Download Term 1 Unified #2 - Website of Neelay Gandhi

FIRST TERM UNIFIED QUIZ #2
APRIL 14, 2003
HISTOLOGY
1.
Testosterone is produced by:
A.
B.
C.
D.
E.
2.
The proximal tubules of the kidney:
A.
B.
C.
D.
E.
3.
is a component of the basement membrane of the alveolar epithelium
Is produced by alveolar macrophages
Coats the nasal epithelium
Is produced by Type I pneumocytes
Decreases the surface tension at the epithelial-air surface
The marginal zone of the spleen is:
A.
B.
C.
D.
E.
6.
Are found primarily in thick skin
Are holocrine glands
Secrete fluid composed primarily of protein and water
Are located in the stratum germanitivum
Have all of the above features
Surfactant:
A.
B.
C.
D.
E.
5.
Exhibit numerous microvilli at the cell surface
Are composed of simple squamous epithelium
Secrete glucose and amino acids into the glomerular filtrate
Lack a basal lamina
Are continuous with collecting ducts
Sebaceous glands:
A.
B.
C.
D.
E.
4.
Sertoli Cells
Type A Spermatogonia
Type B Spermatogonia
Spermatids
Interstitial cells of Leydig
Located in the PALS
Located in the capsule
A site where immune reactions occur
Avascular
Rich in adipose tissue
The bloods vessels that respond to the reduction of withdrawal of progesterone, and that supply the
functional layer of the endometrium are:
A.
B.
C.
D.
E.
Spiral arteries
Straight arteries
Arcuate arteries
High endothelial venules (HEVs)
The uterine artery
7.
The zona pellucida is a site within developing ovarian follicles. The zona pellucida:
A.
B.
C.
D.
E.
8.
Hormones classified as glucocorticoids (like cortisol) are produced in the adrenal cortex in a layer called
the:
A.
B.
C.
D.
E.
9.
Glomerulosa
Fasciculata
Reticularis
Chromaffin
Medulla
The cells that produce the hormone called calcitonin are:
A.
B.
C.
D.
E.
10.
stains dark blue with H&E stain
Is present in primordial follicles
Is produced by cells of the theca externa
Facilitates contact between the oocyte and follicle cells
Lies within the tunica albuginea
Principle or follicle cells of the thyroid gland
Principle or follicle cells of the parathyroid gland
Parafollicular or “clear” cells of the thyroid
Oxyphil cells of the parathyroid
Pinealocytes
The epithelial reticular cells (ERCs) contribute to several important functions in the immune system. They
are located only in the:
A.
B.
C.
D.
E.
Palatine tonsil
Lymph nodules
Lymph nodes
Lymphatic vessels
Thymus
EMBRYOLOGY QUESTIONS
11.
Which of the following statements about the auditory ossicles is true? They
A.
B.
C.
D.
E.
12.
Regarding the metopic suture
A.
B.
C.
D.
E.
13.
musculature and connective tissue of the trigone of the bladder
the canal of Epididymis
vas (ductus) deferens
ejaculatory duct
all of the above
The primordial germ cells in the gonads are derived from:
A.
B.
C.
D.
E.
16.
clavicle/intramembranous ossification
oxycephaly/premature fusion of sagittal suture
muscles of facial expression/first branchial arch
third branchial arch/mandibular nerve
osteoclasts/bone forming cells
The mesonephric duct gives rise to
A.
B.
C.
D.
E.
15.
it is located between the frontal and parietal bones
it is located between the two halves of the frontal bone
it is seen only in the fetal skull
it can normal be seen in the adult skull
All of the above are true
Which one of the following pairs is correctly matched?
A.
B.
C.
D.
E.
14.
Develop by intramembranous ossification
Are derived from the Meckel’s cartilage
Are derived from the Reichert’s cartilage
Are derived from both the Meckel’s cartilage and Reichert’s cartilage
Form a part of the neurocranium
surface Mesothelium over the gonadal swelling
intermediate mesoderm
yolk sac endoderm
mesonephros
yolk stalk
A 19 year old male comes to the clinic with a painless cystic swelling on the right side of the neck at the
anterior border of the sternomastoid. The condition is diagnosed as branchial cyst. The branchial cyst
results due to failure of:
A.
