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LS.2.d The student will investigate and understand that all living things are composed of cells. Key
concepts include cell division.
Link
Time: 2 minutes
Begin class by Kaitlin handing out a set of flashcards to each pair (Have Alyssa work in a group of 3 or if someone is absent work with
them). The flashcards should have interphase, prophase, metaphase, anaphase, telophase, and cytokinesis written on them. Carly
explain that pairs must order these cards in the order that they appear in cell division. Give students exactly one minute to do this,
and while they work, Carly and Kaitlin set up poster board/Active learning activity. Students share their orders, and as they do that,
Carly walk around with the notes worksheet to fill out.
Kaitlin introduce topic and tell students to check their answers as we go through the notes.
Engage and Educate
Time: 3 minutes
Kaitlin ask students the difference between mitosis and meiosis- students should answer one is for sex the other is for identical.
Maybe mention growth, repair, and replacing other cells- Once at least one student answers, give long definition to
 Mitosis- mitosis is to produce new cells for growth and repair that are identical to the parent cell.
 Meiosis- produce reproductive (sex) cells that carry half the genetic material of the parent.
Ask why cells have to undergo mitosis and list factors-replace, repair, and grow - first part should take about a minute.
Begin talking about the different stages beginning with:
Interphase-The cell is engaged in metabolic activity and performing its duty as part of a tissue. The DNA duplicates during interphase
to prepare for mitosis. Chromosomes are not clearly discerned in the nucleus, although a dark spot called the nucleolus may be
visible (Growth divided into 2 parts- G1 and G2- G2 preparing for division)
Prophase-Chromatin in the nucleus begins to condense and becomes visible in the light microscope as chromosomes. The nuclear
membrane dissolves and the chromosomes begin moving into place. (the nuclear membrane disappears and the DNA in the cell
starts getting ready to divide)
Metaphase- Spindle fibers align the chromosomes along the middle of the cell nucleus.. This organization helps to ensure that in the
next phase, when the chromosomes are separated, each new nucleus will receive one copy of each chromosome. (chromosomes line
up)
Anaphase-The paired chromosomes separate, and move to opposite sides of the cell.
Telophase-New membranes form around the daughter nuclei while the chromosomes disperse and are no longer visible under the
light microscope (basically done, but not separate cells yet)
Cytokinesis-the partitioning of the cell may begin during telophase (the cell pinches in half and becomes 2 daughter cells)
Active Learning
Flat clay balls with “chromosomes”
in it under a smaller flat ball.
Students should:
1. Pull off the membrane of
the nucleolus
2. Line up the chromosomes
3. Tie string around
chromosome middles
4. And attach at the
centrioles on either end of
the cell
5. Pull the cell apart
6. Round out and create a
new nucleolus
Worksheet with the directions on it
given to students. The sheet will
have a few extra definitions on it to
explain parts of the cell when it
undergoes mitosis that are different
from normal.
Time: 4 minutes
Kaitlin: we are now going to do an
activity where you will divide a cell.
In these bags you have everything
that you will need.
Carly: as you can see, our cells are
made of clay and we are going to
separate them together using the
steps that we just learned
Kaitlin: Please follow the
instructions on your piece of paper
so that the cell divides properly!
Carly: if you don’t know what a part
is, look at the definitions please
Kaitlin: we will give you a couple of
minutes to do this and then we will
quickly discuss a few of the
questions on the bottom of the
sheet.
Multiple intelligences:




Interpersonal- talking with
partners to work out the
cell split
Spatial- understanding how
the cell woks when it splits
Bodily Kinesthetic- getting
up and moving
Linguistic- talking and
understanding definitions
Learning styles:



Kinesthetic- students
actively break apart their
cells
Visual- the worksheet and
diagrams
Auditory- discussion with
partners
Accommodations: do as a class if
pressed for time
Reflect
Time: 1 minute
Turn and talk- students discuss and write down two of the four questions on the last part of the worksheet. Students
should go into as much depth as possible in the time that they have.
Now and Then
As students continue, understanding the stages of mitosis will help them to figure out that place in the larger scheme of
life.
Name_______________________
Date________________________
Section______________________
Cell Division
What is Mitosis?
What is Meiosis?
Why do cells divide?



