Download AND EAR INFIRMARY

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symposia & events 2016
February 20-26, 2016
9th Annual Illinois Eye Review
Friday, April 22, 2016
9th Annual Retina Symposium
Wednesday, May 25, 2016
2016 Spring Glaucoma Symposium
Friday, June 17, 2016
40th Annual Alumni / Resident Day
Sunday, October 16, 2016
Alumni Reception at the AAO Meeting
Saturday, October 22, 2016
The Chicago Chronic GVHD Meeting
http://eyecare.uic.edu l www.chicago.medicine.uic.edu/eye
Proud Community Partner
ONE VISION2014-15
Department of Ophthalmology and Visual Sciences
Illinois Eye and Ear Infirmary
University of Illinois College of Medicine
AND EAR INFIRMARY
IN THIS ISSUE
1
2
4
6
8
10 28 32 34 36 38 40 48 49 Leadership
Shedding Light on the “Bionic Eye”
Artificial Cornea Program Flourishes
PROSE Clinic Makes Strides
Stem Cells and Sight
Clinical Services/Faculty
Research Faculty
Sponsored Research
Clinical Investigations and Trials
Giving
Education
Publications
In Memoriam; Investiture
Cless Lab
LEADERSHIP
Mark I. Rosenblatt, MD, PhD, MBA | Professor and Department Head
Lions of Illinois/Charles I. Young Chair in Ocular Research
Joel Sugar, MD | Vice Chair for Clinical Operations
Joel Sugar MD Professor in Ophthalmology
William F. Mieler, MD, FARVO | Vice Chair for Education
Cless Family Professor in Ophthalmology
Mahnaz Shahidi, PhD | Vice Chair for Research
Morton F. Goldberg MD FACS Professor in Ophthalmology
CLESS FAMILY OPHTHALMIC SURGICAL TRAINING
AND SIMULATION CENTER
Timothy McMahon, OD, FAAO | Vice Chair for Optometry
Professor of Ophthalmology
R. V. Paul Chan, MD, FACS | Vice Chair for Global Ophthalmology
Professor of Ophthalmology
The Illinois Eye and Ear Infirmary is known as a leader in the field of ophthalmic training in the region and in the
nation. One component of this leadership is providing the highest level of surgical training that is available. This
year we inaugurated the 9 station state-of-the-art Cless Family Ophthalmic Surgical Training and Simulation
Center (Cless Lab), the premier center for ophthalmic surgical training in the Midwest. The Cless Lab will be
home to surgical training courses, webcasting and live surgery streaming as well as surgical simulation technology. A generous investment made by the Cless Family Foundation, along with support from faculty and alumni,
made this vision a reality. Establishing the Cless Lab is an enormous advancement in how we train our residents
and surgical fellows. It is an active learning environment allowing for a virtual-reality simulation experience within
which attention to the finest, most minute details, such as the careful orchestration of hand and foot instrument
manipulation, can be perfected without putting patients at risk. It will no doubt significantly increase trainees’
aptitude and confidence when performing in a live operating room.
The virtual connections this equipment makes possible will enable us to examine how fellow surgeons from all
corners of the world do work, and repeat it right here. This exposure to new information and practices will fuel
the innovation and breakthroughs that will happen here first. And, when they do, we can share them with the rest
of the world right from the Cless Lab. We now are able to provide services few places in the world can offer. Our
faculty, residents, fellows, alumni and local ophthalmologists can learn more, innovate faster and pioneer surgical
curriculum because of these connections.
CREDITS
Writers
Lisa Holton
Margaret Doyle
Editor
Laurie Walker
Designer
Lisa Birmingham
Contributors
Margaret Chervinko, Lauren Hughes,
Cristina Lee, Kristen Scheurich,
Laurie Walker
Photography
Cathy Carroll, Joshua Clark,
Roberta Dupuis-Devlin,
Mark Janowicz
On the cover
Visionary by Gwyn Newcombe
Left to right: Drs. Sugar, McMahon, Shahidi, Mieler and Rosenblatt—not pictured, Dr. Chan
A MESSAGE FROM THE DEPARTMENT HEAD
I am deeply honored to serve as the Head of the Department of Ophthalmology and
Visual Sciences at the Illinois Eye and Ear Infirmary/University of Illinois College of
Medicine.
The Department has a historic legacy of unparalleled clinical care, outstanding education,
and innovative research. This could not have been done without the combined efforts of
our faculty, staff and supporters. For over 155 years, the Infirmary has been leading the
way in advanced care for patients who have some of the most serious and complicated
eye conditions. The subspecialty services and clinicians in the Department are nationally
known for providing this care. We all share in this invaluable commitment to treating and
curing eye diseases such as cataracts, glaucoma, and age-related macular degeneration.
Ophthalmologic innovation is happening here.
The modern healthcare landscape and the rapid development of new technologies
present us with a unique opportunity to foster innovation and pursue new connections
between medicine and engineering to address complex ophthalmic conditions. We are
pursuing the development of new fellowship opportunities, including ones in global
ophthalmology, which will allow us to inspire innovation here at home and impact
patients and clinical care around the globe. Our scientific discoveries will influence how
we treat the most serious and complicated eye conditions, and enhance the quality of
life for our patients.
Our Illinois Eye and Ear Infirmary (IEEI) residents and trainees have shaped our department, programs and clinics. Their commitment to innovative, inspired and impassioned
medicine has helped to establish IEEI as a national center for excellence in resident
education. We are proud to train the best and brightest in ophthalmology and we are
excited to roll out a brand new surgical curriculum for our trainees in 2016 that corresponds with our new state-of-the-art Cless Family Ophthalmic Surgical Training and
Simulation Center.
Innovative medicine is happening now.
In the Department of Ophthalmology and Visual Sciences, we are pioneering innovation
in three important areas: high-resolution functional imaging, nanoscale device development and tissue engineering to help us better diagnose and treat eye disease earlier, and
preserve the sight of our patients.
Mark I. Rosenblatt, MD, PhD, MBA
Professor and Head
Department of Ophthalmology & Visual Sciences
Lions of Illinois /Charles I. Young Chair in Ocular Research
Director, Corneal Regenerative Medicine Laboratory
Medical School
University of Miami (PhD, Biochemistry)
Residency in Ophthalmology
Massachusetts Eye and Ear Infirmary
Clinical Fellowship
Massachusetts Eye and Ear Infirmary (Cornea)
Research Fellowship
Schepens Eye Research Institute
Graduate School
New York University (MBA)
In order to continue to lead and stay in sync with advances in medicine, science and
technology, we have established an exciting partnership with the University of Illinois
College of Engineering at Urbana-Champaign. This partnership will support joint conferences, train physicians and scientists, and collaborate between departments to develop
solutions for sight-threatening diseases. Our intentional convergence of medicine and
engineering will greatly improve ophthalmic conditions around the world.
Our new Ophthalmology Clinical Trials Center underscores our commitment to medical
research, which has contributed to advances in Ophthalmology and related areas of
medicine. These fundamental discoveries impact our academic medical program and
allow us to provide quality eye care to those in need.
We offer our gratitude to our friends and supporters and invite you all to join us on this
journey for ongoing innovation, productivity and discovery.
OneVision | 1
SHEDDING LIGHT ON THE “BIONIC EYE”
The University of Illinois’ Argus II trial moves ahead, returning sight to the blind.
The Argus II® retinal prosthesis system – also known as
the “Bionic Eye” trial – has been making news at the Illinois
Eye and Ear Infirmary’s (IEEI) Department of Ophthalmology since manufacturer Second Sight named the IEEI one
of 13 North American clinical testing sites after getting
FDA approval in 2013.
planted with an electronic device and that the vision will
not be ‘normal vision,’” she explained. At this time, the device does not allow for enough resolution to see faces or
colors. However, for many patients, the added visual information provided by Argus II can improve the patient’s
ability to navigate paths, find doorways and “see people
moving about,” returning a significant degree of visual independence to their lives. Additionally, given advances in
engineering which allows technology to become smaller
and more powerful over time, vision outcomes, comfort
and other features of the bionic eye project will improve.
“It’s the chance to give some sight back to patients blind
from retinitis pigmentosa. Right now, there is no other way
you can return vision to completely blind patients,” explains
project leader Jennifer I. Lim, MD. The Argus II system
is designed to restore limited sight to individuals suffering
from retinitis pigmentosa, a genetic disease that causes
“Today, depending on how severely impaired a patient’s
progressive blindness by destroying the light-sensing cells
vision is, a patient might be able to see a white line that
in the retina. Eventually, this artificial
can help them walk independently
retina system may help tackle other
or be able to sort clothing into light
sight-destroying diseases like macuand dark colors,” Lim explains. Fular degeneration.
ture upgrades to the Argus system
“A lot of the most common
– named for the all-seeing giant
The University of Illinois Hospital &
procedures you see today
of Greek mythology – might not
Health Sciences System is the only
only eliminate the current required
were in clinical trials at the
medical center in Illinois selected to
bulky headgear of dark glassoffer the artificial retina. Lim says
IEEI including the first clinical
es and head-mounted camera
the success of the device – a surbut also provide the possibility of
trials for diabetic retinopathy,
gically implanted chip on the retina
sharper images.
that wirelessly receives informamacular degeneration, vein
tion from a head-mounted camera
Lim has worked with the inventor
occlusion and sickle cell
to help blind individuals “see” light
of the device, Mark S. Humayun,
and shapes in black and white – deMD, PhD, the biomedical engineer
management.
pends on the patient’s motivation
and retina physician who develand willingness to undergo “visual
oped the bionic eye at the Univertraining after implantation” to learn
sity of Southern California. She
how to use the device.
points out that such collaborative relationships are common at the Department of Ophthalmology.
The device uses an electrode array that goes directly onto
the patient’s retina. The electronic chip is connected to a
“The Department has always been a place of innovation,”
silicone strip that holds a receiver and is mounted to the
said Lim. “A lot of the most common procedures you see
outside of the eye. There is no discomfort and the current
today were in clinical trials at the IEEI including the first
technology is still in the early phase, Lim adds. “It’s not
clinical trials for diabetic retinopathy, macular degeneraright for everyone” suffering from RP, Lim explains. “A pation, vein occlusion and sickle cell management. We are
tient has to be comfortable knowing that they will be imjust in the early stages with this implant,” she said.
2
Argus® II illustration courtesy
of Second Sight Medical
Products, Inc.
“It’s the chance to give some sight back to patients blind from retinitis pigmentosa. Right now,
there is no other way you can return vision to completely blind patients,” explains project leader
Jennifer I. Lim, MD.
OneVision | 3
ARTIFICIAL CORNEA PROGRAM FLOURISHES
It takes a particular kind of patient to assure success, but the Department of Ophthalmology’s
work with the toughest cases has made it the Midwestern leader in artificial cornea
transplantation.
For over 150 years, the Department of Ophthalmology and
Visual Sciences at the Illinois Eye and Ear Infirmary (IEEI)
has provided the field of ophthalmology with a long list of
firsts in research, surgical technique and groundbreaking
patient care.
ease and we have formed a team of specialists to provide
them with the most comprehensive care possible. At the
IEEI we have incorporated cornea, glaucoma, vitreoretinal, oculoplastics, contact lens and uveitis specialists into
the artificial cornea team resulting in an interdisciplinary
approach” said Cortina, Director of the Artificial Cornea
Program at the University of Illinois College of Medicine.
Henry Winters knows this personally. Winters’ life changed
on Jan. 5, 1978 when he suffered chemical burns over
60 percent of his body at the manufacturing plant where
The Department has
he worked as a supervisor. “I got
hurt at 27 years of age, and I was
in suspended animation from that
day,” said Winters, who was comAs the work of the Artificial
pletely blind for three years before
receiving his first of several transCornea Program continues,
planted natural corneas starting in
patients like Winters illustrate
the 1980s.
one of the largest artificial cornea
programs in the country with a
strong research team to complement the large clinical program.
Our goal is to advance the field of
artificial cornea and we have made
significant contributions including
improvement of surgical outcomes
using high resolution imaging to
evaluate the formation of damagthe Department’s unique
Unable to work or drive from the
ing membranes behind the Kpro
approach to the toughest
day of the accident, Winters got
device and studying the formation
minimal and temporary improveof potentially dangerous microbial
cases in eye medicine.
ment from those transplants and in
biofilms on the device. Additionally,
recent years, he noticed again that
our engineering and basic science
the remaining vision in his left eye
team lead by Drs. Yu and Rosenblatt is investigating new
began to worsen. He and his wife started to look for other
materials and designs for a novel Keratoprosthesis device.
options, and in 2012, Winters and his doctor M. Soledad
Cortina started discussing the transplantation of the arCortina and fellow faculty member Jose de la Cruz have
tificial cornea known as the Boston Keratoprostheses, or
published a seminal first textbook on KPro technology and
KPro. KPro is now considered a surgical option for patients
transplant. The team gathered the latest and most comprewith poor prognosis for standard corneal transplants or
hensive knowledge and best practices on the device from
whose corneal transplants have failed. Later in 2012, Winleading specialists around the world and published “Kerters was implanted with a Boston Type 1 KPro. After more
atoprostheses and Artificial Corneas: Fundamentals and
than 30 years, he finally saw clearly from his less-injured
Surgical Applications” late in 2014. Says Cortina: “Much of
left eye.
what you will find in the book goes beyond current literature to experiences that have not been shared anywhere
“It was so exciting – it was the first time out of all those
else. All aspects of KPro surgery, from history and preopyears that I got a chance to see me,” Winters explained. “I
erative evaluation to surgical techniques and postoperacould go places, see places and I could read. When you
tive management of complications, are addressed by more
start seeing the words again after you’ve heard them all
than two dozen leading surgeons as chapter authors in the
that time, they don’t feel the same. I was finally able to get
first edition.
familiar again with what I saw.”
As the work of the Artificial Cornea Program continues,
Now 65, Winters is retired and has elected not to try to
patients like Winters illustrate the Department’s unique
drive. But seeing again reminded him how withdrawn he
approach to the toughest cases in eye medicine. “Our
was for so much of his life.
patients come to us with a variety of visual and physical
challenges that few treatment centers see,” said Cortina.
“The Department of Ophthalmology at the IEEI has a par“We believe that our interdisciplinary approach allows us to
ticular and unique approach to the artificial cornea. We untransform the lives of some of our sickest patients.”
derstand that these patients suffer from complex eye dis-
4
“It was so exciting – it was the first time out of all
those years that I got a chance to see me,” Winters
explained. “I could go places, see places and I
could read...I was finally able to get familiar again
with what I saw.”
