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Advanced Biomedical Imaging Dr. Azza Helal A. Prof. of Medical Physics Faculty of Medicine Alexandria University Intended learning outcomes of the course (ILOS) To understand physical principles of imaging modalities. Aiming to apply these modalities in a safe and effective way. Gamma imaging & Tomography with Radionuclides A medical imaging that uses radioactive isotopes and depends on process of radioactive decay in diagnosis. By counting radioactivity & its distribution in the organ. So it is capable of detecting physiological function fo .snagro Gamma Camera Planar Imaging single projection view no image reconstruction is required Tomography with Radionuclides Positron Emission Tomography (PET) Single Photon Emission Tomography )SPECT) PET CT images show metastases to left supraclavicular lymph node a and to liver b Comparison of different imaging modalities 1. Projection views 2. Ionizing radiation 3. Speed 4. Contrast resolution 1. Projection views Limited visualization Plain x ray & Isotope scan Flexible imaging planes Cross-section views CT & MRI Flexible imaging planes with MRI. MRI angiography 2. Ionizing radiation Plain x - ray, CT & isotope scan 3. Speed US Plain x ray CT MRI Isotope scan Fast Slow 4. Contrast Plain X Ray CT Physical and electron density US Transmitting & receiving high frequency sound wave Isotope scan Uptake of radioactive tracer MRI Transmitting & receiving radiowaves inside a high magnetic field (Water concentration & Magnetic properties) Contrast resolution Plain x ray & CT reflect bone contrast MRI reflects soft tissue contrast Assignments One student will be selected for assignment Suggested Readings David Sutton’s Radiology Physics for medical imaging by RF Fare & PJ Allisy-Roberts. Question Mention different components of x ray tube?