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Dr. KK Rana, Asstt. Professor (Stage-3), Gushkara
Mahavidyalaya
GENERAL INFORMATION
1. Name:
Dr. Kalyan Kumar Rana
2. Father’s name:
Late Sudhir Chandra Rana
3. Department:
Department of Chemistry
4. Current Designation:
Assistant Professor (Stage-3)
5. Address for correspondence
: Dr. Kalyan Kumar Rana
Opp-Puratanchak Ration Shop, PO-Nutanganj
Sher Afghan Road, PS+Dist-Burdwan
PIN-713102, WB.
6. Permanent Address (with pin code): Dr. Kalyan Kumar Rana
Opp-Puratanchak Ration Shop,
Sher Afghan Road, PO-Nutanganj
PS+Dist-Burdwan, PIN-713102, WB.
7. Educational Qualification (Graduation onwards):
Examination
BSc
MSc
PhD(Sc)
Name of the Affiliating
University
Vidyasagar University
Vidyasagar University
Jadavpur University
Year of
passing
1994
1996
2002
NET
GATE
---
2000 (June)
1996 and
1997
Name of Institution
Pravat Kumar College, Contai
Vidyasagar University, MIdnapore
Indian Association for the
Cultivation of Science, Jadavpur
-----
Some Presentable Information
Dr. KK Rana has joined in the Gushkara Mahavidyalaya on 01.03.2003 as a Lecturer in
Chemistry and continuing till date as an Associate Professor (Stage-3) of Chemistry.

JRF, SRF and RA(I) at Indian Association for the Cultivation of Science, 2A, 2B
Raja SC Mallick Road, Jadavpur, Kolkata-32.

Post Doctoral Research Associate at North Dakota State University, North
Dakota, USA, under the supervision of Prof. MP Sibi, Dept. of Chemistry and
Biochemistry.

Attended one ‘Orientation Programme’ and three ‘Refresher Courses’ specified
for College Teachers, Organized by the UGC-Academic Staff College, The University of
Burdwan.

Attended Seven Retraining Programmes of College Teachers, organized by
Jadavpur University, Jadavpur, Kolkata, under UGC-JU Potential for Excellence
Scheme.

Attended a number of Seminars, Symposia, Conferences Summer and Winter Schools
etc. related to Chemistry.

Published 17 Research Papers in Internationally Reputed Journals.

Published 2 Text Books on UG Chemistry Practical Courses.

Published 2 Edited Volumes.

Obtained Silver Medal from Vidyasagar University as stood second in 1996 MSc
(Chemistry) batch.

Regarding Research:
Have
Ability to perform synthetic organic chemical reactions and to purify the
products in micro scale.
Expertise in handling air and moisture sensitive compounds like epoxides,
bromides, epoxyolefinic compounds etc.
Experience in analysis of 1H, 13C, DEPT NMR and mass spectra. Interpretation
of GC-MS, EI-MS, GC, paper chromatography and handling HPLC, FT-IR etc.
Working knowledge in MSWord, MSPowerPoint, MSExcel, ChemWindow,
Chemdraw, Chemoffice etc.
Obtained a Minor Research Project Proposal to UGC, ERO. Title of the
project is “Development of an efficient and convenient protocol for the synthesis of
polyfunctionalized benzopyrans by a three-component one-pot coupling reaction using
molybdenylacetylacetonate as the catalyst”
 Life Member: Indian Association for the Cultivation of Science, Jadavpur, Kolkata-32
[Mem. No. 3687/17-4-97].
 Member: Indian Chemical Society, 92 APC Road, Kolkata-9 [Mem. No. 5811].
 Life Member: The Indian Science Congress Association, 14, Dr. Biresh Guha Street,
Kolkata-17 [Mem. No. L21169].
 Life Member: Indian Science News Association, 92, APC Roy Road, Kolkata-9 [Mem.
No. LM 805].
 Life Member: Udbodhan, 1, Udbodhan Lane, Baghbazar, Kolkata- 3 [Mem. No. LK312P]
Participation in Seminars, Conferences etc.
Sl.
No.
Name of OP/RC/Workshop/
Seminar/Symposia
Organized by
Venue
Date
1.
56th Orientation Programme
UGC-ASC, Burdwan University
UGC-ASC, Burdwan
University
21st Dec., ’05 17th Jan., ’06
2.
Empowerment of Women
MUC Women’s College,
Burdwan
MUC Women’s
College
Burdwan
24th & 25th
Feb., 2005
3.
3rd Chemical Research
Society of India Symposium
IIT,
Kharagpur
6th Aug., 2005
4.
