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PowerPoint® Lecture Slides
Prepared by Patty Bostwick-Taylor,
Florence-Darlington Technical College
NEED TO SHORTEN
CHAPTER
7
The Nervous
System
© 2012 Pearson Education, Inc.
Functions of the Nervous System
•Sensory input =
•Why: monitor changes inside & outside body
•Changes = stimuli
•Integration =
•Motor output =
•Activates muscles or glands
© 2012 Pearson Education, Inc.
© 2012 Pearson Education, Inc.
Figure 7.1
Organization of the Nervous System
Structural Classification
•Central nervous system (CNS) =
•Function
© 2012 Pearson Education, Inc.
Structural Classification …
• Peripheral nervous system (PNS) =
• Spinal nerves:
• Cranial nerves:
• Functions:
© 2012 Pearson Education, Inc.
© 2012 Pearson Education, Inc.
Figure 7.2
Functional Classification
Peripheral N.S. …
•Sensory (afferent):
•Motor (efferent):
•For muscles
•For Organs
© 2012 Pearson Education, Inc.
Nervous Tissue Structure & Function:
Nervous Tissue Cells
•Neuroglia (glial): Support cells
•General functions
•Support
•Insulate
•Protect
© 2012 Pearson Education, Inc.
Nervous Tissue Structure and Function …
Neurons
•Function:
•Parts–
•Cell body &
• Processes
•Cell body
•Nissl bodies = rough endoplasmic reticulum
•Nucleus
© 2012 Pearson Education, Inc.
Mitochondrion
Dendrite
Cell
body
Nissl substance
Axon
hillock
Axon
Neurofibrils
Nucleus
Collateral
branch
One
Schwann cell
Axon
terminal
Node of
Ranvier
Schwann cells,
forming the myelin
sheath on axon
(a)
© 2012 Pearson Education, Inc.
Figure 7.4a
Neuron cell body
Dendrite
(b)
© 2012 Pearson Education, Inc.
Figure 7.4b
Nervous Tissue: Neurons
•Processes =
•Dendrites:
•#
•Axons:
•#
•Axon Hillock
•Axon Terminal
• Contain Vessicles w/:
• Neurotransmitters
© 2012 Pearson Education, Inc.
Mitochondrion
Dendrite
Cell
body
Nissl substance
Axon
hillock
Axon
Neurofibrils
Nucleus
Collateral
branch
One
Schwann cell
Axon
terminal
Node of
Ranvier
Schwann cells,
forming the myelin
sheath on axon
(a)
© 2012 Pearson Education, Inc.
Figure 7.4a
Neurons …
•Axons …
• Synaptic cleft—gap between adjacent
neurons
• Synapse—junction between nerves
© 2012 Pearson Education, Inc.
Nervous Tissue: Neurons
•Myelin sheath =
•Nodes of Ranvier—
•CNS and PNS
© 2012 Pearson Education, Inc.
Schwann cell
cytoplasm
Axon
Schwann cell
plasma membrane
Schwann cell
nucleus
(a)
(b)
Neurilemma
Myelin
sheath
(c)
© 2012 Pearson Education, Inc.
Figure 7.5
Neurons …
Terminology
•Location cell bodies & Dendrites:
•Gray Matter
•Nuclei =
•Ganglia =
•Location AXONS
•White matter =
•Tracts =
•Nerves =
© 2012 Pearson Education, Inc.
Neurons …
Functional Classification of Neurons
•Sensory (afferent) neurons =
•Motor (efferent) neurons =
© 2012 Pearson Education, Inc.
Central process (axon)
Cell
body
Sensory
neuron
Spinal cord
(central nervous system)
Ganglion
Dendrites
Peripheral
process (axon)
Afferent
transmission
Interneuron
(association
neuron)
Peripheral
nervous system
Receptors
Efferent transmission
Motor neuron
To effectors
(muscles and glands)
© 2012 Pearson Education, Inc.
Figure 7.6
© 2012 Pearson Education, Inc.
Figure 7.7a
© 2012 Pearson Education, Inc.
Figure 7.7b
© 2012 Pearson Education, Inc.
Figure 7.7c
© 2012 Pearson Education, Inc.
Figure 7.7d
© 2012 Pearson Education, Inc.
