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Transcript
The Vision
Information for supporters from Legacy Devers Eye Institute
Inside this issue
Helping people to see is very gratifying
A story of faith,
family and joy. . . . . 2
By James T. Rosenbaum, M.D., chief of ophthalmology
Treating dry eye
disease. . . . . . . . . . . . 3
Telemedicine aids
eye screenings. . . . . 4
Emanuel clinic is
thriving. . . . . . . . . . . 5
New physicians
and fellows. . . . . . 6, 7
Publications, honors
and awards, invited
lectures . . . . . . . . 8–11
Summer 2014
People sometimes wonder,
paid. He learned that he could earn a living
“Do you like being a physifor doing something that could make him feel
cian?” Or they ask a slightly
good. What could be better?
different version of the
Medicine has changed dramatically in many
same question, “Would you
bureaucratic ways since my dad graduated
want your daughters to be
medical school in 1939. But maybe the biggest
physicians?” Sometimes the
change of all is how successfully we can treat
James T.
questioner appends “today,” or
diseases, some of which are potential causes of
Rosenbaum, M.D.
asks, “Would you want your
blindness.
daughters to be physicians today?” — a slight
Devers as an institution is the realization of
change that recognizes how much medicine has
what my father learned as an individual. Helpchanged. I come from a family
ing people to see is very, very
of physicians: my father, my
gratifying. We do this one
Helping people to see is
brothers, my wife, both our
patient at a time in the clinic;
very
gratifying.
We
do
it
daughters. So I do have some
we do it for many at the
for
one
patient
in
the
clinic,
perspective on doctoring.
research bench; we do it for
for
many
at
the
research
My father wrote a famous
the next generation when we
book about being a physician.
teach. We cannot do it withbench, for the next generaInitially the book was pubout our patients. We cannot
tion when we teach. We
lished as “A Taste of My Own
do it without our patrons,
cannot do it without our
Medicine.” It was his story of
who have generously suppatients or our patrons.
battling cancer at age 70 after
ported our ability to provide
a lifetime of caring for others.
care for those who cannot
The book was retitled simply, “The Doctor.”
afford it, and who support our mission to purDisney bought the rights to the book and made
sue the discovery of new knowledge.
a movie that starred William Hurt. TwentyInside the second issue of The Vision you will
three years after its release, the book or movie
learn about some of our endeavors to extend
are required reading or viewing at medical cenwhat we can accomplish. You’ll learn about a
ters around the world.
blind patient who dedicates her life to inspirI tell you about my dad’s book because near
ing others, a new clinic in an underserved area
the start, he tells the story of one of his first
of Portland and new technologies. The staff
experiences as a physician. He made a house call
at Devers derives gratification from helping
and helped someone get well. Helping someone
patients see. Thank you for reading our newsletwith health is a gratification that is virtually
ter and giving meaning to our quest.
impossible to top. But then as a bonus, he got
The Vision ~ Summer 2014
2
Uveitis patient Joy Ross discovers what is truly important
However, as we mentioned
before, Joy is a stubborn sort,
and she set her mind to working
harder to regain herself and raise
her children.
They needed her.
Daughters Isabella (now 11) and
Georgianna (now 8) both were
diagnosed with juvenile arthritis.
‘I learned to cope’
Isabella suffered with swelling
The first thing Joy tells people
in her joints; her vision was not
when she meets them is that she
Joy Ross with her daughters, Georgianna
affected. Georgianna had the
is blind. In part, because it can be and Isabella
opposite — her joints were fine
difficult to detect her blindness.
but she was diagnosed with uveitis, which can lead
She wears life-like prosthetic shells over her natural
to a loss of vision.
eyes and carries herself with the kind of spirit and
Joy knew whom to call. She had begun receiving
attitude of someone who knows where she is going.
care from Jim Rosenbaum, M.D., chief of ophthal“If you tell me that I can’t do something, that gives
mology at Legacy Devers Eye Institute and an
me more reason to do it,” she says.
expert in uveitis. In 2000, her care under Dr. RosenJoy was diagnosed at age 3 with juvenile onset
baum was interrupted when the family moved to
arthritis. Children with arthritis can sometimes
Texas, but it resumed when they returned to Oredevelop uveitis — an inflammation of the inner
gon. She quickly involved Dr. Rosenbaum in caring
parts of the eye that can lead to a loss of vision.
for her daughters. “We love him so much,” Joy says.
Through childhood, Joy lost more sight. “The
Through Legacy Devers, along with treatment for
best I can ever remember seeing was only in one
juvenile arthritis through Randall Children’s Hospieye, the big “E” at the top of the eye chart,” says Joy,
tal at Legacy Emanuel, the girls are doing well. The
now 36. “In elementary school, it was enough to see
future seems promising. “The treatments have
shapes and colors. But it was everything I knew, so I
im­proved since I was a kid,” Joy says, noting that
learned tricks, learned to cope.”
Georgianna has not lost vision despite having uveitis.
Joy Ross has quite a story to tell.
A story of faith and family. Of
happiness and hope. Of medicine,
caring and, well, joy.
It’s a story about what life is
really about. “I have found true
happiness,” Joy says. “I discovered
what is truly important.”
A dark curtain
Fast forward several years into a life with a marriage
and two small daughters, and Joy is in Disneyland
at Christmastime. “The most magical place, the
most magical time,” she recalls. “Then, it was surreal; a dark curtain came over me.”
