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Medication Administration Stephanie Stevens, MSN, RN, CNE Naming of Medications A medication can have as many as three different names Chemical Generic Trade or Brand Classification of Medications Medication classification can indicate the: effect of the medication on a body system. symptoms that the medication relieves. medication’s desired effect. Medication Forms Manufacturers make many medications in several forms such as tablets, capsules, elixirs, and suppositories. When administering a medication, be certain to use the proper form. SeeTable 19-2 “Drug Preparations”, p. 401 Distribution Systems Special areas used for stocking and dispensing medications (carts, rooms, cabinets, storage units in patient’s rooms) Distribution Systems Types of Systems Unit-Dose Automated Medication-Dispensing Self-Administered Supply Bar code Medication Administration Types of Distribution Systems Unit Dose System Portable carts w/drawers Keep a 24-hour supply of meds for each patient Each tablet or capsule is individually wrapped May be a “bingo” card Also contains limited amounts of PRN medication Designed to reduce number of medication errors and saves steps in dispensing medications Types of Distribution Systems Automated-Medication Dispensing System Contains routine, PRN, controlled substances Useful for the control of narcotics Individual security code for access Select pt’s name, desired drug, and route System dispenses desired med, records it, and charges it Types of Distribution Systems Bar Code Medication Administration Uses a laptop computer, handheld laser scanner, and bar codes Improves patient safety by adhering to the rights of medication administration Types of Distribution Systems Self-Administered Supply Stored at patient’s bedside Allows for patient independence and responsibility Allows for evaluation of patient adherence and safe medication management before discharge Nonprescription and Prescription Medications Nonprescription Prescription Herbs & Other Botanicals Components of Medication Orders Patient’s full name Date and time the order is written Name of the medication Dosage of the medication Route of administration Time and frequency of administration Purpose or indication for use Signature of the prescriber Types of Orders Five common types of medication orders based on the frequency or urgency of the order Routine PRN Standing Protocols Single Stat Types of Orders Routine Orders Orders carried out until the health care provider cancels it by another order or until a prescribed number of days elapse May indicate a final date or number of dosages Types of Orders PRN Orders Medications given only when the patient requires it Use subjective & objective assessment to determine its need Usually has set time intervals to be given Document: Assessment data you used to determine the need of the medication Evaluate the effectiveness of the medication Types of Orders Standing Protocols Administered in specific situations with criteria for administration Usually used for patients on a particular unit Types of Orders Single Orders Given only once at a specified time Common for preoperative medications or diagnostic examinations www.ibiblio.org Types of Orders Stat Order Medication given immediately & only once Usually written in emergency situation when there is a sudden change in patient’s condition Types of Orders Now Order More specific than a stat order Administered quickly, but not immediately Up to 90 minutes to administer the medication Only administer now medications one time Receiving Medication Orders Verbal Order Medication or treatment order received in the presence of the prescriber Enter the order to the pt’s medical record & transcribe them the same way as if the prescriber wrote them himself Telephone Order Medication or treatment orders the prescriber gives over the telephone TJC requires the nurse who takes the order to read back the complete order after entering it on the patient’s chart. Receiving Medication Orders Order required before administration of drug Only to be given verbally or by telephone by the prescriber to the nurse when written or electronic communication is not possible Correct Transcription and Communication of Orders Once you receive and “process” a medication order, place the order on the MAR or eMAR. Includes Pt’s name Room/bed number Names, dosages, routes and frequencies of med Correct Transcription and Communication of Orders As a nurse, you complete or update the MAR Nurse checks all medication orders for accuracy and thoroughness. If an order seems incorrect, verify with prescriber. When you give the wrong medication or incorrect dose, YOU are legally responsible for the error. Legal Aspects of Med Administration Food & Drug Administration Nurse Practice Acts Institutional Medication Policies Patients’ Rights Controlled Substances Act Substance Abuse Pharmacokinetics What is pharmacokinetics? It is the study of how a medication enters the body. Four Phases Absorption Distribution Metabolism Excretion www.thebody.com Absorption Passage of medication molecules into the blood from the site of administration Influential Factors Route Ability to dissolve Blood flow to the site Food Absorption-Route of Administration Each route has a different rate of absorption Skin Oral Mucous membranes & respiratory airways