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HIV/AIDS STUDY GUIDE Spring 2016 Nursing 1229 1. What are the modes of transmission of HIV/AIDS? ( Instructor) Body fluids containing HIV or infected CD4 lymphocytes Blood, seminal fluid, vaginal secretions, amniotic fluid, and breast milk Most prenatal infections occur during delivery Casual contact does not cause transmission Breaks in skin and mucosa increase risk 2. High risk behaviors associated with contacting HIV/AIDS. (Instructor) Sharing infected injection equipment Having sexual relations with infected individuals Infected mother passing HIV to her baby 3. What are the stages of HIV/AIDS disease? (Instructor) Primary Infection (Stage 1): period from infection with HIV to the development of anti-bodies. Person may test negative however they are highly contagious and the virus is rapidly replicating throughout their bodies, making their viral loads high. They may have clinical symptoms that mimic a viral illness (flu: fever, flu, rash) which last 1 – 2 weeks. CD4 t+ lymphocytes are being destroyed. Primary infection: Category A CD4+T cell count >500 S/S: non-flu like, lymphadenopathy, pharyngitis, skin rash, myalgias /arthralgias HIV asymptomatic (Stage 1): Category A CD4+T cell count > 500 S/S: few if any, may be in this stage for 8-10 years HIV symptomatic (Stage 2): Category B CD4+T cell count 200-499 S/S: oral candidiasis (most common), diarrhea exceeding 1 mo., herpes zoster, PID, peripheral neuropathy AIDS (Stage 3) Category C CD4+T cell count <200 S/S: GI candidiasis, cancers, CMV, MAC 4. Identify and discuss the 3 aspects of Caring for HIV/AIDS The 3 aspects of care are: A. Prevention (priority 1): Standard precautions: see Chart 52-4 Practice safer sex practices and safer behaviors Abstain from sharing sexual fluids Reduce the number of sexual partners to one Always use latex condoms; if allergic to latex, use non latex condoms See Chart 52-2 Do not share drug injection equipment Blood screening and treatment of blood B. Early detection Critical to the treatment of and survival rate of those infected with the disease C. Ongoing treatment Patients with HIV/AIDS must adhere to the treatment prescribed by their doctor and if followed it may increase their life expectancy by years 5. What diagnostic tests are used to diagnose and track the immune system of persons with HIV? Diagnostic test EIA: identifies antibodies Western blot: used to confirm positive EIA Ora-Sure: uses saliva to detect HIV-1 Ora-Quick: uses less than a drop of blood to detect HIV-1 Tracking immune system Viral load test: tracks response to treatment for HIV (how the patient’s body is responding to meds) 6. Class of drugs used to treat HIV infection? HARRT”s (action of each HAART; see pictures) a. NRTI’s (block DNA activity) : didanosine (Videx), zalcitabine (Hivid), zidovudine (AZT) b. NNRTI’s(terminates viral replication): efavirenz (Sustiva) c. FI’s: (target cells during attachement of HIV to destroy them) enfuvirtide (Fuzeon) d. Use of combination therapy (more than one drug) 7. Clinical manifestations seen in a client with HIV/AIDS for each of the following body systems: (see text) e. Respiratory f. Gastrointestinal g. Oncologic h. Neurologic i. Depressive j. Integumentary k. Endocrine l. Gynecologic 8. Medical management (medication therapy) of the following opportunistic infections (see text) m. Pneumocystis pneumonia: n. Mycobacterium avium complex o. Cryptococcal meningitis p. Cytomeglavirus retinitis q. Other infections 9. Medical management (medication therapy) is used for the following r. Prevention/treatment of the following opportunistic infections i. PCP ii. MAC iii. Meningitis iv. CMV s. Antidiarrheal therapy t. Chemotherapy u. Antidepressant therapy v. Nutrition therapy Management focuses upon the treatment of specific manifestations and conditions related to the disease Hepatotoxicity associated with certain protease inhibitors may limit the use of these agents, especially in patients with underlying liver dysfunction 10. Areas of assessment that would be important for the nurse caring for a client diagnosed with HIV/AIDS Skin Integrity Conduct frequent routine assessment of skin and mucosa Encourage patient to maintain balance between rest and activity Reposition at least every two hours and as needed Use pressure reduction devices Instruct patient to avoid scratching Use gentle, nondrying soaps or cleansers Avoid adhesive tape Provide perianal skin care Promoting Usual Bowel Pattern Assess bowel pattern and factors that may exacerbate diarrhea Avoid foods that act as bowel irritants, such as raw fruits and vegetables, carbonated beverages, spicy foods, and foods of extreme temperatures Small, frequent meals Administer medications as prescribed Assess and promote self-care strategies to control diarrhea Activity Intolerance Maintain balance between activity and rest Instruction regarding energy conservation techniques Relaxation measures Collaboration with other members of the health care team Maintaining Thought Processes Assess mental and neurologic status Use clear, simple language if mental status is altered Establish and maintain a daily routine Use orientation techniques Ensure patient safety and protect from injury Implement strategies to maintain and improve functional ability Instruct and involve family in communication and care Nutrition Provide dietary consultation Monitor weight, I&O, dietary intake, and factors that interfere with nutrition Control nausea with anti-emetics Provide oral hygiene Treat oral discomfort Administer dietary supplements May require enteral feedings or parenteral nutrition Decreasing Isolation Promote an atmosphere of acceptance and understanding Assess social interactions and monitor behaviors Allow patient to express feelings Address psychosocial issues Provide information related to the spread of infection Educate ancillary personnel, family, and partners Other Interventions Improve Airway Clearance Use semi-Fowler's or high-Fowler’s position Pulmonary therapy; coughing and deep breathing; postural drainage; percussion; and vibration Ensure adequate rest Pain Administer medications as prescribed Provide skin and perianal care