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Running Head: Borderline Personality Disorder Treatment of Borderline Personality Disorder Using Dialectical Behavior Therapy: A Review of the Literature Mark Fields Wake Forest University 1 Borderline Personality Disorder 2 Abstract The purpose of this literature review is to explore the subject of borderline personality disorder and its treatment with dialectical behavior therapy. Does the literature support using a dialectical behavior therapy approach with borderline personality disorder and with comorbid substance abuse? Dialectical behavior therapy is introduced in the context of its promise as an emerging response to the difficulty in treating borderline personality disorder. The methods section will explain the process of acquisition of the literature used and cited. The primary method was electronic database search, and useful search terms and databases will be summarized. The results of the study will describe the DSM IV diagnostic criteria for the disorder, its high cost of treatment, prevalence, ethnographic statistics, sex differences, and briefly examine causation in the context of Linehan’s biosocial theory. An overview of dialectical behavior therapy’s history, techniques, and its effectiveness in treatment of borderline personality disorder alone and comorbid with substance abuse or dependence indicates that the literature supports the efficacy of this treatment. The discussion further examines dialectical behavior therapy as a treatment for borderline personality disorder, highlighting gaps in the literature, suggesting directions for further study, and discussing the limitations of this study. Borderline Personality Disorder 3 Introduction Borderline personality disorder (BPD) is an Axis II diagnosis and a cluster B personality disorder. BPD presents high comorbidity with other diagnoses, both Axis I and Axis II. It is also commonly associated with substance use and abuse, and individuals with BPD are highly likely to commit self-harming acts including both attempted and completed suicide (American Psychiatric Association, 2000). These facts contribute not only to a disproportionate financial burden on the public in comparison to its relatively low prevalence in the population, but also to a tremendous financial, emotional, and psychological burden on individuals and their loved ones. Sufferers of BPD are prolific users of private and public mental health, social, and hospital services, and professionals and paraprofessionals in these fields will benefit from understanding the characteristics of this disorder. Improving treatment methods and availability and streamlining the process of care for this population could benefit both these individuals and the service providers and systems they depend on. BPD, not unlike other personality disorders, has been notoriously hard to treat successfully. In the past two decades, dialectical behavior therapy (DBT) has emerged as perhaps the most promising treatment developed thus far in addressing the needs of persons with this diagnosis. In particular, DBT has had success in reducing the occurrence of self-harm and suicidal behavior, the latter perhaps being the most dire outcome for any mental health diagnosis (Seligman & Reichenberg, 2012; Freeman, Stone, & Martin, 2004). In addition to presenting an overview of the disorder, this literature review will examine DBT in the context of addressing its success in treatment of BPD in limited comparison to other approaches to treatment of BPD. Focus will be on outcomes and its success in mitigating various symptoms and of the disorder, including suicide and comorbid substance use and dependence. Borderline Personality Disorder 4 Methods The research for this review was primarily conducted through database searches of PsycINFO, PsycArticles, and PubMed. I initially intended to take a broader scope on comparative treatment, rather than focusing on DBT. Intending to get a broad overview of treatments, my first search of PsycINFO started with a first subject line “borderline personality disorder” combined by “AND” with the second subject line “treatment OR therapy OR techniques.” On the first page, this yielded 17 results, 11 of which were specifically addressing dialectical behavior therapy (DBT) as a subject. Combing with “AND” a third line “suicide*” yielded 15 of 20 results with dialectical behavior therapy as the subject, and 2 of the remaining 5 were focused on cognitive behavior therapy, a DBT precursor. These initial results combined with consultation of texts and peers in counseling and related fields solidified my focus on DBT. Moving forward, I searched multiple combinations of terms in these databases, as well as a cursory search of Google Scholar, to try to narrow the results, combining “borderline personality disorder” with various secondary and tertiary subjects including, “dialectical behavior therapy,” “cognitive behavior therapy,” “diagnos*,” “outcome,” “substance use,” “substance dependence,” “substance