Intravenous Absorption-Ability to Dissolve Depends largely on its form of preparation Absorption-Food Presence/absence of food in the stomach affects absorption Distribution After absorption, the medication is distributed to organs and tissues and to its specific site of action Factors affecting distribution Circulation Membrane permeability Protein binding Distribution-Circulation Medication enters the bloodstream and it is carried to specific tissues and organs. How fast it gets to the specific area depends on its vascularity Distribution-Membrane Permeability Some membranes serve as barriers to the passage of medications. Older adults are very susceptible. Some membranes are non-selective. Distribution-Protein Binding The degree to which medication bind to serum proteins e.g., albumin affects medication distribution. Medications bound to albumin do not exert any pharmacological activity. Unbound or free molecules are considered the active form of the drug. Older adults, and patients with liver disease or malnutrition have decreased albumin causing more unbound medication and increasing risk for toxicity. Metabolism Also known as biotransformation Occurs under the influence of enzymes that detoxify and transform toxic substances Liver is the primary organ for metabolism If there is a decrease in liver function, the body eliminates med more slowly increasing risk for toxicity resulting in need to decrease dosage. Excretion Process of removing the drug or its metabolites from the body Chemical make up of the drug determines which organ excretes the medication Kidneys are primary organ for excretion process. Renal impairment increases risk for toxicity resulting in need to decrease dosage. Types of Medication Action— Therapeutic Effects Intended or desired physiological response of a medication Each medication has a desired therapeutic effect Can have many therapeutic effects Types of Medication Action— Therapeutic Effects It is important to know the expected therapeutic effect of each medication the patient receives Types of Medication ActionAdverse Effects Undesired, unpredictable, unintended responses to medication. May not have been discovered during the drug’s clinical trials Medication MUST BE discontinued Obligation to report the adverse reaction Types of Medication Action Side Effects A predictable and often unavoidable secondary effect produced at a usual therapeutic dose. Usually discovered during clinical drug testing May or may not be harmful Prescriber may D/C the med if the side effects outweigh the benefits of the medication. Common SE Types of Medication ActionTolerance When an increased dosage of medication is required in order to achieve the same effect as previously experienced. Types of Medication Action— Allergic Reactions Mild Allergic Reaction Unpredictable reaction in which the patient becomes immunologically sensitized to a medication after taking the first dose. Need allergy bracelet if known history Symptomology Pruritis Urticaria Rhinitis Types of Medication ActionAllergic Reactions Anaphylactic Reaction Severe allergic reaction Requires immediate emergency intervention Symptomology Tachycardia Wheezing Edema of oropharynx/tongue Dyspnea Hypotension Types of Medication Action— Toxic Effects Can have lethal effects, depending on type of medication May be caused by: Overdose Prolonged intake of a drug Medication accumulates in the blood d/t impaired metabolism or excretion processes. Pharmacodynamics Medication Interactions When one medication modifies the action of another medication Interactions may be synergistic or antagonistic Can be therapeutic as well as nontherapeutic Pharmacodynamics Synergistic An effect resulting from two drugs—the effect of the two drugs combined is greater than the effects of the medications when given separately. Synergistic interaction can result in a nontherapeutic effect. Synergistic interaction can result in a therapeutic effect. Pharmocodynamics Antagonistic An effect resulting from two drugs—the effect of one drug reduces or abolishes the effect of the other drug Antagonistic interaction can result in a nontherapeutic effect. Antagonistic interaction can result in a therapeutic effect. Pharmacodynamics Compatibility Must be determined when mixing more than one drug in a syringe or IV tubing May need to be administered separately Medication Dose Responses Terms Associated with Medication Actions Onset Time it takes after you administer a drug to produce a response Peak Time it takes for a drug to reach its highest effective concentration Duration Time during which the drug is present in a concentration great enough to produce a response Initial Assessment Medication History Assess ALL medications Prescription Nonprescription Herbal supplements Length of time patient has been on medication Current dose schedule Medication Reconciliation Process recommended by TJC that exists for comparing current medications with those ordered for the patient. Rationale: Reduces the risk of transitionrelated med errors Initial Assessment Allergies/Intolerances All health care team members need to know patient’s medication and food allergies— All allergies and types of reactions should be noted on patient’s admission notes, H&P, and medication records Initial Assessment Medical History Obtain/review a medical history before giving medications Provides