42nd Annual Convention of
Chemists
9th-13th Feb.,
2006
5.
Retraining of College
Teachers on Development of
Scientific Awareness
Jadavpur
University
6.
Retraining of College
Teachers on “Placement
Network Management”
Jadavpur
University
Dept. of Chemistry
Visva Bharati
Santiniketan
Dept. of
Instrumentation
Engineering,
Jadavpur
University
Dept. of Mechanical
Engineering,
Jadavpur
University
7.
4th Chemical Research
Society of India Symposium
Chemical Research Society of
India and Dept. of Chem.
Kalyani University
Chemical Research Society of
India and Department of
Chemistry, IIT, Kharagpur
Indian Chemical Society and
Department of Chemistry,
Visva Bharati, Santiniketan
Kalyani
University
University College
of Science and
Technology,
University of
Calcutta, Rajabazar,
Kolkata-9.
Department of
Power Engg.
Jadavpur
University.
10th -11th
Mar., 2006
21st Mar., 2006
4th Aug.,
2006
8.
Acharya Prafulla Chandra Ray
and Chemistry Today
Indian Chemical Society
9.
Retraining of College
Teachers on “Placement
Office Management”
Jadavpur University
10.
International Symposium on
Current Perspectives in
Organic Chem.
Dept. of Organic Chemistry,
Indian Association for the
Cultivation of Science,
Jadavpur
MLS Hall, IACS,
Jadavpur
Kol-32
7th-9th Dec.,
2006
Jadavpur University
Dept. of Mech.
Engg., Jadavpur
University
5th Jan., 2007
Jadavpur University
Dept. of
Mathematics,
Jadavpur University
16th Jan.
2007
Dept. of
Mathematics,
Jadavpur University
Dept. of
Architecture,
Jadavpur University
Raj College,
Burdwan
19th Jan.
2007
11.
12.
13
14
15
Retraining of College
Teachers on “Science
Education and Development
of Scientific Bent of Mind.”
Retraining of College
Teachers on “Scope of
Research in Science and
Engineering.”
Retraining of College
Teachers on “Computer Aided
Teaching.”
Retraining of College
Teachers on “Redesigning of
an Existing Syllabus.”
The proposed Indo-US
Nuclear Treaty: Implication
Jadavpur University
Jadavpur University
WBCUTA, Burdwan Distt..
Committee
15th Sep., 2006
24th Nov.,
2006
5th Feb.
2007
8th Dec., 2007
and Significance
16
17
18
19
20
21
22
UGC-Sponsored National
Seminar on “Advanced
Spectroscopy, Theoretical
Chemistry, Synthesis,
Reactivity and Structure
Evaluation.”
Summer School on
“Corrosion Fundamentals,
Testing and Prevention.”
Seminar on “Education: Past
and Present”
15th Refresher Course on
Environmental Science
Winter School on “Waste
Mgmt., Effluent Treatment and
Recycling.”
UGC Sponsored State Level
Seminar on “Tourism: An
Activity for Economic and
Socio-Cultural Boost”
UGC Sponsored State Level
Seminar on “Bio-Diversity:
Issues and Concerns”
23
‘Prabodh’ Certificate Course
in Hindi
24
National Workshop on
SCILAB
25
26
27
UGC and State DST
Sponsored National Seminar
on “Design, Synthesis,
Interaction, Chemical and
Biochemical Activities of
Different Functional
Molecules”
Chemical Research Society of
India Symposium on
“Chemical Research in the
First Decade of 21st Century”
20th Refresher Course on
Environmental Science
28
Science Academies’ Lecture
Workshop on “Recent
Developments in Chemistry”
29
UGC Sponsored National
Level Seminar on “Advanced
Instruments used in Current
Research”
30
UGC Sponsored National
Level Seminar on “Frontier in
Chemistry”
The University of Burdwan,
Dept. of Chemistry
Deptt. of Chemistry
25th-27th Apr.,
2008
MHRD/AICTE under Staff Dev.
Programme
Dept. of Chemistry,
NIT, Durgapur
14th to 27th
July, 2008
Gushkara
Mahavidyalaya
UGC-ASC, Burdwan
University
25th Sept., 2008
MHRD/AICTE under Staff Dev.