B.
C.
D.
E.
development of the second branchial arch
development of second branchial pouch
closure of second branchial groove
obliteration of cervical sinus
formation of cervical sinus
17.
Which of the following participates in the development of tongue?
A.
B.
C.
D.
E.
18.
A part of the gubernaculums is represented in the adult female by the:
A.
B.
C.
D.
E.
19.
broad ligament of the uterus
hymen
suspensory ligament of the ovary
ovarian ligament
mesosalpinx
The intermaxillary segment is formed by the fusion of:
A.
B.
C.
D.
E.
20.
copula
tuberculum impar
caudal part of hypobranchial eminence
second branchial arch
occipital Myotomes
maxillary prominences
medial nasal prominences
lateral nasal prominences
medial and lateral nasal prominences
maxillary and lateral nasal prominences
Treacher Collins syndrome results due to a defective development of:
A.
B.
C.
D.
E.
ultimobranchial body
third and fourth branchial pouches
first branchial arches
third branchial arch
fourth branchial arch
GROSS ANATOMY
21.
Muscles in the anterior compartment of the leg receive most of their arterial blood supply directly from
branches of the ___________________ artery.
A.
B.
C.
D.
E.
22.
Paralysis of the tibialis posterior muscle will results in a weakness in:
A.
B.
C.
D.
E.
23.
B.
C.
D.
E.
as it passes through the cribriform fascia of the thigh
immediately deep to the sartorius muscle
as it joins the deep femoral vein in the femoral triangle
as it passes deep to the inguinal ligament
at the adductor hiatus of the adductor magnus muscle
In its normal placement with the pelvic cavity, the uterus lies in a _________________ position.
A.
B.
C.
D.
E.
26.
the terminal branches of the internal pudendal arteries provide the main arterial supply of the
erectile tissues of the penis
increased parasympathetic activity during sexual arousal increases blood volume in the erectile
tissues of the penis
penile erection occurs as a consequence of the engorgement of the cavernous sinuses in the
corpora cavernosa of the penis
secretions from the seminal vesicles and prostate gland contribute to the composition of semen
during emission
All of the above are correct
The femoral vein becomes the external iliac vein:
A.
B.
C.
D.
E.
25.
extension of the toes
flexion of the toes
dorsiflexion of the foot
eversion of the foot
inversion of the foot
Which of the following statements concerning penile erection and ejaculation is/are correct?
A.
24.
popliteal
anterior tibial
posterior tibial
fibular (peroneal)
dorsalis pedis
prolapses
anteverted – retroflexed
retroverted – anteflexed
retroverted – retroflexed
anteverted – anteflexed
The glans clitoris:
A.
B.
C.
D.
E.
sends most of its lymphatic drainage into inguinal lymph nodes
does not have a homologue in the male
is the distal continuation of the corpora cavernosa
receives sensory innervation from branches of the genitofemoral nerve
is correctly described in all of the above
27.
The biceps femoris muscle:
A.
B.
C.
D.
E.
Inserts on the fibula
Acts in flexion of the thigh
Is innervated by the femoral nerve
Forms one boundary of the femoral triangle
Is correctly described in all of the above
28.
The pain and itching from a mosquito bite in the skin overlying the belly of the rectus femoris muscle is
carried toward the CNS by branches of the _______________ nerve.
A.
B.
C.
D.
E.
femoral
sural
lateral femoral cutaneous
posterior femoral cutaneous
saphenous
29.
The muscle forming the lateral border of the carotid triangle receives its motor innervation from the
branches of the _____________________ nerve.
A.
B.
C.
D.
E.
30.
hypoglossal
trigeminal
ansa cervicalis
spinal accessory
vagus
Forming a portion of the viscerocranium is the __________ bone.
A.
B.
C.
D.
