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Diseases in Anatomy and Physiology Unit C Essential Standard 5.00 Discuss the role of major systems of small animals. Objective 5.02 Discuss the ways that disease processes affect major body systems. Infectious Diseases of Dogs Group of diseases caused by pathogenic microorganisms – – – – – – Canine distemper Canine parvovirus infection Kennel cough Rabies Canine brucellosis Salmonellosis Canine Distemper Caused by the inhalation of the airborne virus. Symptoms: – – Early-vomiting and diarrhea Later-tremor and epileptic fits Canine Parvovirus Infection Caused by viral contact of materials contaminated with feces from infected dogs Affects mostly young pups Symptoms: – – – Vomiting Bloody diarrhea Refusal to eat Kennel Cough (Tracheobronchitis) Respiratory disease contracted in confinement (pet shops, dog shows, kennels, etc.) Symptom: – Cough Rabies Viral disease that attacks the central nervous system. All warm blooded animals can transmit rabies. Rabies Symptoms Occur 2 weeks to 3 months after bite. Severe can be within 10 days. – – Furious rabies-animal may act strange then wander off, attack and bite anything in its path, often frothing at the mouth Dumb rabies-no wandering, but paralysis of lower jaw followed by body paralysis and death Canine Brucellosis Bacterial disease spread through breeding Females – – – Abortion Failure to whelp Enlargement of lymph nodes Males – Swelling of scrotum and testicles Salmonellosis Bacterial disease spread by ingestion of food contaminated by feces. Basic Noninfectious Diseases of Dogs Heart Disease 2 types – – Congenital (birth) Contracted Symptoms – – – – Coughing at night during sleep Coughing during exercise Inability to exercise Open mouth breathing at rest Cataracts Cause cloudy, white opacity of the lens. Can be hereditary or not Can cause blindness More often affects older dogs Arthritis Degenerative joint disease that causes pain, lameness, and stiffness in the joints. Large, old and obese dogs are more prone to the disease. Basic Fungus Diseases of Dogs Ringworm Most common fungal disease. Symptoms: – – – Broken hairs around the face, ears or feet. Reddened skin and scaly skin develop. Crusting and scaling in severe cases. Blastomycosis Inhaling infected spores of soil enriched with bird or bat droppings. Symptoms: – – – – Coughing Rapid breathing Pneumonia Fever Internal Parasites of Dogs Ascarids or Roundworms May grow to 8 inches in length when mature Affect mainly puppies and deprive them of nutrients Transmitted by female dogs to puppies Severe infestation causes pot-bellied appearance Danger to children Hookworms Blood-sucking parasites that attach to the small intestine, causing small spots of bleeding Adult worms attach to the small intestine where they digest a plug of tissue. Heavy infestations cause the animal to appear weak, listless, and anemic Affects older dogs and puppies Whipworms Broad at one end and narrow at the other. Use the narrow end to attach to the cecum and lower digestive tract. Adults produce “shell” protected eggs that may live for years in the soil. Produce watery feces and may result in dehydration and death. Tapeworms Flat and segmented worms that live in the small intestine. Shed terminal segments in feces. Tapeworms Usually the largest worms affecting dogs reaching 1 foot or more in length Most depend on a host such as a flea or wild rabbit to develop. Not harmful for dogs, but may cause serious injury to humans. Heartworms Thin worms that live in the major artery carrying blood from the heart to the lungs. Serious threat to dogs causing major injury to vital organs. Transmitted by mosquitoes. Prevention is preferred to treatment which is only effective in early infestation. Heartworms Symptoms – – – Frequent coughing Labored breathing Fainting in severe cases Infectious Diseases of Cats Feline Panleukopenia Cat distemper caused by parvovirus or DNA virus. Affects cats younger than 16 weeks and has a 75% death rate. Spread by direct contact, infected food and water dishes, bedding, and litter boxes. Feline Panleukopenia Symptoms: – – – – – – – Depression Loss of appetite High fever Lethargy Vomiting Diarrhea Dehydration Feline herpesvirus (FHV) Respiratory infection caused by a DNA virus. Shed in discharges from nose, eyes and throat and transmitted by direct contact. Cats can become carriers, but vaccines are available. Feline Herpesvirus (FHV) Symptoms: – – – – – Depression Sneezing and coughing Severe eye and nasal discharges Increase in temperature Mouth ulcers Feline Enteric Coronavirus Caused by ingestion of contaminated feces in kittens between 4 and 12 weeks of age. Spread by ingestion of contaminated