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A. Example of a patient without left ventricle (LV) dyssynchrony on gated myocardial perfusion single-photon emission computed tomography (SPECT). Synchronous contraction pattern is reflected by homogeneous phase angle distribution of polar map (left) and narrow highly peaked histogram (right). At the 6-month follow-up, no improvement in New York Heart Association (NYHA) functional class was observed, and LV ejection fraction remained unchanged (32% at baseline vs 33% at 6-month follow-up). B. Example of a patient with extensive LV dyssynchrony on gated myocardial perfusion SPECT. LV dyssynchrony is indicated by heterogeneous phase-angle distribution of polar map (left) and wide histogram (right). At the 6-month follow-up, NYHA functional class improved from 3 to 2, with increase in LV ejection fraction from 21% to 33%. CRT, cardiac resynchronization therapy. Reproduced Source: NUCLEAR CARDIOLOGY, Hurst's The Heart, 14e with permission from Boogers MM, Van Kriekinge SD, Henneman MM, et al: Quantitative gated SPECT-derived phase analysis on gated myocardial Citation: Fuster V,ventricular Harrington dyssynchrony RA, Narula J, Eapen ZJ. Hurst's The Heart, 14e; 2017 Available at: http://mhmedical.com/ May 07, perfusion SPECT detects left and predicts response to cardiac resynchronization therapy, J Nucl Med. Accessed: 2009 May;50(5):7182017 353 725. Copyright © 2017 McGraw-Hill Education. All rights reserved