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Bloodborne Pathogens/Infection Control Tuberculosis Awareness CDM 3rd years and Post-docs June 29th 2016 Biological Safety Officer: Aderemi Dosunmu Ph.D.– [email protected] Manager, Biological Safety Program: Christopher Aston Ph.D. [email protected] Biosafety www.ehs.columbia.edu Why is Biosafety Important in Dentistry? You will come in contact with blood, oral and respiratory secretions Contaminated equipment can occur Both patients and dental health care personnel (DHCP) can be exposed to pathogens Proper procedures can prevent transmission of infections between patients and DHCP Biosafety www.ehs.columbia.edu Agenda Infection Control Bloodborne Pathogens Occupational Exposure Sharps Safety Regulated Medical Waste Environmental Surfaces and Spill Response Personal Protective Equipment TB Precautions Biosafety www.ehs.columbia.edu Chain of Infection Pathogen Susceptible Host Vaccination Entry Disinfection Source Mode Safe sharps handling PPE Biosafety www.ehs.columbia.edu Infection Control SOPs were created for the protection of the patient and the and DHCP Attend training Wear PPE Perform safe work practices Report incidents “Institutional safety committees should implement and maintain surveillance programs to identify & monitor acute illness. Healthcare providers should routinely inquire about occupational exposures when evaluating patients.” “Any microorganism in the wrong place, in the wrong person, is capable of causing illness or death”. Biosafety www.ehs.columbia.edu Worse Case Scenario First documented report of patient-topatient transmission of hepatitis C virus associated with a dental setting in the United States. Improper sterilization techniques. Using single vials of medications on multiple patients. No written infection control protocol. Biosafety www.ehs.columbia.edu Standard Precautions Apply to all patients regardless of actual or perceived risk factors; treat all blood or Otherwise Potentially Infectious Material (OPIM) as if infectious. Body fluids, secretions e.g., saliva and excretions (except sweat), whether or not they contain blood Non-intact (broken) skin Mucous membranes Biosafety www.ehs.columbia.edu Elements of Standard Precautions Hand washing Use of gloves, masks, eye protection, and gowns Disinfection of patient care equipment Disinfection of environmental surfaces. Alternatively, cover what you can Injury prevention Biosafety www.ehs.columbia.edu Bloodborne Pathogens HIV HBV • Lifetime infection • No vaccine, no cure • Jaundice • Symptoms and • Risk factors: Sharps and transmission risk needlesticks factors similar to • Chronic infection develops HBV ~5% of the time, • Untreated-chronic increasing risk for infection and #1 cirrhosis, liver cancer reason for liver • Environmental persistence transplant on surfaces • No Vaccine • Vaccine Available HCV Biosafety www.ehs.columbia.edu HBV Vaccine Vaccine Efficacy >90% Currently part of childhood schedule OSHA requires employers to offer vaccination to employees with potential occupational exposure Biosafety www.ehs.columbia.edu Bloodborne Pathogens Transmission Probabilities after Needlestick MATCH THE VIRUS WITH THE RISK Source Risk Up to 30 % HIV 1.8% (0%-7% range) HCV 0.3% (0.2%-0.5% range) HBV~0% when vaccinated Which one of these probabilities can be reduced to zero? Biosafety www.ehs.columbia.edu Occupational Bloodborne Pathogen Exposure Evaluations at Columbia Student Health Services Historically, what percentage of occupational exposures reported to Student Health Services consisted of Dental Students? A. 0 - 5% B. 5 - 44% C. 45 - 66% D. 67-100% Biosafety www.ehs.columbia.edu Occupational Bloodborne Pathogen Exposure Evaluations at Columbia Student Health Services Year Dental School (% of total evaluations) 2004-2005 66% 2007-2008 44% 2008-2009 62% 2009-2010 53% Historically, about 2/3 of all occupational exposures reported to Student Health Services consisted of Dental Students. Lowest exposure year was 2007-2008. Students that sustain an occupational exposure from a known HIV-positive patient seen at SHS, in excess of 75% of those exposure occur in dental students. Source: Thomas Mele, MD Instructor in Clinical Medicine Biosafety www.ehs.columbia.edu Biosafety www.ehs.columbia.edu Occupational Exposure Largest Risk? Needlestick: ‘stick’ from any contaminated item; mucous membrane, non-intact skin exposure Clean with Betadine and antimicrobial soap Rinse eyes/mucous membranes 10 minutes Inform Supervisor All patients, students or faculty/staff injured in the clinical facility should file an "Accident Report General Liability". Forms available in the Clinic Administration Office Biosafety www.ehs.columbia.edu HIV-Post Exposure Evaluation First response, seek medical attention Prophylactic Medication must be given ASAP “within a few hours” – Protease Inhibitors that reduce viral load and inhibit replication at different step vs. AZT. Regimen based on hazard of source material Follow-up testing * For HBV and HCV, post-exposure anti-viral medication may be given Biosafety www.ehs.columbia.edu Agenda Infection Control Bloodborne Pathogens Occupational Exposure Sharps Safety Regulated Medical Waste Environmental Surfaces and Spill Response Personal Protective Equipment TB Precautions Biosafety www.ehs.columbia.edu Sharps Safety Biosafety www.ehs.columbia.edu When Do Needle-stick Injuries Occur? What’s your Guess? 