Front Part
Corneal Graft
Back Plate
Front Part
Corneal Graft
Back Plate
OneVision | 5
PROSE CLINIC MAKES STRIDES
New prosthetic solutions help patients regain sight, mobility and independence
PROSE (short for Prosthetic Replacement of the Ocular Surface Ecosystem) is a device and
treatment system that aims to restore vision, promote healing and improve the quality of life
for patients with complex corneal disease.
6
When Dr. Ellen Shorter, OD, FAAO joined the Department
of Ophthalmology and Visual Sciences at the Illinois Eye
and Ear Infirmary (IEEI), one of her first objectives was
to complete the intensive BostonSight® PROSE Clinical
Fellowship.
Rapaport conferred with her doctors at Milwaukee’s Eye
Institute and mentioned she had heard about PROSE.
They referred her to the Department’s PROSE Clinic and
after her first visit to Chicago in January 2014 she planned
to began treatment that summer.
Pioneered at the Boston Foundation for Sight, PROSE
(short for Prosthetic Replacement of the Ocular Surface
Ecosystem) is a device and treatment system that aims to
restore vision, promote healing and improve the quality of
life for patients with complex corneal disease.
PROSE prosthetics are thin transparent devices made of
gas-permeable plastic that allow oxygen and a healing saline solution to reach the ocular surface. The device fits
under the eyelid and rests on the sclera (the white tissue
of the eye), vaulting the cornea, and creating a reservoir of
saline solution that continuously bathes the diseased eye
in oxygenated artificial tears. The result is a new, smooth
optical surface.
In 2010 the IEEI opened its PROSE Clinic, one of only 12
in the United States, with Shorter as
its first director.
“Most of our patients have severe
ocular surface disease or advanced
corneal ectasia,” Shorter explains.
“Many of our patients have been to
multiple eye doctors and are frustrated. PROSE treatment is a final
option when other standard therapies have failed.”
Even better, Rapaport said
she can now clearly see her
newborn grandchild. “It’s just
been phenomenal.”
For many patients, PROSE may be
the ideal and sometimes only treatment that can restore
vision and dramatically reduce eye pain and light sensitivity. PROSE offers hope to patients with conditions such
as Stevens-Johnson syndrome (SJS), severe dry eye syndrome, Sjogren’s syndrome, keratoconus, pellucid marginal degeneration (PMD), ocular trauma and post-transplant
or LASIK complications.
For example, Shorter notes that several of her patients
have had cancer and may suffer from chronic graft versus
host disease (cGvHD), which can occur six to 12 months
after a bone marrow transplant. “Patients with ocular
cGvHD have severe dry eye with constant, debilitating eye
pain and light sensitivity,” she explains.
PROSE patient Sheri Rapaport had no experience with
cancer but had developed keratoconus, a degenerative
corneal disease, in her 20s. She learned about PROSE
from a friend’s son who had leukemia and developed
cGvHD. He was a medical student, and had done some
research on the PROSE devices.
“I could see with the PROSE devices immediately,” says Rapaport.
All PROSE devices are customized with computer-aided design
(CAD) software to precisely fit the
patient’s unique eye shape and
are manufactured in the Boston
Foundation’s state-of-the-art lab.
It can take several months of customization to get the best fit. Dr. Shorter and her team
help to train patients on the devices which are removed at
bedtime and re-inserted in the morning.
PROSE devices can solve a variety of eye problems. Patients like Sheri Rapaport cannot see with spectacles and
her PROSE devices aid her vision. Other patients might
need them to permanently protect or temporarily heal the
ocular surface due to injury.
Rapaport says Dr. Shorter has been a calming influence
throughout her treatment. “It has been a real hopeful, positive process from the beginning.” She adds, “Now I can go
to the grocery store and see what is on the shelves…it’s
like PROSE has given me my independence back.”
Even better, Rapaport said she can now clearly see her
newborn grandchild. “It’s just been phenomenal.”
Rapaport, 67, had undergone four cornea transplants
over the previous four decades with only minimal success.
“Every procedure worked for a short time,” she explained,
“then the keratoconus took over again.” Eventually, Rapaport couldn’t drive anymore or perform everyday tasks due
to her severely diminished eyesight. “Even going to the
grocery store was a challenge,” she recalls.
OneVision | 7
STEM CELLS AND SIGHT
Can stem cell technology at the squeeze of an eyedropper promote healing and regeneration
for the worst injuries and diseases of the eye surface?
Severe and chronic ocular injuries and diseases have long
vexed ophthalmologists trying to find ways to accelerate
healing and promote regeneration of the eye surface.
Stem cell research might finally provide an answer.
this research to the clinic. We see the most difficult patients
that no one else is able to take care of.”
He adds that “the Department of Ophthalmology has a
long history of cultivating important research with the infrastructure to do top quality work.”
“We’ve never had very effective treatments for severe
eye injuries and for chronic conditions where the corneal
This particular project has been supported by the
surface cannot regenerate itself,” says Ali Djalilian, MD,
U.S. Department of Defense, which is seeking greater
Associate Professor of Ophthalmology/Cornea Service.
treatment options for eye injuries and combat-related
That’s why Djalilian, Director of the Infirmary’s Corneal
conditions. Djalilian’s project is also being supported with a
Epithelial Biology and Tissue Engigrant from the Vision for Tomorrow
neering Laboratory, is researching
Foundation, a Chicago-based
ways to apply stem cell-produced
organization that supports families
factors – specialized proteins that
affected by aniridia—an absence
“If this works, (Djalilian)
can get diseased or injured cells to
of the iris in one or both eyes, or
will literally be changing
heal – as a topical treatment on the
albinism—a disorder that prevents
eye surface.
the body’s ability to produce or
the course of treatment for
distribute melanin.
Djalilian anticipates that such stem
thousands of people.
cell-produced factors may be disHelen Mopsick, board member at
pensed through eyedrops or by
Vision for Tomorrow, said the orspecialized contact lenses that lock
ganization connected with Djalilian
the healing solution in place.
in 2011 and supports the research
because current treatment for aniridia is a cornea trans“We think this will be helpful for a wide range of patients
plant. Said Mopsick, “If this works, (Djalilian) will literally be
with severe injuries or diseases of the surface of the eye,”
changing the course of treatment for thousands of people.
says Djalilian of the 1 million dollar project, which launched
Part of the condition of aniridia is that if the cornea starts to
about a year ago and is roughly two to three years away
deteriorate in someone’s late teens or early twenties, the
from human trials.
injury just doesn’t heal.”
Stem cells are cultured in the Infirmary laboratory so such
factors can be collected,” says Djalilian. To date, most of his
studies have “been based on optimizing those conditions
and testing them in animal models.” This summer, the Department’s team is hoping to begin pre-clinical studies that
will eventually allow the U.S. Food and Drug Administration
to give the Department clearance to start clinical trials.
Stem cell research is a very hot topic right now in ophthalmology, but Djalilian says the Department provides a
unique home for this new technology to flourish. “As a department and a team, we are set up very well to translate
8
Mopsick added that Djalilian approached the foundation
and a lab visit made it a partnership. “He has quite a few
patients and we love finding researchers who are also in
clinic,” she said. “This is our first project with [the Department of Ophthalmology at the Illinois Eye and Ear Infirmary], and it’s been a very good experience: very responsive.
And we’ll be back.”
“As a department and a team, we are set up very well to translate this research to the clinic.
We see the most difficult patients that no one else is able to take care of.”
OneVision | 9
CORNEA AND REFRACTIVE
SURGERY
The Cornea and External Disease Service manages patients with diseases of the front of the eye including corneal
and conjunctival infections, keratoconus, cataracts, tumors
of the iris and conjunctiva, blepharitis, dry eye, corneal scarring, complications of trauma and ocular surgery as well as
hereditary corneal diseases like Fuchs’ Dystrophy. The service has extensive expertise in all forms of partial thickness
corneal transplantation including DMEK, DSAEK/ DSEK,
and DALK as well as traditional penetrating keratoplasty that
provides patients with the widest array of treatment options.
Those not eligible for human corneal transplantation may
qualify for our Artificial Cornea Program, which is the largest
program of its kind in the Midwest for implanting keratoprostheses. The service also provides access to state-of-the-art
imaging technology to quickly and accurately diagnose a
wide spectrum of diseases. Cornea specialists also work
with the Contact Lens Service to offer advanced contact
lens therapies including the PROSE lens and offer the opportunity to participate in the latest clinical trials for dry eye
diseases, corneal transplantation and corneal infections.
IMAGE: Photo of iris and pupil courtesy of the Eye Photography Service.
10
DIRECTOR
Elmer Y. Tu, MD
Professor of Clinical Ophthalmology
Director, Cornea Service
MEDICAL SCHOOL
University of Miami
RESIDENCY IN OPHTHALMOLOGY
University of Wisconsin
CLINICAL FELLOWSHIP
Bascom Palmer Eye Institute (Cornea)
Clinical Interests
Corneal transplantation including DMEK, DSAEK, DALK and Full
thickness corneal transplantation; Corneal infections and corneal
inflammatory disorders; Complex and routine cataract surgery
Research Interests
Corneal infections and inflammation; Corneal transplantation;
New surgical and drug therapies
Dimitri T. Azar, MD, MBA
Dean, University of Illinois College of Medicine
Distinguished Professor of Ophthalmology,
Bioengineering and Pharmacology
B.A. Field Chair in Ophthalmologic Research
MEDICAL SCHOOL
American University of Beirut, Lebanon
RESIDENCY IN OPHTHALMOLOGY
Massachusetts Eye and Ear Infirmary
CLINICAL FELLOWSHIP
Massachusetts Eye and Ear Infirmary (Cornea)
RESEARCH FELLOWSHIP
Schepens Eye Research Institute
GRADUATE SCHOOL
University of Chicago (MBA)
Clinical Interests
laser vision correction; cornea and cataract
surgery
M. Soledad Cortina, MD
Assistant Professor of Ophthalmology
Director, Comprehensive Ophthalmology Faculty
Practice (COFP) and General Eye Clinic
Director, Artificial Cornea Program
MEDICAL SCHOOL
University of Buenos Aires School of Medicine,
Argentina
Jose de la Cruz, MD
Assistant Professor of Ophthalmology
Co-Director, Millennium Park Eye Center
MEDICAL SCHOOL
Ponce School of Medicine, Puerto Rico
RESIDENCY IN OPHTHALMOLOGY
New York Eye and Ear Infirmary
RESIDENCY IN OPHTHALMOLOGY
Louisiana State University
CLINICAL FELLOWSHIP
Massachusetts Eye and Ear Infirmary (Cornea)
CLINICAL FELLOWSHIP
Illinois Eye and Ear Infirmary (Cornea)
GRADUATE SCHOOL
Indiana University at Bloomington (MS)
RESEARCH FELLOWSHIP
Louisiana State University, Neuroscience Center
Clinical Interests
Advances in keratoprosthesis transplantation;
Anterior segment imaging in cornea and refractive
surgery; Femtosecond technology for corneal
tranplantation
Clinical Interests
Ocular surface disease and high-risk corneal
transplantation including Boston keratoprosthesis;
Cataract surgery and endothelial keratoplasty
Research Interests
Sterile keratolysis in Boston keratprosthesis
patients; Optical properties of artificial corneas;
Corneal nerves and their regeneration after injury
Research Interests
Development of surgical devices for conjunctival
manipulation; New techniques in refractive surgery
and femtosecond assisted keratoplasty; Advanced
technology intraocular lenses for correction of
presbyopia and astigmatism
Ali R. Djalilian, MD
Sandeep Jain, MD
Mark I. Rosenblatt, MD, PhD, MBA
MEDICAL SCHOOL
University of Minnesota
MEDICAL SCHOOL
University of Delhi, India
RESIDENCY IN OPHTHALMOLOGY
University of Minnesota
RESIDENCY IN OPHTHALMOLOGY
Harkness Eye Institute
CLINICAL FELLOWSHIP
Cincinnati Eye Institute (Cornea)
CLINICAL FELLOWSHIP
Massachusetts Eye and Ear Infirmary (Cornea)
RESEARCH FELLOWSHIP
University of Minnesota (Cornea)
RESEARCH FELLOWSHIP
Wilmer Eye Institute (Cornea)
RESEARCH FELLOWSHIP
National Eye Institute (Ocular Immunology)
Clinical Interests
Dry Eye and Ocular surface disease; Ocular graftversus-host-disease; Neurotrophic keratitis
Research Interests
Matrix metalloproteinases in corneal wound healing
and angiogenesis; Refractive surgery; Optics;
Accommodating intraocular lenses
Associate Professor of Ophthalmology
Director, Corneal Epithelial Biology and Tissue
Engineering Laboratory
Clinical Interests
Ocular surface disease; Limbal stem cell deficiency;
Corneal and limbal stem cell transplantation;
Immunologic diseases of the cornea
Research Interests
Stem cell based therapy; Corneal wound healing;
Tissue engineering
Associate Professor of Ophthalmology
Director, Corneal Neurobiology Laboratory
Director, Dry Eye Service
Research Interests
Professor and Head
Department of Ophthalmology & Visual Sciences
Illinois Lions/Charles I. Young Chair in Ocular Research
Director, Corneal Regenerative Medicine Laboratory
MEDICAL SCHOOL
University of Miami (PhD, Biochemistry)
RESIDENCY IN OPHTHALMOLOGY
Massachusetts Eye and Ear Infirmary
CLINICAL FELLOWSHIP
Massachusetts Eye and Ear Infirmary (Cornea)
Molecular and cellular aspects of corneal nerve
regeneration; Molecular and cellular aspects of ocular
surface disease; Translational research
RESEARCH FELLOWSHIP
Schepens Eye Research Institute
GRADUATE SCHOOL
New York University (MBA)
Clinical Interests
Corneal disease; Cataract; Refractive surgery;
Ocular pain; Dry Eye disease; Keratoplasty
Research Interests
Ocular regenerative medicine; Corneal stem cells;
Corneal nerve regeneration; Angiogenesis; Tissue
engineering; Biomaterials; Nanomedicine
CORNEA SERVICE continued on next page
OneVision | 11
CORNEA AND REFRACTIVE SURGERY (CONT.)
