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SEXUAL DYSFUNCTIONS, GENDER DYSPHORIA & PARAPHILIC DISORDERS Sexual Dysfunctions: referred to sexual pain or to a disturbance in one or more phases of sexual response cycle. Or : heterogeneous group of disorders that are typically characterized by a clinically significant disturbance in a person's ability to respond sexually or to experience sexual pleasure. Normal Sexual Response Cycle Desire – interest in sexual activity, sexual fantasies Excitement/ Arousal Men – erection Women – vaginal lubrication, clitoral erection, labial swelling, elevation of uterus Plateau Men – increase size of testicle, tightening of scrotal sac, secretion of a few drops of seminal fluid Women - contraction and relaxation of specific part in vagina Orgasm Resolution Dysfunction may occur at one or more of these phases. Lifelong – present from first sexual experiences Acquired – develop after a period of relatively normal sexual function Generalized – not limited to certain types of stimulation, situations, or partners Situational – only occur with certain types of stimulation, situations, or partners Number of factors must be considered during the assessment of sexual dysfunction, given that they may be relevant to etiology and/or treatment, and that may contribute, to varying degrees, across individuals: 1) partner factors (e.g., partner's sexual problems; partner's health status); 2) relationship factors (e.g., poor communication; discrepancies in desire for sexual activity); 3) individual vulnerability factors (e.g., poor body image; history of sexual or emotional abuse), psychiatric comorbidity (e.g., depression, anxiety), or stressors (e.g., job loss, bereavement); 4) cultural or religious factors (e.g., inhibitions related to prohibitions against sexual activity or pleasure; attitudes toward sexuality); and 5) medical factors relevant to prognosis, course, or treatment. Sexual Changes With Aging Aging may be associated with a normative decrease in sexual response Men usually require more direct stimulation of genitals and more time to achieve orgasm. The intensity of ejaculation usually decrease, and the length of refractory period increase After menopause, women experience vaginal dryness and thinning due to decrease estrogen. These conditions can be treated with hormone replacement therapy or vaginal creams Type of Dysfunctions: Male hypoactive sexual desire (desire) Erectile disorder (excitement) Female sexual interest arousal disorder (desire & excitement) Female orgasm disorder (orgasm) Premature ejaculation (orgasm) Delayed ejaculation (orgasm) Genito-pelvic pain penetration disorder Substance/ med induced A) B) C) D) Male Hypoactive Sexual Desire Disorder (Desire) Persistently or recurrently deficient (or absent) sexual/ erotic thoughts or fantasies and desire for sexual activity. The judgement of deficiency is made by the clinician, taking into account factors that affect sexual functioning, such as age and general and sociocultural contexts of the individual’s life The symptoms in Criterion A have persisted for a minimum duration of approximately 6 months The symptoms in Criterion A cause clinically significant distress in the individual The sexual dysfunction is not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress or other significant stressors and is not attributable to the effects of a substance/ medication or another medical condition Male Erectile Disorder (Arousal) A. At least 1 of the 3 following symptoms must be experienced on almost all or all occasions of sexual activity: A. B. C. B. C. D. Marked difficulty in obtaining an erection during sexual activity Marked difficulty in maintaining an erection until the completion of sexual activity Marked decrease in erectile rigidity Symptoms persisted for a minimum duration of approximately 6 months Cause clinically significant distress in individual The sexual dysfunction is not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress or other significant stressors and is not attributable to the effects of a substances/ medication or another medical condition Differential Diagnosis Nonsexual mental disorder. Major depressive disorder and erectile disorder are closely associated Normal erectile function Substance/medication use Another medical condition. A. I. II. III. IV. V. VI. Female Sexual Interest/ Arousal Disorder (Desire&Arousal) Lack of, or significantly reduced, sexual interest/ arousal, as manifested by at least 3 of the following : Absent/ reduced interest in sexual activity Absent/ reduced sexual/ erotic thoughts or fantasies No/ reduced initiation of sexual activity, and typically unreceptive to a partner’s attempts to initiate Absent/ reduced sexual excitement/ pleasure during sexual activity Absent/ reduced sexual interest/ arousal in response to any internal or external sexual/ erotic cues (eg