Download Curriculum Vitae - Ruysdael Clinics

Curriculum Vitae
PERSONAL
Name:
Born:
Marital status:
Marcel Paul Copper.
March 7, 1963 in The Hague, the Netherlands.
Married, 4 children.
EDUCATION/EMPLOYMENT
1975-1981
VWO: Caland Lyceum, Rotterdam, the Netherlands.
1981-1988
Medicine, University of Leiden, the Netherlands.
1984: Research cardiology, Edinburgh, Scotland.
Student-assistant positions: Anatomy, neuroanatomy, social
health and medical informatics.
1988-1990
First Lieutenant doctor: Military Hospital Dr. A. Mathijsen,
Department of Otolaryngology, Utrecht, the Netherlands.
1990 (March-Sept)
Resident in general surgery, Diaconessenhuis, Leiden, the
Netherlands.
1990-1992
Researcher: Tumour Biological Laboratory of the Department of
Otolaryngology, head and neck surgery, Free University Hospital,
Amsterdam, the Netherlands.
1992-1997
Training for Otolaryngologist: Free University Hospital,
Amsterdam, the Netherlands. Trainers: Prof. Dr. G.B. Snow, Prof.
Dr. I.B. Tan. Registration as an Otolaryngologist: April 1, 1997.
1997-1999
Academic specialist, Academic Medical Centre, Amsterdam, the
Netherlands. Focus areas: Head and neck surgery, Otology and
Paediatric Otolaryngology.
March 1998
PhD in Medicine, Free University, Amsterdam, the Netherlands.
Thesis: Biomarkers in chemoprevention of second primary tumours
in head and neck cancer patients. Promotor: Prof. Dr. G.B. Snow.
1999-2000
Fellowship in Head and neck surgery, Netherland Cancer Institute,
Amsterdam, the Netherlands.
2000-March 2002
Head and neck surgeon, Free University Hospital, Amsterdam, the
Netherlands. Focus areas: Oncology, reconstructive surgery.
2001-2008
Consultant Head and neck surgeon, Emma Children’s Hospital
and Academic Medical Centre, Amsterdam, the Netherlands.
- Dr. M.P. Copper, -1 -
2002-2008
Head and neck surgeon, Netherland Cancer Institute, Amsterdam,
the Netherlands.
2002-present
Otolaryngologist/Head and neck surgeon, Sint Antonius Hospital,
Nieuwegein, the Netherlands. Focus areas: Head and neck surgery
and surgery for obstructive sleep apnea syndrome.
2008-present
Trainer in Otolaryngology, Sint Antonius Hospital,
Nieuwegein/Utrecht, the Netherlands.
2016-present
ENT-surgeon at the Ruysdael Voice Clinic, Amsterdam, the
Netherlands.
OTHER POSITIONS AND MEMBERSHIPS
Member of the Dutch Society for Otolaryngology/Head and neck surgery.
Member Dutch Committee for Eye and Orbital Tumours.
Member of the Dutch Guideline Committee for Oesophageal Cancer.
Board member (Secretary) of the ENT association of the Central Netherlands.
Board member (Finance) of the medical staff, Sint Antonius Hospital, Nieuwegein.
Member of the Dutch Consilium of Otolaryngology.
Member of the Dutch Visitation Committee for Teaching Hospitals in Otolaryngology.
Member of the European Laryngological Society.
International member American Academy of Otolaryngology - Head & Neck Surgery.
Corresponding member American Head and Neck Society.
Member of the Dutch Working group on OSAS.
Member of the International Sleep Surgical Sleep Society.
Representative of Dutch Society for Otolaryngology/ Head and neck surgery at the RGS
(Registration committee of Medical Specialists).
PRICES
1994: Annual Award of the Dutch Association of Oral Surgery and Oral Surgery for
research on genetic factors in head and neck cancer.
1999: Annual Award (2nd) of the Dutch Society of Otolaryngology/Head and neck surgery
for the thesis “Biomarkers in chemoprevention of second primary tumours in head
and neck cancer patients”.
