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Integrated Disease Surveillance and Response (IDS/R) in the African Region Mary Harvey and Patrick Swai SOTA June 12, 2002 AFRO GOAL Improve the well-being of the 600 million people living in the 46 Member States of the WHO Regional Office for Africa through implementation of integrated disease surveillance for infectious diseases and improved preparedness for epidemic response WHO/AFRO Priority Infectious Diseases • Diseases targeted for eradication/elimination • Epidemic Prone Diseases • Diseases of Public Health Importance General Objective of IDS To provide evidence on which to base decisions and public health interventions for the control of communicable diseases Specific Objectives of IDS 1. To strengthen the capacity of health workers to conduct surveillance activities. 2.To Integrate multiple surveillance systems for efficiency of staff, forms, resources. 3. Improve use of Information for decision making. 4. To improve the flow of surveillance information between and within levels of the health system 5. To strengthen laboratory capacity and involvement in confirmation 6. To increase involvement of clinicians Steps for IDS Strategy implementation Major achievements • Completion of IDSR TG, tools / instruments • Strengthening of the Laboratory • Training • Indicators drafted and being field tested • Support from MOH, USAID, UNF ,CDC, WHO • National IDS coordinating committees • Progress observed on implementation of IDSR in Member States Status of IDS Implementation Non AFRO country Not started Initial contact made Preparing assessment Assessment completed Plan of action completed Guidelines adaptation initiated Guidelines adapted Challenges • Ownership and sustainability • Availability of resources • Commitment of stakeholders • Involvement of all levels Expected Outcomes of IDS • Simplification of recording and reporting • Information is more accessible and timely • Action taken is more timely and appropriate • Resources are used more effectively Developing experience and evidence in surveillance implementation in Tanzania Dr. Patrick Swai USAID/Tanzania Milestones of IDS in Tanzania • 1998 National level assessment • 1998 Adoption of IDS strategy • 1999 Implementation plan developed • 2000 IDS Task Force created • 2001 National IDS guidelines for 13 priority diseases • 2001 Lab networking guidelines • 2002 Development of draft District analysis book Source of USAID funds for IDS implementation in Tanzania • Africa Bureau – Providing support to WHO, (including the 1998 assessment) • Tanzania Mission – operationalizing the IDS strategy and strengthening surveillance implementation • Bureau of Global Health – developing evidence of successful programming USAID-funded partners in local IDS implementation in Tanzania • National Institute for Medical Research (NIMR) • Partners for Health Reform plus (PHRplus) • Centers for Disease Control and Prevention -- NCID and EPO/DIH • CHANGE Project • HealthTech Structure of the Tanzania Health System and Relevance for IDS Communities Facilities District Reg’l Nat’l Know what to report when to health care system for action; Participate in response and prevention Identify cases, report, respond and participate in public health actions Hub of decision making, response/ action and resource mobilisation Support for lab, outbreak investigation, training Policy, direction, plan, country guidelines WHO Strategy, guidelines, tools How the implementation team contributes to IDS strengthening • WHO/AFRO – support to creating strategy, guidelines, and tools – IDSR guidelines provide a comprehensive technical definition of a functioning system. – Local implementation process is beyond the scope of regional guidelines Questions for country level implementation: • What obstacles do districts, facilities, and communities face in operationalizing the system? • What are the best strategies for overcoming these obstacles? What are some of the obstacles that districts in Tanzania face? • Very limited diagnostic confirmation capacity • Lack of adequate communications between levels • Barriers to adequate transport of specimens • Low motivation and capacity for analysis (and use) of information for public health action • Poor coordination of operationalizing available Need a guiding “road map” for IDSR resources How we are breaking ground in implementation in Tanzania • Support the development of new ID surveillance and public health action technologies and tools for both epidemic and non-epidemic diseases • Conduct research into critical issues surrounding ID surveillance and response that will support its successful adoption by other countries How we are breaking ground in implementation in Tanzania • Disseminate lessons learned • Develop successful examples of ID surveillance and response that can be adopted by other districts in Tanzania and other countries to address the real obstacles at local levels Implications for other countries for implementing IDSR • Provide a model for other countries • Answer questions with operations research • Development of best practices • Documentation and transfer of experiences and lessons learned • Dissemination of tools and materials for implementation Thank you! Milestones of IDS in Tanzania • • • • • 1998 National level assessment 1998 Adoption of IDS strategy 1999 Implementation plan developed 2000 IDS Task Force created 2001 National IDS guidelines for 13 priority diseases • 2001 Lab networking guidelines • 2002 Development of draft District analysis book • 2002 The coordinated implementation team initiated implementation in focus districts Source of USAID funds for IDS implementation in Tanzania • Africa Bureau – Providing support to WHO, (including the 1998 assessment) • Tanzania Mission – operationalizing the IDS strategy and strengthening surveillance implementation • Bureau of Global Health – developing evidence of successful programming around surveillance; dissemination of tools, materials, and lessons learned to other countries USAID-funded partners in local IDS implementation in Tanzania • National Institute for Medical Research (NIMR) • Partners for Health Reform plus (PHRplus) • Centers for Disease Control and Prevention -- NCID and EPO/DIH • CHANGE Project • HealthTech Structure of the Tanzania Health System and Relevance for IDS Communities Facilities District Reg’l Nat’l Know what to report when to health care system for action; Participate in response and prevention Identify cases, report, respond and participate in public health actions Hub of decision making, response/ action and resource mobilisation Support for lab, outbreak investigation, training Policy, direction, plan, country guidelines WHO Strategy, guidelines, tools How the implementation team contributes to IDS strengthening • WHO/AFRO – support to creating strategy, guidelines, and tools – IDSR guidelines provide a comprehensive technical definition of a functioning system. – Local implementation process is beyond the scope of regional guidelines • Local-level (country) implementation: operationalize the strategy and guidelines Questions for country level implementation: • What obstacles do districts, facilities, and communities face in operationalizing the system? • What are the best strategies for overcoming these obstacles? What are some of the obstacles that districts in Tanzania face? • Very limited diagnostic confirmation capacity • Lack of adequate communications between levels • Barriers to adequate transport of specimens • Low motivation and capacity for analysis (and use) of information for public health action • Poor coordination of available resources • Undefined roles and responsibilities for IDS Need a guidinglevel “roadstandards map” for operationalizing • National and policies IDSR missing How we are breaking ground in implementation in Tanzania • Support the development of new ID surveillance and public health action technologies and tools for both epidemic and non-epidemic diseases • Conduct research into critical issues surrounding ID surveillance and response that will support its successful adoption by other countries • Coordinate with global and national institutions to provide training to develop the necessary skills needed for ID surveillance and response How we are breaking ground in implementation in Tanzania • Disseminate lessons learned • Develop successful examples of ID surveillance and response that can be adopted by other districts in Tanzania and other countries to address the real obstacles at local levels Implications for other countries for implementing IDSR • Provide a model for other countries • Answer questions with operations research • Development of best practices • Documentation and transfer of experiences and lessons learned • Dissemination of tools and materials for implementation Epidemic Preparedness and Response • Yellow Fever epidemics in Cote d'Ivoire, Ghana, Guinea and Liberia in 2000-2001 • 5 Countries accounted for 75% of the 61,988 Meningitis cases and 67% of the 6,172 deaths:Burkina, Niger, Benin, Mali, Ethiopia, and Chad • Cholera in South Africa, Malawi, Madagascar, Zambia • Ebola: Gabon, RDC, Uganda Meningitis Epidemics in Africa • Meningitis epidemics historically caused by serogroup A meningococci • Other serogroups (B, C, W135) often associated with sporadic disease in Africa • However, W135 outbreak in Saudi Arabia in 2000 created alert (264 cases) Meningitis Epidemic Preparedness and Response • 1. Epidemic Management committee • 2. Laboratory-based surveillance and alert system • 3. Strengthen Laboratory • 4. Vaccination with A/C vaccine • 5. Case management • 6. Social mobilisation Definition of Alert and Epidemic Thresholds for Meningococcal Meningitis in Highly Endemic Countries in Africa [a] Alert threshold Epidemic threshold Population Over 30,000 Population Under 30,000 5 cases / 100,000 inhabitants / week 2 cases in the same week If (1) No epidemic for at least three years and vaccination coverage is under 80%, or (2) Alert threshold crossed early in the dry season [b] 10 cases / 100,000 inhabitants / week Other situations 15 cases / 100,000 inhabitants / week Or An increase in the number of cases in relation to previous non-epidemic years 5 cases in the same week Or Doubling of the number of cases in a three-week period[c] Or Other situations should be studied on a case-by-case basis [b, d] Meningitis Epidemic, Burkina Faso 2002 (Jan 1 to May 5, 2002) • 12,284 cases and 1,411 deaths identified • Overall case fatality ratio (CFR) 11.5% • Overall disease incidence rate: 99 cases/100,000 population • 33 health districts in (22 in epidemic, 12 in alert) at peak of the epidemic (week 14) Challenges Presented • W135 meningococci as the predominate cause • First W135 epidemic of this magnitude • W135-containing meningitis vaccine not currently available for large use in Africa (low quantity, high cost) Issues Regarding Serogroup W-135 Epidemiological questions • Causes for emergence of W-135 disease? –Changes in carriage –Changes in immunity –Other changes in host (risk factors) –Other changes in pathogen –Changes in environment –Implication of previous vaccination (A/C)campaigns Issues Regarding Serogroup W-135 Implications for Public Health Response in the Future • Maintain/improve meningitis laboratorybased surveillance 2002-2003 • W-135 containing polysaccharide vaccine for future epidemics –Monovalent (W135) Vs Quadrivalent (A/C/Y/W135) • Development and introduction of W-135containing conjugate vaccine • Case management • Economics • Lessons learnt Support Impacts Success IDS requires: • Commitment • Resources – human – budgetary • Transport • Communications • Training • Supervision • Laboratories