Download M.Sc.Chemistry (CBCS) Program M1CHE01

M.Sc.Chemistry (CBCS) Program
M1CHE01-CT01 Inorganic Chemistry
S.No.
1
Lecture no.
1
Prof. A.K. Goswami
Unit
1
2
3
4
5
6
7
8
9
10-11
2
12
13
14
2
15
16
17
3
18
19
20
21
22
23
24
3
25
4
26
27
28
29
30
31
4
5
32
33
34
5
Metals viz; Transition metals suitable for complexation,
Fundamental requirement of any acceptor to go for
complexation, primary and secondary valence
Inner-d and outer-d complexes, ligand an electron pair donor,
denticity, classification of ligands HSAB Concept, Concept
behind electron pair donor nature of any ligand
VSEPRT- The backbone of complexation, nature of metalligand bonding, property of metal complexes
Help of CFT in explanation the properties of metal complexes
CFT vs LFT
LFT contents
Shortcomings of CFT
MOT vs LFT
MOT and Complexes
MOT/CFT/LFT Comparison
Stepwise and overall formation constants
Their reaction
Factors affecting the stability of metal complexes with
presence of nature of metal ion and ligand
Chelate effect and its thermodynamic origin
Determination of binary formation constants by pH-metry
Determination of binary formation constants by
spectrophotometry
Energy profile of a reaction, reactivity of metal complexes
Inert and labile complexes
Application of VBT and CFT
Kinetics of octahedral substitution
acid hydrolysis, Factors affecting acid hydrolysis
Base hydrolysis, conjugate base mechanism
Direct and indirect evidences in favour of reaction rate
mechanism
Anation reactions, reactions without metal ligand bond
cleavage
Substitution reactions in square planar complexes
Trans effect
Mechanism of substitution reaction, redox reaction
Electron transfer reactions
Cross reactions and inner sphere type reactions
Marcus-Hush theory
Spectroscopic states
Correlation, Orgel diagram for transition metal complexes
Tanabe-Sugano diagram for transition metal complexes
35
36
37
38
39
40
Calculations of Dq, B and a Parameters
Charge transfer spectra
Spectroscopic of assignment of absolute configuration in
optically active metal chelates
Anomalous magnetic moments
Magnetic exchange coupling
Spin Cross over
REFERENCES
1. Advanced Inorganic Chemistry, F.A.Cotton and Wilkinson, John Wiley
2. Inorganic Chemistry, J.E.Huhey, Harpes & Row
3. Chemistry of the Elements, N.N. Greenwood and A. Earnshow, Pergamon.
4. Inorganic Electronic Spectroscopy, ABP Lever, Elseview
5. Magnetochemistry, R.L. Carlin, Springer Verlag
6. Coordination chemistry, D Banerjea
7. Inorganic and Solid-State Chemistry, Glen E. Rodgers
8. Inorganic chemistry, Gary Wulfsberg
9. Transition metal chemistry, Basalo and Johnsons
SEMESTER- I
PAPER: M1CHE-CT02: Organic Chemistry
[NOTE: At the beginning of the semester, students must be provided : Detailed lecture schedule
of topics to be covered in each lecture , tutorial topics, clearly defining chapters /sections of
reference books followed ,link to web resources etc. Examiners are expected to take into
consideration the lecture schedule while setting the question papers to ensure questions are set
within scope of the syallabus]
External: 80 Marks
Internal: 20 Marks
Classroom Lectures : 40
Additional Contact hours: 10 (seminars, quiz, assignments, group discussion etc.)
Lecture
No.
1.
2.
3.
4.
5.
6.
7
8
9
10
11
12
13
14
15
16
17
18
Topic
Text/ Reference
UNIT 1 Nature of bonding in organic molecules
Delocalized chemical bonding- conjugation
Jerry march
Cross conjugation, Bonding in fullerenes
Jerry march
Aromaticity in benzenoid and non-benzenoid compounds
Alternant and non alternant hydrocarbons, Huckel’s rule
,energy level of π molecular orbitals
Annulenes , ferrocenes and helicenes
Anti aromaticity ,homo- aromaticity ,PMO approach
Jerry march
Jerry march
Jerry march
Jerrymarch,
Mukherjee & Singh
Jerry march
UNIT 2 Reaction mechanism, structure and reactivity
A review of types of mechanism & RXS, Methods of
determining mechanism
Kinetic and thermodynamic control, Hammond’s postulate, Jerry march, Peter
Curtin-Hammett principle
Sykes
Potential energy diagrams, transition states and intermediates
Jerrymarch,
Mukherjee & Singh
Isotope effect, effect of structure on reactivity-resonance and Jerrymarch,
field effect
Mukherjee & Singh
Steric effect , steric inhibition to resonance, substituent and Jerry march, Peter
reaction constants ,Taft equation
Sykes
Jerry march , P.S.