At age 30, Joy had lost all of her vision; the retina
had detached because of all of the years of uveitis.
“It was the death of my life as I knew it,” she says. “It
was hard for me; I had to re-find my independence
to be a mother and a wife.”
A new life
After receiving a guide dog, Joy helped start a group
called Mommies with Guides. She has found a
purpose and a passion — in raising her children and
helping others to live with blindness.
“Our faith in God helped us,” Joy says. “We are
just so thankful. I have the most amazing family, so
many blessings that it makes my life so special. And
being blind helped me discover those blessings. I
discovered what is truly important.”
3
By Peter Veldman, M.D.
Dry eye disease is one of the most common ocular
conditions and a cause of significant symptoms,
ranging from mild discomfort and redness to pain,
light sensitivity and decreased vision. Many factors
can cause dry eyes, including decreased tear production, increased tear evaporation, inflammatory
conditions, medications, age and climate, among
other causes.
The Cornea Service at Legacy Devers Eye Institute has extensive experience in the assessment,
diagnosis and management of dry eyes. They may
recommend lubrication with artificial tears, blood
serum drops, anti-inflammatory therapy, plugs in
the tear drains or surgery to permanently close the
tear drains. Fish oil, flaxseed oil and increased water
intake can be helpful as well.
Also, we are currently enrolling patients in a
multi­center phase 2 clinical study, evaluating a
testosterone ophthalmic emulsion versus placebo in
This picture of the cornea, taken using a green diagnostic
dye, shows areas of dryness in the lower half.
the management of meibomian gland dysfunction,
a common contributor to eye dryness.
If you are experiencing symptoms of dry eye disease such as redness, tearing, grittiness, sensitivity or
vision changes, please call 503-413-8202 to set up
an appointment for an evaluation.
JoAnne Fraser is retiring after 24 years at Legacy Devers
JoAnne Fraser, certified ophthalmic technician, is retiring in June
after 24 years of working at Legacy
Devers Eye Institute in the Glaucoma Department. The University
of Minnesota certified her as an
JoAnne Fraser,
ophthalmic technician in 1969. She
COT
worked in remote Alaskan villages
for two years in the early ’70s and then migrated to
Portland. She has been an ophthalmic technician
for 45 years!
The ophthalmic technicians nicknamed her “Dr.
Fraser” because of her breadth of knowledge. She
has trained hundreds of ophthalmic technicians,
ophthalmology residents, ophthalmology fellows,
and other eye doctors in the art of ophthalmology
testing, surgery and patient education. She developed the annual Thorny Issues Ophthalmic Technician Program and has been an examiner for the
Oregon Ophthalmic Certification Program. Eye
care in Portland is spectacular, and JoAnne has
helped create this reputation.
JoAnne will spend more time with her family
(three children and eight grandchildren), backpacking, rock climbing, snowshoeing and working on
her house and garden. We are grateful to her for all
of her teaching and patient care.
The Glaucoma Department is donating $1,000
in her name to the Devers Cioffi Fellowship
Educa­tion Fund. Others interested in donating
can use the enclosed envelope or visit www.
legacyhealthgiving.lhs.org/bbis/deversgiving.
The Vision ~ Summer 2014
Not a dry eye in the house: Treating dry eye disease at Devers
The Vision ~ Summer 2014
4
Telemedicine aids screenings for diabetic retinopathy
By Christina Sheppler
Can a screening at your primary
care clinic replace your yearly visit
to the eye doctor?
Telemedicine refers to the electronic transfer of information for
the purpose of providing medical
care. It can improve access to health
care, especially for those in rural
areas. In ophthalmology, telemedicine is most often used to screen for
diabetic retinopathy.
Diabetic retinopathy (DR) is a
disease that damages the blood vessels in the eye, and it is the leading Dr. Mansberger using a nonmydriatic camera, which works without the need
for dilation. The camera provides access to diabetic eye exams and helps prevent
cause of blindness in U.S. adults
blindness in patients with diabetes.
age 20–74. DR usually progresses
significantly more likely to be screened for DR when
in stages, and people in the early stages of the discompared to those in the eye care provider group.
ease often have no symptoms. For this reason, it is
After participating in the study for two years, those
important for those diagnosed with diabetes to be
in the eye care provider group were also given access
screened yearly for retinopathy. If DR is diagnosed
to telemedicine.
and treated early, the chance of vision loss can be
Over the next three years, the percentage of pargreatly reduced. Unfortunately, only about half
ticipants screened for retinopathy in the eye care
of the people diagnosed with diabetes obtain the
provider group increased by nearly 20 percent.
annual screening.
They also found that many people do not realize
Steven L. Mansberger, M.D., has spent nearly 10
diabetic eye exams are covered by medical insurance
years investigating the use of telemedicine to improve
rather than vision insurance. This finding suggests
screening rates. Screening for DR with telemedithat patients need to know that diabetic eye exams
cine involves the use of a special camera that can
are covered by their medical benefits.
take pictures of the eye without requiring dilation
Dr. Mansberger believes that offering telemediwhen patients visit their primary care doctor. The
cine during routine visits in primary care clinics is
images are then sent electronically to Legacy Devers
a promising way to increase the number of people
Eye Institute.
screened for retinopathy.