Life Cycle of the Cell
Stage
Definition
The cell is engaged in metabolic
activity and performing its duty as
part of a tissue. The DNA duplicates
during interphase to prepare for
mitosis.
Chromatin in the nucleus begins to
condense and the nuclear membrane
dissolves and the chromosomes begin
moving into place.
The chromosomes align along the
middle of the cell nucleus. This
ensures that each new nucleus will
receive one copy of each chromosome
The paired chromosomes separate,
and move to opposite sides of the cell
New membranes form around the
daughter nuclei while the
chromosomes disperse
the partitioning of the cell may begin
during telophase
Diagram
Name_______________________
Date________________________
Section______________________
Cell Division
Make Your Own Cell Divide
Please do ALL of this page with your partner. The room should not be quiet
while you are working!
Extra Vocab:
Word
Definition
Nucleolus
Chromosomes
Spindle fibers
Centrioles
Directions:
1.
2.
3.
4.
5.
6.
7.
8.
9.
Take out your clay cell from the bag
Locate the nucleolus of the cell
Pull off the membrane of the nucleolus
Line up the chromosomes in the correct direction to be pulled apart
Slip the string around chromosome middles
Locate the centrioles
Attach the other end of the string to the centrioles on either end of the cell
Pull the cell apart
Round out the cell and create a new nucleolus
Questions:
What does the pulling off of the nucleus symbolize in this process?
_____________________________________________________________________________________
What part of cell division do the strings represent?
_____________________________________________________________________________________
Why do you think the chromosomes line up in the middle?
_____________________________________________________________________________________
How was this similar/different from real cell division?
_____________________________________________________________________________________
_____________________________________________________________________________________
_____________________________________________________________________________________
_____________________________________________________________________________________
Name_______________________
Date________________________
Section______________________
Cell Division
What is Mitosis?
A process that produces new cells that are identical to the parent
What is Meiosis?
A process that produces sex cells that have half of the genetic information of the parent
Why do cells divide?

Grow

Repair

Reproduce
Life Cycle of the Cell
Stage
Definition
Interphase
The cell is engaged in metabolic
activity and performing its duty as
part of a tissue. The DNA duplicates
during interphase to prepare for
mitosis.
Prophase
Chromatin in the nucleus begins to
condense and the nuclear membrane
dissolves and the chromosomes begin
moving into place.
Metaphase
The chromosomes align along the
middle of the cell nucleus. This
ensures that each new nucleus will
receive one copy of each chromosome
Anaphase
Telophase
Cytokinesis
The paired chromosomes separate,
and move to opposite sides of the cell
New membranes form around the
daughter nuclei while the
chromosomes disperse
the partitioning of the cell may begin
during telophase
Diagram
Name_______________________
Date________________________
Section______________________
Cell Division
Make Your Own Cell Divide
Please do ALL of this page with your partner. The room should not be quiet
while you are working!
Extra Vocab:
Word
Nucleolus
Chromosomes
Spindle fibers
Centrioles
Definition
Small, dense spherical structure in the cell that
holds the chromosomes.
A threadlike structure of nucleic acids and
protein found in the nucleus that carries the
genetic information of the cell
A protein structure that divides the genetic
material in a cell during the division process
An organelle near the nucleus, occurring in
pairs to produce spindle fibers for cell division
Directions:
10. Take out your clay cell from the bag
11. Locate the nucleolus of the cell
12. Pull off the membrane of the nucleolus
13. Line up the chromosomes in the correct direction to be pulled apart
14. Slip the string around chromosome middles
15. Locate the centrioles
16. Attach the other end of the string to the centrioles on either end of the cell
17. Pull the cell apart
18. Round out the cell and create a new nucleolus
Questions:
What does the pulling off of the nucleus symbolize in this process?
Dissolving the nuclear membrane__________________________________________________________
What part of cell division do the strings represent?
The Spindle Fibers______________________________________________________________________
Why do you think the chromosomes line up in the middle?
So that the nucleus of each new cell will receive all of the information that it needs__________________
How was this similar/different from real cell division?
Open ended, but answers can relate to the size, material, color, mechanics of using the clay cells to
represent cell division___________________________________________________________________
_____________________________________________________________________________________
_____________________________________________________________________________________
_______________________________________________________________