UNIT 3 Aliphatic reaction Mechanism
i)Nucleophilic substitution- SN2 , SN1
Kalsi
Mixed SN2 &SN1 , SNi & SET mechanism
Jerry march, P.S. Kalsi
Classical & non classical carbocation , phenonium ion, nor Jerry march, P.S. Kalsi
bornyl system, common carbocation
Neighbouring group participation, rearrangements
Jerry march, P.S. Kalsi
Nucleophilic substitution at allylic, trigonal & vinylic carbon Jerry march, P.S. Kalsi
Reactivity effects of substrate structure, attacking Jerry march, P.S. Kalsi
nucleophille ,leaving group and reaction medium
Ambient nucleophile, Regioselectivity
Jerry march, P.S. Kalsi
19
ii)Electrophilic Substitution- SE2 & SE1 mechanism,
Electrophillic substitution accompanied by =bond shift.
20
Effect of substrates, leaving group & the solvent polarity on Jerry march, P.S. Kalsi
reactivity.
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
UNIT 4 Aromatic reaction Mechanism
i)
Electrophilic
SubstitutionArenium
ion
mechanism,orientation and reactivity ,energy profile diagrams
the ortho/para ratio , ipso attack,orientation in other ring
systems,
Diazonium coupling, Vilsmeir –Haak reaction, BischlerNapieralske recation, Pechmann Reaction
ii)Nucleophilic Substitution- The Sn Ar ,SN1 ,benzyne and
SRN1 mechanism. -.
Reactivity effect of substrate structure ,leaving group and
attacking nucleophile
The Von Richter,Sommetet -hauser and Smiles
rearrangements
iii) Free radical reaction- Types of free radical reactions,
free radical substitution mechanism, neighbouring group
assistance
Reactivity for aliphatic and aromatic substrate at a
bridgehead, reactivity in the attacking radicals, the effects of
solvents on reactivity
Allylic halogenations(NBS), oxidation of aldehydes to
carboxylic acids , autooxidation ,
Coupling of alkynes and arylation of aromatic compounds by
diazonium salts, Sandmeyer
reaction, free radical
rearrangement, Hunsdiecker reaction
UNIT 5 Addition Reaction
i)C-C Multiple bonds – Mechanistic and Streochemical
aspects
of addition reaction involving electrophiles,
nucleophiles & free radicles,
Regio & chemoselectivity, Orientation & reactivity , addition
to cyclopropane ring.
Hydrogenation of double bond, triple bond & aromatic
ring,hydroboration, Michael reaction
ii)Carbon Hetero multiple bonds- Mechanism of metal
hydride, reduction of saturated & unsaturated carbonyl
compounds.
Addition of G.R., organozinc &organo Li reagents to
carbonyl & unsaturated >C=O compounds
Wittig reaction ,Mechanism of condensation rxs involving
enolates- Aldol , knoevengel reaction
Mannich , Benzoin, Perkin & Stobbe reaction
iii)Elimination reaction- The E2, E1,ElcB and E2c
mechanism s 38 and their spectrum
Orientatin of the double bond , reactivity- effect of substrate
structures, attacking base, the leaving group and the medium
Stereochemistry, elimination v/s substitutions, pyrolytic
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
Jerry march, P.S. Kalsi
eliminations.
TEXTS/ References:
1)
2)
3)
4)
5)
Advanced organic chemistry –Reactions,Mechanism and Structure, Jerry March.
Stereochemistry of organic compounds, P.S.Kalsi, New age International.
Organic Reaction and their Mechanisms, P.S.Kalsi, New age International.
Reaction Mechanism in organic Chemistry, S.M. Mukherjii and S.P. Singh.
Structure and Mechanism in organic Chemistry, Peter Sykes, Longman.
SEMESTER-I
PAPER: M1CHE03-CT03: Physical Chemistry
[NOTE: At the beginning of the semester, students must be provided: Detailed lecture schedule
Topics to be covered in each lecture, tutorial topics, clearly defining chapters /sections of
reference books followed, link to web resources etc. Examiners are expected to take into
consideration the lecture schedule while setting the question papers to ensure questions are set
within scope of the syllabus]
External : 80 Marks
Internal : 20 Marks
Class Room Lectures : 40, Tutorials : 10 Hrs, Additional Contact hours: 10 (seminars, quiz,
assignment, group discussion etc.)