Most recently, Dr. Mansberger partnered with the
Legacy Devers is currently working to make
Oregon Prevention Research Center at OHSU to
telemedicine available in primary care clinics at
conduct a telemedicine study with Native AmeriLegacy. This effort will make getting screened for
cans. This study was funded by the Centers for
DR easier for the patient and will aid in the goal of
Disease Control and Prevention (CDC). Results
detecting and treating diabetic retinopathy before
showed that those with access to telemedicine were
vision loss occurs.
5
By Blake Acohido, M.D., Legacy Devers Eye Institute–Emanuel
Legacy Devers Eye Institute–Emanuel
turned six months old in early May.
We developed the clinic to serve
Legacy Emanuel and its Level 1
Trauma Center, Randall Children's
Hospital at Legacy Emanuel, our
Blake Acohido,
north and northeast neighbors and
M.D.
Legacy Emanuel Medical Center
employees and their families. The
clinic has officially blossomed from
snuggly newborn to squirming
infant. It has been an exciting first
six months as we zoomed past our
Jennifer Prunty, developmental milestones. In
O.D.
addition to smiling, rolling over
and sitting up, we have seen significant growth in
the clinics of both Blake Acohido, M.D., and
Jennifer Prunty, O.D.
Outside of the clinic, we have taken strides to
build our presence in our surrounding community
— Northeast Portland. In January, Steven Mans­
berger, M.D., Dr. Acohido and Dawn Bru­nelle partnered with the Oregon Academy of Ophthal­mology
and the American Academy of Ophthalmology in a
program known as “Screening with your Legislator,”
in which they provided glaucoma screenings to
senior citizens at the Urban League’s Multicultural
Senior Center. They provided screening for 43
patients, who were all very excited to discover that
there is now comprehensive eye care available in
their neighborhood. What is more, State Representative Lew Frederick and State Senator Chip Shields
each made an appearance, taking time to chat with
patients (their constituents) as they waited to
undergo screenings.
In April, Dr. Prunty teamed up for a vision screening with the Lions Club and Casey Eye Institute to
provide eye examinations and eyeglasses to those in
need. More than 100 people were screened and provided with much-needed care.
Also in April, Dr. Prunty participated in Legacy
Emanuel Medical Center’s Stepping On program,
a community-based program aimed at reducing
the incidence of falls in the elderly. Dr. Prunty discussed vision and fall prevention, emphasizing the
importance of routine eye examinations, early treatment for cataracts, and how certain eye diseases can
increase the risk for falls. The talk concluded with
examples of how patients coping with vision loss
can reduce hazards in the home that could contribute to their risk of falling.
Community optometrists are now sending
patients to Legacy Devers Eye Institute–Emanuel
for urgent same-day evaluations, subspecialty care
appointments and routine ancillary testing.
As Legacy Devers Eye Institute–Emanuel continues in its maturation, there remain numerous developmental milestones to surpass and smile upon.
Our clinic at Legacy Emanuel’s team looks forward
to further innovation and steady growth.
To make an appointment, call 503-413-3030.
The Vision ~ Summer 2014
This new clinic is thriving: Legacy Devers Eye Institute–Emanuel
The Vision ~ Summer 2014
6
Three providers join Legacy Devers Eye Institute
Jennifer Prunty, O.D.
Dr. Prunty received her degree from
Ferris State University Michigan
College of Optometry and performed her optometric residency
with a focus in ocular disease
management at Bascom Palmer Eye
Institute in Florida. She is a fellow with the American Academy of Optometry. Dr. Prunty’s clinical
interests include glaucoma, cornea, diabetic eye care
and ocular oncology. She enjoys traveling, camping
and hiking.
Sirichai Pasadhika, M.D.
Dr. Pasadhika was born in Thailand.
He went to medical school and did
ophthalmologic training in Bangkok and was trained to be a retina
specialist in Sydney, Australia. He
completed a uveitis and surgical
internship at OHSU, a retinal degeneration fellow-
ship at the University of Illinois at Chicago, and an
ophthalmology residency in Arizona. Dr. Pasadhika
is married and has two children.
Ashley Hayden, M.D.
Dr. Hayden, a native Oregonian,
graduated from Lakeridge High
School and continued on to Yale
University. She received her medical degree from the University of
Southern California and completed
her ophthalmology residency at the University of
Washington in 2011. She returned to Portland to be
close to family, and worked with Dr. Rosenbaum
at Casey Eye Institute to further her understanding
of the diagnosis and treatment of uveitis. She joins
the ophthalmology group at Legacy as a volunteer,
and will continue her working relationship with the
uveitis service. She has two boys and tries to take
them skiing as often as possible.
Save the date • Save the date
Legacy Devers Eye Institute presents
Thorny Issues in Ophthalmology
Goes to the Movies
(cornea, glaucoma and oculoplastics)
A medical education conference for ophthalmologists and optometrists
Sept. 19–20, 2014
Legacy Emanuel Medical Center • Lorenzen Auditorium
2801 N. Gantenbein Ave., Portland
An ophthalmic technician program will take place on Friday, Sept. 19.
For more information email [email protected] or call 503-413-6540.
7
Eliesa Ing, M.D.
Dr. Ing is coming on a fellowship after completing
three years of service in Landstuhl, Germany, as
a comprehensive ophthalmologist in the United
States Air Force. She completed her residency
training at the University of Texas Health Science
Center at San Antonio and medical school at the
University of Vermont College of Medicine in
Burlington. Dr. Ing is interested in glaucoma surgical treatments and newly emerging technologies to
diagnose and track disease. She enjoys long-distance
running and is excited to be back in her home state.