Programme
Dept. of Chemistry,
NIT, Durgapur
19th to 31st
Jan., 2009
Gushkara Mahavidyalaya and
BN Dutta Smriti
Mahavidyalaya, Burdwan
Gushkara
Mahavidyalaya
26th March,
2010
Gushkara
Mahavidyalaya
27th March,
2010
Distance Mode
November,
2010
Haldia Institute of
Technology, Haldia
27th-29th Dec.,
2010
Deptt. of Chemistry
15th-17th March,
2011
Gushkara Mahavidyalaya
UGC-ASC, Burdwan University
Gushkara Mahavidyalaya and
BN Dutta Smriti
Mahavidyalaya, Burdwan
Hindi Teaching Scheme
(Exam. Wing),
Department of Official
Language,
Ministry of Home Affairs,
Govt. of India
School of Applied Sciences
and Deptt. Information
Technology, HIT Haldia and
FOSSEE—Project of IIT
Bombay
The University of Burdwan,
Deptt. of Chemistry
Chemical Research Society of
India and Department of
Chemistry, Visva Bharati,
Santiniketan
UGC-ASC, Burdwan University
Department of Chemistry,
Visva Bharati, Santiniketan
Department of Chemistry &
Physics, Dept. of Sri
Ramakrishna Sarada Vidya
Mahapitha, Kamarpukur and
Dept. of Physics, The
University of Burdwan
Department of Chemistry,
MUC Women’s College and
Department of Chemistry,
Vivekananda Mahavidyalaya,
23rd Dec.,’08 12th Jan., ’09
Department of
Chemistry, Visva
Bharati,
Santiniketan
UGC-ASC, Burdwan
University
Department of
Chemistry, Visva
Bharati,
Santiniketan
15th Oct.- 04th
Nov., ’11
Sri Ramakrishna
Sarada Vidya
Mahapitha,
Kamarpukur
20th-21st Sept.,
2013
MUC Women’s
College
4th-5th Dec.,
2013
6th Aug., 2011
29th Nov.-1st
Dec., 2012
Burdwan
Department of
Chemistry, Visva
Bharati,
Santiniketan
Department of
Chemistry, Visva
Bharati,
Santiniketan
31
Science Academies’ Lecture
Workshop on “Recent
Developments in Chemistry”
Department of Chemistry,
Visva Bharati, Santiniketan
32
National Seminar on “Recent
Advances in Chemistry”
Department of Chemistry,
Visva Bharati, Santiniketan
33
National Symposium on
“Recent Advances in
Chemistry and Industry
(2014)”
Indian Chemical Society,
Kolkata
Meghnad Saha
Bhavan, 92, APC
Road, Kolkata-9
1st-2nd Aug.,
2014
34
National Symposium on
“Opportunities in Medicinal
Plant Research”
Society for
Ethnopharmacology and
School of Natural Product
Studies, Jadavpur University
Gandhi Bhavan,
Jadavpur
University,
Jadavpur, Kolkata32
29th-30th
Nov., 2014
Sitananda College, Nandigram
and Royal Society of
Chemistry (Eastern India
Section)
Sitananda College,
Nandigram, Purba
Medinipur
12th Dec., 2014
UGC-ASC, Burdwan University
UGC-ASC, Burdwan
University
24th-30th Dec.,
2014
UGC-ASC, Burdwan University
UGC-ASC, Burdwan
University
30th Jan.- 19th
Feb., 2015
Dept. of Chemistry, Gushkara
Mahavidyalaya, Gushkara,
Burdwan
SN Bose Hall,
Gushkara
Mahavidyalaya
22nd March,
2015
Department of Chemistry,
Haldia Govt. College,
Haldia, Purba Medinipur
Auditorium, Haldia
Govt. College,
Haldia, Purba
Medinipur
4th - 5th August,
2016
35
36
37
38
39
National Symposium on
“Chemistry and its Interface
with the Scientific
Disciplines”
2nd Short Term Course on
“Students’ Counseling and
Guidance”
1st RC in “History of Science
and Technology”
UGC sponsored UGC
sponsored National Seminar
on “Recent Developments in
Green Chemistry”
UGC sponsored two day
National Seminar on “Recent
Development in Bio-Active
Molecules (RDBAM-2016)”
17th-18th Feb.,
2014
9th March, 2014
Areas of Interest
Synthetic Organic Chemistry, especially, radical cyclisation using a transition metal radical
source and related methodology. Wrote few Review Papers on Microwave Assisted Organic
Synthesis, Green Chemistry, Medicinal Usefulness of Vitex negundo Linn., Herbal Medicine
etc. Also wrote two text books on Practical Chemistry of Hons./Gen. Course and Practical
Chemistry of Engineering Course and published two edited volumes.
List of Publications
Books:
i.
Text Book on Undergraduate Chemistry Practical Courses, Dr. KK Rana, Bhasa
O Sahitya, Kolkata, (Dec., 2011), ISBN: 978-81-8438-054-2
ii.