Joel Sugar, MD
Joel Sugar MD Professor in Ophthalmology
Vice Chair, Clinical Operations
MEDICAL SCHOOL
University of Michigan
RESIDENCY IN OPHTHALMOLOGY
Washington University, St. Louis
CLINICAL FELLOWSHIP
University of Florida, Gainesville (Cornea)
Clinical Interests
Corneal disorders; Herpes simplex; Herpes zoster;
Congenital anomalies of the anterior eye
Research Interests
Keratoplasty outcomes; Herpes; Fuchs dystrophy
12
Charles Qian Yu, MD
Assistant Professor of Ophthalmology
MEDICAL SCHOOL
University of California Davis
RESIDENCY IN OPHTHALMOLOGY
Stanford University
CLINICAL FELLOWSHIP (CORNEA)
Cornell University
Clinical Interests
Cataract; Penetrating keratoplasty; Endothelial
keratoplasty; Keratoprosthesis
Research Interests
Corneal healing; Artificial cornea; LASIK clinical
trials; Virtual reality
CONTACT LENS
The Contact Lens Service provides care to patients requiring medically necessary contact lenses and related services.
Our doctors are nationally known for their clinical and research expertise and their ability to help patients with various
complex corneal diseases including: Keratoconus, Post-corneal transplant, Dry eye syndrome, Graft-versus-host disease
(GVHD), Limbal stem cell deficiency, Sjögren’s syndrome, Neurotrophic keratitis, Corneal scarring, Stevens-Johnson
syndrome, Post-LASIK, and Aphakia. We have extensive experience with all types of medically necessary contact lenses
including scleral, hybrid and rigid contact lenses as well as customized soft contact lenses. The service’s PROSE clinic
is one of only 12 clinic sites in America to offer BostonSight® PROSE treatment for patients with severely compromised
ocular function as a result of complex corneal disease.
###
DIRECTOR
Charlotte E. Joslin, OD, PhD, FAAO
Associate Professor of Ophthalmology
Department Affiliate, Epidemiology and
Biostatistics
Director, Contact Lens Service
OPTOMETRY SCHOOL
Ohio State University College of Optometry
RESIDENCY IN OPTOMETRY
Jesse Brown VA Medical Center and
Blind Rehabilitation Center of Hines VA Hospital
GRADUATE SCHOOL
University of Illinois at Chicago (PhD,
Epidemiology)
Clinical Interests
Medically necessary contact lenses for
diseases such as: Keratoconus; Post-corneal
transplant; Dry eye; Graft-versus-host disease
(GVHD); Limbal stem cell deficiency, Sjögren’s
syndrome, Neurotrophic keratitis; Corneal
scarring; Stevens-Johnson syndrome; PostLASIK
Timothy T. McMahon, OD, FAAO
Professor of Ophthalmology
Vice Chair for Optometry
OPTOMETRY SCHOOL
Illinois College of Optometry
RESIDENCY IN OPTOMETRY
Kansas City VA Medical Center
Clinical Interests
Medically necessary contact lenses; Corneal
topography; Anterior segment diseases
and injuries
Research Interests
Keratoconus and other corneal ectactic
conditions and diseases; Dry eye;
Blepharitis
Ellen Shorter, OD, FAAO
Assistant Professor of Ophthalmology
Director, Prosthetic Replacement of the
Ocular Surface Ecosystem (PROSE) Clinic
OPTOMETRY SCHOOL
Illinois College of Optometry
RESIDENCY IN OPTOMETRY
Jesse Brown VA Medial Center and Hines
VA Hospital
CLINICAL FELLOWSHIP
Boston Foundation for Sight (PROSE)
Clinical Interests
Ocular surface disease; Corneal ectasia;
Keratoconus; Keratoprosthesis
Research Interests
Dry eye; Adenoviral conjunctivitis
Research Interests
Epidemiology of various eye diseases and
infections; Racial differences in various eye and
other health-related outcomes
OneVision | 13
GLAUCOMA
Glaucoma is the leading cause of irreversible blindness in the world. Our Glaucoma Service is nationally
recognized as a center for the diagnosis and treatment of glaucoma in adults and children. It is a site
for testing investigational new drugs and has been
a leader in the use of laser and surgery to treat all
forms of the disease. Our service offers comprehensive care and management of all forms of glaucoma,
including specialized diagnostic testing and the latest
technologies for laser and surgical treatment. Faculty
members are actively involved in glaucoma research
and are nationally recognized as experts in their field.
DIRECTOR
Thasarat S. Vajaranant, MD
Associate Professor of Ophthalmology
Director, Glaucoma Service
MEDICAL SCHOOL
Chulalongkorn University, Thailand
RESIDENCY IN OPHTHALMOLOGY
Illinois Eye and Ear Infirmary
CLINICAL FELLOWSHIP
Illinois Eye and Ear Infirmary (Glaucoma)
RESEARCH FELLOWSHIP
Illinois Eye and Ear Infirmary (Low Vision)
Clinical Interests
Diagnosis and management of glaucoma and
cataract; Management of complex glaucoma and cataract;
International ophthalmology
Research Interests
Glaucoma epidemiology; Women’s eye health; Aging of the optic
nerve; Outcomes of glaucoma surgery; Management of glaucoma
after corneal transplants
IMAGE: Fundus photo highlighting optic nerve of glaucoma patient courtesy
of the Glaucoma Service.
14
OTHER CLINICAL FACULTY
David S. Hillman, MD
Ahmad A. Aref, MD
Assistant Professor of Ophthalmology
MEDICAL SCHOOL
Northwestern University
RESIDENCY IN OPHTHALMOLOGY
Penn State Hershey Eye Center
CLINICAL FELLOWSHIP
Bascom Palmer Eye Institute (Glaucoma)
Clinical Interests
Jacob T. Wilensky, MD
Jacob T. Wilensky MD Professor of Ophthalmology
Director, Glaucoma Fellowship Program
MEDICAL SCHOOL
Tulane University
RESIDENCY IN OPHTHALMOLOGY
Tulane University Affiliated Hospitals
CLINICAL FELLOWSHIP
Washington University, St. Louis (Glaucoma)
Complex cataract surgery; Trabeculectomy and
glaucoma drainage implant surgery for advanced
glaucomatous disease; Microinvasive glaucoma
surgery for mild/moderate glaucomatous disease;
Selective laser trabeculoplasty for open-angle
glaucomas; Laser iridotomy for angle-closure
glaucomas
RESEARCH FELLOWSHIP
Research Interests
Investigation of new drugs for glaucoma; Laser
therapy treatment for glaucoma
Surgical techniques in complex glaucomas; Risk
factor analysis of steroid-response glaucoma;
Glaucoma associated with retinal disorders; Novel
glaucoma medical therapies; Optic nerve imaging
Assistant Professor of
Clinical Ophthalmology
National Eye Institute (Glaucoma)
Clinical Interests
Diagnosis and treatment of glaucoma with special
emphasis on laser therapy
Mark W. Lunde, MD
Assistant Professor of
Clinical Ophthalmology
Research Interests
OneVision | 15
NEURO-OPHTHALMOLOGY
The Neuro-Ophthalmology Service offers expert
evaluations and treatment for neuro-ophthalmologic conditions, including: optic neuritis, idiopathic
intracranial hypertension (pseudotumor cerebri),
ischemic optic neuropathies, optic neuropathies of
unknown etiology, ocular myasthenia gravis, cranial
nerve palsies, thyroid eye disease and visual or oculomotor complications of stroke, brain tumors, multiple sclerosis and other neurological diseases. The
service facilitates and interprets a wide range of diagnostic testing relevant to the diagnosis and management of neuro-ophthalmic diseases, including: Goldmann and Humphrey perimetry, infrared pupilometry,
optical coherence tomography, electroretinography,
lumbar punctures and magnetic resonance imaging.
The service works closely with doctors in the University of Illinois Hospital and Health Sciences Systems’
departments of Neurosurgery, Neurology, Radiation
Oncology and Rheumatology to provide interdisciplinary, state-of-the-art treatments.
DIRECTOR
Heather E. Moss, MD, PhD
Assistant Professor of Ophthalmology
Director, Neuro-Ophthalmology Service
Director, Neuro-Ophthalmology Fellowship Program
MEDICAL SCHOOL
Harvard Medical School
RESIDENCY IN NEUROLOGY
University of Pennsylvania
CLINICAL FELLOWSHIP
University of Pennsylvania (Neuro-Ophthalmology)
GRADUATE SCHOOL
Harvard-MIT Division of Health Sciences and Technology (PhD,
Medical Engineering)
Clinical Interests
Idiopathic intracranial hypertension; Optic neuritis; Optic
neuropathies; Optic chiasm disorders; Visual disorders
with neurological causes; Ocular myasthenia gravis; Cranial
nerve palsies
Research Interests
Idiopathic intracranial hypertension; Optic neuritis; Visual system
dysfunction in amyotrophic lateral sclerosis
IMAGE: Brain MRI depicting orbital structures courtesy of iStock.
16
OTHER CLINICAL FACULTY
Anil Gulati, MD
James Goodwin, MD
Peter W. MacIntosh, MD
MEDICAL SCHOOL
MEDICAL SCHOOL
RESIDENCY IN NEUROLOGY
RESIDENCY IN OPHTHALMOLOGY
CLINICAL FELLOWSHIP
CLINICAL FELLOWSHIP
Clinical Interests
CLINICAL FELLOWSHIP
Associate Professor of Ophthalmology
University of Illinois College of Medicine
University of Minnesota
Bascom Palmer Eye Institute (NeuroOphthalmology)
Optic neuritis; Optic neuropathies;
Ophthalmoplegia; Visual field loss; Idiopathic
intracranial hypertension; Cranial nerve palsies
Research Interests
Optic neuritis; Autoimmune optic neuropathy; Optic
nerve decompression
Assistant Professor of
Clinical Ophthalmology
Assistant Professor of Ophthalmology
The Chicago Medical School
Stroger Cook County Hospital
Illinois Eye and Ear Infirmary (NeuroOphthalmology)
Massachusetts Eye and Ear Infirmary
(Oculoplastics)
Clinical Interests
Idiopathic intracranial hypertension; Diplopia;
Ptosis; Eyelid and orbital tumors; Orbital trauma
Research Interests
Thyroid eye disease; Nonarteritic anterior ischemic
optic neuropathy (NAION)
OneVision | 17
OCULOPLASTIC &
RECONSTRUCTIVE
SURGERY
The Oculoplastic & Reconstructive Surgery Service
provides assessment and treatment for conditions of
the eyelids, orbit, face and lacrimal system. Systemic
disease, trauma, birth defects and the aging process
can alter the area around the eyes. Conditions such
as blepharoptosis, ectropion, entropion, eyelid retraction, blepharospasm, epiphora, tumors of the ocular
adnexa and orbit and fractures of the orbit are just a
few of the conditions treated in this specialty. Patients
can be seen at both the Illinois Eye and Ear Infirmary
and the Millennium Park Eye Center.
DIRECTOR
Pete Setabutr, MD
Associate Professor of Ophthalmology
Director, Oculoplastic & Reconstructive Surgery Service
Co-Director, Millennium Park Eye Center
MEDICAL SCHOOL
University of Texas-Houston
RESIDENCY IN OPHTHALMOLOGY
University of Texas-Houston
CLINICAL FELLOWSHIP
Illinois Eye and Ear Infirmary (Oculoplastics)
Clinical Interests
Cosmetic and reconstructive eyelid surgery; Orbital surgery;
Diseases of the lacrimal system
Research Interests
Diseases of the eyelid; Diseases of the orbit; Epidemiological
international vision research
IMAGE: Artistic rendering of a human skull courtesy of Lisa Birmingham.
18
Vinay K. Aakalu, MD, MPH
Amjad Z. Ahmad, MD
MEDICAL SCHOOL
MEDICAL SCHOOL
RESIDENCY IN OPHTHALMOLOGY
RESIDENCY IN OPHTHALMOLOGY
CLINICAL FELLOWSHIP
CLINICAL FELLOWSHIP
Assistant Professor of Ophthalmology
Director, Lacrimal Cell Biology Laboratory
Mount Sinai School of Medicine
Illinois Eye and Ear Infirmary
Illinois Eye and Ear Infirmary (Oculoplastics)
GRADUATE SCHOOL
Columbia University (MPH)
Clinical Interests
Thyroid eye disease; Orbital tumors; Facial and
ocular trauma; Ocular surface disease and scarring;
Inflammatory orbital disease; Congenital eyelid and
orbital disorders; Eye socket reconstruction; Facial
palsies; Eyelid malposition; Lacrimal disease;
Aesthetic surgery and treatments
Assistant Professor of
Clinical Ophthalmology
University of Michigan
Kellogg Eye Institute
Kellogg Eye Institute (Oculoplastic &
Reconstructive Surgery)
CLINICAL INTERESTS
Cosmetic eyelid surgery; Thyroid eye disease;
Eyelid reconstruction surgery; Ptosis
RESEARCH INTERESTS
Cosmetic eyelid surgery
Peter W. MacIntosh, MD
Assistant Professor of Ophthalmology
MEDICAL SCHOOL
The Chicago Medical School
RESIDENCY IN OPHTHALMOLOGY
Stroger Cook County Hospital
CLINICAL FELLOWSHIP
Illinois Eye and Ear Infirmary (NeuroOphthalmology)
CLINICAL FELLOWSHIP
Massachusetts Eye and Ear Infirmary
(Oculoplastics)
Clinical Interests
Lacrimal drainage surgery; Ptosis
Research Interests
Thyroid eye disease; Nonarteritic anterior ischemic
optic neuropathy (NAION)
Research Interests
Regenerative medicine; Lacrimal cell biology; Dry
eye disease; Cell based therapies; Orbital imaging;
Orbital oncology; Novel and minimally invasive
orbital and aesthetic surgery
Allen M. Putterman, MD, FACS
Professor of Ophthalmology
MEDICAL SCHOOL
University of Wisconsin
RESIDENCY IN OPHTHALMOLOGY
Michael Reese Hospital and Medical Center
CLINICAL FELLOWSHIP
Manhattan Eye, Ear and Throat Hospital
(Oculoplastics)
Clinical Interests
Aesthetic eyelid and facial plastic surgery; Upper
eyelid ptosis surgery; Thyroid eyelid and orbital
problems; Eyelid and orbital tumors; Tear duct
drainage surgery
Research Interests
Development of procedures and instruments for
oculofacial plastic surgery
OneVision | 19
PEDIATRIC
OPHTHALMOLOGY & ADULT
STRABISMUS
The Pediatric Ophthalmology & Adult Strabismus
Service offers general pediatric eye care, including
exams for newborns and children up to 18 years of
age. This service also provides other specialty clinics
treating rare and unusual children’s eye disorders, including glaucoma and genetic, neurocutaneous, and
neuro-ophthalmologic disorders. The doctors in this
service specialize in strabismus (eye alignment disorders) in adults as well as children. Additional care
providers include certified orthoptists and an oculoplastic and reconstructive surgeon.