- Dr. M.P. Copper, -2 -
PUBLICATIONS
Thesis
Biomarkers in chemoprevention of second primary tumours in head and neck cancer patients.
ISBN 90-9011394-0, march 1998.
Scientific publications
1
C.F. Smit, M.P. Copper, J.M.G. Urlings. Two HIV-seropositive militaries having ENTcomplaints. Dutch Military Journal of Medicine, 5:163-165 (1990).
2
M.P. Copper, B.J.M. Braakhuis, N. de Vries, G.A.M.S. van Dongen, J.J.P. Nauta,
G.B. Snow. A panel of biomarkers of carcinogenesis of the upper aerodigestive tract
as potential intermediate end points in chemoprevention trials. Cancer, 71:825-830
(1993).
3
J. Cloos, I. Steen, B.J.M. Braakhuis, M.P. Copper, N. de Vries, J.J.P. Nauta, G.B.
Snow. Increased mutagen sensitivity in head-and-neck squamous-cell carcinoma
patients, particularly those with multiple primary tumors. International Journal of
Cancer, 56:816-819 (1994).
4
M.P. Copper, A. Jovanovic, J.J.P. Nauta, B.J.M. Braakhuis, N. de Vries, I. van der
Waal, G.B. Snow. Role of genetic factors in the etiology of squamous cell carcinoma of
the head and neck. Archives of Otolaryngology Head and Neck Surgery, 121:157-60
(1995).
5
L.J.J.M. Bauwens, M.P. Copper, J.T. Schmidt. Life-threatening angioedema as a side
effect of angiotensin-converting-enzyme (ACE) inhibitors. NTVG, 139:674- 677 (1995).
6
J.A.M. Beliën, M.P. Copper, B.J.M. Braakhuis, G.B. Snow, J.P.A. Baak.
Standardization of counting micronuclei: definition of a protocol to measure genotoxic
damage in human exfoliated cells. Carcinogenesis, 16:2395-2400 (1995).
7
M.P. Copper, F.B.J.M. Thunnissen, N. de Vries, G.B. Snow, B.J.M. Braakhuis.
Cytomorphometric parameters in exfoliated cells as biomarkers in head and neck
cancer chemoprevention. International Journal of Oncology, 9:1071-1075 (1996).
8
T. Teerlink, M.P. Copper, I. Klaassen, B.J.M. Braakhuis. Simultaneous analysis of
retinol, all-trans- and 13-cis-retinoic acid and 13-cis-4-oxoretinoic acid in plasma by
liquid chromatography using on-column concentration after single-phase fluid
extraction. Journal of Chromatography B, 694:83-92 (1997).
9
J.W. Wirds, E.S. Boon, G.J. Scheffer, M.P. Copper, H.F. Mahieu. Percutaneous
tracheotomy using a dilating forceps: a rapid and safe technique. Intensive Care
Reviews, 12:9-14 (1997).
10
B.J.M. Braakhuis, I. Klaassen, B.M. van der Leede, J. Cloos, R.H. Brakenhoff, M.P.
Copper, T. Teerlink, H.F.J. Hendriks, P.T. van der Saag, G.B. Snow. Retinoid
metabolism and all-trans retinoic acid induced growth inhibition in head and neck
squamous cell carcinoma cell lines. British Journal of Cancer, 76:189-197 (1997).
- Dr. M.P. Copper, -3 -
11
M.P. Copper, R.H. Brakenhoff, J. Cloos, G.B. Snow, B.J.M. Braakhuis. All-trans
retinoid acid induced gene expression and growth inhibition in head and neck cancer
cell lines. European Journal of Cancer Part B: Oral Oncology, 33:270-274 (1997).
12
I. Klaassen, M.P. Copper, R.H. Brakenhoff, S.J. Smeets, G.B. Snow, B.J.M.
Braakhuis. Exfoliated oral cell messenger RNA - suitability for biomarker studies.