abus*,” “opioid,” “alcohol,” “self-harm,” “self-mutilation”, “symptom,” “impuls*,” “affect.” After vetting sources for their validity and relevance, I followed the reference lists to older articles, texts, and other sources. In addition, I used texts from the local library and UpToDate, the largest continuously edited online medical text, for general information on BPD and treatments and to look for additional cited references. After reading abstracts or scanning full texts, I tried to isolate those of greatest relevance or soundest method. Unfortunately, many promising sources had to be excluded due to Borderline Personality Disorder 5 unavailability in a free or affordable full-text format. PubMed yielded much useable information, but many items were pay-to-view only or did not include full-text links. Because of this, PsycINFO provided the greatest balance of quality, quantity, and accessibility of the databases linked to Wake Forest’s library. Results According to the DSM-IV (American Psychiatric Association, 2000) Borderline Personality Disorder (BPD) is a cluster B personality disorder. General criteria for a personality disorder of any kind highlight patterns of behavior and inner experience that deviate from cultural expectations. Of four areas: cognition, affectivity, interpersonal functioning, and impulse control, the pattern must be present in at least two for diagnosis of a personality disorder. Although BPD cannot, by definition, be diagnosed until adulthood, diagnostic criteria are likely to emerge in adolescence or childhood. Diagnostic criteria for borderline personality disorder are as follows: A pervasive pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts as indicated by five or more of the following: (1) frantic efforts to avoid real or imagined abandonment. (2) a pattern of unstable and intense interpersonal relationships characterized by alternating between extremes of idealization and devaluation (3) identity disturbance: markedly and persistently unstable self-image or sense of self (4) impulsivity in at least two areas that are self-damaging (e.g., spending, sex, substance abuse, reckless driving, binge eating) Borderline Personality Disorder (5) recurrent suicidal behavior, gestures, or threats, or self-mutilating behavior (6) affective instability due to marked reactivity of mood (e.g., intense episodic dysphoria, irritability, or anxiety usually lasting a few hours and only rarely more than a few days) (7) chronic feelings of emptiness (8) inappropriate, intense anger or difficulty controlling anger (e.g., frequent displays of temper, constant anger, recurrent physical fights) (9) transient, stress-related paranoid ideation or severe dissociative symptoms. (American Psychiatric Association, 2000, p. 706) Borderline personality is estimated to affect between 1% and 2% of the general population at any given time with a lifetime prevalence of about 6%, but is estimated to account for as much as 20% of psychiatric inpatients and 9.3% of outpatients (Silk, 2013a; Seligman & Reichenberg, 2012; Chapman, 2010; American Psychiatric Association, 2000). Almost all persons with BPD will use some type of outpatient services. The cost of treatment and of lost productivity for these individuals is on average substantially higher than for non-personality disorders and diagnoses, and of other personality disorders only obsessive-compulsive personality disorder has a similar average cost per year (Silk, 2013a). Results from multiple studies estimate the rate of death by suicide for this population around 10%, and according to Oldham as cited by Seligman and Reichenburg (2012), 60-70% will attempt suicide. Hospitalization for self-inflicted physical trauma extends the cost to the individual and society beyond treatment, while further destabilizing the life and mental state of the individual. Understanding borderline personality disorder is of significant importance to counselors, as we may encounter these individuals, regardless of counseling specialty. Causation of BPD is yet to 6 Borderline Personality Disorder be determined. Correlations between childhood abuse and trauma, genetics, and biological factors including brain chemistry have been studied, but no single element or combination can be proved as a cause. Linehan’s biosocial model suggests these individuals may be naturally emotionally sensitive, unable to regulate response, and slow to return to a baseline (Linehan, 1993; Hampton, 1997; Crowell, Beauchaine, & Linehan, 2009). Precursors to BPD may emerge due to an invalidating developmental context in which extreme responses are simultaneously reinforced and chastised and “the child does not learn how to understand, label, regulate, or tolerate emotional responses and instead learns to oscillate between emotional inhibition and extreme emotional lability” (Crowell, Beauchaine, & Linehan, 2009, p. 496). If accurate, this would explain why there is a positive correlation between childhood trauma and abuse and BPD, while also demonstrating that these are not necessary conditions of its development. There is little in the literature