written, verbal, visual) Absent/ reduced sexual genital or nongenital sensations during sexual activity B. C. D. Persists for a minimum duration of approximately 6 months Cause clinically significant distress in individual The sexual dysfunction is not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress (eg partner violence) or other significant stressors and is not attributable to the effects of a substance/ medication or another medical condition Orgasmic Disorders Female Orgasmic Disorder Delayed ejaculation Premature ejaculation Female Orgasmic Disorder Inability to achieve orgasm after a normal excitement phase I. Presence of either of the following symptoms and experienced on almost all occasions of sexual activity marked delay in, marked infrequency of, or absence of orgasm markedly reduced intensity of orgasmic sensations II. Persistent for at least 6 months III. Cause clinically significant distress IV. The sexual dysfunction is not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress (eg partner violence) or other significant stressors and is not attributable to the effects of a substance/ medication or another medical condition Delayed Ejaculation Following symptoms must be experiences on almost all/ all occasions of partner sexual activity, and without the individual desiring delay : A. I. II. B. C. D. Marked delay in ejaculation Marked infrequency or absence of ejaculation Persist for at least 6 months Cause clinically significant distress The sexual dysfunction is not better explained by a nonsexual mental disorder or as consequence of severe relationship distress or other significant stressors and is not attributable to the effects of a substance/ medication or another medical condition Differential Diagnosis Another medical condition: A situational aspect to the complaint is suggestive of a psychological basis for the problem (e.g., men who can ejaculate during sexual activity with one sex but not the other; men who can ejaculate with one partner but not another of the same sex; or men with paraphilic arousal patterns) … Another medical illness or injury may produce delays in ejaculation independent of psychological issues. For example, inability to ejaculate can be caused by interruption of the nerve supply to the genitals, such as can occur after traumatic surgical injury Substance/medication use Dysfunction with orgasm. Premature Ejaculation Ejaculation earlier than desired time. A persistent or recurrent pattern of ejaculation occurring during partnered sexual activity within approximately 1 minutes following vaginal penetration and before the individual wishes it Must have been present for at least 6 months and must be experienced on almost all or all occasions of sexual activity The symptom in Criterion A causes clinically significant distress The sexual dysfunction is not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress or other significant stressors and is not attributable to the effects of a substance medication or another medical condition I. II. III. Genito-pelvic Pain/ Penetration Disorder Persistent or recurrent difficulties with one (or more) of the following Vaginal penetration during intercourse Marked vulvovaginal or pelvic pain during vaginal intercourse or penetration attempts Marked fear or anxiety about vulvovaginal or pelvic pain in anticipation of, during, or as a result of vaginal penetration Persist for at least 6 months Cause clinically significant distress The sexual dysfunction is not better explained by a nonsexual mental disorder or as a consequence of a severe relationship distress or other significant stressors and is not attributable to the effects of a substance/ medication or another medical condition Substance/Medication-Induced Sexual Dysfunction A. B. C. A clinically significant disturbance in sexual function is predominant in the clinical picture There is evidence from the history, physical examination, or laboratory findings of both (1) and (2): 1. 2. D. E. F. The symptoms in Criterion A developed during or soon after substance intoxication or withdrawal or after exposure to a medication The involved substance medication is capable of producing the symptoms in criterion A The disturbance is not better explained by a sexual dysfunction that is not substance/ medication induced The disturbance does not occur exclusively during the course of a delirium The disturbance causes clinically significant distress Differential Diagnosis of Sexual Dysfunction General medical condition : Diabetes, atherosclerosis, pelvic adhesions, alcohol neuropathy, traumatic surgical surgery to the lumbar sympathetic ganglia, abdominoperitoneal surgery, or lumbar symphatectomy Depression & substance abuse : usage of anti depressants, antipsychotic, alpha symphathetic drug, and opiod drugs Abnormal gonadal hormone levels : low estrogen, low testosterone, high progesterone Pharmacological Therapy