Figure 7.7e
Functional Classification of Neurons
•Interneurons (association neurons)
•Found in neural pathways in the central
nervous system
•Connect sensory and motor neurons
© 2012 Pearson Education, Inc.
Central process (axon)
Cell
body
Sensory
neuron
Spinal cord
(central nervous system)
Ganglion
Dendrites
Peripheral
process (axon)
Afferent
transmission
Interneuron
(association
neuron)
Peripheral
nervous system
Receptors
Efferent transmission
Motor neuron
To effectors
(muscles and glands)
© 2012 Pearson Education, Inc.
Figure 7.6
Structural Classification of Neurons
•Multipolar neurons—many extensions from the
cell body
•All motor and interneurons
© 2012 Pearson Education, Inc.
Cell body
Axon
Dendrites
(a) Multipolar neuron
© 2012 Pearson Education, Inc.
Figure 7.8a
Structural Classification of Neurons
•Bipolar neurons—one axon and one dendrite
•nose and eye
© 2012 Pearson Education, Inc.
Cell body
Dendrite
Axon
(b) Bipolar neuron
© 2012 Pearson Education, Inc.
Figure 7.8b
Structural Classification of Neurons
•Unipolar neurons—have a short single
process leaving the cell body
•Sensory neurons found in PNS ganglia
© 2012 Pearson Education, Inc.
Dendrites
Cell body
Short single
process
Axon
Peripheral
process
Central
process
(c) Unipolar neuron
© 2012 Pearson Education, Inc.
Figure 7.8c
PHYSIOLOGY: Nerve Impulses
Functional Properties of Neurons
•Irritability
•Ability to respond to stimuli
•Conductivity
•Ability to transmit an impulse
© 2012 Pearson Education, Inc.
Nerve Impulses
• Action Potential = Nerve Impulse
• The WAVE: movement of arms = ion movement
• Stimulus
• Ions move a short distance across the plasma
membrane
• Successive regions of the membrane have ion
movement– from point of stimulus to axon
terminal
© 2012 Pearson Education, Inc.
Nerve Impulses = Action Potential
•Resting neuron
•The plasma membrane charge is polarized
•Fewer positive ions are inside the cell than
outside the cell
• Inside is negative relative to outside
and outside is positive
+
POSITIVE CHARGE
__
+
__
NEGATIVE CHARGE
© 2012 Pearson Education, Inc.
+
__
Nerve Impulses …
• Ion distribution differs inside vs. outside
• Inside: more K
• Outside: more Na
• Cell Membrane impermeable to ions when neuron
is at rest
+ Na+
_
Na+
K+ K+
© 2012 Pearson Education, Inc.
K+
Na+ Na+ Na+
K+
K+
Na+
K+ K+
Na+
Nerve Impulses …
STIMULUS
_
Na+
+ Na+ K+
K+
Na+ Na+ Na+
Na+
K+ K+ K+
(1) Stimulus
(2) Depolarization = Sodium moves inside neuron
The membrane is now permeable to sodium as sodium
channels open
Sodium (Na+) flows inside the membrane
© 2012 Pearson Education, Inc.
Nerve Impulses …
(3) Repolarization
•Potassium ions leave neuron which
repolarizes the membrane
•Repolarization involves restoring the inside
of the membrane to a negative charge and
the outer surface to a positive charge
+
© 2012 Pearson Education, Inc.
K+ Na+ Na+ Na+ Na+ Na+
_ Na+ K+
K+ K+ K+ K+
Nerve Impulses …
(4) Successive regions of the membrane have ion
movement– from point of stimulus to axon
terminal
K+ K+ Na+ Na+ Na+ Na+
Na+ Na+ K+ K+ K+ K+
© 2012 Pearson Education, Inc.
Nerve Impulses …
(5) Redistribution of ions
Initial ionic conditions are restored using the sodium-potassium
pump.
Three sodium ions are ejected while two potassium ions are
returned
Na+ K+ Na+ Na+ Na+ Na+
K+ Na+ K+ K+ K+ K+
© 2012 Pearson Education, Inc.
Na+ K+ Na+ Na+ Na+ Na+
K+ Na+ K+ K+ K+ K+
Na+ Na+ K+ Na+ Na+ Na+ Na+
K+ K+ Na+ K+ K+ K+ K+
Na+ Na+ Na+ K+ Na+ Na+Na+
K+ K+ K+ Na+ K+ K+ K+
Na+ Na+ Na+ Na+ K+ Na+ Na+
K+ K+ K+ K+ Na+ K+ K+
© 2012 Pearson Education, Inc.
