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The Human Body - Introduction Homework: Review Body Atlas Pg. 223-232 Study slides and notes for quiz next week Body Systems Structural Organization • Atoms – molecules – cell organelles – cells – tissues – organs – systems – person Cells • The smallest living unit in us • 100 trillion in body • 10x bacteria in and on us • Need to reproduce • Need to perform their work • Need to live and die “healthy” Maintaining Life – External Boundaries • Interdependence of all systems and their organs, tissues, and cells • Boundaries from environment • Intensely separate but highly interactive (selective) with outside environment • Keeps out physical and chemical factors, microbes, dryness, and radiation. Regulates temperature • Integumentary System (skin, hair, nails) • The external boundaries on the inside – membranes and immune system Maintaining Life – Internal Boundaries • Internal boundaries also exist throughout the body to separate systems, organs, tissues, cells yet allow them to interact with each • Internal Boundaries created by • • • • Body cavities Organ membranes, tissue membranes, and cell membranes Cell compartments Cytoskeletons Internal Boundaries in the body and cell Maintaining Life - Movement • Macro movement • Muscular System • Skeletal System • Internal System movement • Blood, Urine, Respiration, Digestion, smooth muscle (heart, stomach, etc) • Micro movement – cellular movements • Cell generation • Cell machinery • Immune cells Maintaining Life – Other Factors • Digestion • breakdown of food, also used at cellular level (catabolism) • Metabolism • All chemical reactions that occur in the body – anabolism, catabolism, power (ATP synthesis) • Excretion – waste disposal through respiratory, digestive, and urinary systems • Growth • Reproduction Maintaining Life - Responsiveness • Stimuli → Response (effect) • Response occurs at system, tissue, cell, etc • Macro • e.g. Injure hand – reflex • e.g. Cut – vessels contract • Homeostasis • e.g. Temperature, Blood Pressure, CO2 Homeostasis - definitions 1. The body’s ability to maintain relatively stable internal conditions even though the outside world changes continuously 2. A dynamic state of equilibrium or balance in which internal conditions vary, but always within relatively narrow limits 3. When the body’s needs are adequately met and it is functioning smoothly 4. Sickness is a lack of homeostasis Homeostatic Precision • Monitoring of “normal” • Continually adjusts to normal by helping or hindering body processes • Communication of this occurs through the • Nervous System • Endocrine System Examples Targets (variables) for Homeostasis • Hundreds of variables • • • • • Body Temperature Blood Pressure (BP), Heart Rate Breathing, Blood Oxygen Blood Volume Blood Chemistry (e.g. Sodium levels, acid-base) Homeostatic Components • Stimulus – outside influence • Variable– the factor or event being regulated • Receptor • Monitors environment and responds to stimuli (changes) • Sends messages through afferent pathway • Control Center • • • • Receives messages from receptor Compares to set point (normal) Determines correct response Messages effector through efferent pathway • Effector • Body components that respond to Control Center • Feedback (back and forth) through whole process Homeostasis Response to cold Stimulus: Decreased room temp Variable: Core body temperature Receptor: Hypothalamus Control: Brain Effectors? Response? Negative Feedback Mechanisms • Most responses are negative feedback (to push against the stimuli) • Reduce or negate effect of stimuli • Variable (target) goes in opposite direction Positive Feedback Mechanisms • Infrequent events not requiring continual adjustment are under positive feedback • Contractions during labor • Blood Clotting • • • • Amplify or cascade effect Allows effect of stimuli to increase Variable deviates farther from origin Negative feedback systems in place to turn off positive mechanisms Analogies to the Body of Christ – His Church • Separate systems, organs, tissues, and cells • All separate but meant to be highly integrative • Love for one another is the integration – active love • Homeostasis • • • • • • Jesus is the control center We are or the church is the variable Effects His children and churches as necessary to get to the “set point” The life and character of Jesus is our “set point” that God wants in us Our character – negative feedback loop His love to others through us – positive feedback loop