E.
hyoid
ethmoid
vomer
sphenoid
frontal
BIOCHEMISTRY
31.
A researcher produces a “knock-out” mouse in which both copies of the gene for PI 3 kinase
(Phosphatidylinositol 3-kinase) are disrupted. Which of the following processes will be most affected?
A.
B.
C.
D.
E.
32.
Cystic fibrosis is caused by mutation in the gene for a protein which has been named CFTR. Which of the
following proteins shows the greatest sequence homology to CFTR?
A.
B.
C.
D.
E.
33.
Glycophorin
Multi-Drug-Resistance Protein
Glucose transporter GLUT-2
The protein which is deficient in Tay-Sachs disease
Apolipoprotein E
Carnitine is involved:
A.
B.
C.
D.
E.
34.
Release of Ca2+ from liver ER in response to glucagons
Synthesis of sphingomyelin in regenerating nerve
Inhibition of glycogen synthase kinase in response to insulin
Activation of membrane associated phospholipase C
Activation of hormone-sensitive lipase in adiposities
in transporting short chain fatty acids into the mitochondrial matrix
in transporting fatty acids into the ER, where they can undergo desaturation
in the conversion of acetyl-CoA to ketone bodies
in transporting long chain acyl groups into the mitochondrial matrix
the allosteric regulation of acetyl-CoA Dehydrogenase
Deficiency of which of the following enzymes is associated with elevated serum triacyglycerol (TAG)
levels?
A.
B.
C.
D.
E.
Lipoprotein lipase
Acetyl-CoA Carboxylase
Pancreatic lipase
Fatty acid synthase
Phosphatidate phosphohydrolase
35.
A 40 year old man made a good recovery following a myocardial infarction. Lovastatin was prescribed by
his cardiologist. Which of the following will be a result of his therapy?
A.
B.
C.
D.
E.
36.
Reduced plasma HDL levels
Elevated plasma cholesterol levels
Excessive bile secretion
Reduced plasma LDL levels
Reduced hepatic TAG synthesis
Which of the following statements concerning the B-form of DNA is FALSE?
A.
B.
C.
D.
E.
The two DNA chains run in opposite directions
G on one strand makes 3 hydrogen bonds with an A on the other strand
The double-helix makes one complete turn every 10 nucleotides
Most of the DNA found naturally in cells exist in the B-form
Nucleotides in the individual chains are joined by 3’,5’-phosphodiester linkages
37.
Which of the following proteins or activities is responsible for removal of RNA primers during DNA
replication in E.Coli?
A.
B.
C.
D.
E.
38.
Which of the following statements concerning transcription is TRUE?
A.
B.
C.
D.
E.
39.
DNA gyrase
3’--->5’ exonuclease of Pol I
5’--->3’ exonuclease of Pol I
telomerase
rep protein
RNA polymerases require an RNA primer in order to function
Sigma factor is required for termination of transcription in prokaryotes
Three RNA polymerases are involved in transcription in eukaryotes
In prokaryotes transcription starts at the Shine-Dalgarno sequence
Removal of introns from the primary transcript occurs in prokaryotes
Which of the following statements concerning the genetic code is FALSE?
A.
B.
C.
D.
E.
it is an overlapping code
it is a degenerate code
it uses no punctuation except for stop and start signals
It is a triplet code
61 codons code for amino acids
40.
The toxin produced by Corynebacterium diphtheriae, the cause of diphtheria, interferes with translation by
its effect on which of the following protein factors?
A.
B.
C.
D.
E.
EF-Tu
RF-2
IF-2
Rho factor
EF-2
ANSWER KEY
Histology
1. E
2. A
3. B
4. E
5. C
6. A
7. D
8. B
9. C
10. E
Embryology
11. D
12. B
13. A
14. E
15. C
16. D
17. E
18. D
19. B
20. C
Anatomy
21. B
22. E
23. E
24. D
25. E
26. A
27. A
28. A
29. D
30. C
Biochemistry
31. C
32. B
33. D
34. A
35. D
36. B
37. C
38. C
39. A
40. E