Text Book on Chemistry Practical for Engineering Courses, Dr. KK Rana ad Dr. S
Rana, Bhasha o Sahitya, Kolkata, (Jan., 2015), ISBN: 978-81-8438-078-X
iii.
Proceedings of the Golden Jubilee (1965-2015) Celebration of Gushkara
Mahavidyalaya, Edited Volume, (Aug., 2015), ISBN: 978-93-5235-350-7
iv.
Proceedings of the UGC Sponsored National Seminar on “Recent Developments
in Green Chemistry”, Edited Volume, (Aug., 2015), ISBN: 978-93-5235-543-3
Papers:
1). “A Mild and Efficient Method for the Deoxygenation ofEpoxyketones to Enones.”
KK Rana and SC Roy; J. Ind. Chem. Soc., 1999, 76, 545.
2). “A Short and Stereoselective Total Synthesis of (±)-Sesamin by Radical Cyclisation of an
Epoxide Using a Transition Metal Radical Source.”
KK Rana, C Guin and SC Roy; Tetrahedron Lett., 2000, 41, 48, 9337.
3). “Ceric Ammonium Nitrate Mediated Selective Bromoalkoxylation of Activated Cinnamyl
Compounds Using Lithium Bromide.”
KK Rana, C Guin and SC Roy; Synlett, 2001, 2, 226.
4). “Synthesis of Spirocyclic Ethers by Radical Cyclisation of Epoxides Using a Transition
Metal Radical Source.”
KK Rana, C Guin and SC Roy; Ind. J. Chem., 2001, 40B, 925.
(Dedicated to Prof. UR Ghatak on the occasion of his 70 th birth anniversary)
5). “Short and Stereoselective Total Synthesis of (±)-Dihydrosesamin and (±)-Acuminatin
Methyl Ether by Radical Cyclisation of Epoxides Using a Transition Metal Radical Source.”
KK Rana, C Guin and SC Roy; Synlett, 2001, 8, 1249.
6). “An Efficient Chemo- and Regioselective Oxidative Nuclear Bromination of Activated
Aromatic Compounds Using Lithium Bromide and Ceric Ammonium Nitrate.”
SC Roy, C Guin, KK Rana and G Maiti; Tetrahedron Lett., 2001, 42, 6941.
7). “Stereoselective Synthesis of
Trisubstituted Tetrahydrofurans by Radical Cyclisation
Reaction Using a Hypophosphite Salt. Application to the Total Synthesis of (±)Dihydrosesamin.”
SC Roy, C Guin, KK Rana and G Maiti; Tetrahedron, 2002, 58, 2435.
8). “Short and Stereoselective Total Synthesis of Furano Lignans (±)-Dihydrosesamin, (±)Lariciresinol Dimethyl Ether, (±)-Acuminatin Methyl Ether, (±)-Sanshodiol Methyl Ether, (±)Lariciresinol, (±)-Acuminatin, (±)-Lariciresinol Monomethyl Ether and Furofuran Lignans (±)Sesamin, (±)-Eudesmin, (±)-Piperitol Methyl Ether, (±)-Pinoresinol, (±)-Piperitol, (±)-
Pinoresinol Monomethyl Ether by Radical Cyclisation of Epoxides Using a Transition Metal
Radical Source”
SC Roy, KK Rana and C Guin, J. Org. Chem., 2002, 67, 10, 3242.
9). “A Novel and Efficient Ceric Ammonium Nitrate Catalysed Oxidative Nuclear Chlorination
of Activated Aromatic Compounds by Acetyl Chloride.”
SC Roy, KK Rana, C Guin and B Banerjee, Synlett., 2003, 2, 221.
10). “A Mild and Efficient Method for the Protection of Carbonyl Compounds as Oxathiolanes,
Dithiolanes and Dithianes Catalyzed by Molybdenylacetylacetonate.”
KK Rana, C Guin, S Jana and SC Roy, Tetrahedron Lett., 2003, 44, 8597.
11). “Ceric Ammonium Nitrate Catalyzed Mild and Efficient -Chlorination of Ketones by
Acetyl Chloride.”
SC Roy, KK Rana, C Guin and B Banerjee, ARKIVOK, 2003, (ix), 34.
(Dedicated to Prof. Asima Chatterjee on the occasion of her 85th birth anniversary.)
12). Mild and Efficient Molecular Iodine Catalyzed Protection of Carbonyl Compounds as
Oxathiolane Derivatives.”
KK Rana, C Guin, B Banerjee and SC Roy, J. Ind. Chem. Soc., 2003, 80, 1005. (Dedicated
to Prof. SM Mukherjee.)