LECTURE
TOPIC
NO.
1.
Methods of determining rate laws and
mechanism
2.
Collision theory of reaction rates
3.
Activated complex theory, steric factor
4.
Arrhenius equation
and thermodynamic parameters
5.
Ionic reactions, kinetic salt effects
6.
Steady state kinetics
7.
Kinetic and thermodynamic control of
reactions,
8.
Fast reactions
9.
Catalysis, homogeneous catalysis
10.
Kinetics of enzyme reactions
11.
Chain reactions
12.
Photochemical reactions( HydrogenBromine)
13.
Photochemical reactions( HydrogenChlorine)
14.
Oscillatory reactions
15.
Belousov-Zhabotinsky reaction
16.
Macromolecules: Definition, types of
polymers
17.
Electrically conducting, fire resistant
and liquid crystal polymers
18.
Kinetics of polymerization, Mechanism of
Polymerization
19.
Molecular mass Number and mass
average molecular mass
20.
Molecular mass determination Methods:
Osmometry, Viscometry, Diffusion
21.
Molecular mass determination Methods:
Light scattering methods, GPC ,
BOOKS RECOMMENDED
1. Chemical Kinetics, K.J.
Laidler, Mcgraw-Hill
2. Kinetics and Mechanism of
Chemical Transformations,
J.
Rajaraman
and
J.
Kuriacose, McMillan.
3. Atkins, P. W. & Paula, J. de
Atkin's Physical Chemistry
8th Ed., Oxford University
Press(2006).
4. Engel, T. & Reid, P. Physical
Chemistry BenjaminCummings (2005).
1. Physical chemistry of
Macromolecules, vol
164, Wiley
2. Advanced physical
chemistry, Gurdeep Raj,
Goel Publishing house,
Meerut
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
Sedimentation.
Quantum chemistry: The Schrodinger
equation
postulates of quantum
mechanics
Solution of schrodinger equation for
particle in 1-D and 3-D box
Solution of schrodinger equation for the
harmonic oscillator
First order time-independent perturbation
theory for non- degenerate states
Variation theorem and variational
methods
variational method for particle in a box
with a finite barrier
Variational method anharmonic oscillator
Approximate functions for particle in a
box
Approximate functions for hydrogen atom
Angular momentum: Ordinary angular
momentum, generalized angular
momentum
Eigen functions and Eigen values of
angular momentum
Operators, Algebra of operators
Ladder operators, addition of angular
momenta,
Spin, antisymmetry and Pauli’s exclusion
principle.
Electronic configuration, RussellSaunder’s terms and
coupling schemes
L-S and J-J Coupling schemes
Huckel theory of conjugated systems
application to ethylene and butadiene
Bond order and Charge density
calculations to ethylene and butadiene
1. Lowe, J. P. & Peterson,
K. Quantum Chemistry
Academic Press (2005).
2. McQuarrie, D. A.
Quantum Chemistry Viva
Books Pvt. Ltd.: New
Delhi (2003).
3. Mortimer, R. G.
Mathematics for Physical
Chemistry 2nd Ed.
Elsevier (2005).
4. Pilar, F. L. Elementary
Quantum Chemistry 2nd
Ed., Dover Publication
Inc.: N.Y. (2001).
5. Levine, I. L Quantum
Chemistry 5th Ed.,
Prentice-Hall Inc.: New
Jersey (2000).
SEMESTER- I
PAPER: M1CHE04-CT04: Group Theory and Spectroscopy
[NOTE: At the beginning of the semester, students must be provided: Detailed lecture schedule
Topics to be covered in each lecture, tutorial topics, clearly defining chapters /sections of
reference books followed, link to web resources etc. Examiners are expected to take into
consideration the lecture schedule while setting the question papers to ensure questions are set
within scope of the syllabus]
External : 80 Marks
Internal : 20 Marks
Class Room Lectures : 40, Tutorials : 10 Hrs, Additional Contact hours: 10 (seminars, quiz,
assignment, group discussion etc.)
Lecture
Topic
Text / Reference
No.
1
F. A. Cotton.
Symmetry and Group theory in Chemistry:
Symmetry elements and symmetry operation,
2,3
Point symmetry group, Schonfilies symbols.
F. A. Cotton.
4, 5
Definition of group, subgroup. Conjugacy relation F. A. Cotton.
and classes.
6,7
Representation
of
groups
by
matrices F. A. Cotton.
(representation for the Cηh, Cηv, etc. groups to be
worked
out
explicitly).
Characters
of
a
representations.
8, 9
Derivation of character table for C2ν and C3ν point F. A. Cotton.
group, symmetry aspects of molecular vibrations
of H2O molecule.