feces. Symptoms: – – – – – Low grade fever Vomiting Soft or watery diarrhea Blood in the feces Dehydration Feline Infectious Peritonitis (FIP) Disease caused by coronavirus that leads to organ failure. Coronavirus infections are more common, but few show signs. Symptoms – – – – Fever Refusal to eat Depression Weight loss Noninfectious Diseases of Cats Feline Urologic Syndrome (FUS) A.K.A. Feline Lower Urinary Tract Disease May range from mild inflammation to blockage of the urethra, uremic poisoning, and death. Causes of FUS Improper diet (where cats are fed high levels of magnesium and phosphorus) Low water intake that causes concentrations of various salts in the urine Possibly a virus Wet Eye Excessive tear production or blockage of drainage canals that drain tears to the nasal cavity causing tears to overflow at the corner of the eyes. Internal Parasites of Cats Toxoplasmosis Disease caused by infection with singlecelled protozoan parasite Toxoplasm gondii. Contracted from eating raw meat or contaminated feces. Fever, jaundice, and difficulty moving may result. No vaccination and humans can become infected through cat litter boxes. Ascarids (Toxocara cati) Ascarids from ingesting eggs passed in the feces of an infected animal or in the case of kittens from the milk of an infected mother cat. Severe cases may cause pot-bellied appearance (distended abdomen) and an unthrifty cat. Hookworm (Ancylostoma tubaeforme) Infection occurs when larvae is ingested from contaminated food or water, or when larvae penetrates the skin. May cause dark-colored feces and anemia from the loss of blood. Tapeworm (Dipylidium caninum) Require a cost other than the cat for development. Dipylidium caninum must be hosted by fleas and Tania taeniaeformis may be hosted by rats and mice. Neither type causes major harm. External Parasites of Small Animals Fleas Brown, blood-sucking insects of small size that move rapidly over the skin. May develop from eggs to adult in as little as 16 days. May first be detected in the groin and rump area of the animal. Fleas Cause irritation and extreme itching May be controlled with powders, dips, shampoos, collars, oral insecticides, foggers and sprays. Ticks Blood-sucking arthropods of the skin. Two main families of ticks: hard and soft Two types of hard ticks are a concern for dogs: brown dogs tick (can survive indoors) and American dog tick (lives on grass and shrubs) Ticks Main soft tick is the Spirose Ear Tick. Larvae and nymph stage live in and cause irritation to the outer ear canal. Lice Wingless insects that may bite or suck blood from the host. Not common on dogs. If infestation occurs, the dog will experience hair loss from scratching and rubbing. Two treatments 12 days apart with dips, dusts, or spray can control. Mites Tiny, eight-legged arachnids. Five species cause the most problems – – – – Demodectic mites Two types of sarcoptic mites Ear mites Cheyletiella mites Demodectic Mites No not usually cause problems. A severe infestation may result in hair loss, reddening of the skin, and encrusting in spots or over the entire body of the dog. Sarcoptic Mites Burrow within the outer layer of the skin. Highly contagious. Cause mange or scabies which case intense irritation and itching that may result in the dog injuring itself as it tries to scratch, chew or rub the skin. Ear Mites Highly contagious Found in the outer ear canal and other areas of dogs, cats, and rabbits. Common problem Infected animals may shake their heads. Flea products are effective treatment, as well as, ear drops. Cheyletiella Mites Contagious Cause a condition known as “walking dandruff” Severe scaling on the back may occur, but itching is not as severe as with other mite infestations. Chiggers Orange-red larvae stages of Trombicula mites that cause an itchy, red rash on the belly, face, feet and legs. – – Picked up from underbrush. Remain on the skin for a short time and usually do not require treatment other than something to stop the itching. Poisons Affecting Small Animals Insecticides May cause poisoning if ingested in sufficient amounts. Organophosphates and carbamate compounds are the main source of insecticidal poisoning. Boric acid from roach bait and arsenic from ant traps can also poison animals. Plants Philodendron, dieffenbachia, pothos, and caladium contain insoluble calcium oxadate crystals that cause irritation to the mouth and intestinal tract. Poinsettia, Japanese yew, azalea, and flower bulbs may cause mild intestinal upset. Plants Household Chemicals Ammonia, bleach, borates, hydroxides, pine oil, and phenol can cause sickness if pets ingest them. Rodenticides Strychnine and warfarin can cause internal bleeding and death if ingested