Figure 11.12 Propagation of an action potential (AP).
© 2012 Pearson Education, Inc.
Nerve Impulses
•Impulses travel faster when fibers have a
myelin sheath
© 2012 Pearson Education, Inc.
Transmission of a Signal at Synapses
•When action potential reaches the axon
terminal, calcium channels open
• Calcium
diffuses in
Axon terminal
Ca+
Ca+
Dendrite
© 2012 Pearson Education, Inc.
Action
potential
arrives.
Ca+
Ca+
Transmission of a Signal at Synapses …
(1) Calcium causes vesicles to
move to axonal membrane
Axon terminal
Vesicles
1 Ca+
Dendrite
© 2012 Pearson Education, Inc.
Ca+
Ca+
Ca+
Figure 7.10, step 1
2 Vesicle
fuses with
plasma
membrane.
Ca+
Synaptic
cleft
Axon terminal of
Ca+
Ca+
Neurotransmitter
molecules
Dendrite
© 2012 Pearson Education, Inc.
Figure 7.10, step 2
2 Vesicle Transmitting neuron
fuses with
plasma
3 Neurotransmembrane.
mitter is
Ca+ released into
synaptic cleft.
Synaptic
cleft
Neurotransmitter
molecules
Dendrite
Receiving neuron
© 2012 Pearson Education, Inc.
Figure 7.10, step 3
Transmission of a Signal at Synapses
(3) Neurotransmitters diffuse across to dendrite
of receiving cell
Axon Terminal
Dendrite
© 2012 Pearson Education, Inc.
2 Vesicle
fuses with
plasma
membrane.
AXON TERMINAL
Ca+
4
3 NeurotransNeurotransmitter binds
mitter is
to Receptor
released into
synaptic cleft. .
Synaptic
cleft
Receptors
Dendrite
© 2012 Pearson Education, Inc.
Figure 7.10, step 4
(4) Receptors: a) are proteins that bond with
Neurotransmitter
© 2012 Pearson Education, Inc.
Transmission of a Signal at Synapses
(5) If enough neurotransmitter is released, the 2nd
neuron will send its own Action potential
Neurotransmitter
Ion
Receptor
© 2012 Pearson Education, Inc.
5 Ion channel opens.
6 Receptor channel closes.
Ion
(7) Neurotransmitter is
broken down and
released.
© 2012 Pearson Education, Inc.
Figure 7.10, step 6
The Reflex Arc– Simplest Function
•Five elements:
•Sensory receptor:
•Sensory neuron:
•Integration center (CNS)--interneuron:
•Motor neuron:
•Effector organ:
© 2012 Pearson Education, Inc.
CNS Functioning– Simplest
•Somatic reflexes
•Reflexes that stimulate the ____________
•Examples:
•Autonomic reflexes
•Regulate the activity of ___________
•Examples:
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Three-Neuron Reflex Arc
•Three-neuron reflex arcs
•Have all 5 elements
•Example: Flexor (withdrawal) reflex
2
1
Stimulus
3
4
5
© 2012 Pearson Education, Inc.
STIMULUS
Receptor
Sensory Neuron
Integration Center-- CNS
Motor Neuron
Effector
1 Sensory receptor
2 Sensory (afferent) neuron
3 Interneuron
4 Motor (efferent) neuron
5 Effector organ
© 2012 Pearson Education, Inc.
Figure 7.11c
1 Sensory (stretch) receptor
2 Sensory (afferent) neuron
3
4 Motor (efferent) neuron
5 Effector organ
© 2012 Pearson Education, Inc.
Figure 7.11b, step 5
Central Nervous System (CNS)
Parietal lobe
Brain
Left cerebral
hemisphere
Frontal
lobe
Occipital
lobe
Temporal
lobe
Cephalad
Caudal
(b)
© 2012 Pearson Education, Inc.
Brain
stem
Cerebellum
Figure 7.13b
Central Nervous System (CNS)
Brain Regions
•**Cerebrum
•Thalamus,
•**Hypothalamus
•**Brain stem
•**Cerebellum
© 2012 Pearson Education, Inc.
