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Breast Disorders 1 Copyright © 2008 Lippincott Williams & Wilkins. Breast Disorders • Overview of anatomy of the breast • Cultural and psychosocial considerations • Breast cancer is a major health problem • In the U.S., more than 215,000 women and 1,450 men develop breast cancer annually, and more than 40,000 die 2 Copyright © 2008 Lippincott Williams & Wilkins. Anatomy of the Breast 3 Copyright © 2008 Lippincott Williams & Wilkins. Assessment • Health history • Physical assessment – Inspection – Palpation • Upright and supine • Axillary and clavicular areas as well as breasts – The male breast • Inspection, and palpation of axillae • Assess for gynecomastia 4 Copyright © 2008 Lippincott Williams & Wilkins. Guidelines for Early Detection of Breast Cancer • Women in their 20s and 30s: clinical breast exam at least every 3 years, then preferably annually after age 40 • Mammography annually beginning at age 40 • Women at increased risk may have earlier initial screening, shorter screening intervals, or additional screening procedures such as ultrasound and MRI • Teach women in their 20s the benefits and limitations of breast self-examination (BSE) Copyright © 2008 Lippincott Williams & Wilkins. 5 Breast Self-Examination • Provide instruction to women regarding BSE • Instructions should be provided to men if there is a family history of breast cancer • Encourage BSE but do not overemphasize it • Instructional materials can be obtained from the American Cancer Society and The National Cancer Institute 6 Copyright © 2008 Lippincott Williams & Wilkins. Lymph Nodes 7 Copyright © 2008 Lippincott Williams & Wilkins. Teaching Breast SelfExamination • Best performed days 5 to 7 days after first day of menses or once monthly for postmenopausal women • Review the feel of normal breast tissue and ways or identify changes • Routine BSE helps patients become familiar with their own “normal abnormalities” • Demonstrate the examination technique • Encourage the patient to perform a BSE demonstration on herself or on a breast model 8 Copyright © 2008 Lippincott Williams & Wilkins. Breast Self-Examination • Stand in front of a mirror • Check both breasts for anything unusual • Look for discharge from the nipple and puckering, dimpling, or scaling of the skin 9 Copyright © 2008 Lippincott Williams & Wilkins. Breast Self-Examination (cont.) • Watch closely in the mirror as you clasp your hands, bend your head, and press your hands forward • Note any change in the contour or your breasts 10 Copyright © 2008 Lippincott Williams & Wilkins. Breast Self-Examination (cont.) • Next, press your hands firmly on your hips and bow slightly toward the mirror as you pull your shoulders and elbows forward • Note any change in the contour of your 11 breasts Copyright © 2008 Lippincott Williams & Wilkins. Breast Self-Examination (cont.) • Raise your left arm; using 2 or 3 fingers, feel your left breast carefully and thoroughly • Beginning at the outer edge, press the flat part of your fingers in small circles, moving the circles slowly around the breast • Gradually work toward the nipple 12 • Cover the whole breast Copyright © 2008 Lippincott Williams & Wilkins. Breast Self-Examination (cont.) • Feel for any lumps or masses. • Repeat on the right breast; step 4 should be repeated lying down • Lie flat on your back with your left arm over you head and a pillow or folded towel under the left shoulder • Use the same circular motion 13 Repeat on the right breast Copyright © 2008 Lippincott•Williams & Wilkins. Teaching Breast SelfExamination • Part of the examination may be done in the shower with soapy hands to glide over the breast and focus on underlying tissue • Note the importance of including the area between the breast and underarm, and the underarm itself • Discuss reporting of any changes • Describe the goals, methods of instruction, and methods of evaluation for a teaching plan for BSE • List resources for information and materials Copyright © 2008 Lippincott Williams & Wilkins. 