13). “A review on Indian Women Scientists”,
K.K. Rana and S. Rana, Communique (ISSN: 0973-8584), 2014, March, 8(1), 93-98.
14). “Review on Medicinal Usefulness of Vitex negundo Linn.”
S. Rana and K.K. Rana, Open Access Library Journal (ISSN: 1234-1010), 2014, 1(3),
1-13. http://dx.doi.org/10.4236/oalib.1100508
15). “Review on Present Status and Future of Herbal Medicine”,
K.K. Rana and S. Rana, The Beats of Natural Sciences (ISSN: 2348-7615),
2014(June), 1(2), 1-8.
16). “Fundamentals, Representative Applications and Future Perspectives of Green
Chemistry: A Short Review”
K.K. Rana and S. Rana, Open Access Library Journal (ISSN: 1234-1010) 2014, 1(5),
1-16. http://dx.doi.org/10.4236/oalib.1100748
17). “Microwave Reactors: A Brief Review on Its Fundamental Aspects and Applications”
K.K. Rana and S. Rana, Open Access Library Journal (ISSN: 1234-1010) 2014, 1(6), 1-20,
http://dx.doi.org/10.4236/oalib.1100686
Paper wise Syllabus Taught
UG HONOURS COURSE
BSc Part-I Chemistry (Hons.)
Paper II
Full Marks: 50
ORGANIC CHEMISTRY (THEORY)
1. General introduction (4 lectures) Nomenclature of organic molecules with special
reference to polycyclic, bridge head, aromatic, heteroaromatic and heterocycles compounds,
molecular weight (preliminary idea about mass spectroscopy), molecular formula
2. Structure and properties (8 lectures) Nature of bonding in aliphatic, alicyclic, aromatic
and heterocyclic compounds; bond length, bond strength, bond angle and their variations in
compounds with sp3, sp2 and sp hybridized carbon atoms; orbital pictures of methane,
ethane, ethene, ethyne, allene and benzyne; delocalised bonds, resonance, steric inhibition
of resonance, hyperconjugation, tautomerism, aromaticity, Huckel’s rules, aromatic,
nonaromatic and antiaromatic compounds, non-benzenoid aromatic compounds, Huckel’s
rule Inductive and field effects; dipole moment, H-bonding and its effect on physical and
chemical properties of organic molecules
3. Introduction to organic reactions (7 lectures) Homolysis and heterolysis of bonds;
types of reactions: ionic, radical and pericyclic; Bronsted-Lowry concept, Lewis concept,
strengths of acids and bases; effect of solvent on acidity and basicity; relationship between
structure and acidity and basicity, acid-base reactions Thermodynamics and kinetics of
organic reactions, energy profiles for one-step and two- step reactions, catalyzed reactions,
Hammond postulate, principle of microscopic reversibility, kinetically and thermodynamically
controlled reactions; methods of determination of organic reactions: study of intermediates,
kinetic and stereochemical studies, non-kinetic and kinetic studies with isotopes (primary and
secondary kinetic isotope effects), crossover experiments
4. Reactive intermediates (8 lectures) Formation, structure, stability and reactions of
classical and non-classical carbocations, carbanions, free radicals, arynes, ylides, carbenes
and nitrenes
5. Stereochemistry (20 lectures) Concept of constitution, stereochemical representation:
Fischer, Newman, Sawhorse, Flying-wedge and their interconversions, molecular symmetry:
plane, centre, simple and alternating axes; symmetry operations, chirality and chiral centre,
configuration, configurational nomenclature: D/L, R/S, erythro/threo; optical activity and
optical isomerism, optical rotation: specific and molecular; optical purity, enantiomeric
excess; resolution of optical isomers; chiral axis in allenes, biphenyls and spiranes and their
R/S descriptors Geometrical isomerism (diastereomerism) of molecules with C=C, C=N
(oximes) and simple cyclic molecules; cis/trans and E/Z nomenclature Conformation of
alkanes and cycloalkanes: dihedral angle and angle of torsion, gauche, eclipsed and
staggered arrangements; synperiplanar, synclinal, anticlinal, antiperiplanar conformations;
conformation-energy diagram of ethane, propane and n-butane, relative stability of
conformers on the basis of steric effect, dipole-dipole interaction, H-bonding; conformational
analysis of cyclohexane and its mono- and di-substituted derivatives with chair, boat and
twist boat forms and their symmetry properties and optical activity; strains in molecules:
angle, bond, torsional and steric; steric and stereoelectronic factors.