DIRECTOR
Nathalie F. Azar, MD
Associate Professor of Clinical Ophthalmology
Director, Pediatric Ophthalmology & Adult Strabismus Service
MEDICAL SCHOOL
Boston University
RESIDENCY IN OPHTHALMOLOGY
George Washington University
CLINICAL FELLOWSHIP
Wilmer Eye Institute (Pediatric Ophthalmology)
Clinical Interests
Adult strabismus; Graves ophthalmopathy; Paralytic
and restrictive strabismus; Amblyopia; Pediatric
strabismus, cataracts and glaucoma
Research Interests
Amblyopia; Eye movement disorders; Surgical treatment
techniques for strabismus; Pediatric ocular anomalies
20
Benjamin Mathew, MD
Assistant Professor of Clinical Ophthalmology
MEDICAL SCHOOL
University of Manitoba
RESIDENCY IN OPHTHALMOLOGY
LSU Eye Center/ Alton Ochsner Clinic Foundation
University of Ottawa Eye Institute
RESEARCH FELLOWSHIP
University of Ottawa Eye Institute (Ophthalmic
Pathology)
IIrene H. Maumenee, MD
Marilyn T. Miller, MD, MS
Research Professor of Ophthalmology
Director, Ocular Genetics Laboratory
Professor of Ophthalmology
MEDICAL SCHOOL
MEDICAL SCHOOL
University of Illinois College of Medicine, Chicago
University of Göttingen, Germany
RESIDENCY IN OPHTHALMOLOGY
RESEARCH FELLOWSHIPS
University of Geneva (Ophthalmology and Genetics)
University of Hawaii (Population Genetics)
Johns Hopkins University (Medical Genetics)
PRECEPTORSHIP IN OPHTHALMOLOGY
Wilmer Eye Institute
CLINICAL FELLOWSHIP
University of Wisconsin (Pediatric Ophthalmology)
Clinical Interests
General pediatric ophthalmology; Pediatric cataract;
Blocked tear duct; Retinopathy of prematurity
Research Interests
Ophthalmic optics; Automated measurement of
strabismus
Illinois Eye and Ear Infirmary
CLINICAL FELLOWSHIP
Illinois Eye and Ear Infirmary and Cook County
Hospitals (Strabismus)
GRADUATE SCHOOL
University of Illinois at Chicago (MS, Microbiology)
Clinical Interests
Management of complications of the Marfan
syndrome and related connective tissue diseases;
Clinical diagnosis of patients with rare genetic
diseases of the visual system
Research Interests
Finding new genes and mutations in hereditary eye
diseases through application of whole exome and
whole genome sequencing strategies; Special
interest in Leber congenital amaurosis
Clinical Interests
International ophthalmology with special interest
in training issues in pediatric ophthalmology;
Craniofacial syndromes; Teratology; Duane
syndrome
Research Interests
Teratology: craniofacial anomalies; Duane
syndrome
OTHER CLINICAL FACULTY
Javaneh Abbasian,
MD
Assistant Professor of
Ophthalmology
Kimberlee Curnyn,
MD
Lawrence Kaufman,
MD, PhD
R.V. Paul Chan, MD,
MSc, FACS
Felix Y. Chau, MD
Assistant Professor of
Clinical Ophthalmology
Associate Professor of
Clinical Ophthalmology
Ben Ticho, MD
Associate Professor of
Clinical Ophthalmology
SPECIALTY FACULTY
Vinay K. Aakalu, MD,
MPH
Oculoplastic and
Reconstructive Surgery
Pediatric Retina
Pediatric Retina
OneVision | 21
RETINA
The Retina Service specializes in treating patients
with both medical and surgical retinal vascular and
vitreoretinal disorders, such as: age-related macular
degeneration, vein occlusion, sickle cell eye disease,
ocular complications of diabetes, retinal detachment,
vitreomacular adhesion, retinopathy of prematurity,
retinitis pigmentosa, intraocular tumors and severe
eye trauma. The doctors in this service are skilled
specialists in laser and other medical treatment of
the retina, vitreoretinal surgery and complex retinal
detachment repair.
DIRECTOR
Jennifer I. Lim, MD, FARVO
Marion H. Schenk Esq Chair in Ophthalmology for
Research of the Aging Eye
Professor of Ophthalmology
Director, Retina Service
MEDICAL SCHOOL
Northwestern University
RESIDENCY IN OPHTHALMOLOGY
Illinois Eye and Ear Infirmary
CLINICAL FELLOWSHIP
Wilmer Eye Institute (Retina)
Clinical Interests
Diabetic retinopathy; Age-related macular degeneration; Retinal
vascular diseases; Macular diseases; Retinal detachments and
vitreoretinal disorders; Ocular tumors; Retinal degenerations
Research Interests
Medical and surgical treatments; Clinical trials to evaluate new
medical and surgical treatments of retinal diseases; Retinal
imaging as applied to management of retinal diseases and
determination of pathophysiology; Collaborative projects with
basic scientists on pathogenesis of retinal diseases
IMAGE: Immunofluorescence image of retinal cell layers courtesy of the
Vitreoretinal Microsurgery Laboratory.
22
Norman P. Blair, MD
Professor of Ophthalmology
Director, Laboratory of Retinal Circulation and
Metabolism
MEDICAL SCHOOL
Indiana University
RESIDENCY IN OPHTHALMOLOGY
Massachusetts Eye & Ear Infirmary
CLINICAL FELLOWSHIP
Retina Associates/Massachusetts Eye & Ear
Infirmary (Retina)
CLINICAL FELLOWSHIP
Illinois Eye and Ear Infirmary (Ophthalmic
Pathology)
RESEARCH FELLOWSHIP
Schepens Eye Research Institute
Research Interests
Retinal oxygenation; Retinal energy metabolism;
Retinal blood flow and ischemia; Diabetic
retinopathy
Yannek I. Leiderman, MD, PhD
Assistant Professor of Ophthalmology
Director, Vitreoretinal Microsurgery Laboratory
MEDICAL SCHOOL
George Washington University
National Institutes of Health Partnership (PhD,
Molecular Pathobiology)
RESIDENCY IN OPHTHALMOLOGY
Massachusetts Eye and Ear Infirmary
CLINICAL FELLOWSHIP
Massachusetts Eye and Ear Infirmary
(Vitreoetinal Surgery)
Clinical Interests
Vitreoretinal surgical diseases; Diabetic
eye disease; Complex retinal detachment;
Proliferative vitreoretinopathy (PVR); Macular
surgery; Treatment of aphakia and placement
of secondary intraocular lenses
Research Interests
Effectiveness of ophthalmic surgical
interventions in diseases of the retina and
vitreous; High-fidelity modeling of novel
surgical devices and experimental techniques
in microsurgery
Felix Y. Chau, MD
Assistant Professor of Ophthalmology
Director, Retinal Bioengineering Laboratory
MEDICAL SCHOOL
University of Iowa
RESIDENCY IN OPHTHALMOLOGY
Duke University Eye Center
CLINICAL FELLOWSHIP
Illinois Eye and Ear Infirmary (Retina)
Clinical Interests
Pediatric and adult retinal diseases; Retinopathy
of prematurity (ROP); Retinoblastoma; Rare
congenital and inherited retinal diseases;
Proliferative vitreoretinopathy (PVR); Diabetic
retinopathy; Macular degeneration; Cystoid macular
edema
Research Interests
R. V. Paul Chan, MD, MSc, FACS
Professor of Ophthalmology
Vice Chair for Global Ophthalmology
Co-Director Vitreoretinal Fellowship Training
Program
MEDICAL SCHOOL
Temple University
RESIDENCY IN OPHTHALMOLOGY
New York-Presbyterian Hospital, Cornell University
CLINICAL FELLOWSHIP
Massachusetts Eye and Ear Infirmary (Retina)
Clinical Interests
Adult and pediatric retinal disease including
retinopathy of prematurity (ROP); Retinal
vascular diseases; Eye trauma; Eye infections/
endophthalmitis; Diabetic retinopathy; Age-related
macular degeneration
Medical and surgical treatments; Experimental
models and risk factors for retinal diseases;
Engineering applications in ophthalmology
Research Interests
William F. Mieler, MD, FARVO
Lawrence J. Ulanski, MD, II
Cless Family Professor in Ophthalmology
Vice Chair for Education
Director, Ocular Oncology Clinic
Director, Residency and Vitreoretinal Fellowship
Training
MEDICAL SCHOOL
University of Wisconsin-Madison
RESIDENCY IN OPHTHALMOLOGY
Bascom Palmer Eye Institute
CLINICAL FELLOWSHIP
Global ophthalmology; Telemedicine and teleeducation; New methods of diagnosing and
managing pediatric retinal disease
Assistant Professor of Clinical Ophthalmology
MEDICAL SCHOOL
University of Michigan
RESIDENCY IN OPHTHALMOLOGY
William Beaumont Eye Institute
CLINICAL FELLOWSHIPS
University of Toronto, (Vitreo-Retina
and Ocular Oncology)
Illinois Eye and Ear Infirmary (Uveitis)
The Eye Institute, Medical College of Wisconsin
(Retina-Vitreous)
CLINICAL FELLOWSHIP
Wills Eye Hospital (Ocular Oncology)
Clinical Interests
Diseases of the macula, retina and vitreous; Agerelated macular degeneration; Diabetic macular
edema; Venous occlusive diseases; Vitreoretinal
interface disorders; Ocular oncology
Research Interests
Ocular pharmacology; Intraocular tumors; Ocular
imaging
OneVision | 23
UVEITIS
Uveitis causes up to 20 percent of blindness in the United States. The Uveitis Service treats patients with inflammation of
the uveal tract, the middle vascular layers of the eye critical to its normal function. Because of the rich circulation of blood
throughout this area and its proximity to other important parts of the eye, the uvea is susceptible to immune disorders.
Patients are referred to this service for the diagnosis and management of infectious and non-infectious ocular inflammatory conditions such as scleritis and anterior, intermediate and posterior uveitis. Treatment with steroid-sparing systemic
immunomodulatory therapy is offered when appropriate. The service also performs procedures for its uveitis patients such
as the insertion of steroid eluting implants as well as surgical management of complex uveitic cataracts.
CO-DIRECTOR
CO-DIRECTOR
Pooja Bhat, MD
Ann-Marie Lobo, MD
Assistant Professor of Ophthalmology
Director, Uveitis Service
MEDICAL SCHOOL
Lokmanya Tilak Municipal Medical College and Hospital, India
RESIDENCY IN OPHTHALMOLOGY
Northwestern University
CLINICAL FELLOWSHIPS
Northwestern University (Uveitis)
Massachusetts Eye and Ear Infirmary (Ophthalmic Pathology)
RESEARCH FELLOWSHIP
Massachusetts Eye Research and Surgery Institution (Uveitis)
Clinical Interests
Scleritis; Anterior, intermediate and posterior uveitis; VogtKoyanagi-Harada (VKH) disease; Behcet’s syndrome; Sarcoidosis;
Infectious retinopathies; White dot syndromes
Research Interests
Systemic immunosuppression for ocular inflammatory
conditions; Seasonal variations in autoimmune diseases; Disc
and scleral changes in VKH; Schisis in pars planitis; Anterior
segment and posterior segment imaging with optical coherence
tomography
24
Assistant Professor of Ophthalmology
MEDICAL SCHOOL
Louisiana State University New Orleans
RESIDENCY IN OPHTHALMOLOGY
Massachusetts Eye and Ear Infirmary
CLINICAL FELLOWSHIP (OCULAR
IMMUNOLOGY/UVEITIS)
Massachusetts Eye and Ear Infirmary
Clinical Interests
Ocular inflammatory disease, including infectious
and non-infectious uveitis, scleritis and ocular
surface inflammation; Cataract surgery
Research Interests
Diagnostic testing in infectious and non-infectious
uveitis; Outcomes of biologic response modifier
therapies in the treatment of uveitis; Morbidity
of childhood uveitis; Systemic infections and eye
disease
IMAGE: Colorized OCT image of VKH patient’s retina courtesy of the Uveitis
Service.
LOW VISION
PATHOLOGY
This specialized service introduces patients with low
vision to technology and techniques to enhance their
remaining sight and facilitate their independence. A
low-vision optometrist and a certified low-vision therapist work as a team to provide clinical examination
and visual skills assessment. Therapies include special optical and electronic devices, ergonomic equipment and new visual skills training to address routine
daily tasks such as reading, writing, managing medication, cooking, locating and sign reading.
The Ophthalmic Pathology Laboratory is a joint program of the Departments of Pathology and Ophthalmology that provides diagnostic services to patients
and physicians within and outside Illinois. The laboratory is integrated with the other clinical laboratories in
the University of Illinois Hospital and Health Sciences
System, making it possible to utilize the latest cutting-edge diagnostic techniques in immunopathology
and molecular pathology available in the diagnosis of
ocular disorders.
DIRECTOR
DIRECTOR
Joan A. Stelmack, OD, MPH
Amy Y. Lin, MD
OPTOMETRY SCHOOL
MEDICAL SCHOOL
GRADUATE SCHOOL
RESIDENCY
Associate Professor of Clinical Ophthalmology
Director, Low Vision Service
Illinois College of Optometry
Johns Hopkins University (MPH)
Clinical Interests
Rehabilitation of patients with vision loss
Research Interests
Creating multicenter clinical trials and observational studies
to evaluate rehabilitation strategies and devices to restore or
enhance vision
Assistant Professor of Ophthalmology and Pathology
Director, Ophthalmic Pathology Laboratory
Johns Hopkins University
Illinois Eye and Ear Infirmary (in Ophthalmology)
University of Illinois College of Medicine (in Pathology)
CLINICAL FELLOWSHIP (OPHTHALMIC PATHOLOGY)
Illinois Eye and Ear Infirmary
Clinical Interests
Eye pathology; Pathologic basis of ophthalmic disease
Research Interests
Ocular oncology; Pathology education; Virtual microscopy for
learning pathology; Team-based learning
OneVision | 25
COMPREHENSIVE
OPHTHALMOLOGY FACULTY
PRACTICE (COFP)
The Comprehensive Eye Clinic is a premiere ophthalmology
practice run by recognized Board Certified ophthalmologists.