Shivali Menda, M.D.
Dr. Menda is originally from Seattle, Washington.
She went to medical school at Oregon Health &
Science University and completed an ophthalmology residency at University of California, San
Francisco. She is excited to be back in Portland to
pursue a glaucoma fellowship. Her hobbies include
spending time with family and friends, traveling
and yoga.
Christopher Sales, M.D., MPH
Dr. Sales graduated from Brown University. After
working for two years in a health policy institute at
Columbia University College of Physicians and
Surgeons in New York, he attended a four-year
dual-degree program in medicine and public health
at Tufts University School of Medicine in Boston.
As a medical student, he was awarded honors in
research after completing a one-year fellowship in
the epidemiology of ocular disease at the University
of California, San Francisco, and was inducted into
the Alpha Omega Alpha Honor Medical Society.
He interned at Harvard’s Beth Israel Deaconess
Medical Center and was trained in ophthalmology
at Stanford University, where he was recognized as
consultant of the year at both the university and
county hospitals.
As this year’s cornea fellow, Dr. Sales joins Mark
Terry, M.D., and Michael Straiko, M.D., at Legacy
Devers Eye Institute.
Amde Selassie Shifera, M.D.
Dr. Shifera was born and grew up in Ethiopia. He
attended medical school at Addis Ababa University
in Ethiopia, graduating in 1989.
After working in Ethiopia as a general medical
practitioner for 10 years he relocated to the United
States to further his training and prepare for a
career as a physician scientist. He attended graduate
school at the Albert Einstein College of Medicine
in New York and graduated with a Ph.D. in microbiology and immunology in 2007. Subsequently
he completed a residency in ophthalmology at the
University of Florida.
As an ophthalmologist, Dr. Shifera is interested
in the medical and surgical management of inflammatory and infectious diseases affecting the eye. As
an immunolgist, he is interested in conducting basic
and clinical research to gain a better understanding
of inflammatory diseases affecting the eye. His hobbies include watching sports, reading and travelling.
How to donate to Legacy Devers Eye Institute
Legacy Devers Eye Institute provides some of the
world’s best research, education and clinical care.
We are also the largest provider of free and lowcost eye care in Oregon.
We appreciate the grateful patients and donors
who support our mission of research, education
and clinical care through the Good Samaritan
Foundation. Every donation regardless of the
amount makes a difference to saving someone’s
sight.
To make a donation, contact Rena Whittaker at
the Good Samaritan Foundation at 503-413-5585
or [email protected], or visit www.legacyhealth.
org/giving.
The Vision ~ Summer 2014
Legacy Devers welcomes four fellows for 2014–15
The Vision ~ Summer 2014
8
Publications
Fortune B, Reynaud J, Wang L, Burgoyne CF. Does optic nerve
head surface topography change prior to loss of retinal nerve
fiber layer thickness: a test of the site injury hypothesis in
experimental glaucoma. PLoS One 2013. In press.
Gardiner SK, Fortune B, Demirel S. Signal-to-Noise Ratios for
Structural and Functional Tests in Glaucoma. Trans Vis Sci Tech
2013. In press.
Campbell JP, Davis S, Flaxel C, Rosenbaum JT, Lin P. Acquired
Drusenoid Deposits on Infrared Imaging as a Sign of Vitreoretinal Lymphoma. Ocul Immunol Inflamm. 2013 Sep 24. [Epub
ahead of print]
Mansberger SL. “Cataract surgery: The ‘New’ glaucoma procedure” Book chapter in Surgical Innovations in Glaucoma. Editors:
Samples and Ahmed. 2013. In press.
Estrovich I, Mansberger SL. “Does cataract extraction produce
a significant and sustained IOP reduction? When should I perform a combined procedure versus cataract surgery alone?”
Curbside Consultation Glaucoma: 49 Clinical Questions, second
edition. Editors: Heuer, Lewis, Panarelli and Gedde. 2013. In press.
Lin P, Suhler EB, Rosenbaum JT. The Future of Uveitis Treatment.
Ophthalmology. 2013 Oct 26. doi:pii: S0161-6420(13)00777X.10.1016/j.ophtha.2013.08.029. [Epub ahead of print] PMID:
24169255 [PubMed — as supplied by publisher] Related citations Select item 24143861[ ]2
Ali A, Rosenbaum JT. TINU (Tubulointerstitial Nephritis Uveitis)
Can Be Associated with Chorioretinal Scars. Ocul Immunol
Inflamm. 2013 Oct 21. [Epub ahead of print] PMID: 24143861
[PubMed — as supplied by publisher]
Rosenbaum JT. The E Coli Made Me Do It, The New Yorker,
online, November 11, 2013 http://www.newyorker.com/online/
blogs/elements/2013/11/the-e-coli-made-me-do-it.html
Shih YY, De La Garza BH, Huang S, Li G, Wang L, Duong TQ.
Comparison of retinal and cerebral blood flow between continuous arterial spin labeling MRI and fluorescent microsphere
techniques. J Magn Reson Imaging 2013. In press.
Gardiner SK, Ren R, Yang H, Fortune B, Burgoyne CF, Demirel S.
A Method to Estimate the Amount of Neuroretinal Rim Tissue
in Glaucoma: Comparison with Current Methods for Measuring
Rim Area. Am J Ophthalmol 2013. In press.