6. Aliphatic nucleophilic substitution reactions (8 lectures) Free radical and nucleophilic
substitutions at sp3 carbon: SN1, SN2, SNi SN1′, SN2′, SNi′ reactions; NGP Factors affecting
rates of SN1 and SN2 reactions, phase transfer catalyst and its use in organic reaction, use of
crown ether in substitution reaction; functional group transformations using S N2 reactions
7. Elimination reactions (5 lectures) E1, E2 and E1CB mechanisms, reactivity,
Saytzeff/Hofmann orientation and stereoselectivity; elimination Vs substitution; syneliminations: pyrolysis of ester, xynthate, tert-N-oxide.
BSc Part-I Chemistry (Hons.)
Paper IV
Full Marks: 50
ORGANIC CHEMISTRY (PRACTICAL)
Organic Qualitative analysis (30 marks)
Recording of physical characteristics (colour, texture, odour and melting point)
Preliminary tests (ignition test, soda lime test, litmus test, unsaturation test, Beilstein test)
Lassaigne’s test (detection of special elements N, S, halogens)
Solubility classification (H2O, 5% HCl, 5% NaOH, 5% NaHCO3, conc. H2SO4, conclusion)
To be recorded in a tabular form)
Functional group detection [Nitrogen containing: aromatic -NH2 and -NO2, -CONH2, CONHAr; non-nitrogenous: phenolic -OH, -COOH, -CO- (aldehydic or ketonic), -CO2R]
Literature survey (selection of suitable derivative)
Derivative preparation (procedure and recording of melting point)
Conclusion
Organic preparation (10 marks)
(A) Condensation: preparation of phthalimide
(B) Nitration: nitration of nitrobenzene, acetanilide
(C) Oxidation: oxidation of benzyl chloride/benzyl alcohol, benzoin
(D) Acetylation: acetylation of aniline using glacial acetic acid
(E) Hydrolysis: hydrolysis of amide/imide, esters
(F) Bromination: bromination of acetanilide using KBr, KBrO3 and glacial acetic acid
LNB (5 marks)
Viva-voce (5 marks)
BSc Part-II Chemistry (Hons.)
Paper VI
Full Marks: 50
ORGANIC CHEMISTRY (THEORY)
1. Stereochemistry (4 lectures) Stereogenecity, chirotopicity, achirotopicity, prochirality,
topicity of ligands and faces (Pro-R, Pro-S and Re/Si designations), chemoselective,
regioselective, steroselective: diasteroselective, enantioselective reactions with examples.
Asymmetric synthesis: Cram’s rule
2. Electrophilic and radical addition to C-C multiple bonds (4 lectures) Halogenation,
hydrohalogenation, hydration, hydrogenation, epoxidation, hydroxylation, ozonolysis, 1,3dipolar additions; electrophiilic addition to conjugated dienes and allenes; radical addition
addition of HBr; reduction of alkynes and bezenoid aromatics Diels-Alder reaction, addition of
carbenes
3. Nucleophilic addition to carbonyl group (10 lectures) Reactions with water, alcohols,
amines, thiols, HCN, bisulfite, Wittig reaction, Meerwein-Pondorf- Varley reduction, reduction
with
lithium
aluminum
hydride
and
sodium
borohydride,
Wolff-Kishner
reduction,
Clemmensen reduction, Bouveault-Blanc reduction, addition of organometallics, addition of
diazomethane, Cannizzaro reaction, aldol condensation including directed aldol reaction,
Claisen condensation, Knoevenagel reaction, Stobbe reaction, Reformatsky reaction,
Mannich reaction, Darzen’s glycidic ester synthesis, Perkin reaction, benzoin condensation,
Dieckman reaction, acyloin condensation, nucleophilic addition (Michael addition) to α,βunsaturated carbonyl system
4. Molecular rearrangement (5 lectures) Wagner-Meerwein, Pinacol-Pinacolone, Dakin,
Bayer-Villiger, Beckmann, Favorasky, Hoffmann, Lossen, Schmidt, Curtius, benzil-benzillic
acid, dienone-phenol, Wolf, Claisen, Fries, Photo Fries, Orton, Demjanov, benzidinesemidine
5. Reagents in organic synthesis (6 lectures) Grignard, alkyl lithium, LDA, LiAlH4, B2H6,
Me3SiCl, R2CuLi, Wilkinson catalyst, NaBH4, DIBAL-H, 1,3-dithiane, OsO4, KMnO4
6. Named reactions (6 lectures) Birch, von Richter, Houben-Hoesch, Arndt-Eistert
homologation, Hell-Volhard-Zelinsky, Hunsdiecker, Oppenauer, Sandmeyer, Stephen,
Williamson ether synthesis
7. Alicyclic compounds (6 lectures) Structure of simple alicyclic compounds upto sixmembered ring; strain theory in classical and modern theoretical approach, ease of ring
formation; physical properties with respect to dipole moment and acid strengths (cyclohexane
system
only)
Synthesis
and
reactions
in
cyclohexane
systems:
E2
elimination,
rearrangement, SN1 and SN2 including NGP, oxidation of cyclohexanols
8. Synthesis, physical properties and reactions (6 lectures) (i) Aliphatic and aromatic
nitrogen compounds: amines, nitro compounds, nitroalkanes, alkyl nitriles, aromatic
diazonium compounds, diazomethane; (ii) nitrophenols, aminophenols, nitroanilines, amino
carboxylic acids9
9. Aromatic electrophilic substitution (8 lectures) Mechanism, orientation and reactivity;
nitration,
nitrosation,
sulfonation,
halogenation,
Friedel-Crafts,
Haworth
synthesis,
Gatterman-Koch, Gatterman, Hoesch, Vilsmeier-Haack, Reimer-Tiemann, Kolbe-Schmidt,
chloromethylation, Manasse, Kolbe
10. Aromatic nucleophilic substitution (5 lectures) Addition-elimination mechanism,
ArSN1 mechanism, elimination-addition (benzyne) mechanism; orientation and reactivity.