Cerebrum
• Cerebral Hemispheres
• Cerebral Cortex
• Primary somatic sensory area
• Primary motor area
Primary motor area
© 2012 Pearson Education, Inc.
Primary somatic sensory
area
•Anterior Association Area
•Posterior Association Area
•Broca’s area
•Speech Area
Anterior
association area
• Working memory
and judgment
• Problem
solving
• Language
comprehension
Broca’s area
(motor speech)
(c)
© 2012 Pearson Education, Inc.
Speech/language
(outlined by dashes)
Posterior association
area
Primary motor area
Premotor area
Anterior
association area
• Working memory
and judgment
• Problem
solving
• Language
comprehension
Broca’s area
(motor speech)
Olfactory
area
Central sulcus
Primary somatic sensory
area
Gustatory area (taste)
Speech/language
(outlined by dashes)
Posterior association
area
Visual area
Auditory area
(c)
© 2012 Pearson Education, Inc.
Figure 7.13c
Cerebrum …
•Corpus Callosum
Superior
corpus callosum
Basal nuclei
Pons
Medulla oblongata
© 2012 Pearson Education, Inc.
Longitudinal fissure
Lateral
ventricle
Basal nuclei
(basal
ganglia)
Superior
Association fibers
Commissural fibers
(corpus callosum)
Corona
radiata
Fornix
Thalamus
Internal
capsule
Third
ventricle
Pons
Projection
fibers
Medulla oblongata
© 2012 Pearson Education, Inc.
Figure 7.15
•Thalamus
•Hypothalamus
Thalamus &
Hypothalamus
(b) Adult
brain
© 2012 Pearson Education, Inc.
Brain Stem
•Pons
•Medulla oblongata
© 2012 Pearson Education, Inc.
Cerebellum
© 2012 Pearson Education, Inc.
Items Associated with the Brain
•Cerebrospinal Fluid
•Meninges
•Dura Mater
•Arachnoid Mater & Subarachnoid Space
•Pia Mater
Skin of scalp
Periosteum
Bone of skull
Superior
sagittal sinus
Subdural
space
Subarachnoid
space
(a)
© 2012 Pearson Education, Inc.
Periosteal
Meningeal
Dura
mater
Arachnoid mater
Pia mater
Arachnoid villus
Blood
vessel
Falx cerebri
(in longitudinal
fissure only)
Occipital lobe
Tentorium
cerebelli
Cerebellum
Arachnoid mater
over medulla
oblongata
(b)
© 2012 Pearson Education, Inc.
Skull
Scalp
Superior
sagittal sinus
Dura mater
Transverse
sinus
Temporal
bone
Figure 7.17b
•Ventricles
•Blood-brain barrier
Lateral ventricle
Anterior horn
Septum
pellucidum
Inferior
horn
Lateral
aperture
Interventricular
foramen
Third ventricle
Cerebral aqueduct
Fourth ventricle
Central canal
© 2012 Pearson Education, Inc.
Lateral ventricle
Anterior horn
Posterior
horn
Interventricular
foramen
Third ventricle
Inferior horn
Cerebral aqueduct
Median
aperture
Fourth ventricle
Lateral
aperture
Central canal
(b) Left lateral view
© 2012 Pearson Education, Inc.
Figure 7.18b
CSF Circulation
4
Superior
sagittal sinus
Arachnoid villus
Subarachnoid space
Arachnoid mater
Meningeal dura mater
Periosteal dura mater
Right lateral ventricle
(deep to cut)
Choroid plexus
Corpus
callosum
1
Interventricular
foramen
Third ventricle
3
Cerebral aqueduct
Lateral aperture
Fourth ventricle
Median aperture
Central canal
of spinal cord
(c) CSF circulation
Choroid plexus
of fourth ventricle
2
1 CSF is produced by the
choroid plexus of each ventricle.
2 CSF flows through the ventricles
and into the subarachnoid space via
the median and lateral apertures.
Some CSF flows through the central
canal of the spinal cord.
3 CSF flows through the
subarachnoid space.
4 CSF is absorbed into the dural
venous sinuses via the arachnoid
villi.
© 2012 Pearson Education, Inc.
Figure 7.18c
Central Nervous System …
Spinal Cord
•from foramen magnum
to 2nd lumbar vertebra
• then as a collection of
spinal nerves
© 2012 Pearson Education, Inc.
