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Anterior Knee Pain In Adolescents Johan Myburgh February 2012 Anterior knee pain • Introduction • Case study • Discussion – history – physical examination – investigations • Conditions • Growing skeleton Introduction • One of the most common musculoskeletal complaints - pediatric population • Differential diagnosis fairly extensive thorough history and physical examination • Special attention: – anatomic location of the pain – aggravating factors • Assessment of growth and development • Exclude hip and lumbar disorders (all patients) History • • • • • • • 15 year old male 2 month history anterior knee pain Progressively worse Aggravated by activity Noticed swelling below knee Karate – Provincial level Pain preventing exercise and tournament paticipation Clinical Examination • Observation: Swelling at the infrapatellar tendon attachment on the tibial tubercle. • Palpation: Tenderness to same area. • Flexibility: Hamstring tightness • Normal hip and lumbar spine examination Biomechanical evaluation • Excessive bilateral subtalar pronation - walking Special investigations: X-ray - fragmentation of the tibial tubercle with overlying soft tissue swelling. Summary (3 stage) 1. Clinical. Osgood-Schlatter disease – INTRINSIC FACTORS • biomechanical abnormality • immature skeleton – EXTRINSIC FACTORS • Kicking sport – FITT • Overtraining ( preparing for tournament) Summary (3 stage) 2. Personal. Karate is his passion - can’t imagine being not able to do it for possibly months. 3. Contextual Couch will not understand the chronic nature of his condition. Problem list • Active - Osgood-Schlatter disease • Passive - Excessive bilateral subtalar overpronation Management plan • Conservative 1. Regular icing of the area. 2. Modifying activities - No pain causing activities like jumping 3. Physiotherapy to correct biomechanical abnormalities and treat pain. • Progression: – physiotherapy and modified activity routine for 4 weeks – minor relapse of symptoms 2 weeks after resuming sport specific activities, but he started his treatment regime and the pain resolved. DISCUSSION Anterior Knee Pain HISTORY • Pain characteristics – location, character, onset, duration, change with activity or rest, aggravating and alleviating factors, and night pain. • Trauma – acute major trauma, repetitive minor trauma. • Mechanical symptoms – locking or extension block, instability • Inflammatory symptoms – morning stiffness, swelling • Bleeding disorders • Previous injury & treatments • Current level of functioning HISTORY • Overuse knee injuries - report sensation of knee instability – Pseudo-giving way due to a neuromuscular inhibition – Inhibition secondary to pain, muscle weakness and patellar instability. Physical Examination • Complete knee examination (above and below joints) – Examine - contralateral knee and the ipsilateral hip joint. • Biomechanical examination - predisposing factors. • Genetic predisposition includes excessive stiffness, loose-jointedness and poor muscle tone. • Knee joint swelling - suspicion of intra-articular pathology, synovitis Investigations • Laboratory testing – infection suspected - CBC, ESR, CRP – arthritis is diagnosed - anti-CCP, ANA, RF and HLAB27 for classification and treatment. • Imaging studies rarely used – Assist in diagnosis • Perthe’s and Slipped femoral capital epiphysis – X-rays and MRI most commonly used. Extensive differential diagnosis • Patellofemoral pain syndrome • Patellofemoral instability and patellar subluxation • Patellar tendinopathy (Jumper’s knee) • Osteochondroses • Fat pad irritation/impingement • Referred pain from the hip and lumbar spine • Osteochondritis Dissecans • • • • • • • • Synovial plica Quadriceps tendinopathy Bipartite patella Stress fracture of the patella Bursitis Inflammatory disorders Pain amplification syndromes Tumors Patellofemoral Pain Syndrome • most common cause of pediatric chronic anterior knee pain • etiology – malalignment of the patella relative to the femoral trochlea • result in articular cartilage damage – peripatellar synovitis secondary to mechanical overloading • chemical irritation of local nerve endings Patellofemoral Pain Syndrome • Risk factors – – – – malalignment of the lower limb larger Q-angles VMO weakness muscle inflexibilities like tight quadriceps, gastrocnemius, hamstrings, lateral retinaculum and IT band. • Classic Hx & Px • Quadriceps grinding test has a 96% sensitivity. • Management – modification of activity, flexibility and strengthening exercises, patellar tracking exercises, icing, NSAIDS, patellar taping and shoe orthotics. Other patellar pathology • Patellofemoral instability and patellar subluxation – Clinically looks like patellofemoral pain syndrome - but lateral dislocation may be elicited with palpation • Patellar tendinopathy (Jumper’s knee) – – – – common cause of infrapatellar knee pain associated with osteochondroses and PFP Rx activity modification and biomechanical rehabilitation