Download SickleCellPPT(1)

Sickle Cell, The Sticky Cell:
7th Grade Life Science Module
Math and Science Partnership
Teacher’s Professional Development Workshop
McWane Science Center
September 19, 2013
Lauren C. Jackson Undergraduate TU
Dee Dee Canionero, M.S.
Dr. Chastity Bradford, PhD
Module Pre-Requisites
This module is designed for students with a
background knowledge of:
• The Central Dogma
• Chromosomes and Alleles
• The Circulatory System
Tuskegee University's
Department of Biology
• Introduce the Module Using the Five E Model
• Students should be able to…
Recognize Sickle Cell Anemia as an inherited genetic
disorder.
Understand the Punnett Square.
Relate major organs of circulatory system to their
functions.
 Blood Vessels Deliver Oxygen to the Body
Tuskegee University's
Department of Biology
The Five E Model
1.
2.
3.
4.
5.
Engage
Explain
Explore
Elaborate
Evaluate
Tuskegee University's
Department of Biology
Engage:
Pre-Test
Video
Tuskegee University's
Department of Biology
Living with Sickle Cell Anemia
This video—presented by the National Heart, Lung, and Blood Institute, part of
the National Institutes of Health—shows how Tiffany, a mother and student, has
coped with having sickle cell disease.
http://youtu.be/qe59ar-GZmg
Tuskegee University's
Department of Biology
Explain:
PPT Presentation that Highlights
Key Concepts
Tuskegee University's
Department of Biology
The Central Dogma
DNA  RNA  Protein
Tuskegee University's
Department of Biology
Determining Genotype and Traits:
Using The Punnett Square
Tuskegee University's
Department of Biology
DNA  RNA  ?
Protein: Building Blocks?
Amino Acids
Tuskegee University's
Department of Biology
Amino Acids
Tuskegee University's
Department of Biology
What is the Function
of Red Blood Cell ?
Carry Oxygen
Through Body
Tuskegee University's
Department of Biology
What do Red Blood Cells
Travel Through?
Blood Vessels
Tuskegee University's
Department of Biology
Circulatory System
• The overall function of the
• Circulatory System
circulatory system is to
• Organs:
transport blood throughout
Heart and Blood Vessels
the body.
– Arteries
– Veins
• Blood (Hemoglobin)
• Cells: Red Blood Cells
Tuskegee University's
Department of Biology
Protein
Shape
Function
Tuskegee University's
Department of Biology
The Punnett Shuffle
To the right (4x), To the left (4x)
Now switch (4x), Now move it down a square
(2x)
To the right (4x), To the left (4x)
That’s it (4x), Now that’s your Punnett Square
(2x)
Tuskegee University's
Department of Biology
Elaborate:
Review Worksheet
Tuskegee University's
Department of Biology
Sickle Cell Anemia:
A serious blood disorder, inherited from both parents, in which the
body makes sickle-shaped red blood cells instead of normal
shaped red blood cells.
Tuskegee University's
Department of Biology
Evaluate:
Post Test
Tuskegee University's
Department of Biology