indications/contraindications for drug therapy May also discover medications patient may need Diet History Effective dosage schedule is planned around normal eating patterns and food preferences Teach patients to avoid foods that interact with medications Assessment Before Med Admin MAR Diet and Fluid Orders Lab Values Physical Assessment Assessment Before Med Admin Perceptual /Coordination Problems Physical or mental limitations can hinder patient’s ability to correctly take medications . Assess patient’s ability to prepare doses and administer medication May need to assess whether family or friends are willing and able to assist Patient’s Attitude About Medication Use Affects compliance of medication May reveal dependence or avoidance Observe behavior for evidence of medication dependence or avoidance Assess patient’s cultural beliefs Medication Errors Most common type of medical error 1.3 million patients harmed each year Costs=3.5 billion (Medical cost treating drugrelated injuries in hospitals each year 400,000 PREVENTABLE injuries in hospitals 530,000 PREVENTABLE injuries in OP clinics 800,000 PREVENTABLE injuries in LTC facilities Medication Errors Possible Causes Inaccurate prescribing Administering the wrong medication Administering extra doses Failing to administer a dose Giving the medication at the wrong time Wrong dose (too much/too little) Medication Errors When an error occurs, client safety and wellbeing are top priority If an error occurs Assess well-being of patient Notify MD or prescriber of the incident ASAP Report to manager/supervisor Complete incident report – usually filled out within 24 hours The Six Rights of Medication Administration Right Patient Right Medication Right Dose Right Route Right Time Right Documentation Right Patient Verify using two appropriate patient identifiers. (TJC) Right Medication Order required when giving any medication Always compare order in chart with MAR Meds from bottles or containers Compare the label of the medication container with the MAR (3) times Before removing the container from the drawer or shelf As you remove the medication ordered from the container Before returning it to storage Right Medication Unit-Dose Medications Check medication label and dosage when taking it out of the medication dispensing system Verify all medications at the patient’s bedside with the MAR. Administer ONLY the medications that YOU prepare. Right Dose Greater risk of error when preparing from stronger dose than needed or converting to another unit of measurement Right Route Medications can be given by more than one route Always consult with prescriber when route is not specified – DO NOT ASSUME If the prescribed route is not a recommended route, notify the prescriber immediately Right Time Know why medication is ordered for certain times of the day Prescriber often gives specific instructions about how to administer Right Time All routine ordered medications should be given within a 60-minute window of the prescribed time. Some meds may require your clinical judgment when determining the proper time for administration Right Documentation Document on MAR immediately after administration. Document any other needed information. NEVER document prior administering. If a dose is missed, document the reason. Right Documentation Record in nurses’ notes how the responds to the medication(positive or negative). If negative, inform MD. If refuses, investigate WHY. Document any refusal or withholding of medication Knowledge and Understanding Affects the patient’s ability to comply or adhere If patient understands reason of taking a drug, likelihood of compliance is enhanced. Teach medication purpose, proper administration techniques, and possible side effects If patient cannot afford medications, discuss financial resources. Learning Needs of the Patient Many patients do not understand their medications To assess learning needs, ask patients the purpose, expected side effects, correct administration techniques, etc. of their meds Noncompliance/Nonadherence The failure of a patient to take their medication as prescribed Why? Not uncommon, especially in the older adult spacing.ca Patient and Family Teaching Without good patient teaching, noncompliance is likely. It is essential to provide information about the purpose, action, and effects. Easy to read pamphlets Handouts Pt must also be aware of consequences if noncompliant. Patient and Family Teaching Daily Injections Must learn to prepare and administer injection correctly using aseptic technique Good to teach family/caregiver if patient becomes ill or physically unable Side Effects/Toxicity Family/caregiver also needs to be aware of symptoms of medication side effects or toxicity esp. if they are cognitive or behavioral in nature. Learning the basic guidelines for medication safety can ensure proper use and storage of medications in the home Special Considerations for Administering Medications Older Adults Physiological changes Behavioral changes Economic factors Evaluation Remember….evaluation is assessing a pt’s response to teaching as well as their response to medications It is an ongoing process … Requires YOU to know desired effect, side effects, nursing implications, etc. May use a variety of evaluative measures, e.g. rating scales, physiological measurements, observation of behavior, oral questioning, etc. End of Part I