Cancer Epidemiology, Biomarkers & Prevention, 7:469-472 (1998).
13
H.A.J. Brok, R.J. Stroeve, M.P. Copper, P.F. Schouwenburg. The treatment of
hypertonicity of the pharyngo-oesophageal segment after laryngectomy: a review.
Clinical Otolaryngology, 23:302-307 (1998).
14
M.P. Copper, I. Klaassen, T. Teerlink, G.B. Snow, B.J.M. Braakhuis. Plasma
retinoid levels in head and neck cancer patients: a comparison with healthy controls
and the effect of retinyl palmitate treatment. European Journal of Cancer Part B:
Oral Oncology, 35:40-44 (1999).
15
H.A.J. Brok, M.P. Copper, R.J. Stroeve, B.W. Ongerboer de Visser, A.J. Venkervan Haagen, P.F. Schouwenburg. Evidence for recurrent laryngeal nerve
contribution in motor innervation of the human cricopharyngeal muscle.
Laryngoscope, 109:705-708 (1999).
16
M.P. Copper. Biomarkers for chemoprevention of second primary tumors in the head
and neck. Kanker, 23(2):30-31 (1999).
17
D.J. Menger, M.P. Copper, R.A. Tange, P.F. Schouwenburg. An extraordinary cause
of nasal obstruction: A leiomyosarcoma. NTvKNO, 2:62-65 (1999).
18
M.P. Copper, C.F. Smit, L.D. Stanojcic, P.P. Devriese, P.F. Schouwenburg, E.M.H.
Mathus-Vliegen. The role of laryngo-pharyngeal reflux in head and neck cancer
patients. Laryngoscope, 110:1007-1011 (2000).
19
P. Merkus, M.P. Copper, M.H.J. van Oers, P.F. Schouwenburg. Lymphoma in the
ear. ORL J Otorhinolaryngol Relat Spec, 62:274-277 (2000).
20
C.F. Smit, M.P. Copper, J.A.M.J. van Leeuwen, I.G. Schoots, L.D. Stanojcic. Effect
of cigarette smoking on laryngopharyngeal and gastro-oesophageal reflux. Annals
of Otology, Rhinology and Laryngology, 110:190-193 (2001).
21
I.B. Tan, J.L.N. Roodenburg, M.P. Copper, J.W.W. Coebergh, I. van der Waal. Early
diagnosis and prevention of malignant tumors in the head and neck region. NTVG,
145:567-572 (2001).
22
Buwalda J, Schouwenburg PF, Blank LE, Merks JH, Copper MP, Strackee SD,
Voute PA, Caron HN. A novel local treatment strategy for advanced stage head and
neck rhabdomyosarcomas in children. Results of the AMORE protocol. Eur J Cancer,
39:1594-602 (2003).
23
M.P. Copper, I.B.Tan, H. Oppelaar, M.C. Ruevekamp, F.A. Stewart. Foscan
mediated photodynamic therapy in early stage squamous cell carcinoma of the head
and neck. Archives of Otolaryngology Head and Neck Surgery, 129:709-711 (2003).
24
J. Buwalda , L.E. Blank, P.F. Schouwenburg, M.P. Copper, S.D. Strackee, P.A.
Voute, J.H. Merks, H.N. Caron. The AMORE protocol as salvage treatment for nonorbital head and neck rhabdomyosarcoma in children. Eur J Surg Oncol, 30:884892 (2004).
- Dr. M.P. Copper, -4 -
25
C.E. Lopuhaä, M.P. Copper, A.J.M. Balm. Obstructive sleep apnea syndrome in a
child. NTvKNO, 11:143-145 (2005).
26
A.J.M. Balm, P.F.J.M. Lohuis, M.P. Copper. Educational session: How I do it Unwrapping the neck node levels around a sternocleidomastoid muscle bar: a
systematic way of performing (modified) radical neck dissection. Eur J Surg Oncol.