• Functions:
• Relays information
between ____ & _____.
• Sensory
• Motor
• Spinal Reflexes
© 2012 Pearson Education, Inc.
Spinal Cord Anatomy
•Meninges
© 2012 Pearson Education, Inc.
Dorsal root
ganglion
White matter
Central canal
Dorsal (posterior)
horn of gray matter
Lateral horn of
gray matter
Spinal nerve
Dorsal root of
spinal nerve
Ventral root
of spinal nerve
Ventral (anterior)
horn of gray matter
Pia mater
Arachnoid mater
Dura mater
© 2012 Pearson Education, Inc.
Figure 7.21
Peripheral Nervous System (PNS)
•PNS = Nerves and
ganglia
•connective tissue
© 2012 Pearson Education, Inc.
Axon
Myelin sheath
Endoneurium
Perineurium
Epineurium
Fascicle
Blood
vessels
© 2012 Pearson Education, Inc.
Figure 7.23
PNS: Classification of Nerves
•Mixed nerves =
•Sensory (afferent) nerves =
•Motor (efferent) nerves =
© 2012 Pearson Education, Inc.
PNS: Cranial Nerves
•Twelve pairs of nerves
•Most are mixed
•three are sensory only
© 2012 Pearson Education, Inc.
Figure 13.6a Location and function of cranial nerves.
Filaments of
olfactory nerve (I)
Frontal lobe
Olfactory bulb
Olfactory tract
Optic nerve (II)
Optic chiasma
Temporal lobe
Optic tract
Oculomotor
nerve (III)
Trochlear
nerve (IV)
Infundibulum
Trigeminal
nerve (V)
Abducens
nerve (VI)
Cerebellum
Medulla oblongata
© 2012 Pearson Education, Inc.
Facial nerve (VII)
Vestibulocochlear
nerve (VIII)
Glossopharyngeal
nerve (IX)
Vagus nerve (X)
Accessory nerve (XI)
Hypoglossal nerve (XII)
III Oculomotor
IV Trochlear
VI Abducens
I Olfactory
II Optic
V Trigeminal
V Trigeminal
VII Facial
Vestibular
branch
Cochlear
branch
VIII Vestibulocochlear
X Vagus
IX Glossopharyngeal
XII Hypoglossal
© 2012 Pearson Education, Inc.
XI Accessory
Figure 7.24
PNS: Cranial Nerves
•I Olfactory nerve—sensory for smell
•II Optic nerve—sensory for vision
I
II
© 2012 Pearson Education, Inc.
PNS: Cranial Nerves
•V Trigeminal nerve—sensory for the face;
motor fibers to chewing muscles
X Vagus nerves—sensory and motor fibers
for pharynx, larynx, and viscera
V
X
© 2012 Pearson Education, Inc.
31 Paired Spinal Nerves
Cervical
nerves
Thoracic
nerves
Lumbar
nerves
Sacral
nerves
C1
2
3
4
5
6
7
8
T1
2
3
4
5
6
7
8
9
10
11
Ventral rami form
cervical plexus
(C1 – C5)
Ventral rami form
brachial plexus
(C5 – C8; T1)
No plexus
formed
(intercostal
nerves)
(T1 – T12)
12
L1
2
3
4
Ventral rami form
lumbar plexus
(L1 – L4)
5
(a)
© 2012 Pearson Education, Inc.
S1
2
3
4
Ventral rami form
sacral plexus
(L4 – L5; S1 – S4)
Superior gluteal
Sciatic Nerve
Phrenic Nerve
Inferior gluteal
Pudendal
Sciatic
Posterior femoral
cutaneous
Common fibular
Tibial
Sural (cut)
Deep fibular
Superficial fibular
Plantar branches
© 2012 Pearson Education, Inc.
Figure 13.12c The sacral plexus.
Gluteus maximus
Piriformis
Inferior gluteal
nerve
Common fibular
nerve
Tibial nerve
Pudendal nerve
Posterior femoral
cutaneous nerve
Sciatic nerve
Cadaver photo
© 2012 Pearson Education, Inc.
Peripheral NS …
PNS: Autonomic Nervous System
• Motor subdivision of the PNS
• Involuntary
•Two subdivisions
© 2012 Pearson Education, Inc.