BSc Part-III Chemistry (Hons.)
Paper X
Full Marks: 100
ORGANIC CHEMISTRY (THEORY)
Group A
1. Dyes (3 lectures) Phenolphthalein, methyl orange, malachite green, alizarin
2. Medicinal chemistry (5 lectures) Preliminary concept on pharmacodynamics and
pharmacokinetics; syntheses and uses of paracetamol (antipyretic), aspirin and phenacetin
(analgesics), sulphanilamide and sulphaguanidine (sulpha-drugs), chloroquine (antimalarial)
3. Heterocyclic compounds (16 lectures) Syntheses, properties and uses of furan, pyrrole,
thiophene, pyridine, quinoline, isoquinoline and indole
4. Amino acids and proteins (14 lectures) Essential and non-essential amino acids,
isoelectric point, ninhydrin reaction, synthesis of glycine, alanine and tryptophan;
classification of proteins, geometry of peptide linkage, elementary idea about primary and
secondary structures of proteins; C-terminal, N-terminal and their determination; peptide
synthesis, Merrifield synthesis
5. Carbohydrate chemistry (11 lectures) Chemistry of monosaccharides and disaccharides
including structures and configurations: D-glucose, fructose, galactose, arabinose and
sucrose; stepping-up and stepping-down of monosaccharides, conversion of aldose to ketose
and vice versa; mutarotation, epimerization, anomeric effect, elementary idea about starch
and cellulose
6. Alkaloids and terpenenoids (11 lectures) General studies of terpenenoids and alkaloids;
biosynthesis of terpenes; determination of structures of citral, nerol, α-terpineol, piperin,
ephedrine and coniine
Group B
7. Methodology in organic synthesis (15 lectures) Disconnection approach, synthon,
synthetic equivalents, umpolung, one-group disconnection of alcohols, olefins and ketones;
synthesis involving enolates and enamines with special reference to diethyl malonate and
ethyl acetoacetate; two-group disconnections for dioxygenated molecules (1,2-; 1,3-; 1,4-;
1,5- and 1,6-systems), Robinson annelation; reconnection; synthesis through protection of
functional groups
8. Pericyclic reactions (16 lectures) FMO approach, definition, classification, electrocyclic
reactions (including Woodward-Hofmann selection rules): [4+2] cycloaddition with special
reference to Diels-Alder reaction, alder ene reaction, [2+2] cycloaddition; sigmatropic
reactions: [1,j] and [i,j] shifts, [1,3] and [1,5] H-shifts, [3,3] sigmatropic shifts with reference to
Cope and Claisen rearrangements
9. Spectroscopy (20 lectures) UV: Electronic transitions with reference to σ-σ*, n-σ*, π-π*,
n-π* transitions; absorption maximum and absorption intensity, effect of solvent; Woodward
rule with reference to conjugated system like dienes, trienes and α,β-unsaturated carbonyls
including cyclic systems IR: Hooke’s law, stretching and bending vibrations, characteristic
and diagnostic stretching frequencies, factors affecting stretching frequencies (H-bonding,
electronic factor, ring size), finger-print region, diagnostic bending frequencies for benzene
and its o-, m- and p-isomers 1H NMR: Principle, nuclear spin, NMR-active nuclei, chemically
equivalent and nonequivalent protons; chemical shift, upfield and downfield shifts;
shielding/deshielding of protons in systems involving C-C, C=O, C=C, benzene, cyclohexane;
spin-spin splitting with reference to CH3CH2Br, CH3CH2OH, Br2CHCH2Br; characteristic 1H
NMR signals for simple molecules Application of the above spectroscopic methods in
structure elucidation of simple organic molecules
10. Nucleic acids (4 lectures) Heterocyclic bases, nucleosides, modified nucleosides,
nucleotides; idea about DNA and RNA
11. Green chemistry (5 lectures) Principles, starting materials, reagents, solvents,
catalysts, utilities.