14 Diagnostic Tests • Mammography – Yearly starting at 40; earlier for high-risk women – Certified facility • Galactography – Dye injected into ductal opening followed by mammogram • Ultrasonography – Helps to distinguish fluid-filled cysts from other lesions – Good for dense breasts 15 Copyright © 2008 Lippincott Williams & Wilkins. Diagnostic tests • Magnetic resonance imaging (MRI) – Highly sensitive – Most useful with proven breast cancer to assess extent; also detects occult breast cancer • Biopsies – Percutaneous: fine-needle aspiration and core biopsies – Surgical biopsies 16 Copyright © 2008 Lippincott Williams & Wilkins. Mammography 17 Copyright © 2008 Lippincott Williams & Wilkins. Conditions affecting the nipple • Nipple discharge – May be r/t many causes, including carcinoma, papilloma, pituatary adenoma, cystic breasts, medications (including OCP) – May be normal with expression – Warrants investigation if green, malodorous, persistent, spontaneous, bloody, unilateral • Evaluated via galactogram or biopsy 18 Copyright © 2008 Lippincott Williams & Wilkins. Benign Conditions of the Breast • Mastitis – Inflammation or infection of breast tissueusually breast feeding women – Dull to severe pain in affected area, possilbe purulent discharge – Treatment is antibiotics and cold compresses 19 Copyright © 2008 Lippincott Williams & Wilkins. Benign conditions of the breast • Cysts – Fluid filled sacs that develop as breast ducts dilate; estrogen thought to play a role – Age 30-50 – Cysts usually left alone once they are confirmed nonmalignant • Fibroadenomas – Firm, movable benign tumors – Nontender, sometimes removed to r/o malignancy 20 Copyright © 2008 Lippincott Williams & Wilkins. Benign conditions of the breast • Fibrocystic changes – Characterized by excessive fibrous tissue, hyperplasia of the ductal epithelial lining, and cyst formation • Results in pain and nerve irritation • Influenced by hormones – Manifests as numerous palpable lumps - round, well delineated, movable; may be tender – Lumps change size with hormone changes 21 Copyright © 2008 Lippincott Williams & Wilkins. Breast cancer • Lifetime risk for women: 1 in 8; most diagnosed after 50 • Types – Ductal carcinoma in situ – Invasive breast cancer • • • • • • • Infiltrating ductal carcinoma (75%) Infiltrating lobular carcinoma (5%) Medullary carcinoma Mucinous carcinoma Tubular ductal carcinoma Inflammatory carcinoma Paget disease 22 Copyright © 2008 Lippincott Williams & Wilkins. Risk Factors for Breast Cancer • Female gender • Increasing age • Personal and family history including genetic mutations – BRCA 1 and 2 – 5-10% • • • • • • • Hormonal factors (nullparity, 1st child>30, HT) Exposure to radiation History of benign proliferative breast disease Obesity High-fat diet (controversial) Alcohol intake ?Smoking Copyright © 2008 Lippincott Williams & Wilkins. 23 Protective factors - breast cancer • Regular exercise • Breastfeeding 24 Copyright © 2008 Lippincott Williams & Wilkins. Prevention in the high risk patient • Long term surveillence • Chemoprevention • Prophylactic mastectomy 25 Copyright © 2008 Lippincott Williams & Wilkins. Clinical manifestions of breast cancer Most often found in the upper outer quadrant • • Lesions are nontender, fixed, hard with irregular borders • Advanced signs may include skin dimpling, nipple retraction, skin ulceration, peau d’orange QuickTime™ and a decompressor are needed to see this picture. 26 Copyright © 2008 Lippincott Williams & Wilkins. Prognosis for breast cancer • Most dependent on tumor size and whether it has spread to the lymph nodes – The smaller the tumor, the better prognosis – Most common route of regional spread is axillary lymph nodes; distant metastasis can affect any organ system – 5 year survival by staging (0-4) • I - 98% • IIIA - 56% • IV - 16% 27 Copyright © 2008 Lippincott Williams & Wilkins. Surgical Management—Breast Cancer • Breast conservation treatment – Removal of entire tumor • Total mastectomy – Removal of breasts, pectoral muscles, axillary lymph nodes, fat/adjacent tisue • Modified radical mastectomy – Remove breast and axillary nodes • Sentinel node biopsy and axillary lymph node dissection • Breast reconstruction surgery Copyright © 2008 Lippincott Williams & Wilkins. 28 Breast Reconstruction With Tissue Expander 29 Copyright © 2008 Lippincott Williams & Wilkins. Breast Reconstruction With TRAM 30 Copyright © 2008 Lippincott Williams & Wilkins. Breast Reconstruction— Latissimus Dorsi Flap 31 Copyright © 2008 Lippincott Williams & Wilkins. Adjuvant Nonsurgical Management of Breast Cancer • Radiation therapy: external beam (weeks) , brachytherapy (days) • Chemotherapy • Hormonal therapy – Estrogen and progesterone receptor assay – Selective estrogen receptor modulators (SERMs): tamoxifen – Aromatase inhibitors: anastrozole, letrozole, and exemestane 32 Copyright © 2008 Lippincott Williams & Wilkins. Nursing Process—Assessment of the Patient Undergoing Breast Cancer Surgery • How is the patient responding to her diagnosis? • What coping mechanisms does she find helpful? • What psychological or emotional supports does she have and use? • Is there a partner, family member, or friend available to assist in making treatment choices? • What are her educational needs? • Is she experiencing any discomfort? 