drainage occurs in which? a. second ventricle b. third ventricle c. fourth ventricle d. first ventricle 46. All influence the development of muscles in the ventral lateral lip (VLL) except a. Shh b. FGF's c. MyoD d. Wnt 47. Ureteric bud penetrates into: a. Metanephric blastoma 48. Inner ridge of spiral limbus a. Epithelial cells derived from collecting duct bind to tectorial membrane 49. Epaxial muscles are Innervated by dorsal primary rami 50. Question about isomerism a. Right isomerism b. Left isomerism c. Situs inversus d. Situs solitus 51. what/where is the inner ridge located 52. Another name for the anchoring villi of placenta? a. secondary villi b. stem villi c. terminal villi 53. Question about where are the suspensory ligaments in the ear 54. Ventricular septal defects are usually result of problems in development of a) membranous portion of Interventrcular septum b) muscular portion of Interventrivular septum c) both A and B d) neither A or B are correct 55. something about a forelimb vs a hindlimb and dont remember if it was Shh or AER or Tbx usually induces hindlimbs posteriorly, but if placed where forelimb is, what happens? --> a leg at the arm position, an arm more posterior, an arm more anterior, no limb grows,... 56. All of the following are derived from mesoderm except a. Hepatocytes of the liver 57. Which statement is true about straited muscle a. Myoblasts fuse to form multinucleated muscle 58. All of the following are true regarding AD PKD – Autosomal Dominant Polycystic Kidney Disease except: a. There is more frequent involvement of the left kidney than the right kidney b. There can be elevated blood pressure c. There can be aneurisms in blood vessels d. There can be cysts in the liver, pancreas, prostate e. Approximately 50% of patients develop end stage renal failure by the age of 60 59. Which is NOT a consequence of Mullerian duct anomaly a. Uterus myomatosus b. Uterus bicornis c. Uterus didelphis d. Uterus spetatum 60. In the defect Pulmonary Valvular Atresia, one finds the foramen ovale remains open 61. Lining of external auditory meatus is derived from Ectoderm 62. The origin of the Internal Brachial Fistula is Cervical sinus 63. The 2nd, 3rd, and 4th pharyngeal arches Fuse with epicardial ridge to form smooth neck Leave behind an epithelial lined space, the cervical sinus Fuse with remains of the first brachial arch All of the above 64. Primary lens fibers Are derived of surface ectoderm 65. Which statement is incorrect Enchondral ossification occurs in sutures and fontanelles after birth 66. The discrepancy between size of newborn face and size of neurocranium attribute to Small jaw size Absence of paranasal … All of the above 67. Scaphoucephaly anomaly includes Early closure of sagittal suture, skull shape: long and narrow 68. Which statement is true Upper limbs rotate 90 degrees laterally, lower limbs rotate 90 degrees medially 69. in a strong loss-of-function mutant of Lmx1, you might see all the following problems in the development of the hand except: d. loss of fingerprints 70. the cardiac defect double outlet right ventricle occurs because: c. the aortic outflow tract does not move sufficiently leftwards to make proper contact with left ventricle 71. which tissues does not contain a component derived from the neural crest? b. the occipital bone of the skull 72. which of the following is not correct? d. the proximal-distal axis of limb is regulated by a Hox gene gradient 73. the first neurons to differentiate in the cerebral cortex are found in: b. inner cortical plate 74. a woman is taking acutane for acne. the active ingredient in it is retinoic acid. if she becomes pregnant while taking the drug, which can happen to the heart of her fetus? a. loss of ventricle tissue 7. if remove AER from forelimb bud and replaced it with AER from a hindlimb bud, what do you expect to happen? b. forelimb continues to grow and develop normally