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vel AS & A le Had a look Nearly there Nailed it! 4.2.2e, i Evidence for evolution Evolution is the theory that the differences between modern living organisms are because of changes that happened under the influence of natural selection over a very long period of time. Darwin and Wallace Evidence for evolution In the mid-1800s, Charles Darwin and Alfred Russel Wallace independently came up with a theory of evolution by natural selection. Natural selection is a mechanism to explain how evolution could have occurred. The two men collaborated and co-published a paper in 1858. Darwin published his book, ‘On the Origin of Species’ in 1859. There is an overwhelming amount of evidence for evolution, from different sources. •The fossil record – we can examine extinct species and compare ancient organisms with modern ones. The age of the fossils can be measured by dating the rocks that they are found in. The fossil record gives us the fossils in chronological order. Some species, such as the horse, have an entire fossil record, showing all of the intermediate forms. Evolution of resistance Evolution in some species has implications for humans. This can be seen in resistance to chemicals. As we invent new pesticides to kill pests on crops, some of the pests can develop pesticide resistance. This means that there will be less yield from the crop. The same thing happens with bacteria and antibiotics, as certain bacteria develop antibiotic resistance. Look back at page 77 for a reminder. Eohippus Oligohippus Merychippus Pliohippus Modern horse •DNA – the DNA sequences of species can be compared to see how closely related species are. Species A - G C C A T A A C C T G A G G Species B - G C C A T A T A C T G A G G Species C - G C C A C A T A G T G A G G Species D - G C C A C A T A G T A A G G - The arrows show the bases that are different across species. •Molecular evidence – the amino acid sequence of common proteins, such as cytochrome c, can be compared to see how closely related species are. Cytochrome c is an essential protein involved in respiration and is common to almost all organisms. Suggest what could happen in the future if no new antibiotics are found. (4 marks) increased antibiotic resistance infections fail to be treated, even with multiple antibiotics increased death from bacterial infection increased use of older techniques / salt bathing / maggots or modern techniques such as bacteriophages / disinfectants / antiseptics 1 From the DNA sequences above, explain which two species are the most closely related. 2 Explain the problems with relying on the fossil record for evidence of evolution. 88 (2 marks) (3 marks)