Erectile ᴕ ᴕ disorder Phosphodiesterase-5 inhibitor (sildenafil only) Alprostadil injected locally Premature ᴕ ᴕ ejaculation SSRIs TCAs Hypoactive ᴕ ᴕ sexual desire disorder Testosterone (both men and women) Estrogen (women only) Treatment of Sexual Disorder Dual sex therapy Behavior therapy Hypnosis Group therapy Analytically oriented psychotherapy Mechanical therapy Male erectile disorders Vacuum pumps, rings, surgery Male orgasmic disorder Gradual progression from extravaginal ejaculation to intravaginal (masturbation) Female orgasmic disorder masturbation (sometimes with vibrator) Premature ejaculation Squeezing technique, stop-start technique Dyspareunia, vaginismus Gradual desensitization, muscle relaxation, dilators GENDER DYSPHORIA Gender dysphoria is a new diagnostic class in DSM-5, is a unique condition in that it is a diagnosis made by mental health care providers. People with this disorder have the subjective feeling that they were born the wrong sex. They may dress as the opposite sex, take sex hormones, or undergo sex change operations. Transgender refers to the broad spectrum of individuals who transiently or persistently identify with a gender different from their natal gender. Transsexual denotes an individual who seek or undergone, a social transition from male to female, or female to male, which is involving a somatic transition by cross-sex hormone treatment and genital surgery (sex reassignment surgery). Gender dysphoria refers to the distress that may accompany incongruence between one’s experienced or expressed gender and one’s assigned gender. Gender assignment refers to the initial assignment as male and female. This occurs usually at birth and, thereby, yields the natal gender. Gender reassignment denotes an official change of gender. Prevalence 1 in every 30,000 males 1 in every 100,000 females Differential diagnosis • • • • Non conformity to gender role Transvestic disorder Body dysmorphic disorder Schizophrenia and other psychotic disorders Gender Dysphoria in Children A. A marked incongruence between one’s experienced/expressed gender and assigned gender, of at least 6 months duration, as manifested by at least six of the following (one of which must be Criterion A1): 1. A strong desire to be of the other gender or an insistence that one is the other gender (or some alternative gender different from one’s assigned gender). 2. In boys (assigned gender), a strong preference for cross-dressing or simulating female attire: or in girls (assigned gender), a strong preference for wearing only typical masculine clothing and a strong resistance to the wearing of typical feminine clothing. 3. A strong preference for cross-gender roles in make-believe play or fantasy play. 4. A strong preference for the toys, games, or activities stereotypically used or engaged in by the other gender. 5. A strong preference for playmates of the other gender. 6. In boys (assigned gender), a strong rejection of typically masculine toys, games, and activities and a strong avoidance of rough-andtumble play; or in girls (assigned gender), a strong rejection of typically feminine toys, games, and activities. 7. A strong dislike of one’s sexual anatomy. 8. A strong desire for the primary and/or secondary sex characteristics that match one’s experienced gender. B. The condition is associated with clinically significant distress or impairment in social, school, or other important areas of functioning. Gender Dysphoria in Adoslescents and Adults A. A marked incongruence between one’s experienced/expressed gender and assigned gender, of at least 6 months duration, as manifested by at least two of the following: 1. A marked incongruence between one’s experienced/expressed gender and primary and/or secondary sex characteristics (or in young adolescents, the anticipated secondary sex characteristics). 2. A strong desire to be rid of one’s primary and/or secondary sex characteristics because of a marked incongruence with one’s experienced/expressed gender (or in young adolescents, a desire to prevent the development of the anticipated secondary sex characteristics). 3. A strong desire for the primary and/or secondary sex characteristics of the other gender. 4. A strong desire to be of the other gender (or some alternative gender different from one’s assigned gender). 5. A strong desire to be treated as the other gender (or some alternative gender different from one’s assigned gender). 