Sheppler CR, Lambert WE, Gardiner SK, Becker TM, Mansberger
SL. Predicting Adherence to Diabetic Eye Exams: Development
of the Compliance with Annual Diabetic Eye Exams Survey.
Ophthalmology. In press.
Abbott CJ, Choe TE, Lusardi TA, Burgoyne CF, Wang L, Fortune
B. Evaluation of retinal nerve fiber layer thickness and axonal
transport 1- and 2-weeks after 8-hours of acute intraocular pressure elevation in rats. Invest Ophthalmol Vis Sci. 2013. In press.
Levy-Clarke G, Jabs DA, Read RW, Rosenbaum JT, Vitale A, Van
Gelder RN. Expert Panel Recommendations for the use of AntiTumor Necrosis Factor Biologic Agents in Patients with Ocular
Inflammatory Disorders. Ophthalmology. 2013 Dec 17. pii: S01616420(13)00893-2. doi:10.1016/j.ophtha.2013.09.048. [Epub ahead
of print]
Artornsombudh P, Pistilli M, Foster CS, Pujari SS, Gangaputra
SS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT,
Suhler EB, Thorne JE, Kempen JH. Factors Predictive of Remission of New-Onset Anterior Uveitis. Ophthalmology. 2014
Mar;121(3):778-84. doi: 10.1016/j.ophtha.2013.09.041. Epub 2013
Dec 15.
Levin MH, Pistilli M, Daniel E, Gangaputra SS, Nussenblatt RB,
Rosenbaum JT, Suhler EB, Thorne JE, Foster CS, Jabs DA, LevyClarke GA, Kempen JH; Incidence of Visual Improvement in
Uveitis Cases with Visual Impairment Caused by Macular Edema.
Systemic Immunosuppressive Therapy for Eye Diseases Cohort
Study. Ophthalmology. 2013 Dec 11. pii: S0161-6420(13)00843-9.
doi: 10.1016/j.ophtha.2013.09.023. [Epub ahead of print]
Zhang Z, Liu Q, Leskov KS, Wu X, Duan J, Zhang GL, Hall M,
Rosenbaum JT. Roscovitine suppresses CD4+ T cells and
T cell-mediated experimental uveitis. PLoS One. 2013 Nov
18;8(11):e81154. doi: 10.1371/journal.pone.0081154. Erratum in:
PLoS One. 2013;8(12).
Huston RK, Markell AM, McCulley EA, Pathak M, Rogers SP,
Sweeney SL, Dolphin NG, Gardiner SK. Decreasing Necrotizing
Enterocolitis and Gastrointestinal Bleeding in the Neonatal
Intensive Care Unit: the Role of Donor Human Milk and Exclusive Human Milk Diets in Infants <1500 Grams Birth Weight.
Infant Child Adolesc Nutr 2014. In press.
Ren R, Yang H, Gardiner SK, Fortune B, Hardin C, Demirel S,
Burgoyne CF. Anterior Lamina Cribrosa Surface Depth, Age
and Visual Field Sensitivity in the Portland Progression Project.
Invest Ophthalmol Vis Sci 2014. In press.
Gardiner SK, Swanson WH, Goren D, Mansberger SL, Demirel S.
Assessment of the reliability of standard automated perimetry in
regions of glaucomatous damage. Ophthalmology. 2014. In press.
Rafael L. Furlanetto RL, De Moraes CG, Teng CC, Liebmann JM,
Greenfield DS, Gardiner SK, Ritch R, Krupin T for the Low-pressure Glaucoma Treatment Study Group. Risk factors for Optic
Disc Hemorrhage in the Low-pressure Glaucoma Treatment
Study. Am J Ophthalmol. 2014. In press.
Gritsiou Y, Hegsted DA, Schlesinger P, Gardiner SK, Gubler KD.
A Retrospective Analysis of the Effectiveness of Low Molecular
Weight Heparin for Venous Thromboembolism Prophylaxis in
Trauma Patients. Am J Surg 2014. In press.
He L, Yang H, Gardiner S, Williams G, Hardin C, Strouthidis
NG, Fortune B, Burgoyne CF. Longitudinal Detection of Optic
Nerve Head Changes by Spectral Domain Optical Coherence
9
Ali A, Ku JH, Suhler EB, Choi D, Rosenbaum JT. The course
of retinal vasculitis. Br J Ophthalmol. 2014 Feb 7. doi: 10.1136/
bjophthalmol-2013-303443. [Epub ahead of print] PMID:
24511084 [PubMed — as supplied by publisher] 24342020.
Wang L, Burgoyne CF, Cull G, Thompson S, Fortune B. Static
blood flow autoregulation in the optic nerve head in normal
and experimental glaucoma. Invest Ophthalmol Vis Sci. 2014 Feb
10;55(2):873-80
Yu J, Liang Y, Thompson S, Cull G, Wang L. Parametric transfer
function analysis and modeling of blood flow autoregulation
in the optic nerve head. Int J of Physiol, Pathophysiol and Pharmacol 2014;6(1): 13-22.