31:1216-1221 (2005).
27
L. Smeele, I.B. Tan, M.P. Copper. Foscan-mediated photodynamic therapy (PDT) in
the treatment of primary squamous cell carcinoma of the head and neck. Int J Oral
Maxillofac Surg. 34:38-38 (2005).
28
M.P. Copper, M. Triesscheijn, I.B. Tan, M.C. Ruevekamp, F.A. Stewart.
Photodynamic therapy in the treatment of multiple primary tumors in the head and
neck. Clin Otolaryngol, 32:185-9 (2007).
29
B. Karakullukcu, K. van Oudenaarde, M. Copper, M. Klop, R. van Veen, B. Tan.
Photodynamic therapy of early stage oral cavity and oropharynx neoplasms: an
outcome analysis 170 patients. Eur Arch Otorhinolaryngol. 268:2810288 (2011).
30
D.M.J. Milstein, A.M. van Kuijen, M.P. Copper, W.F. Fokkens, I.B. Tan, C. Ince.
Monitoring microcirculatory alterations in oral squamous cell carcinoma following
photodynamic therapy. Photodiagnosis Photodyn Ther, 9:69-75 (2012).
31
B. Karakullukcu S.D. Stoker, A.P. Wildeman, M.P. Copper, M.A. Wildeman I.B.
Tan. A matched cohort comparison of mTHPC-mediated photodynamic therapy
and trans-oral surgery of early stage oral cavity squamous cell cancer. Eur Arch
Otorhinolaryngol, 270:1093-7 (2013).
32
S. van Egmond, A. Aarts, M.P. Copper. Effect of multilevel surgery in patients
with obstructive sleep apnea syndrome. NTvKNO, 20:45-9 (2014).
PRESENTATIONS
November 1990, Amsterdam. First Euroscan-meeting: "Current status of the Euroscan
trial".
June 1991, Amsterdam. EORTC head and neck group meeting: "Euroscan, present status".
September 1991, Düsseldorf, Germany. IV Symposium on Tumor Research in Oto-RhinoLaryngology: "Head and neck cancer risk assessment by biological markers".
October 1991, Vittorio Veneto, Italy. Convegno Internazionale Il Carcinoma Faringo
Laringeo:"Euroscan: Uno studio europeo sulla chemio-prevenzione dei secondi tumori
primitivi".
October 1991, Verona, Italy. Euroscan-meeting: "Euroscan, present status".
October 1991, Baton Rouge, USA. Symposium on Vitamins and Cancer Prevention:
"Euroscan, present status".
March 1992, Amsterdam. 7th NCI-EORTC Symposium on new drugs in cancer therapy:
"Intermediate endpoints in chemoprevention trials".
- Dr. M.P. Copper, -5 -
November 1992, Amsterdam.
chemoprevention trials".
NWHHT-conference:
"Intermediate
end-points
in
March 1993, Nijmegen. KNO-vergadering: "Erfelijke factoren spelen een belangrijke rol
bij het ontstaan van het plaveisel-celcarcinoom in het hoofd-halsgebied: een patiëntcontrole-onderzoek".
April 1993, Berlin, Germany. International Cancer Chemo Prevention Conference:
"Intermediate markers in the Euroscan trial".
May 1995, Brussels, Belgium. EORTC head and neck group meeting: "Biomarkers and
their application in cancer chemoprevention".
November 1996, Amsterdam. 9e symposium experimenteel onderzoek heelkundige
specialismen: "Nieuwe risicofactoren voor het ontwikkelen van een plaveiselcelcarcinoom
in het hoofd-hals gebied".
January 1997, Haarlem. KNO-vergadering: “De percutane punctie-tracheotomie: Een
beschrijving en analyse van twee verschillende methoden”.
May 1998, Arcachon, France. 1st European week on the larynx: “Recurrent laryngeal
nerve contribution in motor innervations of the human crico-pharyngeal muscle”.