The clinic provides: comprehensive eye exams, eyeglass prescriptions and contact lens fitting. The more extensive services include: state-of-the-art cataract surgery, femtosecond
laser assisted cataract surgery, premium intraocular lenses
and the management of common and complex eye diseases.
Same-day or next-day appointments are available.
GENERAL EYE CLINIC (GEC)
The General Eye Clinic is the heart of our department
and serves as the first point of contact for many of the
Infirmary’s neediest patients, as well as a primary location for ophthalmic graduate medical education. Our dedicated residents and world-class faculty provide a wide
spectrum of collaborative ophthalmic care ranging from
managing common eye diseases and delivering routine
eye exams to performing complex medical and surgical
cases including cataract, glaucoma and retinal procedures. Special emphasis is placed on providing strong
continuity of patient care. The GEC sees emergent referrals from outside providers from throughout the region
and accepts “walk-in” patients with acute eye disease.
DIRECTOR
M. Soledad Cortina, MD
(Cornea)
Assistant Professor of Ophthalmology
Director, COFP and GEC
Director, Artificial Cornea Program
COFP FACULTY
Jose de la Cruz, MD Sandeep Jain, MD
(Cornea)
(Cornea)
Timothy McMahon, Ellen Shorter, OD,
OD, FAAO
FAAO (Contact Lens)
(Contact Lens)
Ahmad Aref, MD
(Glaucoma)
Pooja Bhat, MD
(Uveitis)
Ali Djalilian, MD
(Cornea)
Bryan Kim, MD
(Cornea)
Ann-Marie Lobo, MD
(Uveitis)
Peter Macintosh,
MD
(Neuro-Oph and
Oculoplastics)
Mark Rosenblatt,
MD, PhD, MBA
(Cornea)
Joel Sugar, MD
(Cornea)
Elmer Tu, MD
(Cornea)
Charles Yu, MD
(Cornea)
GEC FACULTY
Anthony G. Finder, MD
Assistant Professor of Clinical
Ophthalmology
MEDICAL SCHOOL
Northwestern University
RESIDENCY IN OPHTHALMOLOGY
Michael Reese Hospital and Medical Center
Clinical Interests
General Ophthalmology; Early diagnosis and
medical management of glaucoma; Analysis
of problems related to ophthalmic optics
and refraction; Resident education
26
MILLENNIUM
PARK EYE
CENTER
(MPEC)
The Millennium Park Eye Center (MPEC) is the conveniently
located city-center clinic of the
Illinois Eye and Ear Infirmary.
Ophthalmologists and Optometrists seeing patients at the
MPEC are all members of the
Department of Ophthalmology & Visual Sciences faculty.
They diagnose and treat a
wide range of eye conditions
every day, from common eye
problems to the most complex
ophthalmic issues. The center
utilizes the most advanced eye
care technology in vision care
available, with state-of-the-art
diagnostic and surgical instruments.
IMAGE: Cloud Gate sculpture in Chicago’s
Millennium Park. Photographer: James
Pharaon at iStock.
CO-DIRECTOR
CO-DIRECTOR
Jose de la Cruz, MD
(Cornea)
Pete Setabutr, MD
(Oculoplastic & Reconstructive Surgery)
Ahmad Aref, MD
(Glaucoma)
Dimitri Azar, MD,
MBA (Cornea)
R. V. Paul Chan, MD,
Nathalie Azar, MD
(Pediatric Ophthalmology MSc, FACS (Retina)
& Adult Strabismus)
Timothy McMahon,
OD, FAAO
(Contact Lens)
William Mieler, MD
(Retina)
Heather Moss, MD,
PhD (NeuroOphthalmology)
Mark Rosenblatt,
MD, PhD, MBA
(Cornea)
OneVision | 27
RESEARCH FACULTY
The Department of Ophthalmology and Visual Sciences has a history of dedicated commitment and record of prominent
contributions to vision science research. The overarching goal for the research program is to address the significant challenges central to understanding, treating and preventing blinding eye disease. The program encompasses exemplary and
pioneering research in the most critical areas of vision research, including investigations to understand the mechanisms
of potentially blinding eye diseases, the development of innovative techniques and instruments for diagnosing and monitoring the progression of eye diseases, genome-wide association studies, visual psychophysics, retinal processing, and
visual neurophysiology. The department maintains a tradition of excellence in collaborative and interdisciplinary research
that has advanced knowledge in basic vision science and facilitated translation of findings to improve clinical care of patients with eye diseases.
Mahnaz Shahidi, PhD
Vice Chair and Research Director
Morton F. Goldberg Professor of Ophthalmology
Professor of Physics and Bioengineering
Director, Applied Physics Laboratory
GRADUATE SCHOOL
University of Illinois at Chicago (MS, PhD, Atomic
and Molecular Physics)
Research Interests
Development and application of optical imaging
systems for quantitative assessment of eye
diseases, including diabetic retinopathy, age-related
macular degeneration and sickle cell retinopathy
Dingcai Cao, PhD
Xiaoyi “Raymond” Gao, PhD
GRADUATE SCHOOL
GRADUATE SCHOOL
Associate Professor of Ophthalmology
Director, Visual Perception Laboratory
Beijing University (MS, Biopsychology)
University of Chicago (MS, Statistics)
University of Chicago (PhD, Biopsychology)
Research Interests
Melanopsin-based visual perception and circadian
rhythm; Rod-cone Interaction; Color perception;
Retinal physiology; Lighting and health; Acute
and chronic alcohol effect on vision and circadian
rhythm
IMAGE: OCT image with retinal layers delineated courtesy of the Applied
Physics Laboratory.
28
Associate Professor of Ophthalmology
Director, Quantitative Ocular Genomics Laboratory
North Carolina State University (PhD,
Bioinformatics-Statistics)
RESEARCH FELLOWSHIPS
Duke University Center for Human Genetics
Miami Institute for Human Genomics
Research Interests
Ocular genomics; Glaucoma; Diabetic retinopathy;
Age-related macular degeneration; Human genetics;
Statistical genomics; Bioinformatics
Joelle A. Hallak, PhD
Assistant Professor of Ophthalmology
Executive Director, Ophthalmology Center
for Clinical Trials and Translational Studies
GRADUATE SCHOOL
University of Illinois at Chicago
(MS, PhD, Epidemiology)
Research Interests
Ocular epidemiological research; Mental health;
biological and genetic markers; Comparative
effectiveness research and statistical analysis of
complex data
David R. Pepperberg, PhD, FARVO
Searls-Schenk Professor of Ophthalmology
Director, Photoreceptor Research Laboratory
GRADUATE SCHOOL
Massachusetts Institute of Technology (PhD,
Biophysics)
RESEARCH FELLOWSHIP
Harvard University (Vision Physiology)
Research Interests
Developing new molecular therapies that delay
the progression of, and restore vision lost in,
photoreceptor degenerative diseases such as agerelated macular degeneration (AMD)
Nalin M. Kumar, DPhil
Professor of Ophthalmology
GRADUATE SCHOOL
University of Oxford, UK (DPhil Biochemistry)
RESEARCH FELLOWSHIP
Baylor College of Medicine (Cell and Molecular
Biology)
Research Interests
Intercellular channels (gap junctions) and their
involvement in the processes and mechanisms that
are necessary for vision
Deepak Shukla, PhD
Marion H. Schenk Esq. Professor in Ophthalmology
for Research of the Aging Eye
Professor of Ophthalmology, Microbiology and
Immunology
Director, Ocular Virology Laboratory
J. Jason McAnany, PhD
Assistant Professor of Ophthalmology
Director, Clinical Psychophysics and
Electrophysiology Laboratory
GRADUATE SCHOOL
University of Illinois at Chicago (MA, PhD,
Behavioral Neuroscience)
RESEARCH FELLOWSHIP
University of Illinois College of Medicine
(Psychophysics and Electrophysiology)
Research Interests
Electroretinography; Psychophysics; Pupillometry;
Retinal imaging; Acquired and inherited retinal
disease
Xincheng Yao, PhD
Professor of Bioengineering and Ophthalmology
Director, Biomedical Optics and Functional Imaging
Laboratory
GRADUATE SCHOOL
University of Illinois at Chicago (PhD , Microbiology
and Immunology)
Harbin Institute of Technology, China (MEng,
Optical Instrumentation)
Institute of Physics Chinese Academy of Sciences
(PhD, Optics)
RESEARCH FELLOWSHIP
Research Interests
GRADUATE SCHOOL
Northwestern University (Virology and
Immunology)
Biomedical optics; Retinal imaging; Experimental
biophysics
Research Interests
Ocular herpes virus infection mechanisms;
Development of new therapeutic strategies against
viral diseases of the aging eye; Herpes virus
vaccine development
OneVision | 29
RESEARCH FACULTY (CONTINUED)
Jin-Hong Robert Chang, PhD
Research Assistant Professor of Ophthalmology
Director, Angiogenesis Research Laboratory
GRADUATE SCHOOL
University of Mississippi (PhD, Biochemistry)
RESEARCH FELLOWSHIP
University of Virginia (Microbiology)
Research Interests
The role of VEGFR1, R2 and R3 activity in vitro
and in vivo with the broader goal of characterizing
the intrinsic factors of lymphatic cells that regulate
corneal angiogenesis and lymphangiogenesis;
Development of targeted therapies for corneal
injury and disease
Research Assistant Professor of
Ophthalmology
Corneal Epithelial Biology and Tissue
Engineering Laboratory
MEDICAL SCHOOL
Tehran University of Medical Sciences, Iran
RESEARCH FELLOWSHIP
University of Illinois College of Medicine
(Biology and Tissue Engineering)
Research Interests
Translational studies in ocular surface disease;
Limbal stem cell deficiency; Refractive surgery;
Clinical trials and population-based studies;
Mesenchymal stem cell based therapy; Corneal
innate immunity
Victor H. Guaiquil, PhD
Kyu Yeon Han, PhD
GRADUATE SCHOOL
GRADUATE SCHOOL
Assistant Research Professor of Ophthalmology
Corneal Regenerative Medicine Laboratory
University Austral, Chile (MS)
SUNY Downstate Medical Center, New York (PhD,
Molecular and Cellular Biology)
RESEARCH FELLOWSHIPS
Memorial Sloan-Kettering Cancer Center
Hospital for Special Surgery, New York
Research Interests
Cellular and molecular mechanisms involved
in angiogenesis and neurogenesis in the retina
and cornea; Cornea nerve regeneration; Oxygen
induced retinopathy
30
Medi Eslani, MD
Research Assistant Professor of Ophthalmology
Metalloproteinases Research Laboratory
Michael A. Grassi, MD
Research Associate Professor of Ophthalmology
Director, Retinal Chemical Genomics Laboratory
MEDICAL SCHOOL
Northwestern University
RESIDENCY IN OPHTHALMOLOGY
University of Iowa
CLINICAL FELLOWSHIP
University of Iowa (Medical Retina)
RESEARCH FELLOWSHIP
University of Iowa (Molecular Ophthalmology)
Research Interests
Improving the treatment of retinal disease; Using
cell-based models of retinal disease in genomic and
chemical high throughput studies to identify key
pathways and novel therapeutic targets
Zeeshan Pasha, MD, PhD, MPH
Research Assistant Professor of Ophthalmology
Corneal Regenerative Medicine Laboratory
Lacrimal Cell Biology Laboratory
Suwon University, Korea (MS, Genetic Engineering)
Kyung Hee University, Korea (PhD, Oncology)
MEDICAL SCHOOL
RESEARCH FELLOWSHIP
GRADUATE SCHOOL
Research Interests
RESEARCH FELLOWSHIP
University of Illinois College of Medicine
(Ophthalmology)
Vascular angiogenesis in vitro and in vivo; The
function of membrane type I metalloproteinase in
cornea angiogenesis
Bahuddin Zakaryia University, Pakistan
University of Punjab, Pakistan (PhD, Stem Cell Therapy)
University of Illinois at Chicago (MPH)
University of Illinois at Chicago (Pharmacology)
Research Interests
Stem cell based therapeutics; Induced pluripotent, adult
and embryonic stem cells; Regenerative medicine; Small
molecules; Angiogenesis; Drug screening; Clinical Trials;
Translational research
RESEARCH FACULTY (CONTINUED)
Joy Sarkar, PhD
Research Assistant Professor of Ophthalmology
Corneal Neurobiology Laboratory
GRADUATE SCHOOL
University of Mumbai (MS, Microbiology)
HN Hospital and Research Center, India
(PhD, Biochemistry)
RESEARCH FELLOWSHIPS
Tata Institute of Fundamental Research, India
(Biology)
Northwestern University
(Cellular and Molecular Biology)
Research Interests
Molecular and cellular aspects of dry eye
disease; Innate immune mechanisms in dry eye;
Role of neutrophil extracellular traps (NETS)
and regulatory mechanisms in dry eye; Corneal
nerve regeneration after injury
Wallace Chamon,
MD
Charles Kinnaird,
OD
Paul Knepper,
MD, PhD
Anthony Peter Adamis, MD
Eric C. Beyer, MD, PhD
Michael Cho, PhD
Lisa Ebihara, MD, PhD
Gerald Fishman, MD
Robert Folberg, MD
Craig Foster, PhD
David Freedman, PhD
Ken-Ichiro Fukuchi, MD, PhD
Richard A. Gemeinhart, PhD
Debra Goldstein, MD
John R. Hetling, PhD
Yulia Komarova, PhD
Jie Liang, PhD
Kirk Packo, MD
Robert Paul Malchow, PhD
Asrar Malik, PhD
Sekhar Reddy, PhD
Daniel Roberts, OD, PhD
Steven Roth, MD
Alfred Rosenbloom, OD
William H. Seiple, PhD
Michael Shapiro, MD
Murray Sherman, PhD
Satoru Suzuki, PhD
Janet P. Szlyk, PhD
Howard Tessler, MD
Vaibhav Tiwari, PhD
Kimani Toussaint, PhD
Kazuo Tsubota, MD
Xiaojing Yang, PhD
CLINICAL VOLUNTEER FACULTY
ADJUNCT FACULTY
Norma Allemann,
MD
AFFILIATED & JOINT COURTESY
FACULTY
Molly Gilbert, MD
Daniel Alter, MD, PhD
David Badawi, MD
Adrienne Berman, MD
Harit Bhatt, MD
Michael Blair, MD
Rebekah Braslow, MD
Victoria Butcko, OD
Robert Egel, MD
Steven Eiden, OD
Timothy Flood, MD
Enrique Garcia-Valenzuela, MD
Jon Gieser, MD
Daniel Greenberg, MD
Jingtao Guo, MD
Rama Jager, MD, MBA
Katherine Hare, MD
Bruce Kaplan, MD
Manali D. Kalra, MD
Yuri Kim Kerns, MD
Bryan Kim, MD
Spero Kinnas, MD
Timothy Kisla, DO
Sheridan Lam, MD
Janet Lee, MD
David Lubeck, MD
Smajo Osmanovic, MD
Anna Park, MD
Rakhi Patil, MD
Michael Paxhia, MD
Richard Quinones, MD
Pervez Rasul, MD
Kenneth Resnick, MD
Alfred Rosenbloom, OD
Veeral Sheth, MD
Sriram Sonty, MD
Thomas Stelmack, OD
Daniel Tepper, MD
Charles Vygantas, MD
Robert Weiss, MD
Chloe Winterbotham, MD
IMAGE: Immunofluorescence image of conjunctival epithelium cells in ptosis
surgical specimens courtesy of the Lacrimal Cell Biology Laboratory.