suggesting any significant statistical correlation between prevalence of BPD and race, ethnicity, income, or even marital status (Chapman, 2010; Silk, 2013; Paris & Zweig-Frank, 2001). However, a large epidemiological study by Grant, et al. (as cited in Crowell, Beauchaine, & Linehan, 2009, p. 502) suggests that there may be significant racial and ethnic differences, and that the general prevalence may be as high as 5.9%. Women are three times as likely to seek care, which may account for most references declaring that females represent the significant majority of persons with BPD, but other evidence suggests that prevalence between the sexes in the general population could be either equivalent or influenced by ethnicity (Silk, 2013a; Seligman & Reichenberg, 2012; Crowell, Beauchaine, & Linehan, 2009; Paris & Zweig-Frank, 2001). BPD has been shown to affect men and women differently, as men with BPD are more prone to substance abuse and comorbidity with other personality 7 Borderline Personality Disorder disorders, and women with BPD are more likely to suffer from PTSD and eating disorders (Silk, 2013a). A range of therapies have demonstrated some success in the treatment of BPD in various contexts, but there is much empirical evidence for the comparative efficacy of dialectical behavior therapy, which was one of the only therapeutic methods shown to significantly reduce suicidal behavior and ideation as well as mediate substance use disorder in BPD patients (Silk, 2013b; McMain, Guimond, Streiner, Cardish, & Links, 2012; Bedics, Atkins, Comtois, & Linehan, 2012; Axelrod, Perepletchikova, Holtzman, & Sinha, 2011; Neacsiu, Rizvi, & Linehan, 2010; Linehan, et al., 2006; Freeman & Martin, 2004). Dialectical behavior therapy was originally developed by cognitive behavior therapist Dr. Marsha Linehan to address patients exhibiting parasuicidal behaviors, and though she did not intend originally to work specifically with borderline personality disorder, in the course of exploring treatment for suicidal behaviors she found that DBT showed promise as a treatment for individuals with BPD (Linehan, 1993; Reynolds & Linehan 2002; Hampton, 1997). DBT “is rooted in standard cognitive and behavioral protocols, and it remains, first and foremost, a problem-solving, behavior therapy approach” (Reynolds & Linehan, 2002, p. 621). Although rooted in cognitive behavior therapy, DBT incorporates ideas as well as mindfulness practices from Zen Buddhist and Western transcendental philosophy to focus largely on the dualistic qualities that have become inherent to the patient’s thinking and behavior (Linehan, 1993; Reynolds & Linehan 2002; Neacsiu, Rizvi, & Linehan, 2010). Reynolds and Linehan (2002, p. 621) assert that “the balance between acceptance and change is the overarching dialectic of treatment.” While rooted in cognitive behavior therapy, Linehan (1993) wished to improve upon this treatment method for persons expressing suicidal tendency. Behavioral approaches to counseling 8 Borderline Personality Disorder and psychology are often criticized for treating symptoms or behavior while ignoring aspects of causation and lacking emphasis on the therapeutic relationship, but “in contrast to many behavioral approaches, DBT places great emphasis on the therapeutic relationship as a mechanism of change” (Reynolds & Linehan, 2002, p. 624). DBT employs four modes of treatment: individual psychotherapy, group therapy focused on skills training, weekly collaboration between therapists and other professionals that include monitoring the counselor’s own mental health, and telephone consultation with the client between sessions (Linehan, 1993; Hampton, 1997). These elements are meant to enhance client/counselor relations through frequent and meaningful contact and reduce early termination and other negative reactions to therapy. DBT attempts to reverse maladaptive patterns by concurrently validating a client’s emotional and affective responses while replacing them with a new acceptable pattern of thought and behavior. Neacsiu, Rizvi, and Linehan (2010) demonstrated that developing and utilizing these adaptive skills with BPD persons fully mediated suicide attempts, anger control, and depression and partially mediated self-harm at a four-month follow up compared to a control group. DBT has shown promise not only in the treatment of BPD, but also in use for comorbid BPD and substance use disorder, and for substance abuse in general (Bornovalova & Daughters, 2007; McMain, Sayrs, Dimeff, & Linehan, 2007; Rosenthal, Lynch, & Linehan, 2005). Substance abuse treatment alone for BPD and comorbid substance use disorder (SUD) can be ineffective in mitigating either disorder (McMain, Sayrs, Dimeff, & Linehan, 2007; Rosenthal, Lynch, & Linehan, 2005). Comparing DBT to a 12-step treatment method for individuals with comorbid BPD and opiate abuse, Linehan, et al. (as cited in Rosenthal, Lynch, & Linehan, 2005, p. 617) stated that “in the last 4 months of treatment, those in the DBT-SUD condition maintained 9 Borderline Personality Disorder 10 treatment gains, whereas