in sufficient amounts. Herbicides Glyphosphate herbicides and arsenic-based weed killers can poison pets. Antifreeze Common source of poisoning because it has a sugary taste that animals like. Animal may appear drunk or depressed. Rabbit Diseases Enteritis Intestinal tract inflammation Probably the most common cause of death in rabbits Causes include: stress, unsanitary conditions, and high energy feeds Enteritis Symptoms Diarrhea stained with blood Animals will stop eating but drink lots of water Animals grind their teeth Almost 100% mortality rate Enteritis Treatment Prevention is best. Accomplished through proper environment, sanitary conditions, feeding rations that are high in fiber, low in energy, control of birds and rodents that carry the disease. Treatment when applicable is through broad spectrum antibiotics. Snuffles Disease aggravated by stressful conditions such as poor sanitation, poor ventilation, changing temperatures, shipping, or show conditions. Symptoms: persistent sneezing with a white colored nasal discharge. Prevention: Reduce stress through proper environment. Mastitis Inflammation of mammary tissue Also called caked breast May cause nursing problems Nursing baby rabbits may bite the nipples when they are unable to nurse Nursing mothers may refuse to nurse the young. Mastitis Prevention and Treatment Remove concentrates from the diet for 72 hours. Widespread cases, clean and disinfect all nesting boxes. Wry Neck Condition caused by inflammation of the inner neck. Head tilted to the side is the most common symptom. Often found where snuffles are also present. Best prevented by controlling upper respiratory diseases. Fur Chewing Pulling of fur from itself or other rabbits caused by simple boredom, a nutrient deficiency, and a low-fiber diet. Prevention and treatment: Best by feeding hay or straw to add fiber to the diet. Adding magnesium oxide to the ration also helps. Hutch Burn Chapped or burning condition of the external genital area of the doe. Caused by sitting in dirty, wet, urine soaked bedding. Prevention and treatment: keep bedding clean. Treatment is with antibiotic creams. Sore Hocks Ulcerated area on the bottom of the foot pads most often associated with rough wire cage floors and size of the foot pad not supporting the weight of the animal. Large breed with long foot pads are most often affected. Sore Hocks Prevention and Treatment Get off wire and place on a solid surface Apply astringents to the sore pads – – – Petroleum jelly Bag balm (for cow udders) Human hemorrhoid ointments Hamster Diseases Wet Tail (Enteritis) Most common disease of hamsters Caused by poor sanitation, bacteria, viruses, and diet. Wet Tail Symptoms Wetness around the tail and rear of the animal caused by runny diarrhea. High death rate occurs within 2 days of symptoms appearing. Most often associated with poor sanitation caused by general neglect and poor care. Wet Tail Prevention and Treatment Change and disinfect spoiled bedding, cages, and equipment and isolate infected animals. Keep temperature around 70 degrees to avoid estivation (sleep above 80 degrees) or hibernation (below 50 degrees). Avoid drafts. Animals do not respond well to treatment. Common Diarrhea Caused by incorrect diet with overabundance of green leafy materials, vegetables, or fruits. Should not be confused with serious infections. Correct by removing green leafy vegetables and fruits and feeding dry grains and seeds. Gerbil Diseases Colds Gerbils are hardy and seldom affected by disease, but colds are most common. Symptoms: – – – Loss of appetite Constant sneezing Runny eyes and nose Cold Prevention and Treatment Reduce stress caused by overcrowding (gerbils need more space than hamsters) Avoid drafts, humidity and temperature fluctuations. Red Nose Commonly caused by the Staphylococcus bacteria. Animal will recover without any medication. Symptoms: – – Hair loss Red, swollen areas of the skin around the nose and muzzle Rat Diseases Respiratory Disease Common disease caused by Microplasma pulmonis Symptoms: – – – – – – Nasal discharge Snuffling Rattled breathing Rubbing eyes and nose Tilted head Uncoordinated and circling Mouse Diseases Mouse Diseases Hardy animals with proper diet, housing, and exercise. Respiratory disease can be caused by several organisms and result from changes in temperature, drafts, high humidity. Symptoms: squeaking or rattling breath, runny nose, watery eyes and fur loss. Mouse Diseases Salmonella and related bacteria are responsible for many of the serious infectious diseases. Control with clean cages, clean water, clean feed, and parasite control. Guinea Pig Diseases Guinea Pigs Very healthy under favorable conditions. Avoid drafts and