UG GENERAL COURSE / PASS COURSE
BSc Part-I Chemistry (Gen.)
Paper I
Full Marks: 100
ORGANIC CHEMISTRY (THEORY)
Group B Organic Chemistry (Full Marks: 50)
1. Functional Nature of Organic Compounds Classification of organic compounds in terms
functional groups, their IUPAC nomenclature and valence bond structures.
2. Electron Displacement in Molecules Concept of Inductive effect, Electromeric effect,
Hyperconjugation, Resonance, Aromaticity and Tautomerism.
3. Introduction to Organic Reaction Mechanism Homolytic and heterolytic bond cleavage;
Reaction intermediates: carbocation, carbanion, free radical. Classification of organic
reactions (substitution, elimination, addition and rearrangement) and reagent types
(electrophiles, nucleophiles, acids and bases), Ideas of organic reaction mechanism (SN1,
SN2, E1 and E2).
4. Chemistry of Hydrocarbons a) Free radical substitutions of alkanes; b) Formation of
alkenes, electrophilic addition reactions of alkenes (upto four carbon atoms), Markwonikoff’s
rule, peroxide effect, ozonolysis, radical addition and catalytic reductions; c) Formation of
alkynes, their partial and complete reductions and hydration. Halogen derivatives of alkanes,
their nucleophilic substitutions and elimination reactions.
5. Mono and Bifunctional Compounds Preparations and properties of primary, secondary
and tertiary monohydric alcohols, ethers, ethylene glycol, pinacol and glycerol; aldehydes
and ketones; monocarboxylic acids and their derivatives: acid chlorides, anhydrides, esters,
amides; amines; unsaturated alcohol (allyl alcohol), unsaturated aldehyde (acrolein),
unsaturated carboxylic acid (acrylic acid), unsaturated ester (methyl acrylate), di- and tribasic
acids (oxalic, malonic, succinic acids; malic and citric acids).
6. Stereochemistry Concept of optical activity, optical properties of lactic acid and tartaric
acid, D,L and R,S nomenclature; Geometrical isomerism with reference to fumaric acid and
maleic acid; cis-trans and E, Z nomenclature.
7. Chemistry of Aromatic Compounds Modern concept of structure of benzene, general
mechanism of aromatic electrophilic substitution reactions, preparations and properties of
toluene, xylene, halobenzenes, benzyl chloride, benzoyl chloride, benzotrichloride,
nitrobenzene, dinitrobenzene, TNT, aniline, methyl and dimethyl aniline, benzyl amine
benzene diazonium chloride, phenols, benzyl alcohol, benzaldehyde, acetophenone, benzoic
acid, anhydride, amides, esters; phenyl acetic acid, salicylic acid, cinnamic acid, sulphanilic
acid, phenyl hydrazine, nitrophenols and picric acid.
8. Organic Synthesis Preparation and synthetic uses of diethyl malonate and
ethylacetoacetate. Application of Grignard reagents in synthesis of ketones, secondary and
tertiary alcohols and carboxylic acids.
9. Carbohydrates Open-chain and ring structures glucose, fructose and their mutarotation,
idea of dissacharides with reference to cane sugar.
BSc Part-III Chemistry (Gen.)
Paper IV
Full Marks: 65
ORGANIC CHEMISTRY (THEORY)
1. Chemistry of Selected Biomolecules Structural aspects (excluding elucidation and
stereochemistry, unless specified) and important function of d/l-sucrose and polysaccarides
(starch and cellulose), amino acids (classification, essential amino acids like glycine, alanine,
methionine and tryptophan with d/l), proteins (special reference to the peptide bond, action of
haemoglobin, idea of denaturation of proteins, classification and functions of enzymes in
general), pyrrole, pyridine, pyrimidine and purine, nucleic acids (DNA and RNA), nucleotide
and nucleoside.
2. Medicinal Chemistry Antipyretics and analgesics like paracetamol and aspirin, sulphadrugs like sulphadiazine, antibiotics like penicillin and chloramphenicol,ofloxacin; antiamoebic
like metronidazole, anticancer drugs, drugs used for AIDS (detailed structures are not
needed, only the nature and function of the drugs).
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