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Dr. Yonit Szwec-Levin Cell: 054-3557003 E-mail: [email protected] EDUCATION 2007 D.M.D Tufts University School of Dental Medicine, Boston 2005 - 2007 Faculty track DMD at Tufts University School of Dental Medicine, Boston 1999 Israeli board certified in Endodontics 1995 - 1998 Endodontic residency at the Hebrew University, Hadassah, School of Dental Medicine, Jerusalem, Israel 1991 D.M.D Hebrew University, Hadassah, School of Dental Medicine, Jerusalem, Israel 1985–1991 Hebrew University, Hadassah, School of Dental Medicine, Jerusalem, Israel CLINICAL PRACTICE 2011- Dental Clinics , Israel. Practice limited to Endodontics 2007 – 2011 Private practice in Massachusets. Practice limited to Endodontics 2001 – 2003 Tufts Dental Clinc, Lowell, MA 1995 – 2000 Dental Clinics , Israel. Practice limited to Endodontics 1991 – 1995 General Dentistry TEACHING EXPERIENCE 2003 – 2011 Assistant Professor, Department of Endodontics, Tufts University School of Dental Medicine, Boston. 2002 Assistant Clinical Professor, Department of Endodontics, Tufts University School of Dental Medicine, Boston, Mass. 2001 Instructor, Department of Endodontics, Tufts University School of Dental Medicine, Boston, Mass. Abstracts presented in conferences: 1. Alt-Holland, A., Szwec-Levin, Y., DesRochers, T.M., Shamis, Y. Green, D., and Garlick J.A.: Abrogation of E-cadherin and loss of cell-cell adhesion directs the transition to individual carcinoma cell invasion through activation of FAK and Src kinases. 4th IABMR Annual Symposium, Boston, Massachusetts, USA, December, 2007. (Achieved 2nd place in the IABMR Award Competition - In Recognition of Excellent Scientific Study Presentation) 2. Jordan, S., Alt-Holland, A., Sowalsky, A., Szwec-Levin, Y., Feig, L., and Garlick, J.A. A role for RalB in E-cadherin-deficient cells during squamous cell carcinoma progression. Bates-Andrew Research Day, Tufts School of Dental Medicine, March, 2008. (Achieved 2nd place Award for Predoctoral Table Clinic) 3. Jordan, S., Alt-Holland, A., Sowalsky, A., Szwec-Levin, Y., Feig, L., and Garlick, J.A. Loss of RalB in adhesion-deficient tumor cells promotes hyperproliferation. IADR, The Metro Toronto Convention Centre, Toronto, Canada, July, 2008 (Selected for Oral Presentation) 4. Alt-Holland, A., Szwec-Levin, Y., Sowalsky, A., Feig, L. and Garlick, J.A. Reverting the aggressive behavior of squamous cell carcinoma: Silencing of FAK and Src kinases normalize human, 3D bioengineered tissues comprised of E-Cadherin-deficient tumor cells. 5th IABMR Annual Meeting, Boston, Massachusetts, USA, November, 2008. (Achieved 1st place in the IABMR Award Competition - In Recognition of Excellent Scientific Study Presentation) 5. Alt-Holland, A., Sowalsky, A., Szwec-Levin, Y., Shamis, Y., Feig, L. and Garlick, J.A. Silencing of FAK and Src kinases normalizes human, 3D tissue models of squamous cell carcinoma harboring E-cadherin-deficient tumor cells. 69th Annual Meeting of the Society for Investigative Dermatology, Montreal, Canada, May, 2009. 6. Alt-Holland, A., Szwec-Levin, Y., Sowalsky, A., Shamis, Y., Feig, L. and Garlick, J.A. Suppression of E-cadherin function leads to deregulation of FAK and Src to direct squamous cell carcinoma progression. AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics, Boston, Massachusetts, USA, November, 2009. 7. Alt-Holland, A., Szwec-Levin, Y., Sowalsky, A., Shamis, Y., Feig, L., and Garlick, J.A. Suppression of E-cadherin function leads to deregulation of FAK and Src to direct squamous cell carcinoma progression. AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics, Boston, MA, USA, November, 2009. 8. Szwec-Levin, Y., Sowalsky, A., Feig, L., Garlick, J.A., and Alt-Holland, A. Depletion of Focal adhesion kinase or Src kinase in fibroblasts stimulates cytokine secretion and promotes tumor cell invasion in bioengineered, three-dimensional human skin equivalents. 6th IABMR Annual Meeting, Boston, MA, USA, November, 2009. 9. Alt-Holland, A., Park, H., Szwec-Levin, Y., Nguyen, A., Sowalsky, A., Shamis, Y., Feig, L. and Garlick, J.A. Normalization of epithelial precancerous tissues through modulation of tumor-microenvironment interactions. AADR, March, 2010. 10. Szwec-Levin, Y., Sowalsky, A., Feig, L., Garlick, J.A. and Alt-Holland, A. The epithelial-Stromal cross talk in tumor microenvironment interactions during incipient squamous cell carcinoma progression. AAE San Diego, April, 2010. 11. D. Kaluma, Szwec-Levin, Y.,H. Hatch, J. Bair, A. Sowalsky, L. A. Feig, J. A. Garlick, A. Alt-Holland Characterizing the effect of FAK and Src down regulation in fibroblasts on epithelial tumor cell invasion in bioengineered, three-dimensional human skin tissues. Building Diversity in Biomedical Sciences for Undergraduates, Tufts University, Sackler School of Graduate Biomedical Sciences for Undergraduates, August, 2010. Oral presentations in conferences: 1. Szwec-Levin, Y., Sowalsky, A., Feig, L., Garlick, J.A. and Alt-Holland, A. FAK/Srcdepleted fibroblasts increase carcinoma cell invasion through elevated cytokine secretion. AADR, Washington, DC, March, 2010 2. Szwec-Levin Y. Investigating the Progression of Squamous Cell Carcinoma in Three-Dimensional Human Skin Tissue Model. Oral presentation, Reunion of class of 1991, July, 2010 The Hebrew University, Hadassah, School of Dental Medicine Publications: 1. Mann J., Gat E., Lubliner D., Malowanczyk C., Szwec Y., Zusman S., and Ela K., Dental underemployment: a study of uncontrolled dental manpower immigration, International Dental Journal (1993) 43 317-322 2. Heling I., Rotstein I., Szwec-Levine Y., Steinberg D., Bacterial and Cytotoxic Effects of Sodium Hypochlorite and Sodium Dichloroisocyanurate Solutions in Vitro. Journal of Endodontics (4/2000) 27/4 278-280 3. Alt-Holland, A., Sowalsky, A.G, Szwec-Levine, Y.,., Shamis, Y., Feig, L., and Garlick, J.A. Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma progression through up-regulation of Src and FAK. Journal of Investigative Dermatology(11/2011) 131, 2306-2315 MEMBERSHIP OF PROFESSIONAL SOCIETIES ההסתדרות לרפואת שיניים בישראל American Association of Endodontists (AAE) האיגוד הישראלי לאנדודונטיה