Progressive eccentric strengthening is essential. OSTEOCHONDROSES • adolescents during growth spurt • present with localized pain with activities , localized tenderness and swelling • X-rays only if infection or bony tumors are suspected. • Self-limiting disorders - managed conservatively • Conservative management includes activity modification, biomechanical rehabilitation, icing, NSAIDS, muscle strengthening and muscle flexibility exercises. • can last ≤ 24 months until skeleton matures. symptoms persist past skeletal maturity surgery indicated to excise the separated tibial tuberosity fragment. KNEE OSTEOCHONDROSES Patella Sinding-Larsen-Johansson syndrome (SLJD) Osgood-Schlatter Tibial Tuberosity Tibia • More common • inferior attachment of patellar tendon , epiphysis of the tibial tubercle superior attachment of patellar tendon OSTEOCHONDROSES Osgood-Schlatter (OSD) Sinding-Larsen-Johansson Syndrome (SLJD) Osgood-Schlatter Disease • What’s new/controversial ? Journal Pediatrics July 2011 Hyperosmolar Dextrose Injection for Recalcitrant Osgood-Schlatter Disease – injection of the patellar tendon enthesis/tibial apophysis with 12.5% dextrose (monthly x 3) – better 3,6,12 month outcome in pain score (NPPS— Nirschl Pain Phase Scale) than usual care – Release several growth factors and neuropeptides Conditions • Fat pad irritation/impingement – Infrapatellar fat pad is a richly innervated area – Impingement occurs between the patella and femoral condyle – Caused by direct trauma or a hyperextension injury • Patellar tendinopathy, PFP and synovitis can cause chronic irritation. • Referred pain from the hip and lumbar spine – Perthe’s disease or slipped capital femoral epiphysis may present with knee pain. Conditions • Osteochondritis Dissecans – Idiopathic bone necrosis – Acute, hemarthrosis and loose body ( locked knee) – Most common lateral aspect of the medial femoral condyle • Synovial plica – – – – Local synovitis caused by microtrauma synovium trapped between the patella and the femoral condyle. medial knee pain a thickened band when pressed against the condyle • Quadriceps tendinopathy – Uncommon Conditions • Bipartite patella – superolateral patella may show an accessory ossification centre ( pain and swelling) • Stress fracture of the patella – – – – uncommon condition jumping athletes intense localized pain and swelling X-ray chronic stress reaction (bone scan) • Bursitis – Prepatellar bursa most commonly affected – Infrapatellar bursitis mimic tendinopathy • Aspirate bursa if septic arthritis is suspected Conditions • Inflammatory disorders – Juvenile inflammatory arthritis • • • • morning stiffness and gradual resolution of the pain with activity monoarthritis screen for asymptomatic uveitis confused with OSD (morning symptoms differentiate) • Pain amplification syndromes – Reflex sympathetic dystrophy, reflex neurovascular dystrophy and complex regional pain syndrome • pain out of proportion with the amount of trauma • unwillingness to weight bear and allodynia (pain from a nonpainful stimulus) • signs of autonomic dysfunction • special investigations are not helpful. Conditions • Tumors – rare cause on anterior knee pain – local osteosarcoma, leukemia and metastasis from neuroblastoma Growing skeleton • Osteochondroses Type Condition Perthe’s disease spine •Articular Referred pain from the hip and lumbar Non-articular Physeal Site Femoral head Osteochondritis dissecans Medial femoral condyle, capitellum, talar dome Osgood-Schlatter Tibial tubercle Sinding-Larsen-Johansson Inferior pole patella Sever’s lesion Calcaneus Sheuermann’s lesion Thoracic spine Blount’s lesion Proximal tibia • Referred pain form hip and lumber spine Conclusion • Anterior knee pain - common in the pediatric population • Thorough history and physical examination necessary, often enough to make an accurate diagnosis. • Patellofemoral joint and the extensor mechanism of the knee - most common areas affected • Conditions unique to the growing skeleton like hip diseases (Perthe’s and SCFE) and osteochondroses • Systemic diseases (inflammatory disease and malignancies) should be in differential diagnosis References • Cassas KJ. Childhood and adolescent sports-related overuse injuries. Am Fam Physician. Mar 2006; 73(6): 1014-22. • Patel DR. Musculoskeletal injuries in sports. Prim Care. Jun 2006; 33(2): 545-79. • Mercier LR. Osgood-Schlatter disease. Ferri’s Clinical Advisor: Instant Diagnosis and Treatment. 9th ed. St. Louis, Mo: Mosby; 2009:593 • D Caine, J DiFiori, and N Maffulli. Physeal injuries in children's and youth sports: reasons for concern?, Br J Sports Med. 2006 September; 40(9): 749–760 • Houghton KM. Review for the generalist: evaluation of anterior knee pain. Pediatric Rheumatology 2007, 5:8 • Gastón Andrés Topol, MD, Leandro ArielPodesta, MD, Kenneth Dean Reeves, MD, Marcelo Francisco Raya, PT, Bradley Dean Fullerton, MD,and Hung-wen Yeh, PhD: Journal Pediatrics July 2011 • Brukner and Khan Revised 3rd edition Thank you