keep temperature and humidity constant to avoid problems. Common cold and respiratory diseases can be a problem if environment is not good. Colds in Guinea Pigs Animals become lethargic, listless, have nasal discharge and sneezing Prevention: – – – Maintaining a good environment Immediate treatment with broad-spectrum antibiotics Increase Vitamin C Toxemia Build-up of toxins in the blood that developed in late pregnancy. Symptoms: females will be lethargic, go off feed, refuse to eat, and have difficulty breathing. Prevention and Treatment: Feed a high quality diet to the pregnant female and add ½ teaspoon of sugar in the water bottle. Chinchilla Illnesses Chinchilla Environment Need proper nutrition and a clean, dry, draftfree environment with low stress. Provide adequate ventilation Avoid temperatures above 80 degrees or cold drafts and high humidity Pseudomonas aeruginosa Organism that causes infection in wounds, inflammation of eyes and ears, pneumonia, intestinal inflammation, uterine inflammation, and poisoning of the circulatory system. Eye Inflammation (conjunctivitis) Swelling and redness around the eyes, sensitivity to light, watering, and pus formation. Treatment: Isolate infected animals, wash eyes gently with warm boric acid solution, and use ophthalmic medications. Clean cages and feed containers. Inner Ear Infection (otitis) Symptoms: Twisting and lowering of the head, hanging head to one side, running in a circle. Prevention and Treatment: Avoid drafty, cool environmental conditions. Clean the ear with warm boric acid solution and treat with ear drops. Pneumonia Symptoms: listlessness, failure to eat, breathing difficulty, swollen abdomen Prevention and treatment: Eliminate cold drafty, and high humidity conditions and treat immediately with aureomycin, penicillin, or other antibiotics. Impaction Lower digestive system becomes tightly packed with food material or feces. May then follow diarrhea. Caused by poor quality feed, stress, and poor nutrition. Animal is often humped with chin resting between its front feet. Treatment for Impaction Give a dropper full of mineral oil daily OR Add up to three full droppers of grapefruit juice to the animal’s diet. Ferret Illnesses Canine distemper A disease that also affects dogs and is highly contagious. Usually results in death. Symptoms: discharge from the eyes and nose, breathing problems, diarrhea. Canine Distemper Treatment Vaccination is important. Vaccinate at 12 weeks of age and give boosters annually to prevent canine and feline distemper. Treatment is not effective. Hemorrhagic enteritis Bloody diarrhea is commonly seen Symptoms: Go off feed, bloody diarrhea, weight loss, dehydration, possibly death Prevention and treatment: Treat with antibiotics and sulfur material. Botulism Caused by toxin produced by bacteria. Symptoms: breathing difficulty and paralysis Death can occur without symptoms. Keep food supply fresh. Disease Prevention and Treatment for Pocket Pets Maintain Good Sanitation Remove spoiled urine soaked bedding regularly Remove urine and feces contaminated feed regularly Keep fresh water available at all times Provide a Good Environment Keep animals free of drafts and eliminate any cool, damp drafts immediately Maintain low humidity. Higher humidity contributes to respiratory diseases. Maintain constant temperature that does not fluctuate to a great degree. Provide adequate ventilation to remove stale air. Feed an appropriate ration. General Disease Treatment for Pocket Pets First, isolate sick animals to prevent the spread of disease. Remove and replace bedding from the cage of a sick animal. Chemically disinfect and sanitize cage prior to installing new bedding. Use medicated water routinely when disease is a constant threat. General Disease Treatment for Pocket Pets Use proper treatments and antibiotics if recommended. Dispose of dead animals properly (burn and bury in some cases) Cull animals that do not show signs of improvement. Improve environmental conditions that may be causing disease. General Disease Treatment for Pocket Pets Avoid breeding animals that may have inherited diseases. Use recommended pesticides to control pests. Parasites of Birds Internal Parasites Rarely a problem with birds Roundworms – – – – Diagnosis is by observing feces for long, thin, white worms. Contracted from ingesting worm eggs in contaminated feces, soil, or food. Symptoms: blockage of intestines, poor plummage, weight loss, diarrhea. Treatments are available Internal Parasites Tapeworms – – – – Diagnosed by observing small rice-like segments in the feces Contracted from eating an intermediate host such as house flies, fleas, ticks, or earthworms. Proper cleaning and sanitation are