PNS: Autonomic Functioning …
•Sympathetic—STRESS
“fight or flight”
•Exercise, excitement, emergency,
embarrassment
•unusual stimulus
•Increases:
•
•
•
•
•
© 2012 Pearson Education, Inc.
Sympathetic …
•Decreases activities of unnecessary organ
systems during stress
•
•
© 2012 Pearson Education, Inc.
Parasympathetic
Sympathetic
Eye
Eye
Brain stem
Salivary
glands
Heart
Skin
Cranial
nerves
Sympathetic
ganglia
Salivary
glands
Cervical
Lungs
Lungs
T1
Heart
Stomach
Thoracic
Stomach
Pancreas
Pancreas
L1
Liver and
gallbladder
Lumbar
Pelvic
splanchnic
nerves
© 2012 Pearson Education, Inc.
Adrenal
gland
Bladder
Bladder
Genitals
Liver
and gallbladder
Genitals
Sacral nerves (S2 – S4)
Figure 7.28
PNS: Autonomic Functioning
• Parasympathetic—PEACE
“housekeeping”
•necessary body functions
•Increases activities of:
•
•
• Decreases activities of Stress Organ
Systems
© 2012 Pearson Education, Inc.
© 2012 Pearson Education, Inc.
Figure 7.2
•END OF PPT
© 2012 Pearson Education, Inc.
PHYSIOLOGY: Reflexes
The Reflex Arc
•The simplest type of processing
•Reflex—rapid, predictable, and involuntary
response to a stimulus
•Occurs over pathways called reflex arcs
•Reflex arc—direct route from a sensory
neuron, to an interneuron, to an effector
© 2012 Pearson Education, Inc.
Stimulus at distal
end of neuron
Spinal cord
(in cross section)
Skin
2 Sensory neuron
1 Receptor
4 Motor neuron
5 Effector
3 Integration
center
Interneuron
(a) Five basic elements of reflex arc
© 2012 Pearson Education, Inc.
Figure 7.11a
Withdrawal Reflexes
1 Sensory receptor
© 2012 Pearson Education, Inc.
Figure 7.11c, step 1
1 Sensory receptor
© 2012 Pearson Education, Inc.
2 Sensory (afferent) neuron
Figure 7.11c, step 2
1 Sensory receptor
2 Sensory (afferent) neuron
3 Interneuron
© 2012 Pearson Education, Inc.
Figure 7.11c, step 3
1 Sensory receptor
2 Sensory (afferent) neuron
3 Interneuron
4 Motor (efferent) neuron
© 2012 Pearson Education, Inc.
Figure 7.11c, step 4
1 Sensory receptor
2 Sensory (afferent) neuron
3 Interneuron
4 Motor (efferent) neuron
5 Effector organ
© 2012 Pearson Education, Inc.
Figure 7.11c, step 5
[Na+]
+
–[K ]
–
+
+
© 2012 Pearson Education, Inc.
1 Resting membrane is polarized. In the resting state, the
external face of the membrane is slightly positive; its internal
face is slightly negative. The chief extracellular ion is sodium
(Na+), whereas the chief intracellular ion is potassium (K+).
The membrane is relatively impermeable to both ions.
Figure 7.9, step 1
Na+
+
+
–
–
+
© 2012 Pearson Education, Inc.
2 Stimulus initiates local depolarization. A stimulus
changes the permeability of a local "patch" of the membrane,
and sodium ions diffuse rapidly into the cell. This changes the
polarity of the membrane (the inside becomes more positive;
the outside becomes more negative) at that site.
Figure 7.9, step 2
Na+
+
+
–
–
+
© 2012 Pearson Education, Inc.
3 Depolarization and generation of an action potential.
If the stimulus is strong enough, depolarization causes
membrane polarity to be completely reversed and an action
potential is initiated.
Figure 7.9, step 3
–
+
+
–
© 2012 Pearson Education, Inc.
4 Propagation of the action potential. Depolarization of
the first membrane patch causes permeability changes in the
adjacent membrane, and the events described in step 2 are
repeated. Thus, the action potential propagates rapidly along
the entire length of the membrane.
Figure 7.9, step 4
+
K+
+
–
+
–
© 2012 Pearson Education, Inc.