6. A strong conviction that one has the typical feelings and reactions of the other gender (or some alternative gender different from one’s assigned gender). B. The condition is associated with clinically significant distress or impairment in social, occupational or other important areas of functioning. Treatment Psychotherapy. Family involvement for young patients. Sex reassignments by hormonal and surgical techniques for adults. Homosexuality Sexual Orientation : The direction of one’s romantic interests and erotic attraction towards a member of the same gender, the other gender or both. Homosexuality : Erotic attraction to and interest in forming romantic relationships with members of one’s own gender (Gays, lesbians) Homosexuality is a sexual or a romantic desire for people of the same sex It’s not a sexual disorder and is a normal variant of sexual orientation True incidence is unknown (< 10 % in both sexes) The etiology is unknown. Homosexuality was once thought to be the result of troubled family dynamic or faulty psychological development Prepubertal same-sex exploratory activities are common and do not significantly latent homosexuality May develop MDD if experiences severe distress because of the conflict between their sexuality and the values of society. Gay and lesbian are often taunted and humiliated in their school/ work settings. Homophobia is a term that refers to the irrational fear and prejudice against homosexual persons Paraphilic disorders Paraphilias are sexual disorder characterized by engagement in unusual sexual activities and/or preoccupation with unusual sexual urges or fantasies At least 6 months that cause impairment in daily functioning Intense, recurrent and interfere with daily life Occasional fantasies are considered normal Most paraphilias occur only in men, but sadism, masochism and pedophilia may also occur in women The most common paraphilias are pedophilia, voyeurism, and exhibitionism Common Paraphilias o o o o o o o o o o Pedophilia Frotterurism Voyerurism Exhibitonism Sadism Fetishism Transvestic fetischism Masochism Necrophilia Telephone scatologia Exhibitionism Diagnostic criteria : A. Over a period of at least 6 months, recurrent, intense sexually arousing fantasies, sexual urges, or behaviors involving the exposure of one's genitals to an unsuspecting stranger. B. The person has acted on these sexual urges, or the sexual urges or fantasies cause marked distress or interpersonal difficulty. Voyeurism Diagnostic criteria : Over a period of at least 6 months, recurrent, intense sexually arousing fantasies, sexual urges, or behaviors involving the act of watching unsespecting nude individuals (often with binocular) to obtain sexual pleasure. B. The person has acted on these sexual urges, or the sexual urges or fantasies cause marked distress or interpersonal difficulty. A. Sadism Diagnostic criteria : A. Over a period of at least 6 months, recurrent, intense sexually arousing fantasies, sexual urges from hurting or humiliating another. B. The person has acted on these sexual urges, or the sexual urges or fantasies cause marked distress or interpersonal difficulty. Masochism Diagnostic criteria : A. Over a period of at least 6 months, recurrent, intense sexually arousing fantasies, sexual urges, or behaviors involving the act (real, not simulated) of being humiliated, beaten, bound, or otherwise made to suffer. B. The fantasies, sexual urges, or behaviors cause clinically significant distress or impairment in social, occupational, or other important areas of functioning. Frotteurism Diagnostic criteria : A. Over a period of at least 6 months, recurrent, intense sexually arousing fantasies, sexual urges, or behaviors involving touching and rubbing against a non-consenting person. B. The fantasies, sexual urges, or behaviors cause clinically significant distress or impairment in social, occupational, or other important areas of functioning. Pedophilia Diagnostic criteria : A. Over a period of at least 6 months, recurrent, intense sexually arousing fantasies, sexual urges, or behaviors involving sexual activity with a prepubescent child or children (generally age 13 years or younger). B. The person has acted on these sexual urges, or the sexual urges or fantasies cause marked distress or interpersonal difficulty. C. The person is at least age 16 years and at least 5 years older than the child or children in Criterion A. Pedophilia Majority involve fondling and oral sex Penetration is infrequent except in incest Offenders report 60% of victims are boys but victim reports are most often girls Most offenders are usually relatives of the victims Fetishism Diagnostic criteria : A. Over a period of at least 6 months, recurrent, intense sexually arousing fantasies, sexual urges, or behaviors involving the use of nonliving objects (e.g., female undergarments). B. The fantasies, sexual urges, or behaviors cause clinically significant distress or impairment in social, occupational, or other important areas of functioning. Transvestic Fetishism Diagnostic criteria A. Over a period of at least 6 months, recurrent, intense sexually arousing fantasies, sexual urges, or behaviors involving cross-dressing. B. The fantasies, sexual urges, or behaviors cause clinically significant distress or impairment in social, occupational, or other important areas of functioning.