10,11
The great orthogonality theorem (without proof)
and its importance. Character tables and their use;
F. A. Cotton.
spectroscopy.
12
Unifying Principles: Electromagnetic radiations, G. Aruldhas
Interaction of electromagnetic radiation with
matter. Uncertanity relation and natural line width.
13
Factors
affecting
natural
line
width,
Born G. Aruldhas
oppenheimer approximation.
14, 15
Photoelectron
spectroscopy:
Franck
Condon C N. Banwell and Elaine M.
principle, types of electron spectroscopy, ESCA Mc. Cash
theory,
instrumentation
and
applications,
Auger
emission spectroscopy-Basic idea.
16
Rotational
spectroscopy:
classification
of
molecules, rigid
rotator, effect
of isotopic
substitution
the
frequencies,
on
transition
1. C N. Banwell and
Elaine M. Mc. Cash
2. G. Aruldhas
intensities,
17
Non-rigid rotor, stark effect, Nuclear and electron
spin interaction and effect of external field,
1. C N. Banwell and
Elaine M. Mc. Cash
applications.
18
Vibrational Spectroscopy
Review of linear harmonic oscillator, Vibrational
C N. Banwell and Elaine M.
Mc. Cash
energies of diatomic molecules, Zero Point
energy, force constant and bond strength,
19
Anharmonicity, Morse Potential energy diagram
20
Vibration-rotation spectroscopy, P.Q.R. branches,
21
Breakdown
of
oppenheimer
selection rules, finger print region,
22
1. C N. Banwell and
Elaine M. Mc. Cash
2. G. Aruldhas
approximation, C N. Banwell and Elaine M.
Mc. Cash
Group frequencies and intensities, overtones, hot
bands, combination bands and Fermi resonance.
23
Raman spectroscopy: Classical and quantum
theories
of
raman
effect,
C N. Banwell and Elaine M.
Mc. Cash
Stokes
and anti-
1. C N. Banwell and
Elaine M. Mc. Cash
2. G. Aruldhas
1. C N. Banwell and
Elaine M. Mc. Cash
2. G. Aruldhas
Stokes lines,
24, 25
Pure rotational, vibrational, rotational- vibrational
Raman spectra, Mutual exclusion principle.
26
IR Spectroscopy - (Characterization of functional
groups) : Normal modes of vibration
27, 28
1. C N. Banwell and
Elaine M. Mc. Cash
2. G. Aruldhas
1. William Kemp
2. Jagmohan
Characteristic vibrational frequencies of alkanes,
alkenes, alkynes, aromatic compounds, alcohols,
1. William Kemp
2. Jagmohan
ethers, phenols and amines.
29, 30
Detailed study of vibrational frequencies of
carbonyl compounds (ketones, aldehydes, esters,
amides, acids, anhydrides, lactones, lactams and
conjugated carbonyl compounds)
1. William Kemp
2. Jagmohan
31, 32
Factors affecting the band positions, brief idea
of FT-IR.
33, 34
Ultra-violet and visible spectroscopy:
Various electronic transitions, Beer-lambert law
35, 36
Effect of solvent on electronic transitions, UV
spectra of carbonyl compounds, unsaturated
1. William Kemp
2. Jagmohan
1. William Kemp
2. Jagmohan
1. William Kemp
2. Jagmohan
carbonyl compounds, dienes, conjugated polyenes,
37, 38
Woodward-Feiser rules for conjugated dienes and
carbonyl compounds.
39, 40
UV spectra of benzene and its derivatives,
applications of UV spectroscopy
1. William Kemp
2. Jagmohan
1. William Kemp
2. Jagmohan
1. Chemical Applications of Group Theory, F. A. Cotton.
2. Molecular Structure and Spectroscopy, G. Aruldhas, PHI.
3. Modern Spectroscopy, J.M. Hollas, John Wiley.
4. Symmetry and Group theory: Some chemical applications, Ramashankar and Suresh
Ameta, Himanshu Publications, Udaipur, Delhi.
5.
Introduction to Molecular Spectroscopy, G.M. Barrow, McGraw Hill
6. Colin N. Banwell and Elaine M. McCash, Tata McGraw Hill.
7. Organic Spectroscopy, William Kemp, ELBS.
8. Organic Spectroscopy Principles & Applications, Jagmohan, Published by Narosa
Publishing House.
9. Basic Principles of Spectroscopy, R. Chang, McGraw Hill.
10. Theory and Applications of UV Spectroscopy, H.H. Jaffe and M. Orchin, IBH- Oxford.