OneVision | 31
SPONSORED RESEARCH
July 1, 2013 – June 30, 2015
FEDERALLY SPONSORED GRANTS
32
INVESTIGATOR
PROJECT TITLE
FUNDING SOURCE
Vinay Aakalu, MD, MPH
Study of Accessory Lacrimal Gland and Precursor Cell Biology
National Eye Institute
Dimitri Azar, MD, MBA
UIC K12 Independent Clinical Vision Scientist Development Program
National Eye Institute
Dimitri Azar, MD, MBA
Metalloproteinase Expression in Corneal Wound
National Eye Institute
Dingcai Cao, PhD
Alcohol Stimulations and Sedation in Binge Drinkers
National Institute of Alcohol Abuse and Alcoholism *
Dingcai Cao, PhD
Neural Stem Cell Based Virotherapy for Malignant Glioma
National Institute of Neurological Disorders and
Stroke*
Dingcai Cao, PhD
Regulatory T Cells in Malignant Glioma
National Cancer Institutes*
Dingcai Cao, PhD
Rod-Cone Interactions in Mesopic Vision
National Eye Institute
Jin-Hong Robert Chang, PhD
Endostatin-derived Short Peptides in Corneal Transplantation
Department of Veterans Affairs
Jin-Hong Robert Chang, PhD
VEGFR2 modulates corneal angiogenesis and lymphangiogenesis
National Eye Institute
Jin-Hong Robert Chang, PhD
Inhibition of VEGF receptor dimerization and signaling in corneal lymphangiogenesis
National Eye Institute
Ali Djalilian, MD
Clinical Translation of Mesenchymal Stem Cell Therapy for Corneal and Ocular Surface
Injuries
Department of Defense
Xiaoyi Raymond Gao, PhD
Mexican American Glaucoma Genetic Study
National Eye Institute
Michael Grassi, MD
Diabetes Complications Pilot and Feasibility Study: Regulators that Mediate the Cellular
Response to Chronic Hyperglycemia
National Institute of Diabetes and Digestive and
Kidney Diseases *
Michael Grassi, MD
Genomic and Genetic Studies of Diabetic Retinopathy
National Eye Institute
Sandeep Jain, MD
Molecular and cellular aspects of corneal nerve regeneration
National Eye Institute
Sandeep Jain, MD
Keratocyte Role in Guidance of Corneal Nerves
National Eye Institute
Charlotte Joslin, OD, PhD
Local Food Environments and Disparities in Ovarian Cancer Survival
National Institute on Minority Health and Health
Disparities
Iris Kassem, MD, PhD
Fibrosis and Inflammation After Anterior Segment Surgery
National Eye Institute
J. Jason McAnany, PhD
Mechanisms Limiting Visual Performance in Retinal Degenerations
National Eye Institute
Heather Moss, MD, PhD
Physiologically Based Markers of Idiopathic Intracranial Hypertension
National Eye Institute
David Pepperberg, PhD
Nanoparticle-based Photo-activator of Voltage-gated Sodium Channels
National Eye Institute
Mark Rosenblatt, MD, PhD, MBA
Mechanisms of Corneal Nerve Repair
National Eye Institute
Mark Rosenblatt, MD, PhD, MBA
Molecular and Functional Characterization of the Regenerative Potential of Slow Cycling
Corneal Epithelial Cells
National Eye Institute
Mark Rosenblatt, MD, PhD, MBA
Corneal Tissue Engineering
National Eye Institute*
Mahnaz Shahidi, PhD
Ocular Biomarkers of Microvascular, Neural and Metabolic Function in Diabetes
National Institute of Diabetes and Digestive and
Kidney Diseases
Mahnaz Shahidi, PhD
Noninvasive Imaging Of Chorioretinal Oxygen Tension
National Eye Institute
Mahnaz Shahidi, PhD
P30 Core grant for Vision Research
National Eye Institute
Mahnaz Shahidi, PhD
Investigating Optical and Neural Causes of Vision Loss
Department of Veterans Affairs
Deepak Shukla, PhD
Novel Peptides Against Modified Heparan Sulfate
National Institute of Allergy and Infectious Diseases
Deepak Shukla, PhD
Micro-nano platforms for HSV vaccine
National Institute of Allergy and Infectious Diseases
Deepak Shukla, PhD
Significance of Heparan Sulfate in HSV-1 Spread
National Institute of Allergy and Infectious Diseases
Deepak Shukla, PhD and
Beatrice Yue, PhD
Role of Optineurin in Ocular Herpes Infection
National Eye Institute
Elmer Tu, MD
Planning Grant for Parasitic Ulcer Treatment Trial Consortium
National Eye Institute*
Thasarat Vajaranant, MD
Optic Nerve Aging and Glaucoma
National Eye Institute
Beatrice Yue, PhD
Cellular Processing of Optineurin The Product of a Glaucoma Gene
National Eye Institute
Xincheng Yao, PhD
Functional Imaging of Retinal Photoreceptors
National Eye Institute
Xincheng Yao, PhD
Super-Resolution Ophthalmoscopy for In Vivo Retinal Imaging
National Eye Institute
FOUNDATION SPONSORED RESEARCH
INVESTIGATOR
PROJECT TITLE
FUNDING SOURCE
Vinay Aakalu, MD, MPH
Study of Accessory Lacrimal Gland and Precursor Cell Biology
Fight for Sight
Vinay Aakalu, MD, MPH
Development of an in vitro Model of Lacrimal Cells using Stem Cells
Midwest Eye-Banks
Vinay Aakalu, MD, MPH
Accessory Lacrimal Tissue Precursor Cell Biology
Illinois Society for the Prevention of Blindness
Vinay Aakalu, MD, MPH
Lacrimal Stem Cells and Dry Eye Research
American Society of Cataract and Refractive Surgery
Pablo Barrionuevo, PhD (Cao)
Melanopsin Photoresponse Deficit in Glaucoma
Illinois Society for the Prevention of Blindness
Joseph Bogaard (Grassi)
CYP2C9 Mediated Neuroprotection in Retinal Degenerative Disease
Illinois Society for the Prevention of Blindness
Dingcai Cao, PhD
Mesopic Visual Function Assessment and Risk Genotypes for Age-related Macular
Degeneration
Midwest Eye-Banks
Dingcai Cao, PhD
Alcohol Effects on Visual Processing in At-Risk Social Drinkers
ABMRF/The Foundation for Alcohol Research
Dingcai Cao, PhD
Postdoctoral Fellowship
International Brain Research Organization
Ali Djalilian, MD
Clinical Translation of Mesenchymal Stem Cell Trophic Factors for the Corneal Disease
in Aniridia
Vision For Tomorrow
Andrew Francis, MD (Shahidi)
Abnormalities in Retinal Layer Thickness due to Diabetes Assessed with Spectral
Domain Optical Coherence Tomography
Illinois Society for the Prevention of Blindness
Xiaoyi Raymond Gao, PhD
Fine Mapping of Genetic Loci for Central Corneal Thickness
Midwest Eye-Banks
Michael Grassi, MD
Cellular Studies of Apoptosis in RP Using Small Molecule Screening and RNA
Interference
Foundation Fighting Blindness
Joshua Hou, MD (Cortina)
Comparison of Ocular Surface Flora in Boston Keratoprosthesis Patients on Prophylactic
Vancomycin vs. Linezolid
American Society of Cataract and Refractive Surgery
Joshua Hou, MD (Cortina)
Characterization of Melt-associated Retroprosthetic Membranes in Patients with the
Boston Keratoprosthesis using Immunohistochemistry and In-situ Hybridization
Illinois Society for the Prevention of Blindness
Sandeep Jain, MD
Physician-Scientist Award
Research to Prevent Blindness, Inc.
Sandeep Jain, MD
Safety and Efficacy of DNase I Eye Drops in Dry Eye Disease
Midwest Eye-Banks
Sachin Jain, MD (Vajaranant)
Functional Measures as Surrogates for Vision-related Quality of Life in Patients with
Glaucoma
Illinois Society for the Prevention of Blindness
Charlotte Joslin, OD, PhD
Racial Disparities in Ovarian Cancer Survival
American Cancer Society
Iris Kassem, MD, PhD
Fibrin Membrane Formation and Inflammation After Pediatric Ocular Surgery
Knights Templar Eye Foundation
Behard Milani, MD (Djalilian)
The Use of Rapamycin as an Additive to Corneal Storage Media
Eye Bank Association of America
Heather Moss, MD, PhD
Ganglion Cell Function in Papilledema
Illinois Society for the Prevention of Blindness
Paul Park (Shukla)
Medical Student Fellowship: Comparative Analysis of Prophylactic and Therapeutic
Efficacies of Anti-Heparan Sulfate Peptides in Previously HSV-1 Infected Corneal Cells
Fight for Sight
Rajni Parthasarathy
(Pepperberg)
Detection and Quantification of Amyloid-Beta Protein in Eye Tissues
Illinois Society for the Prevention of Blindness
David Pepperberg, PhD
Exogenous Peptidase for Amylod-beta Degradation
BrightFocus Foundation
David Pepperberg, PhD
Nanoprosthesis for Retinal Ganglion Cell Photo-activation
Beckman Initiative for Macular Research
Mark Rosenblatt, MD, PhD, MBA
Research to Prevent Blindness, Inc. Unrestricted Departmental Grant
Research to Prevent Blindness, Inc.
Joy Sarkar, PhD (Jain)
Extracellular DNA in Tear Fluid: Innate Mechanism of Ocular Surface Inflammation
Illinois Society for the Prevention of Blindness
Mahnaz Shahidi, PhD
Senior Scientific Investigator Award
Research to Prevent Blindness, Inc.
