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Nieuwjaarsreceptie
Faculteit Bètawetenschappen
7 januari 2014
VERBINDEN
Johan Garssen
•Pharmacology (UIPS), Beta Faculty, UU
•Immunology, Nutricia-research (Utrecht/
Singapore), DANONE
Verbinden (oud en nieuw)
Verbinden van mensen
Verbinden van culturen
Verbinden van onderzoekers, expertises
Verbinden van food en pharma
Verbinden van public en private
Fast changing environment
Fast changing environment
Bridging (life sciences) between
different cultures/continents
Bridging life sciences between
profit and non-profit organisations
[valorisation]
Disease
Drugs/Specialised nutrition
Therapy and Prevention
UIPS:Translational medicine
Mission: From bench/molecule to bedside
Translational pharmacology
In vivo
Animal
In vivo
Human
In vivo
Human
(multi center
trial)
(proof of
concept)
In vitro
Animal
Cells
In vitro
Human
Cells
In vitro Mechanistic
Use-inspired fundamental research
Embedding in Life Sciences Utrecht
(present collaborations)
Hubrecht,
developm. biol.
Stem cells.
WKZ
immunology
Nutricia/DANONE
-research
UIPS
Beta faculty
U Med.Center
microbiol.
oncology
metabol. &
endocrin.
pathol.
Allergy
Lung
Stratenum
CNS
Cell Biol.
HU
Life sciences
Proteomics
IRAS
BIOCEROS
RIVM
HU
health
Vet. Sci.
infect. diseas. &
immunol
Pharmacology
Arthritis team
MRI analysis
Imaging Science
Institute
Respiratory
microbiota
Immunology
Infectious
Diseases
Prof Viergever
Prof Sanders
Animal studies
Biomarkers
UIPS
Prof Garssen
Dr Kraneveld
NutriBrain
study
Neonatology
Dr Benders
Prof Van Bel
WUR
Wageningen
Placenta
Biomarkers
Pathology
Dr Nikkels
Gut
development
faecal
microbiota
Immune
Biomarkers
Translational
Immunology
Prof Prakken
Prof Knol
Dr Belzer
1
"Let medicine be thy food,
and food be thy medicine.“
Hippocrates of Cos, Greece
460-377 B.C.
Nutrition
Pharma
• Education: Junior college, Bachelor,Master,PhDs,
Eureka
• Awareness (….single vs. multitarget approach)
• Translational research  valorisation
Bio-active components in pharma
versus food
Focussed large effect on
single target
Small effects on
multiple targets
Pharma
Food
From single towards multitarget approaches
(cancer)
Cachexia
Malnutrition
Fatigue
Systemic inflammation
Infections
Mucositis
…
MEDICAL NUTRITION
UTRECHT/SINGAPORE
COMPANIES
Translational Medicine
from bench to bedside
2014 
1. PUBLIC PRIVATE: speeding up innovation
2. Asia vs Europe/VS: differences in biomarkers
health/disease, success of intervention
3. Gap between food and pharma is narrowing
(single vs multitarget approach)
4. Connect research with education