33 Copyright © 2008 Lippincott Williams & Wilkins. Nursing Process—Preoperative Diagnosis of the Patient Undergoing Breast Cancer Surgery • Deficient knowledge • Anxiety • Fear • Risk for ineffective coping • Decisional conflict Copyright © 2008 Lippincott Williams & Wilkins. 34 Nursing Process—Postoperative Diagnosis of the Patient Undergoing Breast Cancer Surgery • Pain • Disturbed sensory perception • Disturbed body image • Self-care deficit • Risk for sexual dysfunction • Deficient knowledge – Drain management – Arm exercises – Hand and arm care Copyright © 2008 Lippincott Williams & Wilkins. 35 Collaborative Problems/Potential Complications • Lymphedema (10-30%) – Results if functioning lymphatic channels are inadequate to ensure a return flow of lymph fluid to general circulation – Different from transient edema • Hematoma/seroma formation – Collection of blood or fluid inside the cavity • Infection – Risk is higher in patients with immunosuppression Copyright © 2008 Lippincott Williams & Wilkins. 36 QuickTime™ and a decompressor are needed to see this picture. 37 Copyright © 2008 Lippincott Williams & Wilkins. Nursing Process—Planning the Care of the Patient Undergoing Breast Cancer Surgery • Major goals may include: – Increased knowledge about the disease and its treatment – Reduction of preoperative and postoperative fear, anxiety, and emotional stress – Improvement of decision-making ability and improvement of coping skills – Improvement in sexual function – Absence of complications Copyright © 2008 Lippincott Williams & Wilkins. 38 Preoperative Interventions • Review and reinforce information on treatment options • Prepare patient regarding what to expect before, during, and after surgery • Inform patient regarding surgical drain, arm and shoulder mobility, and range-of-motion exercises • Maintain open communications • Provide patient with realistic expectations • Support coping • Involve or provide information for supportive services and resources • Support patient decisions Copyright © 2008 Lippincott Williams & Wilkins. 39 Postoperative Interventions • Monitoring and managing postoperative complications – Lymphedema, hematoma, infection, as well as general complications related to surgery • Inform patient regarding common postoperative sensations • Pain management • Promoting a positive body image – Provide bra with breast form • Support coping and adjustment • Provide counseling and referral • See NCP 52-1 40 Copyright © 2008 Lippincott Williams & Wilkins. Hand and Arm Care • Potential for lymphedema formation after axilliary lymph node dissection (ALND) • Patient education • Prevention is vital; follow guidelines for the rest of life • No blood pressure, injections, or blood draws in the affected arm • Perform exercises 3X a day for 20 minutes to increase circulation and muscle strength, prevent stiffness and contractures, and restore ROM • A mild analgesic or a warm shower may be helpful prior to exercise • Initial limitation of lifting (over 5 to 10 lbs) and activity • Prevention of ANY injury and infection • May require elasticCopyright sleeve © 2008 Lippincott Williams & Wilkins. 41 Exercises After Breast Surgery Wall climbing Rod lifting Rope turning Pulley tugging 42 Copyright © 2008 Lippincott Williams & Wilkins. Drain Management • May need home care referral to assist with drain management • Drains are usually removed when drainage is less than 30 mL in a 24hour period; usually occurs in 7 to 10 days • Drain site and incision care 43 Copyright © 2008 Lippincott Williams & Wilkins. Teaching self-care • Report symptoms/signs - infection, swelling, hematoma, • Drain management • Incision care – Usually can shower and wash incision site after day 2 – May have to wait until drain is removed if present – Incision should heal after 4-6 weeks – ROM exercises until full ROM is restored (4-6 wks) • Follow up care 44 Copyright © 2008 Lippincott Williams & Wilkins. Quality of life and survivorship • Long term survivors have difficulty with issues pertaining to sexuality and menopausal symptoms – Estrogen withdrawal from chemo-induced menopause and hromonal treatments may lead to severe symptoms – Hormone therapy is contraindicated – Chemotherapeutic agents may cause impaired cognitive functioning and cardiac side effects – Long term effects of radiation may include pneumonitis – Psychological sequelae 45 Copyright © 2008 Lippincott Williams & Wilkins. Diseases of the Male Breast • <1% of all breast cancers; average age 67 years • Early detection is rare due to rarity of the disease • Signs may include painless lump beneath the areola, nipple retraction, bloody discharge, or skin ulceration • Total mastectomy is indicated, with possible adjuvant chemotherapy and radiation 46 Copyright © 2008 Lippincott Williams & Wilkins.