He L, Ren R, Yang H, Hardin C, Reyes L, Reynaud J, Gardiner
SK, Fortune B, Demirel S, Burgoyne CF. Anatomic vs Acquired
Image Frame Sectoral Discordance in Spectral Domain Optical Coherence Tomography Minimum Rim Parameterization
in the Portland Progression Project. PLoS One. First published
on March 18, 2014, as doi:10.1371/journal.pone.0092225 http://
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.
pone.0092225
Ren R, Yang H, Gardiner SK, Fortune B, Hardin C, Demirel S,
Burgoyne CF. Anterior Lamina Cribrosa Surface Depth, Age,
and Visual Field Sensitivity in the Portland Progression Project
(P3 Study). IOVS 2014; 55: 1531-1539. DOI:10.1167/iovs.13-13382
Pasadhika S, Rosenbaum JT. Biologics. 2014 Feb 15;8:67-81.
eCollection 2014. Update on the use of systemic biologic agents
in the treatment of noninfectious uveitis.Ophthalmology. 2014
Mar;121(3):778-84. doi: 10.1016/j.ophtha.2013.09.041. Epub 2013
Dec 15.
Keck KM, Choi D, Savage LM, Rosenbaum JT. Insights into uveitis in association with spondyloarthritis from a large patient
survey. J Clin Rheumatol. 2014 Apr;20(3): 141-5. doi:10.1097/
RHU.0000000000000087. PMID: 24662555 [PubMed — in
process].
Suhler EB, Lim LL, Beardsley RM, Giles TR, Pasadhika S, Lee ST,
de Saint Sardos A, Butler NJ, Smith JR, Rosenbaum JT. Rituximab Therapy for Refractory Orbital Inflammation: Results of a
Phase 1/2, Dose-Ranging, Randomized Clinical Trial. JAMA Ophthalmol. 2014 Mar 20. doi: 10.1001/jamaophthalmol.2013.8179.
[Epub ahead of print.]
Miller LD, Gardiner SK, Gubler KD. Emergency Department
Referral for Organ Donation: More Organ Donors and More
Organs per Donor. Am J Surg 2014. In press.
Gardiner SK. Effect of a Variability-Adjusted Algorithm on the
Efficiency of Perimetric Testing. Invest Ophthalmol Vis Sci 2014.
In press.
Kinast RM, Barker GT, Day SH, Gardiner SK, Mansberger SL.
Factors related to online patient satisfaction with ophthal­
mologists. Ophthalmology 2014. In press.
Fortune B, Reynaud J, Cull G, Burgoyne CF, Wang L. The effect
of age on optic nerve axon counts, SDOCT scan quality and
peripapillary retinal nerve fiber layer thickness measurements
in rhesus monkeys. Translational Vision Science & Technology.
2014. In press.
Honors and awards
Jim Rosenbaum, M.D., was honored by the American College
of Rheumatology with its Distinguished Clinician Scholar Award.
The award was presented at the annual meeting of the ACR.
One honoree is selected per year. This award is considered one
of the highest honors from the ACR. He is the first Oregonian
to receive the award. The honor was given for his career-long
efforts to understand the relationship between inflammation
in and around the eye and inflammation elsewhere in the
body. San Diego, Calif., Oct. 26, 2013
Jim Rosenbaum, M.D. — The Rosenbaum lab has received
funding from Auventx Pharmaceuticals to study a novel topical
approach to treating uveitis in an animal model.
Steven L. Mansberger, M.D., MPH, received two awards in
November 2013 “Best Doctors in America, 2014” and the American Academy of Ophthalmology, State Society Award, “Free
glaucoma screenings with your legislator.”
Steven L. Mansberger, M.D., MPH, was added as an executive
editor in epidemiology for the American Journal of Ophthalmology. November 2013.
Steven L. Mansberger, M.D., MPH, was named a Scientific Advisor for the Glaucoma Research Foundation to review research
grants. November 2013.
Steven L. Mansberger, M.D., MPH, has been appointed a member of the Academy’s EyeNet Editorial Advisory Board.
Steven L. Mansberger, M.D., MPH, was named to Good Samaritan Foundation Board of Directors.
Steven L. Mansberger, M.D., MPH, has been appointed as a
consultant for the American Academy of Ophthalmology Preferred Practice Pattern-Glaucoma Panel.
Steven L. Mansberger, M.D., MPH, was invited by the American
Board of Ophthalmology (ABO) to be part of their eightmember Exam Development Committee. This committee
writes questions for the written oral board examinations for
ophthalmologists.
Steven L. Mansberger, M.D., MPH, was named Affiliate Professor
of Ophthalmology at Oregon Health & Science University (OHSU).
continues on page 10
The Vision ~ Summer 2014
Tomography in Early Experimental Glaucoma. Invest Ophthalmol Vis Sci 2014; 55:574-586.
The Vision ~ Summer 2014
10
Honors and awards (continued)
Brad Fortune, O.D., Ph.D., began a three-year term of service in
December 2013 to the Legacy Research Institute Institutional
Animal Care and Use Committee (IACUC).
Brad Fortune, O.D., Ph.D., will serve again this year on the Program Committee for the 2014 ARVO-ISIE Conference (International Society for Imaging in the Eye).
Stuart Gardiner, Ph.D., received the 2014 Bernard Schwartz
Memorial Award, along with a $500 travel grant for presenting a paper at the American Glaucoma Society meeting in
Washington, D.C., on March 1: “Assessment of the Reliability of
Standard Automated Perimetry in Regions of Glaucomatous
Damage.”
Michael Straiko, M.D., was interviewed by the ASCRS Eye World
publication for their feature story: “DMEK experts offer pearls,
pitfalls for performing procedure.” It is in the February issue of
Eye World.
