Download syllabus - srm.cse.section-a

BIOLOGY FOR ENGINEERS
Total Contact Hours - 30
LTPC
2002
Prerequisite
Nil
PURPOSE
The purpose of this course is to provide a basic understanding of biological mechanisms of living
organisms from the perspective of engineers. In addition, the course is expected to encourage
engineering students to think about solving biological problems with engineering tools.
INSTRUCTIONAL OBJECTIVES
1. To familiarize the students with the basic organization of organisms and subsequent building to a
living being
2. To impart an understanding about the machinery of the cell functions that is ultimately
responsible for various daily activities.
3. To provide knowledge about biological problems that requires engineering expertise to solve
them
UNIT I BASIC CELL BIOLOGY AND MOLECULAR BIOLOGY 10 hrs.
Cell structure and function of cell organelles, Eukaryotic and prokaryotic cells, Cell division, Mitosis,
Meiosis, Central Dogma of life DNA, RNA & Protein synthesis, Genetic information
UNIT II BIO-ORGANIC CHEMISTRY, ENZYMES AND INDUSTRIAL APPLICATIONS 6hours
Introduction to Carbohydrates, fats, proteins-structure, function, classification, Enzymes: Biological
catalysts, Classification of Enzymes, Proteases, Carbonic anhydrase, Restriction enzymes, Enzyme
immobilization.
UNIT III GROWTH KINETICS AND MICROBIAL TECHNOLOGY 4 hrs.
Phases of microbial growth, Microbial growth curve, Cell growth kinetics,-Batch and continuous
growth, Sterilization kinetics.
UNIT IV FERMENTATION TECHNOLOGY & DOWNSTREAM PROCESSING 4 hrs.
Fermentation- basic definition, Types of media and components, Fermentors and their types, Airlift
fermentor, Continuous stirred tank fermentor. Stages in downstream operations, Purification by
Chromatography.
UNIT V MECHANOCHEMISTRY- NERVOUS SYSTEM, IMMUNE SYSTEM, AND CELL SIGNALING 6 hrs.
Molecular Machines/ Nervous system-Motors—Cytoskeleton—Bioremediation—Biosensors,
Immune system/Immunity- General principles of cell signalling
TEXT / REFERENCE BOOKS:
1. Satyanarayana, Biotechnology, 4th Edition, Books and Allied (p) Ltd. 2005-01-01, ISBN .
2. Lehninger A.L, Nelson D.L, Cox .M.M, Principles of Biochemistry. CBS Publications 1993
3. Shuler.M.L. and Kargi.F, Bioprocess Engineering 1st Edition. Pearson Education India, 2003.
4. Stanbury P.F., A.Whitaker, and Hall S.J. , Principles of Fermentation Technology, 2nd Edition,
Butterworth-Heinemann 1997.