Deepak Shukla, PhD
Developing a NSV-2 Vaginal Microbicide that also serves as a Vaccine
Center for Clinical and Translational Science
Sapna Tibrewal, MD (Jain)
Role of Neutrophils in Pathogenesis of Chronic Ocular Graft-versus-Host Disease
Illinois Society for the Prevention of Blindness
Elmer Tu, MD
Microbial Clearance Time for Acanthamoeba Keratitis
Research to Prevent Blindness, Inc.*
Thasarat Vajaranant, MD
A Feasibility Study to Assess the Accuracy of Self-Reported Glaucoma Outcomes
and Participant Interest in Ancillary Glaucoma Studies as Part of the Women’s Health
Initiative (WHI) Extension
American Glaucoma Society
Gautam Vangipuram (Moss)
Association Between Retinal Vessel Size and Short Term Intracranial Pressure Changes
in Idiopathic Intracranial Hypertension
Illinois Society for the Prevention of Blindness
Hongyu Ying, PhD
Suppression of Ocular Fibrosis by SiRNA-Nanoparticle Technology
Illinois Society for the Prevention of Blindness
Beatrice Yue, PhD
Fibril/Oligomer Formation by Optineurin in Vitro
BrightFocus Foundation
Jimmy Zhu (R. Chang)
Differential Vascular Formation in Corneal Transplant Rejection
Illinois Society for the Prevention of Blindness
*Subcontracts
OneVision | 33
CLINICAL INVESTIGATIONS AND TRIALS
CORNEA
Soledad Cortina, MD
Study of Infectious Agents in Keratoprosthesis Implanted Eyes, their Biofilm Forming Capabilities and Infectious Complications
Jose de la Cruz, MD
A Multi-Center, Randomized, Placebo-Controlled Evaluation of the Safety and Efficacy of the KXL System with VibeX (Riboflavin Ophthalmic Solution)
for Corneal Collagen Cross-Linking in Eyes with Keratoconus (KXL-005)
Sandep Jain, MD
A Phase I/II Open-Label, Single-Center, Tolerability and Preliminary Efficacy Study Of Recombinant Human Deoxyribonuclease (Rhdnase) Eye Drops
In Patients With Dry Eye Disease
Sandep Jain, MD
Symptom Analysis of Dry Eye Disease
Sandep Jain, MD
Polymorphism in Dry Eye and Depression
Sandep Jain, MD
Presence of Neutrophil Extracellular Traps (NETS) in Dry Eye Disease
Sandep Jain, MD
A Phase I/II Randomized Placebo-Controlled, Double-Blind, Single-Center, Tolerability and Preliminary Efficacy Clinical Trial of Recombinant Human
Deoxyribonuclease (Rhdnase) Eye Drops in Patients with Ocular Graft-Vs-Host Disease
Sandep Jain, MD
A Prospective Study to Identify Bio-Markers that Predict Onset and Progression of Ocular Graft-Vs-Host Disease in Patients who Receive Allogeneic
Hematopoietic Stem Cell Transplant
Elmer Tu, MD
Corneal Preservation Time Study
Elmer Tu, MD
Microbiological Clearance Time For Acanthamoeba Keratitis
GLAUCOMA
Ahmad Aref, MD
Omega-3 Fatty Acid Nutritional Supplementation in the Treatment of Ocular Surface Disease Associated with Intraocular Pressure-Lowering
Medications
Ahmad Aref, MD
Outcomes of Glaucoma Drainage Implant Surgery
Ahmad Aref, MD
Outcomes of Goniotomy Surgery
Thasarat Vajaranant, MD
A Feasibility Study to Assess the Accuracy of Self-Reported Glaucoma Outcomes and Participant Interest in Participating in Ancillary Glaucoma
Studies in Women’s Health Initiative
Thasarat Vajaranant, MD
Surgical Menopause and Risk for Premature Aging of the Optic Nerve and Glaucoma
Thasarat Vajaranant, MD
Structural Assessment in Glaucoma
Thasarat Vajaranant, MD
The Efficacy and Safety of Bimatoprost SR in Patients with Open-Angle Glaucoma or Ocular Hypertension
Thasarat Vajaranant, MD
A Randomized, Multicenter, Double-Masked, Parallel-Group Study Comparing the Safety and Efficacy of BOL-303259-X 0.024% (Latanoprostene
Bunod) Ophthalmic Solution with Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Open-Angle Glaucoma or Ocular Hypertension APOLLO Study
Thasarat Vajaranant, MD
A Double-Masked, Randomized, Multi-Center, Active-Controlled, Parallel, 3-Month Study Assessing the Safety and Ocular Hypotensive Efficacy of
AR-13324 Ophthalmic Solution, 0.02% Compared to Timolol Maleate Ophthalmic Solution, 0.5% in Patients with Elevated Intraocular Pressure
Jacob Wilensky, MD
Determining the Intraocular Presence of Benzylkonium Chloride
NEURO-OPHTHALMOLOGY
Heather Moss, MD, PhD
P. MacIntosh
Phase 2/3/ Research Study for the Treatment of Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
Heather Moss, MD, PhD;
J. McAnany; M. Shahidi
Physiologically Based Markers of Idiopathic Intracranial Hypertension
Blue Font indicates Sponsored
34
Filled rows indicates Enrolling Patients
OCULOPLASTIC SURGERY
Vinay Aakalu, MD, MPH
Study of Accessory Lacrimal Gland Biology
RETINA
Jennifer Lim, MD; F. Chau
Ocriplasmin Research to Better Inform Treatment (ORBIT)
Jennifer Lim, MD; F. Chau
A Phase 2, Randomized, Double-Masked, Placebo-Controlled, Parallel Group, Multicenter Study to Compare the Efficacy and Safety of a Chemokine
CCR2/5 Receptor Antagonist (PF-04634817) with that of Ranibizumab in Adult Subjects with Diabetic Macular Edema (Pfizer DME)
Jennifer Lim, MD; F. Chau
Study of Comparative Treatments for Retinal Vein Occlusion 2: A Multicenter, Prospective, Randomized Non-Inferiority Trial of Eyes with Macular
Edema Secondary to Central Retinal Vein Occlusion, Comparing Intravitreal Bevacizumab every 4 Weeks with Intravitreal Aflibercept every 4 Weeks
(SCORE2)
Jennifer Lim, MD; F. Chau;
W. Mieler
Argus II Retinal Prosthesis System - Post-Approval Study (PAS)
Jennifer Lim, MD; F. Chau;
W. Mieler
Argus II Retinal Prosthesis System - Humanitarian Use Device (HUD)
Jennifer Lim, MD; F. Chau
A Double-Masked, Randomized, Active-Controlled Study of the Efficacy, Safety, and Tolerability of Intravitreal Administration of VEGF Trap-Eye
(Intravitreal Aflibercept Injection [IAI]) in Patients with Macular Edema Secondary to Branch Retinal Vein Occlusion
Jennifer Lim, MD; F. Chau
A Phase 3, Double-Masked, Randomized Study of the Efficacy and Safety of Intravitreal Aflibercept to Prevent Progression to Vision-Threatening
Events in Patients with Diabetic Retinopathy (Regeneron VFGTe-OD-1411)
Jennifer Lim, MD; F. Chau
A Phase 2, Double-Masked, Randomized, Controlled, Multiple-Dose, Regimen-Ranging Study of the Efficacy and Safety of Intravitreal Regn2176-3 in
Patients with Neovascular Age-Related Macular Degeneration (Regeneron R2176-3-AMD-1417)
Jennifer Lim, MD; F. Chau
Treatment for Central-Involved Diabetic Macular Edema in Eyes with Very Good Visual Acuity (Protocol V)
Jennifer Lim, MD; F. Chau
Genes in Diabetic Retinopathy Project (Protocol Genetics)
Jennifer Lim, MD; F. Chau
Peripheral Diabetic Retinopathy (DR) Lesions on Ultrawide-field Fundus Images and Risk of DR Worsening Over Time (Protocol AA)
Jennifer Lim, MD; F. Chau
Comparative Effectiveness Study of Aflibercept, Bevacizumab and Ranibizumab for Diabetic Macular Edema (Protocol T)
Jennifer Lim, MD; F. Chau
Intravitreal Ranibizumab or Triamcinolone Acetonide in Combination with Laser Photocoagulation for Diabetic Macular Edema (Protocol I)
Jennifer Lim, MD; F. Chau
Effect of Diabetes Education during Retinal Ophthalmology Visits on Diabetes Control (Protocol M)
Jennifer Lim, MD; F. Chau
An Evaluation of Intravitreal Ranibizumab for Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy (Protocol N)
Jennifer Lim, MD; F. Chau
Genetics of AMD in African Americans
Jennifer Lim, MD; F. Chau
An Experimental Approach to Maculopathy
Jennifer Lim, MD; F. Chau
Optical Coherence Tomographical Retinal Thickness Analysis of Sickle Cell Patients
Jennifer Lim, MD; F. Chau
Spatial Temporal Imaging of Human Bulbar Conjunctival Microvascular Blood Flow in Patients with Sickle Cell Disease
Jennifer Lim, MD; F. Chau
A Retrospective Case Series to Assess the Efficacy of Anti-VEGF Therapy in the Treatment of Macular Edema Secondary to Retinal Vein Occlusion
Jennifer Lim, MD; F. Chau
Retrospective Comparison between Bevacizumab (Avastin) and Ranibizumab (Lucentis) in Diabetic Macular Edema
Jennifer Lim, MD; F. Chau
Surgical Outcomes of 25-Gauge Vitrectomy for Tractional Retinal Detachment
Jennifer Lim, MD; F. Chau
Foveal Structure Integrity and Visual Outcome in Diabetic Retinopathy
Jennifer Lim, MD; F. Chau
Evaluation of Abicipar Pegol (AGN-150998) in Patients with Decreased Vision Due to Diabetic Macular Edema (PALM)
Jennifer Lim, MD; F. Chau
Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study
Jennifer Lim, MD; F. Chau
Biomarkers in Proliferative Retinopathies (BPR)
Lawrence Ulanski, MD
Multi-Center, Randomized, Single Masked Phase 2 Study of Intravitreal Sirolimus in the Treatment of Central Geographic Atrophy Associated with
Age-Related Macular Degeneration
Lawrence Ulanski, MD
Home Vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the ForeseeHome Device
Lawrence Ulanski, MD
AMD Phenotype and Genotype Study (APGS)
To learn more about any of these investigations and trials, including how to refer patients, please call (312) 996-6590.
OneVision | 35
HONOR ROLL OF DONORS
Fiscal Year 2014
(July 1, 2013 –June 30, 2014)
$100,000+
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Research
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Alcon Laboratories, Inc.
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The Chicago Community Foundation
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Metro Environmental Contractors Inc
Midwest Maintenance Systems, Inc.
Mobile Telecommunications Ltd.
Parvin Clauss Sign Company
Patriot Capital Corporation
Pepsi Beverage Company
Mr. Michael and Mrs. Sandra Perlow
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Source North America
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Warren Retina Associates, PA
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$100-999
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Badger Land
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Bausch & Lomb
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Big Red Rooster Flow, LLC
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Brookmeade Healthcare
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Creative Retail Solutions
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Downers Grove Cellular
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Goldman Philanthropic Partnerships
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Graphics Factory, Inc.
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Ms. Susan H. Glatt
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Hodges Westside Truck Center, Inc.
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Huntley Cellular Ltd.
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Lowery Asset Consulting, LLC
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Naperville Cellular Ltd.
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N&J Gas and Food Mart Inc.
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Pinnacle Oil Holdings, LLC
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Ronnoco Coffee
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Shopco U.S.A.
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Tire Country of Jacksonville, Inc.
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VFS Concrete, Inc.
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Weiss Construction Group, LLC
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Willow Springs Lioness Club
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Woodstock Cellular Ltd.
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OneVision | 37
OPHTHALMOLOGISTS IN TRAINING
Residents
38
THIRD YEAR (Class of 2016)
SECOND YEAR (Class of 2017)
FIRST YEAR (Class of 2018)
Judy Chen, MD | CO-CHIEF RESIDENT
MD—University of Chicago
Mohsin Ali, MD
MD—Jefferson Medical College
Julie Goldman, MD
MD—Columbia University
Eric Feinstein, MD
MD—University of Virginia
Susie Chen, MD
MD—University of Wisconsin
Shilpa Gulati, MD
MD—University of Michigan
Andrew Francis, MD
MD—Boston University
Mark Dikopf, MD
MD—University of Illinois, Chicago
Robert Hyde, MD, PhD
MD/PhD—Case Western Reserve University
Abed Namavari, MD
MD—Tehran University
Siya Huo, MD
MD—Cleveland Clinic Lerner College of
Medicine
Alexander Pleet, MD
MD—University of Pennsylvania
Ketki Soin, MD | CO-CHIEF RESIDENT
MD—Jefferson Medical College
Kai Kang, MD
MD—Weill Cornell Medical College
Bailey Shen, MD
MD—Case Western Reserve University
Merina Thomas, MD
MD—Vanderbilt University
Mei Zhou, MD
MD—University of Chicago
Dan Yoon, MD
MD—New York University
Clinical Fellows
CORNEA
Claire Kelliher, MD
MD—Trinity College Dublin
Residency—Scheie Eye Institute
CORNEA
Peter Wu, MD
MD—Texas Tech University
Residency—University of
California, Davis
GLAUCOMA
Sachin Jain, MD
MD—University of Illinois, Peoria
Residency—Illinois Eye and Ear
Infirmary
NEURO-OPHTHALMOLOGY
Milena Stosic, MD
MD—University of Belgrade
Residency in Neurology—Baylor
College of Medicine
OCULOPLASTIC SURGERY
Scott Jones, MD
MD—University of Louisville
Residency—Tulane University
PEDIATRIC OPHTHALMOLOGY
Majid Rouhbakhshzaeri, MD
MD and Residency—Mashhad
University of Medical Sciences
RETINA
Michael Andreoli, MD
MD—Boston University
Residency—Illinois Eye and Ear
Infirmary
RETINA
Peter Chang, MD
MD—Tufts University
Residency—The New York Eye and
Ear Infirmary
CLASS OF 2014 RESIDENTS Front row: Drs. Kavitha Sivaraman, Randee Miller, Kevin
Patel. Back row: Drs. Janet Lim, Senad Osmanovic, Adam Prickett
CLASS OF 2015 RESIDENTS (left to right) Drs. Bryan Kim, Kaitlyn Wallace Nolan,
Michael Andreoli, Sachin Jain and Asim Farooq
RETINA
Randee Miller, MD
MD—Wayne State University
Residency—Illinois Eye and Ear
Infirmary
OneVision | 39
FACULTY PUBLICATIONS
Illinois Eye and Ear Infirmary
Aakalu VK, Patel RM, Lim J,
Setabutr P. Orbital histiocytic
sarcoma in a 2-year-old child.
Ophthal Plast Reconstr Surg.
2014 Nov-Dec;30(6):e143-5.
Abbasian J, Blair N, Shahidi
M, Kaufman L, Blair M, et al.
Macular optical coherence
tomography in patients with unilateral optic nerve hypoplasia. J
AAPOS. 2015 Feb;19(1):57-61.
Afsharkhamseh N, Movahedan
A, Djalilian AR, et al. Cataract
surgery in patients with ocular
surface disease: An update in
clinical diagnosis and treatment.
Saudi J Ophthalmol. 2014
Jul;28(3):164-7.
from natural image statistics. J
Opt Soc Am A Opt Image Sci
Vis. 2014 Apr 1;31(4):A131-9.
Aref AA, Sayyad FE, Mwanza
JC, et al. Diagnostic specificities of retinal nerve fiber layer,
optic nerve head, and macular
ganglion cell-inner plexiform
layer measurements in myopic
eyes. J Glaucoma. 2014 OctNov;23(8):487-93.
Barrionuevo PA, McAnany JJ,
Cao D, et al. Assessing rod,
cone, and melanopsin contributions to human pupil flicker responses. Invest Ophthalmol Vis
Sci. 2014 Feb 4;55(2):719-27.
Aref AA, Scott IU. Twentyfour-hour intraocular pressure
monitoring: it’s about time.
JAMA Ophthalmol. 2013
Nov;131(11):1403-4.
Agrawal H, Aref AA, Traish A,
et al. A neonate with bilateral
corneal opacities and glaucoma.
Pediat Ann.2014 Feb;43(2):60-3.
Aref AA, Sivaraman KR,
Djalilian AR. Glaucoma Drainage
Implant Surgery and Ocular
Surface Transplant Graft Preservation. Semin Ophthalmol. 2015
May;30(3):210-3.
Andreoli MT, Aakalu V, Setabutr P. Epidemiological trends in
malignant lacrimal gland tumors.
Otolaryngol Head Neck Surg.
2015 Feb;152(2):279-83.
Aref AA. Generic drugs for the
treatment of ocular conditions:
changing the treatment landscape. Expert Rev Clin Pharmacol. 2014 Sep;7(5):551-3.
Andreoli MT, Lim JI. Cotton-wool spots and retinal hemorrhages. Interferon-associated
retinopathy. JAMA Ophthalmol.
2014 Apr 1;132(4):503-4.
Asvat Y, Cao D, Africk JJ, et al.
Feasibility and effectiveness
of a community-based smoking cessation intervention in a
racially diverse, urban smoker
cohort. Am J Public Health. 2014
Sep;104 Suppl 4:S620-7.
Andreoli MT, Lim JI. Optical
coherence tomography retinal
thickness and volume measurements in X-linked retinoschisis. Am J Ophthalmol. 2014
Sep;158(3):567-73.
Andreoli MT, Yiu G, Hart L, et al.
B-scan ultrasonography following
open globe repair. Eye (Lond).