Lin Wang, M.D. In April, the National Eye Institute (1R21EY02443201 NEI/NIH) and the BrightFocus Foundation (G2014059)
awarded Dr. Wang grants to develop equipment, establish
techniques (NEI/NIH) and characterize (BrightFocus Foundation) the role of astrocytes in blood flow autoregulation as part
of the disease mechanism within glaucoma. The project period
for both is from spring 2014 to 2016, with a combined total
amount of $503,750.
Invited lectures
Jim Rosenbaum, M.D., SpondyloArthritis Research and Treatment Network meeting and lectured on the microbiome. San
Francisco, Calif. September 2013.
Jim Rosenbaum, M.D., visiting faculty member lectured to the
division rheumatology. University of Chicago, Chicago, Ill., Sept.
10, 2013.
Jim Rosenbaum, M.D., delivered the Alta lecture at the University of California on Dec. 5, 2013, in San Francisco, Calif.
Jim Rosenbaum, M.D., as a visiting professor delivered two
lectures at the Bascom Palmer Eye Institute on Dec. 16, 2013, in
Miami, Fla.
Jim Rosenbaum, M.D., lectured on “Cytokines and the Immunopathology of Uveitis” at the meeting of the International
Ocular Immunology Society on Feb. 27, 2014, in Valencia, Spain.
Jim Rosenbaum, M.D., lectured to the University of Pittsburgh
Medical Center, Division of Rheumatology on “Eye Disease for
Rheumatologists.” March 7, 2014.
Jim Rosenbaum, M.D., was a speaker and panelist for the
Cleveland Clinic Uveitis Update and spoke on “Laboratory testing to evaluate patients with uveitis.” March 8, 2014.
Jim Rosenbaum, M.D., served on two separate National Eye
Institute (NIH) review panels: one to evaluate core grants and the
other to evaluate career development awards. March 10, 2014.
Jim Rosenbaum, M.D., was a panelist in Las Vegas for Retina
Today to discuss the use of local and systematic corticosteroids
for uveitis and retinal diseases. March 15, 2014.
Jim Rosenbaum, M.D., chaired a session for the World Ophthalmology Congress on infection and inflammation, and lectured
on HLA B27, the microbiome, and uveitis. Tokyo, Japan. April 5,
2014.
Jim Rosenbaum, M.D., was a guest of the Japanese Ophthalmological Society and spoke on S10018/A49, an endogenous
TLR4 ligand, and its role in uveitis on April 5, 2014.
Claude Burgoyne, M.D., FDA meeting with Gerhard Zinser,
Ph.D., president of Heidelberg Engineering, in support of the
Heidelberg Spectralis Normative Database. Aug. 27, 2013.
Jim Rosenbaum, M.D., DGRh-Kongress — German rheumatology annual meeting, lectured at the meeting via the Internet.
Heidelberg, Germany. Sept. 19, 2013.
Claude Burgoyne, M.D., Swedish Glaucoma Society Annual
meeting: Keynote Lecture: co-delivered via the Internet with
Bal Chauhan, Ph.D.: “Paradigm Change to the Clinical Assessment of the Optic Nerve Head.” Stockholm, Sweden. September 19, 2013.
Jim Rosenbaum, M.D., Rheumatology Invitational Educational
Series (BRIESE). Invited speaker: the lectures were either on the
microbiome or the intersection between rheumatology and
ophthalmology. British Columbia. Sept. 27–28, 2013.
Claude Burgoyne, M.D., Legacy Devers Eye Institute’s Thorny
Issues in Ophthalmology: Climate Change conference. Lecture
entitled: “Cup to Disc Ratio — Soon to be extinct?” Portland,
Ore. Sept. 20, 2013.
Jim Rosenbaum, M.D., was an invited guest at Allergan’s
Inflammation and Ocular Surface Focus Group. Hamburg, Germany. Oct. 25, 2013
Claude Burgoyne, M.D., International Society for Eye Research
(ISER), Keynote Lecture: “Optic Nerve Head Connective Tissue
Deformation, Disorganization and Remodeling in Early Monkey
Experimental Glaucoma — Implications for Mechanisms.” Saratosa, Fla. Sept. 29–Oct. 2, 2013.
Jim Rosenbaum, M.D., was honored by the University of
Toronto as the Inman Lecturer. He gave four lectures on the
interface between rheumatology and ophthalmology. Toronto,
Canada. November 2013.
Claude Burgoyne, M.D., Optometric Glaucoma Society’s (OGS)
2013 Honoree at its 12th annual scientific meeting, two lectures:
“The Death of Cup to Disc Ratio in Glaucoma — SDOCT Paradigm
11
Claude Burgoyne, M.D., Heidelberg Academy Glaucoma Faculty
Inauguration at Moorfields Eye Hospital, three lectures: “Paradigm Change to the Clinical Assessment of the Optic Nerve
Head in Glaucoma.”“Clinical Implications of Lamina Cribosa
Deformation and Remodeling in Glaucoma.”“Optic Nerve Head
Biomechanics and the Clinical Prediction of Susceptibility.” London, England. Oct. 29–30, 2013.
Claude Burgoyne, M.D., gave two lectures at the American
Academy of Ophthalmology (AAO) meeting, “Spotlight on
OCT” Symposium: “Lessons from OCT Imaging of the Lamina
Cribrosa.” Heidelberg Engineering Symposium: “Paradigm
Change to the Clinical Assessment of the Optic Nerve Head in
Glaucoma.” Nov. 17, 2013. New Orleans, La.