June 1998, Helsinki, Finland. 7th International congress of pediatric otorhinolarygology:
“A new combined treatment of surgery, brachytherapy and reconstruction in children
with recurrent rhabdomyosarcoma after chemotherapy: The AMORE-protocol”.
September 1998, Rome, Italy. Second congress of the European Laryngological Society:
“Recurrent laryngeal nerve contribution in motor innervations of the human cricopharyngeal muscle”.
April 1999, Amsterdam. KNO-vergadering: “Biomarkers bij chemopreventie van tweede
primaire tumoren in patiënten met een hoofd-hals carcinoom”.
November 1999, Groningen. KNO-vergadering: “Laryngofaryngeale reflux bij patiënten met
een carcinoom in het hoofd-hals gebied”.
November 1999, Epe. Lustrummeeting Nederlandse Werkgroep Hoofd-Halstumoren:
“Biomarkers bij chemopreventie van hoofd-hals tumoren: een update”.
March 2001, Amsterdam. Refereeravond VUMC: “Chemopreventie bij het hoofdhalscarcinoom”.
October 2001, Moerkapelle. Symposium
“Larynxcarcinomen en spraakrevalidatie”.
&
Workshop
OK-assistenten
KNO:
May 2002, Boca Raton, USA. American Head & Neck Society (Combined Otolaryngological
Spring Meetings): “Foscan® mediated photodynamic therapy in early stage squamous cell
carcinoma of the head and neck”.
September 2002, San Diego, USA. American Academy of Otolaryngology - Head and Neck
Surgery. Laryngopharyngeal Reflux: What to Do in the Normal ENT Practice (instructor).
- Dr. M.P. Copper, -6 -
November 2002, Amsterdam. KNO-vergadering:“Lange termijn resultaten van Foscan®
gereguleerde fotodynamische therapie bij de behandeling van oppervlakkige hoofdhalscarcinomen.”
November 2002, Rio de Janeiro, Brazil. 8th World Congress on Oral Cancer. Workshop
Photodynamic Therapy (invited speaker).
May 2003, Koln, Germany. Course on PDT (instructor)
September 2003, Amsterdam. Course on PDT (instructor)
July 2004, Amsterdam. NDDO-meeting: ”Recognizing patients who can benefit from
PDT.”
March 2005, Liverpool, England. Aintree Hospital: ”Head and Neck cancer treated by
Photodynamic Therapy.”
March 2005, UMCU. Refereeravond: ”De behandeling van hoofd-hals tumoren met
photodynamische therapie.”
November 2005, Nieuwegein. KNO-vergadering: ”Results of Foscan® mediated
photodynamic therapy in the treatment of second primary tumors in the head and neck”.
November 2006, Amsterdam. Opening PDT-centre: ”Photodynamic therapy and head and
neck cancer”.
January 2007, Dordrecht. Masterclass BAHA: ”Suturing and bandages”.
March 2008, Nieuwegein. Sleepmarket 2008: ”De surgical treatment of OSAS”.
January 2009, Nieuwegein. Department of surgery: ”Algorithm Neck node”.
September 2010, Nieuwegein. Reflux course ATOS Medical: ”Techniques in measuring
laryngopharyngeal reflux”.
October 2010, Nieuwegein. Najaarsvergadering NSWO: ”Multilevel Surgery in untreated
OSAS patients”.
January 2013, Nieuwegein. BAHA Master class. Introduction and new developments.
March 2015, Nieuwegein, National Symposium on Anaesthesia and OSAS. Surgical
treatment options for OSAS.
April 2015, Nieuwegein, NVTS (Dutch Society of Dental Sleep Medicine). New surgical
treatment options for OSAS.
October 2015, Veldhoven, Dutch Surgery Days. Hypoglossal nerve stimulation: a new
surgical treatment option for OSAS.
February 2016, Frankfurt, Germany. DISE for patient selection in UAS therapy.
- Dr. M.P. Copper, -7 -