2014 Apr;28(4):381-5.
Antoine TE, Jones KS, Shukla
D, et al. Zebrafish: modeling for
herpes simplex virus infections.
Zebrafish. 2014 Feb;11(1):17-25.
Antoine TE, Shukla D. Inhibition
of myosin light chain kinase can
be targeted for the development
of new therapies against herpes
simplex virus type-1 infection.
Antivir Ther. 2014;19(1):15-29.
Antoine TE, Yakoub A, Shukla
D, et al. Zebrafish 3-O-sulfotransferase-4 generated heparan
sulfate mediates HSV-1 entry
and spread. PLoS One. 2014
Feb 3;9(2):e87302.
Aref AA, Sayyad FE, Ayres B, et
al. Acute bilateral angle
40
closure glaucoma induced by
methazolamide. Clin Ophthalmol.
2013;7:279-82.
Avery RL, Bakri SJ, Mieler WF,
et al. Intravitreal injection technique and monitoring: updated
guidelines of an expert panel.
Retina. 2014 Dec;34 Suppl
12:S1-S18.
Baldwin J, Shukla D, Tiwari
V, et al. A role for 3-O sulfated
heparan sulfate in promoting
human cytomegalovirus infection
in human iris cell. J Virol. 2015
May 1;89(9):5185-92.
Baradaran-Rafii A, Shirzadeh E,
Eslani M, et al. Optical correction of aphakia in children.
J Ophthalmic Vis Res. 2014
Jan;9(1):71-82.
Barmettler A, Nissanka N,
Rosenblatt MI, et al. Magnetic
systems for tarsorrhaphy. Ophthal Plast Reconstr Surg. 2014
Jul-Aug;30(4):305-8.
Barrionuevo PA, Cao D. Contributions of rhodopsin, cone
opsins, and melanopsin to postreceptoral pathways inferred
Beleggia F, Li Y, Maumenee IH,
et al., CRIM1 haploinsufficiency
causes defects in eye development in human and mouse.
Hum Mol Genet. 2015 Apr
15;24(8):2267-73.
Bhat PV, Goldstein DA. Dexamethasone Intravitreal Implant
(Allergan) for the Treatment of
Noninfectious Uveitis. Expert
Opinion on Orphan Drugs. 2014
Mar; 2(3): 301-10.
Bhat PV, Goldstein DA. Review
of the Latest Local Treatments
for Uveitis. Expert Review of
Ophthalmology. 2014 Oct.;9(5):
401-12.
Bourne RR, Vision Loss Expert
Group of the Global Burden of
Disease Study [Lim JI, Joslin
CE], et al., Prevalence and causes of vision loss in high-income
countries and in Eastern and
Central Europe: 1990-2010. Br J
Ophthalmol. 2014.
Boyer DS, V.I.S.I.O.N. Study
Group [Lim JI, Mieler WF], et
al. Effect of pegaptanib sodium
0.3 mg intravitreal injections
(Macugen) in intraocular
pressure: posthoc analysis from
V.I.S.I.O.N. study. Br J Ophthalmol. 2014 Nov;98(11):1543-6.
Boyer DS, Ozurdex MEAD
Study Group [Ulanski LJ], et
al. Three-year, randomized,
sham-controlled trial of dexamethasone intravitreal implant
in patients with diabetic macular
edema. Ophthalmology. 2014
Oct;121(10):1904-14.
Bressler SB, Diabetic Retinopathy Clinical Research Network
[Blair M, Lim JI], et al. Exploratory analysis of the effect of intravitreal ranibizumab or triamcinolone on worsening of diabetic
retinopathy in a randomized
clinical trial. JAMA Ophthalmol.
2013 Aug;131(8):1033-40.
Bressler SB, ; Diabetic Retinopathy Clinical Research Network
Investigators [Blair M, Lim JI],
et al. Repeated intravitreous
ranibizumab injections for
diabetic macular edema and the
risk of sustained elevation of
intraocular pressure or the need
for ocular hypotensive treatment. JAMA Ophthalmol. 2015
May;133(5):589-97.
Bui KM, Chow CC, Mieler WF.
Treatment of recalcitrant radiation maculopathy using intravitreal dexamethasone (Ozurdex)
implant. Retin Cases Brief Rep.
2014 Summer;8(3):167-70.
Bui KM, Farooq AV, Moss
HE, Lin AY, et al. Parenchymal
anaplastic astrocytoma presenting with visual symptoms due
to bilateral optic nerve sheath
involvement. J Neuroophthalmol.
2013 Sep;33(3):313-6.
Bui KM, Garcia-Gonzalez JM,
Patel SS, Lin AY, Goldstein
DA, et al. Directed conjunctival
biopsy and impact of histologic
sectioning methodology on the
diagnosis of ocular sarcoidosis. J
Ophthalmic Inflamm Infect. 2014
Mar 18;4(1):8.
Bussel II, Aref AA. Dietary
factors and the risk of glaucoma:
a review. Ther Adv Chronic Dis.
2014 Jul;5(4):188-94.
Byun YS, Sarkar J, Jain S, et al.
Keratocytes derived from spheroid culture of corneal stromal
cells resemble tissue resident
keratocytes. PLoS One. 2014
Nov 10;9(11):e112781.
Cao D, Barrionuevo PA. Estimating photoreceptor excitations
from spectral outputs of a
personal light exposure measurement device. Chronobiol Int.
2015 Mar;32(2):270-80.
Cao D, Nicandro N, Barrionuevo
PA. A five-primary photostimulator suitable for studying intrinsically photosensitive retinal ganglion cell functions in humans. J
Vis. 2015 Jan 26;15(1):15.1.27.
Cao D. S-cone discrimination
in the presence of two adapting
fields: data and model. J Opt Soc
Am A Opt Image Sci Vis. 2014
Apr 1;31(4):A65-74.
Carvalho-de-Souza JL, Treger
JS, Pepperberg DR, et al.
Photosensitivity of Neurons
Enabled by Cell-Targeted Gold
Nanoparticles. Neuron. 2015 Apr
8;86(1):207-17.
Jul-Aug;76(4):237-9.
Danis RP, AREDS2 Study Group
[Ulanski LJ, Lim J, Niec M], et
al. Methods and reproducibility
of grading optimized digital
color fundus photographs in the
Age-Related Eye Disease Study
2 (AREDS2 Report Number 2).
Invest Ophthalmol Vis Sci. 2013
Jul 8;54(7):4548-54.
Chang Q, Cao D, Grassi MA, et
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OneVision | 47
IN MEMORIUM
JOHN H. PANTON,
MD, (Res’ 57) a longtime friend and gracious benefactor to the
Department of Ophthalmology and Visual Sciences, passed
away on December 20,
2015. Mary Panton,
John’s wife of 60
years, passed away in
June, 2015. Together,
they cherished both
their family and giving back in meaningful ways.
A 1950 graduate of the University of Athens Medical
School, Dr. Panton completed his internship at Mercy Hospital-Loyola University and his residency in ophthalmology
at the University of Illinois College of Medicine. Dr. Panton
often credited his success to his UIC training.
He opened his practice in 1960, and in time was joined by
two of his sons, Drs. Peter (Res ’86) and Robert Panton
(Res ’90), and his daughter, Dr. Elizabeth Panton-Karkazis.
The Panton family have been giving to the Department of
Ophthalmology since the 1980s. Their great generosity
has benefited the Lions of Illinois Eye Research Institute,
endowed professorships and most recently the Panton
Family Professorship. In 2007, Peter and Robert Panton
joined the children of three other resident alumni to establish the Four Fathers Lecture in Ophthalmology. John
and Mary Panton also supported the IEEI Library, and the
Panton Family Scholarship in the College of Medicine.
John and Mary Panton are survived by their four children,
Peter (Estelle) Panton, Evans (Laura) Panton, Robert
(Marika) Panton, and Elizabeth (Frank) Karkazis; and 11
grandchildren.
GERHARD CLESS, a
generous benefactor
and longtime friend
of the Department
of
Ophthalmology
and Visual Sciences,
passed away on January 22, 2016, at the
age of 75. Gerhard
was an innovator, entrepreneur and family
man. Born and raised
in Germany, Gerhard
met his wife Ruth of 51 years in 1960, after which they
emigrated from Germany to Chicago. He co-founded Data
Specialties, the forerunner to Lincolnshire based Zebra
Technologies which developed the first barcode printers in
the early 1980s.
Mr. Cless and his family have been generous supporters
of the Department of Ophthalmology & Visual Sciences
since 2000. The Cless Family Foundation funded an array
of projects and needs for the department including vision
research and education programs, support for acquisitions of advanced microscopy, recruitment of retina faculty,
clinical studies in the diseases of the retina and macula,
as well as support for a retina fellowship. Prior gifts also
established the Gerhard Cless Endowed Lecture in 2003
and the Cless Best of the Best Award in 2008. The Cless
Family Professorship in Ophthalmology was established in
2013, and most recently Gerhard and Ruth Cless made a
transformative gift to establish the Cless Family Ophthalmic Surgical Training and Simulation Center.
Mr. Cless is survived by his wife, Ruth; children, Martin
(Kristin) Cless, Jennifer (Stephen) Zehr, Stephen (Anne)
Cless and Bryan (Megan) Cless; and 10 grandchildren.
INVESTITURE OF WILLIAM F. MIELER, MD, FARVO
FIRST RECIPIENT OF THE CLESS FAMILY PROFESSORSHIP
IN OPHTHALMOLOGY
Dr. Mark Rosenblatt,
Dr. William Mieler and
Dean Dimitri Azar
On November 18, 2014, Dr. William Mieler, Professor of Ophthalmology and
Vice Chair for Education, was invested as the inaugural Cless Family Professor
among members of the Cless Family, distinguished faculty and UIC Leadership.
The Cless Family Professorship was established thanks to the generosity of
the Cless Family Foundation. Endowed professorships are one of the highest
honors bestowed by the academic community. Income from these funds provides
research support and resources for program development that enable educators
to pursue projects at the forefront of their fields.
Dr. Mieler is an expert in treating diseases of the macula, retina and vitreous.
Throughout his stellar academic career Dr. Mieler has been involved in cutting
edge research, published extensively, and demonstrated an outstanding
commitment to education in ophthalmology. Dr. Mieler has received multiple
awards from the American Academy of Ophthalmology. In 2013 the Macula
Society awarded him the prestigious J. Donald Gass Medal for extraordinary
contributions to diseases of the macula.
48
IN THIS ISSUE
1
2
4
6
8
10 28 32 34 36 38 40 48 49 Leadership
Shedding Light on the “Bionic Eye”
Artificial Cornea Program Flourishes
PROSE Clinic Makes Strides
Stem Cells and Sight
Clinical Services/Faculty
Research Faculty
Sponsored Research
Clinical Investigations and Trials
Giving
Education
Publications
In Memoriam; Investiture
Cless Lab
LEADERSHIP
Mark I. Rosenblatt, MD, PhD, MBA | Professor and Department Head
Lions of Illinois/Charles I. Young Chair in Ocular Research
Joel Sugar, MD | Vice Chair for Clinical Operations
Joel Sugar MD Professor in Ophthalmology
William F. Mieler, MD, FARVO | Vice Chair for Education
Cless Family Professor in Ophthalmology
Mahnaz Shahidi, PhD | Vice Chair for Research
Morton F. Goldberg MD FACS Professor in Ophthalmology
Timothy McMahon, OD, FAAO | Vice Chair for Optometry
Professor of Ophthalmology
R. V. Paul Chan, MD, FACS | Vice Chair for Global Ophthalmology
Professor of Ophthalmology
CLESS FAMILY OPHTHALMIC SURGICAL TRAINING
AND SIMULATION CENTER
The Illinois Eye and Ear Infirmary is known as a leader in the field of ophthalmic training in the region and in the
nation. One component of this leadership is providing the highest level of surgical training that is available. This
year we inaugurated the 9 station state-of-the-art Cless Family Ophthalmic Surgical Training and Simulation
Center (Cless Lab), the premier center for ophthalmic surgical training in the Midwest. The Cless Lab will be
home to surgical training courses, webcasting and live surgery streaming as well as surgical simulation technology. A generous investment made by the Cless Family Foundation, along with support from faculty and alumni,
made this vision a reality. Establishing the Cless Lab is an enormous advancement in how we train our residents
and surgical fellows. It is an active learning environment allowing for a virtual-reality simulation experience within
which attention to the finest, most minute details, such as the careful orchestration of hand and foot instrument
manipulation, can be perfected without putting patients at risk. It will no doubt significantly increase trainees’
aptitude and confidence when performing in a live operating room.
The virtual connections this equipment makes possible will enable us to examine how fellow surgeons from all
corners of the world do work, and repeat it right here. This exposure to new information and practices will fuel
the innovation and breakthroughs that will happen here first. And, when they do, we can share them with the rest
of the world right from the Cless Lab. We now are able to provide services few places in the world can offer. Our
faculty, residents, fellows, alumni and local ophthalmologists can learn more, innovate faster and pioneer surgical
curriculum because of these connections.
CREDITS
Writers
Lisa Holton
Margaret Doyle
Editor
Laurie Walker
Designer
Lisa Birmingham
Contributors
Margaret Chervinko, Lauren Hughes,
Cristina Lee, Kristen Scheurich,
Laurie Walker
Photography
Cathy Carroll, Joshua Clark,
Roberta Dupuis-Devlin,
Mark Janowicz
On the cover
Visionary by Gwyn Newcombe
Left to right: Drs. Sugar, McMahon, Shahidi, Mieler and Rosenblatt—not pictured, Dr. Chan
1855 West Taylor Street
Chicago, IL 60612
Non-Profit Org.
U.S. Postage
PAID
Permit No. 4860
symposia & events 2016
February 20-26, 2016
9th Annual Illinois Eye Review
Friday, April 22, 2016
9th Annual Retina Symposium
Wednesday, May 25, 2016
2016 Spring Glaucoma Symposium
Friday, June 17, 2016
40th Annual Alumni / Resident Day
Sunday, October 16, 2016
Alumni Reception at the AAO Meeting
Saturday, October 22, 2016
The Chicago Chronic GVHD Meeting
http://eyecare.uic.edu l www.chicago.medicine.uic.edu/eye
Proud Community Partner
ONE VISION2014-15
Department of Ophthalmology and Visual Sciences
Illinois Eye and Ear Infirmary
University of Illinois College of Medicine
AND EAR INFIRMARY