2% Before use 38% During use: passing equipment, collision w/ worker 42% After use/before disposal: activating safety feature, recapping 18% During and after disposal: improper disposal Biosafety www.ehs.columbia.edu Substitution – ENGINEERED SHARPS ‘Safe Needles’ mandatory OSHA requirement to use safest ‘sharp’ possible, engineered-in safety features AVOID breaking, bending, or recapping needles. Biosafety www.ehs.columbia.edu Sharps Safety – Scoop Method Biosafety www.ehs.columbia.edu Regulated Medical Waste Management Properly labeled containment to prevent injuries and leakage • Red bag waste • Sharps waste Medical wastes are “treated” in accordance with state and local EPA regulations Processes for regulated waste include autoclaving and incineration Biosafety www.ehs.columbia.edu What Goes in the Sharps Container? Needles Syringes Etchants Sealants Composite Glass Scalpel blades Orthodontic wires Endodontic files Burs Irrigation syringes --Anything that would rip a red bag --Unused sterile sharps --Empty carpules Biosafety www.ehs.columbia.edu What Goes in Red Bags? or Biosafety www.ehs.columbia.edu Red Bags Are Not Storage Units Red bag bins are not a place to store: • Coats • Bags • Dental trays Please use it for its intended purpose: an unobstructed method to discard RMW Biosafety www.ehs.columbia.edu What Goes Where No food or drink permitted in the clinic Iris’ shop Biosafety www.ehs.columbia.edu Extracted Teeth Teeth are Regulated Medical Waste • *Extracted teeth must be placed in the designated, pre-labeled “Extracted Teeth Containing Amalgam ” regardless of whether the teeth contain amalgam or not. • Disinfect before disposal; containers • have a solution of 10% bleach Do not incinerate extracted teeth Teeth can be given back to patient *If it is determined that histologic evaluation is not required Biosafety www.ehs.columbia.edu Environmental Surfaces-2 Types Clinical contact surfaces High potential for direct contamination from spray or spatter or by contact with DHCP’s gloved hand Housekeeping surfaces Do not come into contact with patients or devices Limited risk of disease transmission Biosafety www.ehs.columbia.edu Clinical Contact Surfaces High potential for direct contamination from spray or spatter or by contact with DHCP’s gloved hand Biosafety www.ehs.columbia.edu Housekeeping Surfaces Generally do not come into contact with patients or devices Limited risk of disease transmission Biosafety www.ehs.columbia.edu Spills CODM staff / students can clean small blood spills on clinical contact surfaces Cleaning materials and PPE are available in the clinics • Gloves, paper towels, bleach When to ask for help? • Spills on housekeeping surfaces, large spills, aspiration system failure Biosafety www.ehs.columbia.edu Spills Policy Biosafety www.ehs.columbia.edu Personal Protective Equipment A major component of Standard Precautions Protects the skin and mucous membranes from exposure to infectious materials in spray or spatter Should be removed when leaving treatment areas Biosafety www.ehs.columbia.edu Personal Protective Equipment Disposable gowns should also be changed daily or when they become visibly soiled. • Dispose in normal waste (non-red bag) Gowns are either front or rearopening; NOT reversible. Splatter, splash or aerosol-producing procedures = Surgical masks and protective eyewear worn at all times during procedures, whether active or observing Biosafety www.ehs.columbia.edu Gloves Minimize the two-way transmission of microorganisms between patients and providers Reduce contamination of the hands of health care personnel by microbial flora that can be transmitted from one patient to another Not a substitute for hand washing or sanitizing! Biosafety www.ehs.columbia.edu Hand Hygiene When removing gloves, no glove is 100% effective Change ASAP after visible contamination ‘Purell’ or soap and water? Technique is important or ? Biosafety www.ehs.columbia.edu Special Hand Hygiene Considerations Use hand lotions to prevent skin dryness Be careful of hand care products and gloves (e.g., mineral oils and petroleum bases may cause early glove failure) Keep fingernails short Avoid artificial nails Avoid hand jewelry that may tear gloves Biosafety www.ehs.columbia.edu Agenda Infection Control Bloodborne Pathogens Occupational Exposure Sharps Safety Regulated Medical Waste Environmental Surfaces and Spill Response Personal Protective Equipment TB Precautions Biosafety www.ehs.columbia.edu Risk of Transmission of Mycobacterium tuberculosis (TB) M. tuberculosis is spread by droplet nuclei Immune system usually prevents spread Latent infection: Bacteria can remain alive in the lungs for many years (not transmissible) Biosafety www.ehs.columbia.edu Risk of TB Transmission in Dentistry Risk in dental settings is low Only one documented case of transmission Tuberculin skin test conversions among DHCP are rare Biosafety www.ehs.columbia.edu Preventing Transmission of TB in Dental Settings Baseline medical surveillance of DHCP (PPD/quantiferon) Assess patients for history of TB Defer elective dental treatment If patient must be treated: • DHCP should wear a respirator • Isolation; separate patient from others/mask • Refer to facility with proper TB infection control precautions Biosafety www.ehs.columbia.edu Questions? Biosafety www.ehs.columbia.edu