those in the comprehensive validation condition had a significant increase in opiate use during this period.” In this case, the 12-step treatment actually had detrimental results versus positive gains in the group that received DBT. In a separate randomized trial, Linehan, et al. (as cited in Rosenthal, Lynch, & Linehan, 2005) obtained positive comparative results at a 16 month follow-up for DBT over treatment as usual not only in reduction of substance abuse behaviors, but also in positive measures of global and social adjustment. Discussion The findings regarding the use of dialectical behavior therapy with borderline personality disorder appear to be overwhelmingly positive. Of particular importance is evidence that DBT can reduce the frequency of suicide. Further evidence supporting DBT as a treatment for comorbid substance abuse is also of import to this population. A level of skepticism should remain, as there is not yet available data on the longer term benefits of the treatment. Few studies with extreme long term follow-up have been conducted with the BPD population in general, but Paris and Zweig-Frank’s (2001) 27-year follow up study implied that for most individuals the disorder slowly dissipates in intensity. Perhaps sample groups for research studies should be controlled for age, as data indicates that improvements occur naturally into middle and late adulthood. Of the patients on whom they were able to gather data throughout Paris and Zweig-Frank’s study, most at the 27-year mark no longer retained the diagnostic criteria for the disorder, though lesser diagnoses and certain affects remained for many. Borderline Personality Disorder Suggested areas of continued research include isolating the aspects and techniques of DBT that alleviate the symptoms of BPD and/or are effective in decreasing substance use. With the exception of the study by Neacsiu, Rizvi, and Linehan (2010), I could find few examples of empirical design to test specific aspects of the treatment. Many studies focused specifically on the female population because, as referenced earlier, the disorder is commonly accepted to be more common in women. More research on men with the disorder would shed light on some of the gender differences between these populations and possibly could suggest alternative treatment methods for the sexes. I would also like to investigate strategies to improve interpersonal relationships for the BPD population, as Paris and Zweig-Frank (2001) found over half of their cohort living alone or not in an intimate relationship after 27 years. In essence, the literature supports the continued use of dialectical behavior therapy as an effective treatment for borderline personality. Although more data should and will be collected and analyzed through its continued application, current indications suggest it should remain an accepted approach. Until causation for the disorder is fully understood, preventative measures and responsive treatments may not be perfected. Continued study of the relevancy of Linehan’s biosocial theory could augment the current information. The data currently available suggests DBT is an effective treatment and appears to be superior to some other treatments, but this should not necessarily exclude other approaches. 11 Borderline Personality Disorder 12 References American Psychiatric Association (2000). Diagnostic and statistical manual of mental disorders (4th ed., Text Revision). Washington, DC: Author Axelrod, S. R., Perepletchikova, F., Holtzman, K., & Sinha, R. (2011). Emotion regulation and substance use frequency in women with substance dependence and borderline personality disorder receiving dialectical behavior therapy. The American Journal of Drug and Alcohol Abuse, 37(1), 37-42. doi:10.3109/00952990.2010.535582 Bedics, J. D., Atkins, D. C., Comtois, K. A., & Linehan, M. M. (2012). Treatment differences in the therapeutic relationship and introject during a 2-year randomized controlled trial of dialectical behavior therapy versus nonbehavioral psychotherapy experts for borderline personality disorder. Journal of Consulting and Clinical Psychology, 80(1), 66-77. doi:10.1037/a0026113 Bornovalova, M. A., & Daughters, S. B. (2007). How does dialectical behavior therapy facilitate treatment retention among individuals with comorbid borderline personality disorder and substance use disorders?. Clinical Psychology Review, 27, 923-943. doi:10.1016/j.cpr.2007.01.013 Chapman, A. L. (2010). Borderline personality disorder. In D. McKay, J. S. Abramowitz, S. Taylor (Eds.), Cognitive-behavioral therapy for refractory cases: Turning failure into success (pp. 347-367). Washington, DC US: American Psychological Association. doi:10.1037/12070-016 Crowell, S. E., Beauchaine, T. P., & Linehan, M. M. (2009). A biosocial developmental model of borderline personality: Elaborating and extending Linehan’s theory. Psychological Bulletin, 135, 495-510. doi:10.1037/a0015616 Borderline Personality Disorder Freeman, A., Stone, M. H., & Martin, D. (2004). 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