the best prevention. Treatment with piprazine, nicotine sulfate and Kamal powder External Parasites Red Mites – – – – Appear as tiny red specks and feed on blood of infected birds at night, causing restlessness, scratching, and picking at their feathers. Spread through contact with infected birds. Adults may be dusted with pyrethium powder. Clean and disinfect all cages and nest boxes. External Parasites Feather Mites – – – – – Cause a bird to chew or pick its feathers. Look for small, gray-colored moving specks Feed on the bird during both day and night Symptoms: restlessness, severe scratching, feather picking, skin irritation Cages and equipment should be treated with nicotine sulfate, Malathion, or coumaphos and birds should be sprayed with a mite spray. External Parasites Scaly Leg Mites – – – – Tunnel under the scales on the legs of budgerigars, lovebirds, and canaries. Live their entire life cycle on the bird. Symptoms: white scaly deposits that become thickened, enlarged, and encrusted Treatment: Use Vaseline or mineral oil to kill the mites and loosen deposits. This also suffocates the mites. Scaly Leg Mite Bacterial Diseases in Birds Parrot Fever Chlamydiosis or psittacosis Bacterial disease that affects the liver and spleen. Contracted mainly through feces and contaminated food and water. Symptoms: nasal discharges, listlessness, appetite loss, weight loss, greenish-colored diarrhea and labored breathing. Parrot Fever Psittacosis can be transmitted to humans. Treat birds with chlortetracyclineimpregnated seed for at least 21 days. Bumblefoot A painful ailment associated with staphylococcal infections. Symptoms: feet and joints become hot and swollen with a thick, grayish white fluid and not walking or clasping onto perch. Prevent by using suitable perches and sanitation. Treatment is with antibiotics. Bumblefoot Viral Diseases in Birds Psittacine Beak and Feather Disease A.K.A. French Molt Viral disease that attacks the immune system. Symptoms become evident at the first molt when new feathers do not emerge or are deformed and break off. Nails may be soft, overgrown, and lose their pigment. Psittacine Beak and Feather Disease There is no cure for this disease. Treatment is with vitamins, minerals, and control of secondary diseases through sanitation. Newcastle Disease Viral disease that has high mortality rates and spreads rapidly. Imported birds are the main source of possible infection. Symptoms: Respiratory difficulty (wheezing) followed by tremors, wing droop, and a twisted neck. Birds should be vaccinated to prevent the disease. Nutritional Problems in Birds Goiter Swelling of the thyroid glands in the neck and interference with breathing. Major cause is iodine deficiency. Especially a problem for budgerigars Rickets (Osteomalacia) Imbalance or deficient amount of calcium, phosphorus, or Vitamin D3 that causes deterioration or softening of the bones. Symptoms: lameness, stiff-legged gait, constant resting in the squatting position, decreased growth. Oyster shell or coarse limestone in the diet and Vitamin D3 supplementation is the best preventative. Obesity Too much food, not enough activity or seeds high in fat. Bird owners should avoid feeding too many sunflower seeds if obesity is a problem. Other Aviary Problems Overgrown Claws Can result in injury if they become entangled in the cage. May be clipped with pet nail clippers. Avoid the pinkish streak in the center of the claw. It is a blood vessel. Feather Plucking Boredom, bad diet, needs mate, lack of bathing Birds living indoors need regular bathing or spraying to encourage preening. Preening is the process that birds go through in cleaning and trimming its feathers with its beak. Symptoms of Problems with Birds Sleeping on two legs may indicate that a bird is uncomfortable or ailing. Birds normally sleep on only one leg. A bird that fluffs its feathers out is usually chilled and trying to retain body heat. If feces are runny, a digestive ailment may be the problem. Not flying and lack of activity may indicate the bird is sick. Symptoms of Problems with Birds Eye discharges or continually closed eyes are an indication of cold, etc. Wheezing, noisy, or irregular breathing may be a sign of a respiratory problem. Not eating or very little eating indicates a loss of appetite that is often associated with sickness. Prevention of Diseases and Ailments Select a healthy bird Place bird in a dry, warm, draft-free place Subject the bird to little stress No other animals should be around Quarantine and observation period of at least 3-4 weeks before introducing to other birds. Keep perches and cage clean Prevention of Diseases and Ailments Sanitation is extremely important—should provide