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Sexuality and End Stage Renal Disease
(ESRD)
UHN
Information for patients and families
Read this information to learn:
• how ESRD can cause changes in sexuality
• what changes can happen in men and women
• what treatments are available
• who to talk to if you have any questions
How can ESRD affect my sex life?
End Stage Renal Disease (ESRD) is complete or almost complete failure of the
kidneys. ESRD causes many changes to your body. This affects many areas of your
life, including how you experience sex.
ESRD can cause changes to:
• your ability to perform and enjoy sex (also called sexual dysfunction)
• your sexuality
Sexuality means more than performing sex. It also includes how you:
• feel about yourself
• share your feelings with others
• build relationships
Please visit the UHN Patient Education website for more health information: www.uhnpatienteducation.ca
© 2013 University Health Network. All rights reserved.
This information is to be used for informational purposes only and is not intended as a substitute for professional
medical advice, diagnosis or treatment. Please consult your health care provider for advice about a specific
medical condition. A single copy of these materials may be reprinted for non-commercial personal use only.
Author: The Hemodialysis Team
Created: 05/2006
Form: D-5343 (02/2014)
What kinds of changes to sexuality can ESRD cause?
Changes that may happen to men with ESRD include:
• less desire for sex
• difficulty ejaculating
• difficulty getting or keeping an erection
• low self-esteem
Changes that may happen to women with ESRD include:
• less desire for sex
• painful intercourse
• changes in menstrual cycles
• low self-esteem
Women with ESRD can get pregnant. It is important to use some type of birth
control. Talk to your healthcare team, if you are thinking of getting pregnant.
How does ESRD cause sexual dysfunction?
ESRD can cause sexual dysfunction in different ways.
1. Physical Causes
• Hormone imbalances
ESRD can cause men’s hormone levels to change. The hormones
testosterone, estrogen and prolactin can be out of balance. This can
reduce libido (desire for sex) and cause difficulty with erections.
Changes in hormones for women can cause painful intercourse. It can
also cause changes to how they ovulate or menstruate.
2
• Blood vessel damage
High blood pressure and diabetes can cause damage to blood vessels. A
build-up of waste products (called Uremia) also damages blood vessels.
Blood vessel damage may cause men to have trouble getting an erection
(also called erectile dysfunction).
• Decreased sensation
Uremia and diabetes can cause nerve damage (nerve numbness). This
can lead to erectile dysfunction. It can also cause men to take longer to
ejaculate (also called delayed ejaculation).
2. Medication side-effects
Some prescription medications can cause loss of libido, erectile dysfunction
and delayed ejaculation. Recreational drugs (for example: marijuana,
cocaine and crack) can also cause sexual dysfunction.
3. Life changes
People with ESRD experience many changes in their lives. These may
include:
• financial problems because you are unable to work
• less travel and social activities
• decreased ability to enjoy your hobbies
• low self-esteem because of your medical condition
Please remember:
Sexual problems are common for people with ESRD. Some treatments are
available. Talk to your nurse, social worker or nephrologist about any concerns
you may have. Please feel free to let your health care worker know if you need
somewhere quiet or private to talk.
3
What treatments are available?
There are treatments for some causes of sexual dysfunction. Your nurse or
nephrologist can help you decide on treatment.
Here is a list of some options:
• Hormone therapy
A medication with hormones is prescribed to increase or replace hormones
lost because of ESRD.
• Medications
Medications like Sildenafil (Viagra®) are prescribed to help men with
erectile dysfunction.
Don't take Viagra if you take nitrates (often prescribed for chest pain)
because this may cause a sudden, unsafe drop in blood pressure.
• Penile implant surgery
Men who are suitable for this surgery have a material put into their penis to
help keep it erect (hard) during sex.
• Penile injection
A medication is injected into the penis to produce an erection.
• External suction
A suction pump is placed over the penis to help produce an erection.
• Sexual counselling
Both men and women can benefit from talking to a sex therapist. A sex
therapist can help men and women manage their difficulties with sex.
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Who can I talk to if I have questions?
Talk to your nurse, social worker or nephrologist if you have any questions. They
can listen if you would like to talk more about your sexuality.
Original document prepared by:
Denise Williams, RN, MN, CNeph(c)
Soh Tee Goh, RN, BScN
Deloris Bennett, RN, BScN, CNeph(c)
Edited by: Vanessa Godfrey, RN, MScN, CNeph(c), February 2014
Reviewed by:
Hemoquality Committee, Patient Education Sub-Committee
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