5 Repolarization. Potassium ions diffuse out of the cell as
the membrane permeability changes again, restoring the
negative charge on the inside of the membrane and the
positive charge on the outside surface. Repolarization occurs
in the same direction as depolarization.
Figure 7.9, step 5
Na+
Na+
Na+ Diffusion
K+ Diffusion
Cell
exterior
Cell
interior
© 2012 Pearson Education, Inc.
Na+
Na+ – K+
pump
K+
K+
K+
Plasma
membrane
6 Initial ionic conditions restored. The ionic conditions
of the resting state are restored later by the activity of the
sodium-potassium pump. Three sodium ions are ejected for
every two potassium ions carried back into the cell.
K+
Figure 7.9, step 6
PHYSIOLOGY: Reflexes
The Reflex Arc
•The simplest type of processing
•Reflex—rapid, predictable, and involuntary
response to a stimulus
•Occurs over pathways called reflex arcs
•Reflex arc—direct route from a sensory
neuron, to an interneuron, to an effector
© 2012 Pearson Education, Inc.
• Brain Regions
• Cerebrum, Cerebral hemispheres, Cerebral Cortex,
•
Parietal lobe, Primary Somatic Sensory Area,
•
Occipital lobe,
•
Temporal Lobe,
•
Frontal Lobe,
•
Special Regions: Primary Somatic Sensory Area, Primary Motor area,
Corticospinal Tract, Brocas’s area, Anterior Association Area, Posterior
Association Area, Speech Area
•
Corpus Callosum
•
Basal Nuclei (Basal Ganglia)
•
• Diencephalon
•
Thalamus
•
Hypothalamus, Limbic System, Pituitary Gland
•
• Brain Stem
•
Midbrain
•
Pons
•
Medulla Oblongata
•
Reticular Activating System
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•
Cerebellum
•
• Items Associated with the Brain
•
Meninges
•
Dura Mater
•
Arachnoid Mater, Subarachnoid Space
•
Pia Mater
•
Cerebrospinal Fluid
•
Ventricles
•
Blood-Brain Barrier
•
• Brain Dysfunctions
•
Hydrocephalus
•
Concussion
•
Contusion
•
Cerebral Edema
•
Cerebrovascular Accidents
•
Transient Ischemic Attack
•
Alzheimer’s Disease
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Precentral
gyrus
Central sulcus
Postcentral gyrus
Parietal lobe
Frontal lobe
Parieto-occipital
sulcus (deep)
Lateral sulcus
Occipital lobe
Temporal lobe
Cerebellum
Pons
Medulla
oblongata
Cerebral cortex
(gray matter)
Gyrus
Spinal
cord
Sulcus
Fissure
(a deep sulcus)
(a)
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Cerebral
white
matter
Figure 7.13a
Cerebrum
Thalamus +
Hypothalamus
Cerebellum
Brain stem
(b) Adult brain
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Figure 7.12b
Cerebral hemisphere
Corpus callosum
Choroid plexus of third
ventricle
Occipital lobe of
cerebral hemisphere
Thalamus
(encloses third ventricle)
Pineal gland
(part of epithalamus)
Corpora
quadrigemina
Midbrain
Cerebral
aqueduct
Third ventricle
Anterior
commissure
Hypothalamus
Optic chiasma
Pituitary gland
Mammillary body
Pons
Medulla oblongata
Spinal cord
Cerebral peduncle
of midbrain
Fourth ventricle
Choroid plexus
Cerebellum
(a)
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Figure 7.16a
Occipital lobe
Tentorium
cerebelli
Cerebellum
Arachnoid mater
over medulla
oblongata
(b)
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Skull
Scalp
Superior
sagittal sinus
Dura mater
Transverse
sinus
Temporal
bone
Figure 7.17b
PNS: Differences Between Somatic
and Autonomic Nervous Systems
Somatic Nervous
System
Autonomic Nervous
System
Nerves
One-neuron; it
originates in the CNS
and axons extend to
the skeletal muscles
served
Two-neuron system
consisting of
preganglionic and
postganglionic
neurons
Effector organ
Skeletal muscle
Smooth muscle,
cardiac muscle,
glands
Subdivisions
None
Sympathetic and
parasympathetic
Neurotransmitter
Acetylcholine
Acetylcholine,
epinephrine,
norepinephrine
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