fresh food and water. Prevention of Diseases and Ailments Bathing and spraying reduces feather dust and dirt and cuts down on mites – – Small birds prefer to bathe in a container which may be placed in the cage at regular intervals for 30 minute time periods. Large birds need to be sprayed with a fine mist from a plant sprayer. Mist should be sprayed above the animal and allowed to filter down. Do not saturate, but gently spray 2-3 times per week. At the First Sign of Illness Cage temperature should be maintained between 85-90 degrees F. – – – Move the cage to a warmer location Adjust the temperature with a light bulb near the cage or a heating pad under the cage. Provide 2 or 3 perches so that the bird can find the most comfortable temperature At the First Sign of Illness Partially cover the cage to prevent drafts Provide quick energy fluids such as sugar water, honey water, or orange juice. Diseases of the Aquarium Signs and Symptoms of Disease Fish are behaving unusual/strange Fish are floating to the surface, sinking to the bottom, or leaning to the side of the aquarium. Fins are unusually lying flat against the body. Rolled or caudal fins A fish is off by itself and not swimming with the school. Signs and Symptoms of Disease Fish appears to be in slow motion and not keeping up with the other fish. Breathing seems unusually faster and deeper than normal. Fish is at the surface gasping for air. Rubbing/scratching against objects in the aquarium. Not interested in eating. Signs and Symptoms of Disease Belly appears caved in or unusually thin. Belly appears bloated or swollen. Color of fish has changed or unusual. Fin appears frayed. Back and spinal column appear distorted. Eyes are not clear, appear cloudy. White spots are covering the body. Signs and Symptoms of Disease Scales that stick out from the body instead of lying flat. Protruding eyes Anal discharge hanging from the fish. Parasites of Fish White Spot (Ich) Caused by the parasitic organism Ichthyophthirius multifiliis and causes numerous white spots on the body and fins of a stressed fish. One of the most common diseases in aquarium fish. Slime Disease Parasites attack skin of fish causing a large amount of mucus. May cause death if it attacks the gills. Hole-In-The-Head Organism Hexsamita live under skin in muscle tissue and make the tissue break down and skin opens up to make the fish appear to have holes. Velvet Disease Organism Oodinium penetrates skin cells and feed on fish. White Fungus Growth White growth around mouth, fins, eye, and gills. A secondary infection is usually present already. Flukes Worm-like parasite that attaches to the gills and body of the fish. Anchor Worms Adhere and burrow under scales to attack the muscles Fish Lice Attach to body of fish and pierce skin to discharge a poison. Bacterial Diseases Affecting Fish Fin Rot Where the edges of the fish’s fins start to appear frayed and ragged, lose their color and the tissue between the fins breaks down. Mouth Fungus Caused by bacteria with a white tufty material appearing around the mouth and white patches on the skin. Neon Disease Caused by parasite Pleistophora hyphessobryconis. This organism is found in the fish’s body tissue where it causes the production of spores which are released when it dies. Tuberculosis Causes by bacteria that invades the organs and tissues of the body. Pseudomonas and Aeromonas Secondary infections in fish that are already sick. Fish have swollen bellies, lesions or ulcers. Environmental Problems (In the Tank) Environmental Problems Lack of oxygen and overabundance or carbon dioxide can be readily observed when almost all of the fish are swimming near the surface gulping for air. Incorrect water pH-causes respiratory problems and excess mucus production. Environmental Problems Chemical filtration ability reduced and ammonia builds up—observed by cloudy, murky water Gravel filtration system pollution buildup of iron sulphite can be observed by the black color on the gravel. Treatment Use of chemicals in the water with the aquarium being thoroughly cleaned before the fish are returned. Placement of fish in a hospital tank for treatment before returning to normal tank. Most treatments can be found at the local pet store. Amphibians and Reptiles Salmonella Bacterial disease that can be transmitted to humans. Affects the digestive tract and causes watery, green foul-smelling diarrhea. Mouth Rot Fungal disease associated with sores or open wounds in the mouth. Mites and Ticks External parasites that attack amphibians and reptiles. Mites usually go undetected until there is a heavy infestation. Symptoms: anemia, anorexia, depression, stress, listlessness, lack of appetite, possible death.