Claude Burgoyne, M.D., ONHRL Presentation at the American
Glaucoma Society Annual Meeting. “Variability of Glaucoma
Specialists’ Rim Width Estimates and Their Accuracy Relative to
Colocalized Spectral Domain Optical Coherence Tomography
(SDOCT)” and “Glaucoma Neurodegeneration and Neurorescue
Symposium — What Role Does Aging Play.” Feb. 28–March 1,
2014. Washington, D.C.
Brad Fortune, O.D., Ph.D., attended the Glaucoma Progression
(GPS) and North American Perimetry Society (NAPS) meetings.
At the GPS meeting, Brad presented a talk entitled: “The effect
of age on optic nerve axon counts, SDOCT scan quality and
peripapillary retinal nerve fiber layer thickness measurements.”
Chapel Hill, N.C. Oct. 1–4, 2013.
Brad Fortune, O.D., Ph. D., “Axonopathy in Glaucoma: Implications for Diagnosis and Clinical Management.” Ezell Research
Symposium, American Academy of Optometry. Seattle, Wash.
Oct. 24, 2013.
Brad Fortune, O.D., Ph.D., presented an invited lecture entitled
“The effect of cytoskeletal changes on imaging,” at the third
Optic Nerve Conference. Dec. 4–6, 2013, in Obergurgl, Austria
(Tirolean Alps).
Brad Fortune, O.D., Ph.D., gave three presentations and moderated one at the annual Association for Research in Vision and
Ophthalmology (ARVO) meeting.
Invited lecture during the Glaucoma Section Minisymposium:
Symposium Title: “Mechanisms of Axonal Damage in Optic
Nerve Disease.” Lecture title: “Imaging axonal transport and
degeneration.” May 5, 2014.
Invited lecture during the “Special Interest Group” (SIG) meeting: SIG Title: “Polarization-sensitive optical coherence tomography for retinal imaging: What needs to be done to transfer the
technology from the laboratory to the clinic?” Lecture title: “Early
stage axonal cytoskeletal damage detected in vivo by polarization-sensitive imaging in experimental glaucoma.” May 5, 2014.
Session moderator for the glaucoma talks session called
“Visual Fields and Visual Function.” May 6, 2014. Primary ARVO
abstract presentation title: “Evidence of axonopathy during
early-stage experimental glaucoma: relationship between in
vivo imaging and histological findings.” May 6, 2014.
Michael Straiko, M.D., keynote address at ASETCIRC meeting.
Seville, Spain. September 2013.
Michael Straiko, M.D., Cornea Society meeting. “Reducing complications in DMEK using a novel glass injector for simplified
tissue delivery.” New Orleans, La. November 2013.
Michael Straiko, M.D., Cornea Society meeting. “Eliminating
the Possibility of Upside-Down DMEK Grafts: A Novel Stromal
Side S-stamp Technique for DMEK.” New Orleans, La. November
2013.
Michael Straiko, M.D., American Academy of Ophthalmology.
“Keratoconus in Patients With Fuchs Endothelial Dystrophy
Unmasked by Descemet Membrane Endothelial Keratoplasty.”
New Orleans, La. November 2013.
Michael Straiko, M.D., was an invited speaker at the “Kaiser Permanente Northwest Ocular Pathology 2014 Winter Conference.”
He lectured on corneal ectasia diagnosis and management
options. The talk focused heavily on the collagen cross linking
study he is conducting at Devers.
Michael Straiko, M.D., was an invited speaker at the Cleveland
Clinic Cole Eye Institute Cornea Summit in Orlando, Fla. He lectured on DMEK techniques.
Michael Straiko, M.D., was invited as the keynote speaker at the
Philips Eye Institute in Minneapolis for their annual conference.
He lectured on a variety of corneal topics.
Steven L. Mansberger, M.D., MPH, gave two lectures: “The Great
Debate in Glaucoma: For Cataract and Glaucoma Controlled
on Medication, I prefer Cataract Surgery” and “Trabeculectomy:
How to maximize your success.” Didactic course. American
Academy of Ophthalmology. New Orleans, La. November 2013.
Steven L. Mansberger, M.D., MPH, gave the President’s Lecture
at the Optometric Glaucoma Society Meeting.
Cheri Stowell, Ph.D., ONHRL Presentations at the American
Glaucoma Society Annual Meeting. “Decrease in Myelin Proteins in the Optic Nerve Head and Optic Nerve in Non-human
Primate Early Experimental Glaucoma.” Washington, D.C. Feb.
28–March 1, 2014.
Camila Zangalli, M.D., “Comparison of Spectral Domain Optical
Coherence Tomography Deep Optic Nerve Head Imaging to
Co-localized 3-D Histomorphometry.” Washington, D.C. Feb.
28–March 1, 2014.
Tammy Martin, Ph.D., was invited to chair the pre-ARVO American Uveitis Society spring meeting. May 3, 2014.
The Vision ~ Summer 2014
Change and its Clinical Implications.”“Onset to Endstage — 20
years of Monkey Experimental Glaucoma.” Seattle, Wash. Oct.
22–23, 2013.
Legacy Good Samaritan Medical Center
Legacy Devers Eye Institute
1015 N.W. 22nd Ave.
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Editors: Steven L. Mansberger, M.D., MPH, Emily P. Jones, M.D.,
Carly M. Carcione, B.S., Dana Lord
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